CN103055157A - Compound dendrobium huoshanense, cistanche and ganoderma granules and production process thereof - Google Patents
Compound dendrobium huoshanense, cistanche and ganoderma granules and production process thereof Download PDFInfo
- Publication number
- CN103055157A CN103055157A CN2012105825124A CN201210582512A CN103055157A CN 103055157 A CN103055157 A CN 103055157A CN 2012105825124 A CN2012105825124 A CN 2012105825124A CN 201210582512 A CN201210582512 A CN 201210582512A CN 103055157 A CN103055157 A CN 103055157A
- Authority
- CN
- China
- Prior art keywords
- ganoderma
- rong
- suddenly
- compound recipe
- measure used
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses compound dendrobium huoshanense, cistanche and ganoderma granules and a production process thereof; and the formula thereof comprises the following ingredients, by weight: 10-15% of dendrobium huoshanense, 20-25% of mulberry, 5-10% of cistanche, 5-10% of ganoderma, and 40-60% of functional oligosaccharide. According to the invention, effective extract and use of medicinal ingredients in dendrobium huoshanense, mulberry, cistanche, and ganoderma are realized; dissolution rates of active ingredients (water-soluble components, and alcohol-soluble components) of dendrobium huoshanense, mulberry, cistanche, and ganoderma are improved; and the granules are instant to dissolve, convenient to take and good in effect.
Description
Technical field
The present invention relates to Chinese medicine health care product, specifically relate to a kind of prescription and production technology of herbal mixture granule.
Background technology
Herba Dendrobii contains the materials such as polysaccharide, alkaloid, aminoacid, and the trace element such as calcic, potassium, sodium, magnesium, zinc, ferrum, manganese, selenium, copper, chromium, nickel.Through Chinese Medicine institute polyoses content that medicinal plants is identified be 38.974%, total alkaloids is 0.03%, can improve the human body immunity, and the organ diseases such as human body eye, pharynx, lung, stomach, intestinal, kidney are had special efficacy.Be used as medicine with it, blood sugar lowering arranged, suppress cardiovascular disease, enhancing human body immunity power and anticancer usefulness; With for tea, can cleaning throat and moistening larynx, sore throat relieving makes eye bright, expelling summer-heat QI invigorating, nourishing the stomach heat clearing away, because its effect is peculiar, market is rare, have the title of " Chinese Herba mesonae chinensis ", " Herba Hylothelephii Verticillati ".
Fructus Mori contains glucose, tannin, succinic acid, cyanidin, calcareous, inorganic salt, vitamin (A, B, C), malic acid, succinic acid, tartaric acid, pigment etc.The blue or green Fructus Mori of immaturity contains cyanic acid, carotene, adenine, choline, Isoquercitrin, trigonelline, ergosterol, vitamin B1, sugar, tannin.
Nature and flavor: sweet; Acid; Cold in nature.Gui Jing: liver; Kidney channel, heart channel.Function cures mainly: nourishing YIN and benefiting blood; Promote the production of body fluid; Intestine moistening.Having a dizzy spell of main deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; The dryness of the intestine constipation.
Herba Cistanches contains the compositions such as abundant alkaloid, crystalline neutral substance, aminoacid, trace element, vitamin.Energy kidney-replenishing, benefiting essence-blood can suppress the appearance of " yang deficiency " symptom, prevent from losing weight.Can effectively prevent, treat the diseases such as male dificiency of kidney sexual impotence, seminal emission premature ejaculation and woman's menoxenia, amenorrhea be infertile.Have nourishing the blood and yin, benefiting QI for activating blood circulation, clear tonifying five ZANG-organs, Yin Yang balancing, QI and blood happy, improve the effect such as body physiological function.
Contain polysaccharide, ucleosides, furan derivative, steroid ferment class, alkaloids, protein, polypeptide, amino acids, triterpenes, sesquiterpene, organic germanium, inorganic salt etc. in the sporophore of Ganoderma, mycelium and the spore.Ganoderan is one of main effective ingredient of Ganoderma, has antitumor, immunomodulating, blood sugar lowering, antioxidation, blood fat reducing and anti-aging effects.Not lower over one hundred kind of the contained triterpenes of Ganoderma, wherein take tetracyclic triterpenes as main, the bitterness of Ganoderma is relevant with contained triterpenes.Triterpenes also is one of effective ingredient of Ganoderma, and human liver cancer cell is had cytotoxicity, also can suppress the release of histamine, has hepatoprotective effect and has anti-allergic effects etc.
Now research of functional oligose is thought and is comprised stachyose, cottonseed sugar, isomaltulose, lactulose, oligofructose, oligomeric xylose, oligomeric galactose, oligomeric isomaltose, iMOS, oligomeric dragon gallbladder sugar, soybean oligo saccharide, oligo-chitosan etc.Be not hydrolyzed the enzyme system of their (except isomaltuloses) in the human body intestinal canal, thereby their not digested absorptions and directly enter large enteral and be preferably bacillus bifidus and utilize, be the multiplicaiton factor of bacillus bifidus.Compare with the oligosaccharide of general (common), functional oligose has unique physiological function: promote bacillus bifidus propagation 1.: functional oligose is the multiplicaiton factor of probiotics in the intestinal, wherein the most obvious propagation to as if bacillus bifidus.Bacillus bifidus is that a kind of endotoxin that neither produces unique in human intestine's flora does not produce again extracellular toxin, the beneficial microbe with many physiological functions of no pathogenicity; 2. low-yield or zero energy: because human body does not possess the enzyme system of decomposition, digestive function oligosaccharide, therefore functional oligose is difficult to be absorbed by human consumption or can not absorb at all, just do not provide energy to the people yet, and some oligosaccharide such as oligofructose, dextrinosan etc. have certain sugariness, can be used as foodstuff base material and in food, use, like sweet food but the needs that can not eat the people (such as diabetes patient, obesity patient etc.) of sweet food to satisfy those; 4. prevent constipation: can stimulate intestinal peristalsis promoting because the bifidobacterium fermentation oligosaccharide produces a large amount of short-chain fatty acid, increase the wettability of feces, and the raised growth by thalline to be keeping certain osmotic pressure, thereby prevent the generation of constipation.Oligosaccharide belongs to water soluble dietary fiber in addition, can promote small intestinal peristalsis, also can prevent and alleviate constipation.
It is mutually auxiliary that Chinese medicine is particular about the monarch and his subjects, reasonable compatibility, drug effect is complementary, so the curative effect of single use a herb is relatively poor, this compatibility have nourishing the blood and yin, benefiting QI for activating blood circulation, clear tonifying five ZANG-organs, Yin Yang balancing, QI and blood happy, improve the effect such as body physiological function; Chinese medicine is particular about whole onset simultaneously, effective ingredient in a herb is wanted combined effect, so guarantee that all effective ingredient can both stripping, because single extracting method and mode are difficult to all effectively strippings of all the components, so single extracting method and mode are to the poor effect of utilizing of Chinese medicine.
For under the condition of not destroying active ingredient, extract to greatest extent effective ingredient whole in the medicine, this extraction process is extracted Alcohol soluble composition and water soluble ingredient in two stages, first in the phase I, utilize 85% edible ethanol and continuously condensation reflux, extract, device effectively extract Alcohol soluble composition, ethanol-soluble extractives is separated with residue, and has effectively improved the permeability of crude drug cell, increase intercellular substance, be beneficial to the extraction of second stage water soluble ingredient.Second stage adds deionized water, behind the crush and grind pulping, extracts water soluble ingredient under boiling water bath and normal pressure in grinder, has kept as much as possible active ingredient and the structure of its crude drug.At last extractum and functional oligose are mixed and made into instant granular, the benefit of the drug effect of rare Chinese medicine and the functional oligose fruit of coming into force is united two into one, being fit to widely, crowd (especially diabetics and obesity patient) takes.
Retrieval contrasts as can be known: the compound Chinese medicinal preparation that contains the Herba Dendrobii raw material of present domestic research and development, its medicament composing prescription, dosage form and preparation technology are different, the compound recipe that patent application of the present invention relates to suddenly the prescription of dry measure used in former times Rong sesame granule and production technology at home there are no bibliographical information, and relate to the compound preparation patent of Herba Dendrobii: application CN201110198864.5, in " a kind of compound dendrobium huoshanense granules and production technology ", the method adopt long High Temperature High Pressure (temperature: 115 ℃--120 ℃, pressure: 0.15MPa-0. 2Mpa, time: method 15-18h) is extracted the water miscible composition of Herba Dendrobii and other compatibility medical material, this certainly will cause loss and the structural change of effective ingredient, and the inventor does not do any analysis and explanation to this predictable consequence.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of compound recipe of filling a hole in the market suddenly dry measure used in former times Rong sesame granule and production technology thereof.This invention has realized the reasonable combination of valuable ingredient of Chinese medicine and functional oligose and development and use, utilization ratio and the effect of Herba Dendrobii, Fructus Mori, Herba Cistanches and Ganoderma have been improved, the benefit of the effect of rare Chinese medicine and the functional oligose fruit of coming into force is united two into one, and being fit to widely, crowd (especially diabetics and obesity patient) takes.
The scheme that the present invention solves the problems of the technologies described above:
A kind of compound recipe is dry measure used in former times Rong sesame granule suddenly, and the part by weight of each raw material is in its prescription: Herba Dendrobii 10%-15%, Fructus Mori 20-25%, Herba Cistanches 5-10%, Ganoderma 5-10%, functional oligose 40-60%.
Preferably, compound recipe suddenly in the prescription of dry measure used in former times Rong sesame granule the part by weight of each raw material be: Herba Dendrobii 15%, Fructus Mori 25%, Herba Cistanches 10%, Ganoderma 10%, functional oligose 40%.
Compound recipe suddenly in the prescription of dry measure used in former times Rong sesame granule the part by weight of each raw material be: Herba Dendrobii 10%, Fructus Mori 20%, Herba Cistanches 5%, Ganoderma 5%, functional oligose 60%.
Compound recipe suddenly in the prescription of dry measure used in former times Rong sesame granule the part by weight of each raw material be: Herba Dendrobii 10%, Fructus Mori 25%, Herba Cistanches 5%, Ganoderma 5%, functional oligose 55%.
It is wherein a kind of that described functional oligose is selected from oligofructose, oligomeric xylose, oligomeric galactose, oligomeric isomaltose, iMOS, oligomeric dragon gallbladder sugar, soybean oligo saccharide.
Compound recipe is the production technology of dry measure used in former times Rong sesame granule suddenly, comprises the steps:
(1) get Herba Dendrobii, Fructus Mori, Herba Cistanches, Ganoderma by formulation ratio, pick remove impurity, clean, spreading for cooling is pulverized, and crosses the 40-50 mesh sieve, and Fructus Mori need not be pulverized;
(2) Herba Dendrobii, Fructus Mori, Herba Cistanches, the Ganoderma rear adding 10-15 that stirs doubly measures 85% edible ethanol, extracting 5-6h in the condensation reflux, extract, device continuously, bath temperature is 98-100 ℃, and the negative pressure concentrated extracting solution is to the thick paste shape, Recycled ethanol keeps filtering residue;
(3) filtering residue in the step (2) adds the deionized water of 10-15 times of weight, in grinder behind the crush and grind pulping, carry 2 times boiling to carry boiling respectively in the device, duration is 3-4h respectively, 2-3h, boil the temperature and pressure of carrying and be respectively boiling water bath and normal pressure, leach cooking liquid filters and merges, and negative pressure is concentrated into paste;
(4) extractum that step (2) and step (3) is obtained merges, more further negative pressure to be concentrated into density be 1.1x10
3-1.2x10
3Kg/m
3
(5) extractum and the functional oligose mixing after will concentrating, granulation, granule can further be distributed into bag or be packaged into capsule.
The condition that described negative pressure satisfies is :-0.07MPa--0.08Mpa.
Advantage of the present invention is:
1,, effectively development and use reasonable to this valuable ingredient of Chinese medicine of Herba Dendrobii have been realized;
2, efficiently solve the low problem of effective ingredient dissolution rate with techniques such as continuous condensing reflux alcohol extraction and crush and grind water extractions, and guaranteed structure and the curative effect of crude drug effective ingredient;
3, be mixed and made into granule with functional oligose behind the concentrated paste that forms of negative pressure, can take on a small quantity at any time, wash wet suit open and use;
4, this invention has effectively been brought into play the efficacy effect of Herba Dendrobii, Fructus Mori, Herba Cistanches and Ganoderma by the compound recipe combination, and test shows that compound preparation is than the high several times of effect of unitary agent.
5, rare Chinese medicine and the compound granulation of functional oligose, strengthened the health care effect, being fit to widely, the people takes.
The specific embodiment
The invention will be further described below in conjunction with embodiment, can be implemented so that those skilled in the art can better understand the present invention also, but illustrated embodiment is not as a limitation of the invention.
Embodiment 1
A kind of compound recipe is dry measure used in former times Rong sesame granule suddenly, and the part by weight of each raw material is in its prescription: Herba Dendrobii 15%, Fructus Mori 25%, Herba Cistanches 10%, Ganoderma 10%, oligofructose 40%.
Compound recipe is the production technology of dry measure used in former times Rong sesame granule suddenly, comprises the steps:
(1) get Herba Dendrobii, Fructus Mori, Herba Cistanches, Ganoderma by formulation ratio, pick remove impurity, clean, spreading for cooling is pulverized, and crosses 40 mesh sieves, and Fructus Mori need not be pulverized;
(2) Herba Dendrobii, Fructus Mori, Herba Cistanches, the Ganoderma edible ethanol of 10 times of rear addings amount 85% that stirs is extracting 5h in the condensation reflux, extract, device continuously, and bath temperature is 98 ℃, the negative pressure concentrated extracting solution is to the thick paste shape, negative pressure is-0.07MPa that Recycled ethanol keeps filtering residue;
(3) filtering residue in the step (2) adds the deionized water of 10 times of weight, in grinder behind the crush and grind pulping, carry 2 times boiling to carry boiling respectively in the device, duration is 3h respectively, 2h boils the temperature and pressure of carrying and is respectively boiling water bath and normal pressure, and leach cooking liquid filters and merges, negative pressure is concentrated into paste, and negative pressure is-0.07MPa;
(4) extractum that step (2) and step (3) is obtained merges, more further negative pressure to be concentrated into density be 1.1x10
3Kg/m
3, negative pressure is-0.07MPa;
(5) extractum and the oligofructose mixing after will concentrating, granulation, granule can further be distributed into bag or be packaged into capsule.
Embodiment 2
A kind of compound recipe is dry measure used in former times Rong sesame granule suddenly, and the part by weight of each raw material is in its prescription: Herba Dendrobii 10%, Fructus Mori 20%, Herba Cistanches 5%, Ganoderma 5%, iMOS 60%.
Compound recipe is the production technology of dry measure used in former times Rong sesame granule suddenly, comprises the steps:
(1) get Herba Dendrobii, Fructus Mori, Herba Cistanches, Ganoderma by formulation ratio, pick remove impurity, clean, spreading for cooling is pulverized, and crosses 45 mesh sieves, and Fructus Mori need not be pulverized;
(2) Herba Dendrobii, Fructus Mori, Herba Cistanches, the Ganoderma edible ethanol of 12 times of rear addings amount 85% that stirs is extracting 5h in the condensation reflux, extract, device continuously, and bath temperature is 100 ℃, the negative pressure concentrated extracting solution is to the thick paste shape, negative pressure is-0.075MPa that Recycled ethanol keeps filtering residue;
(3) filtering residue in the step (2) adds the deionized water of 12 times of weight, in grinder behind the crush and grind pulping, carry 2 times boiling to carry boiling respectively in the device, duration is 4h respectively, 3h boils the temperature and pressure of carrying and is respectively boiling water bath and normal pressure, and leach cooking liquid filters and merges, negative pressure is concentrated into paste, and negative pressure is-0.075MPa;
(4) extractum that step (2) and step (3) is obtained merges, more further negative pressure to be concentrated into density be 1.15x10
3Kg/m
3, negative pressure is-0.075MPa;
(5) extractum and the iMOS mixing after will concentrating, granulation, granule can further be distributed into bag or be packaged into capsule.
Embodiment 3
A kind of compound recipe is dry measure used in former times Rong sesame granule suddenly, and the part by weight of each raw material is in its prescription: Herba Dendrobii 10%, Fructus Mori 25%, Herba Cistanches 5%, Ganoderma 5%, soybean oligo saccharide 55%.
Compound recipe is the production technology of dry measure used in former times Rong sesame granule suddenly, comprises the steps:
(1) get Herba Dendrobii, Fructus Mori, Herba Cistanches, Ganoderma by formulation ratio, pick remove impurity, clean, spreading for cooling is pulverized, and crosses 50 mesh sieves, and Fructus Mori need not be pulverized;
(2) Herba Dendrobii, Fructus Mori, Herba Cistanches, the Ganoderma edible ethanol of 15 times of rear addings amount 85% that stirs is extracting 6h in the condensation reflux, extract, device continuously, and bath temperature is 100 ℃, the negative pressure concentrated extracting solution is to the thick paste shape, negative pressure is-0.08MPa that Recycled ethanol keeps filtering residue;
(3) filtering residue in the step (2) adds the deionized water of 15 times of weight, in grinder behind the crush and grind pulping, carry 2 times boiling to carry boiling respectively in the device, duration is 4h respectively, 3h boils the temperature and pressure of carrying and is respectively boiling water bath and normal pressure, and leach cooking liquid filters and merges, negative pressure is concentrated into paste, and negative pressure is-0.08MPa;
(4) extractum that step (2) and step (3) is obtained merges, more further negative pressure to be concentrated into density be 1.2x10
3Kg/m
3, negative pressure is-0.08MPa;
(5) extractum and the functional oligose mixing after will concentrating, granulation, granule can further be distributed into bag or be packaged into capsule.
Embodiment 4
A kind of compound recipe is dry measure used in former times Rong sesame granule suddenly, and the part by weight of each raw material is in its prescription: Herba Dendrobii 10%, Folium Rehmanniae 10%, leaf of Caulis Sacchari sinensis 10%, Fructus Trichosanthis leaf 5%, Herba Cistanches 5%, Ganoderma 5%, soybean oligo saccharide 55%.
Compound recipe is the production technology of dry measure used in former times Rong sesame granule suddenly, comprises the steps:
(1) get Herba Dendrobii, Folium Rehmanniae, leaf of Caulis Sacchari sinensis, Fructus Trichosanthis leaf, Herba Cistanches, Ganoderma by formulation ratio, pick remove impurity, clean, spreading for cooling is pulverized, and crosses 50 mesh sieves;
(2) Herba Dendrobii, Folium Rehmanniae, leaf of Caulis Sacchari sinensis, Fructus Trichosanthis leaf, Herba Cistanches, the Ganoderma edible ethanol of 15 times of rear addings amount 85% that stirs, extracting 6h in the condensation reflux, extract, device continuously, bath temperature is 100 ℃, the negative pressure concentrated extracting solution is to the thick paste shape, negative pressure is-0.08MPa, Recycled ethanol keeps filtering residue;
(3) filtering residue in the step (2) adds the deionized water of 15 times of weight, in grinder behind the crush and grind pulping, carry 2 times boiling to carry boiling respectively in the device, duration is 4h respectively, 3h boils the temperature and pressure of carrying and is respectively boiling water bath and normal pressure, and leach cooking liquid filters and merges, negative pressure is concentrated into paste, and negative pressure is-0.08MPa;
(4) extractum that step (2) and step (3) is obtained merges, more further negative pressure to be concentrated into density be 1.2x10
3Kg/m
3, negative pressure is-0.08MPa;
(5) extractum and the functional oligose mixing after will concentrating, granulation, granule can further be distributed into bag or be packaged into capsule.
More than fill a prescription, collaborative playing a role strengthened the effect of Herba Dendrobii, can be used for diabetic to take.Every day 20-30 mL.Divide secondary to take.
Case 1:
Lee, man, 53 years old.
Health is tired, loses weight companion's poor appetite, agitation, insomnia, sometimes dry stool.Blood fat when medical: total sterin 7.6 mmol/l triglyceride 3.3 mmol/l, fasting glucose: 13.2mmol/l, blood glucose 16.3 mmol/l are diagnosed as type Ⅱdiabetes mellitus after meal.Cooperate do appropriate exercise every day, give present embodiment after three months again, blood glucose descends to some extent, surveys its fasting glucose 6.5 mmol/l, and 2 hours blood glucoses are 7.8 mmol/l after meal, and follow-up is healed after half a year.
Case 2:
Lee so-and-so, woman, 63 years old.
The headache dreaminess, companion's poor appetite, agitation, appetite increases, and loses weight.Fasting glucose: 10.8mmol/l, after meal blood glucose 15.6mmol/l when medical.Give again present embodiment after two months, blood glucose descends to some extent, and the myasthenia of limbs sense disappears, and surveys its fasting glucose 6.3 mmol/l, 2 hours blood glucoses are 7.6 mmol/l after meal, the suggestion diet should be light, transfers smooth emotion, eats vegetable and fruit more, suitably take exercise, follow-up is healed after half a year, and health is fine so far, glucostasis.
Case 3:
Wu so-and-so, man, 56 years old.
Numb limbs and tense tendons, uncomfortable in chest, headache dreaminess, agitation, insomnia, red and uncoated tongue, deep and stringy pulse.Give present embodiment after three months, blood glucose descends to some extent, surveys its fasting glucose 6.4 mmol/l, and 2 hours blood glucoses are 8.6mmol/l after meal, and follow-up is healed after half a year, and glucostasis, blood fat are normal.
Although more than described the specific embodiment of the present invention; but being familiar with those skilled in the art is to be understood that; our described specific embodiment is illustrative; rather than for the restriction to scope of the present invention; those of ordinary skill in the art are in modification and the variation of the equivalence of doing according to spirit of the present invention, all should be encompassed in the scope that claim of the present invention protects.
Claims (7)
1. compound recipe dry measure used in former times Rong sesame granule suddenly, it is characterized in that: the part by weight of each raw material is in its prescription: Herba Dendrobii 10-15%, Fructus Mori 20-25%, Herba Cistanches 5-10%, Ganoderma 5-10%, functional oligose 40-60%.
2. a kind of compound recipe according to claim 1 dry measure used in former times Rong sesame granule suddenly is characterized in that: described compound recipe suddenly in the prescription of dry measure used in former times Rong sesame granule the part by weight of each raw material be: Herba Dendrobii 15%, Fructus Mori 25%, Herba Cistanches 10%, Ganoderma 10%, functional oligose 40%.
3. a kind of compound recipe according to claim 1 dry measure used in former times Rong sesame granule suddenly is characterized in that: described compound recipe suddenly in the prescription of dry measure used in former times Rong sesame granule the part by weight of each raw material be: Herba Dendrobii 10%, Fructus Mori 20%, Herba Cistanches 5%, Ganoderma 5%, functional oligose 60%.
4. a kind of compound recipe according to claim 1 dry measure used in former times Rong sesame granule suddenly is characterized in that: described compound recipe suddenly in the prescription of dry measure used in former times Rong sesame granule the part by weight of each raw material be: Herba Dendrobii 10%, Fructus Mori 25%, Herba Cistanches 5%, Ganoderma 5%, functional oligose 55%.
5. the dry measure used in former times Rong sesame granule suddenly of a kind of compound recipe described in according to claim 1, it is characterized in that: it is wherein a kind of that described functional oligose is selected from oligofructose, oligomeric xylose, oligomeric galactose, oligomeric isomaltose, iMOS, oligomeric dragon gallbladder sugar, soybean oligo saccharide.
6. a compound recipe as claimed in claim 1 production technology of dry measure used in former times Rong sesame granule suddenly is characterized in that comprising the steps:
(1) get Herba Dendrobii, Fructus Mori, Herba Cistanches, Ganoderma by formulation ratio, pick remove impurity, clean, spreading for cooling is pulverized, and crosses the 40-50 mesh sieve, and Fructus Mori need not be pulverized;
(2) Herba Dendrobii, Fructus Mori, Herba Cistanches, the Ganoderma rear adding 10-15 that stirs doubly measures 85% edible ethanol, extracting 5-6h in the condensation reflux, extract, device continuously, bath temperature is 98-100 ℃, and the negative pressure concentrated extracting solution is to the thick paste shape, Recycled ethanol keeps filtering residue;
(3) filtering residue in the step (2) adds the deionized water of 10-15 times of weight, in grinder behind the crush and grind pulping, carry 2 times boiling to carry boiling respectively in the device, duration is 3-4h respectively, 2-3h, boil the temperature and pressure of carrying and be respectively boiling water bath and normal pressure, leach cooking liquid filters and merges, and negative pressure is concentrated into paste;
(4) extractum that step (2) and step (3) is obtained merges, more further negative pressure to be concentrated into density be 1.1x10
3-1.2x10
3Kg/m
3
(5) extractum and the functional oligose mixing after will concentrating, granulation, granule can further be distributed into bag or be packaged into capsule.
A kind of compound recipe described in according to claim 6 suddenly dry measure used in former times Rong sesame granule production technology, it is characterized in that: the condition that described negative pressure satisfies is :-0.07MPa--0.08Mpa.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210582512.4A CN103055157B (en) | 2012-12-28 | 2012-12-28 | Compound dendrobium huoshanense, cistanche and ganoderma granules and production process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210582512.4A CN103055157B (en) | 2012-12-28 | 2012-12-28 | Compound dendrobium huoshanense, cistanche and ganoderma granules and production process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103055157A true CN103055157A (en) | 2013-04-24 |
| CN103055157B CN103055157B (en) | 2015-04-01 |
Family
ID=48098252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210582512.4A Active CN103055157B (en) | 2012-12-28 | 2012-12-28 | Compound dendrobium huoshanense, cistanche and ganoderma granules and production process thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103055157B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104126747A (en) * | 2014-07-14 | 2014-11-05 | 赵亮 | Polymer functional sugar and food composition and preparation methods thereof |
| CN104799271A (en) * | 2014-01-26 | 2015-07-29 | 段胜保 | Sexual function health product |
| CN105533743A (en) * | 2015-12-31 | 2016-05-04 | 广西扬桂生物科技有限公司 | Dendrobium officinale instant powder |
| CN105533744A (en) * | 2015-12-31 | 2016-05-04 | 广西扬桂生物科技有限公司 | Dendrobium officinale instant powder |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101371902A (en) * | 2008-08-22 | 2009-02-25 | 浙江省医学科学院 | Effect of natural active glycogen for reducing blood sugar and blood fat |
| CN102266490A (en) * | 2011-07-15 | 2011-12-07 | 安徽圣农生物科技股份有限公司 | Formula of compound dendrobium huoshanense granules and production method |
-
2012
- 2012-12-28 CN CN201210582512.4A patent/CN103055157B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101371902A (en) * | 2008-08-22 | 2009-02-25 | 浙江省医学科学院 | Effect of natural active glycogen for reducing blood sugar and blood fat |
| CN102266490A (en) * | 2011-07-15 | 2011-12-07 | 安徽圣农生物科技股份有限公司 | Formula of compound dendrobium huoshanense granules and production method |
Non-Patent Citations (4)
| Title |
|---|
| 冯敏: "《东方神奇仙草：现代科学论灵芝》", 31 May 2005, 科学出版社 * |
| 季宇彬: "《复方中药药理与应用》", 31 October 2005, 中国医药科技出版社 * |
| 戎志梅: "《生物化工新产品与新技术开发指南》", 30 April 2004, 化学工业出版社 * |
| 马力行: "中医药治疗糖尿病（消渴病）研究进展", 《中医临床研究》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104799271A (en) * | 2014-01-26 | 2015-07-29 | 段胜保 | Sexual function health product |
| CN104126747A (en) * | 2014-07-14 | 2014-11-05 | 赵亮 | Polymer functional sugar and food composition and preparation methods thereof |
| CN105533743A (en) * | 2015-12-31 | 2016-05-04 | 广西扬桂生物科技有限公司 | Dendrobium officinale instant powder |
| CN105533744A (en) * | 2015-12-31 | 2016-05-04 | 广西扬桂生物科技有限公司 | Dendrobium officinale instant powder |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103055157B (en) | 2015-04-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103103099B (en) | A kind of compound Dendrobium huoshanense-cistanchganoderma ganoderma health promoting wine and production technology | |
| CN102511869B (en) | Thickened red jujube ginger pulp | |
| CN104940606A (en) | Deer-horn gelatin health product for conditioning eight types of abnormal body constitution | |
| CN102784363B (en) | Traditional Chinese medicine composition for treating pancreatic cancer and preparation method thereof | |
| CN103493941A (en) | Weight-reducing and health-protecting tea and preparation method thereof | |
| CN105901715A (en) | Deer glue cake and making method thereof | |
| CN105942498A (en) | Functional nutritional food compounds with diabetes-treating effects and preparation methods thereof | |
| CN101612315A (en) | A kind of compound Chinese medicinal preparation that is used to adjust function of human body | |
| CN103168883A (en) | Pathogenic microorganism preventing antiviral tea beverage granules capable of boosting immunity and preparation method thereof | |
| CN104904964A (en) | Folium apocyni veneti health tea capable of decreasing sugar and lipid and preparation method thereof | |
| CN102114218B (en) | Traditional Chinese medicine for tonifying kidney, strengthening yang and resisting fatigue and preparation method thereof | |
| CN107865181A (en) | Chinese medicine ferment pressed candy and preparation method thereof | |
| CN103099833A (en) | Soft capsule helpful for relieving sports fatigue and delaying aging and preparation method thereof | |
| CN103055157B (en) | Compound dendrobium huoshanense, cistanche and ganoderma granules and production process thereof | |
| CN102188658A (en) | Chinese medicine preparation for treating essence and blood deficiency for kidney-yin deficiency patients, preparation method thereof and application thereof | |
| CN107751993A (en) | A kind of antifatigue cream taste and preparation method thereof | |
| CN101946895A (en) | Functional food taking loach as main material and preparation method thereof | |
| CN103191308A (en) | Compound Dendrobium huoshanense-cistanche-glossy ganoderma buccal tablet and production process thereof | |
| CN101011562A (en) | Novel formulation of shenqiwendan decoction and production method thereof | |
| CN102349950B (en) | Food, health product or pharmaceutical composition as well as preparation method and application thereof | |
| CN104544084B (en) | A kind of health food for diabetics | |
| CN103734767A (en) | Health-care food | |
| CN105994740A (en) | Green tea with dendrobium officinale and method for preparing green tea | |
| CN102511876A (en) | Hawthorn red jujube thick syrup | |
| CN102266511A (en) | Chewable tablet for removing summer heat and strengthening stomach for children, and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: ANHUI TONGJISHENG BIOTECHNOLOGY CO., LTD. Free format text: FORMER NAME: LU AN TONGJISHENG BIOTECHNOLOGY CO., LTD. |
|
| CP01 | Change in the name or title of a patent holder |
Address after: 237000 Anhui city of Lu'an province through three road and road intersection and Gao city science and Technology Bureau Business Service Center Patentee after: Lu'an TongJiSheng Biotechnology Co., Ltd. Address before: 237000 Anhui city of Lu'an province through three road and road intersection and Gao city science and Technology Bureau Business Service Center Patentee before: Lu'an TongJiSheng Biotechnology Co., Ltd. |