CN103041230B - Traditional Chinese medicine composition for treating protrusion of lumbar intervertebral disc and preparation method of composition - Google Patents
Traditional Chinese medicine composition for treating protrusion of lumbar intervertebral disc and preparation method of composition Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating protrusion of lumbar intervertebral disc and a preparation method of the composition. The active ingredients of the traditional Chinese medicine composition is prepared from the following materials in parts by weight: 20-30 parts of prepared rehmannia roots, 5-15 parts of dendrobe, 20-30 parts of white paeony roots, 5-15 parts of achyranthes bidentata, 1-5 parts of cinnamon, 6-10 parts of corydalis tubers, 5-15 parts of beautiful sweetgum fruits, 6-10 parts of rheum officinale, 4-8 parts of garter snakes, 4-8 parts of earthworms, 5-15 parts of monkshoods, 4-8 parts of cortex acanthopanacis, 20-30 parts of coix seeds, 5-15 parts of rhizoma cyper and 4-8 parts of liquorices. The active ingredients of the chine are prepared into decoction, tablets, water-honeyed pills, capsules, powder, paste, oral liquid and granules. The traditional Chinese medicine composition disclosed by the invention is pure traditional Chinese medicine preparation, free of any toxic and side effect to a patient, convenient to use and low in cost. Moreover, the total effective rate for treating protrusion of lumbar intervertebral disc is more than 95%.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc and preparation method thereof.
Background technology
Prolapse of lumbar intervertebral disc is to cause the modal disease of chronic low-back pain, accounts for chronic low-back pain morbidity patient's 30%.Lumbar intervertebral disc protrusion tissue stimulates nerve root machinery, chemistry and autoimmune, is the generally acknowledged pathogeny of prolapse of lumbar intervertebral disc, and wherein mechanical pressure is main paathogenic factor.Under this theory impact, emerge the numerous art formulas taking Nuclectomy as main contents, but increasing material confirmation, the late result of Surgical treatment of lumbar intervertebral disc herniation is not better than conventional non-operative treatment.Non-operative treatment can be preserved the integrity of waist anatomical structure and functional activity to greatest extent, also can make most patients' symptom be eased and for a long time in steady statue, is the first-selected therapy of prolapse of lumbar intervertebral disc.Non-surgical treatment is various, and as maneuver, traction, acupuncture, physical therapy and Drug therapy etc., wherein manual reduction is representative therapy, but treatment cost is high, and the dispute for the treatment of mechanism is larger, although obtained certain clinical effectiveness, also cause the many secondary damage including paraplegia simultaneously.Herbal treatment is the Therapeutic Method that compatriots gladly accept, research to asymptomatic type prolapse of lumbar intervertebral disc in recent years, and basis, clinical research prove in a large number, when normal nerve compression, there is no pain, while only having inflammation nerve compression, just cause pain, to stimulate the aseptic inflammation causing be the direct inducement of prolapse of lumbar intervertebral disc for chemistry, autoimmune.This is just for treatment by Chinese herbs prolapse of lumbar intervertebral disc provides clue.The traditional Chinese medical science thinks that people gradually loses to middle aged kidney qi, waist knee joint lower limb foot lose its moisten foster, " not Rong Ze pain ".Caused by liver and kidney deficiency, is the exopathogen such as the basis of lumbago morbidity, multiple wind-engaging cold-damp, and tumbling down damage etc. cause QI-blood circulation lose smooth, " stagnation of QI and blood may bring about pain ".According to the Therapeutic Principle of " actually clear profit, void is tonification ", for the treatment of this disease taking " logical method " and " reinforcement " as main.But only there is clinically deficient syndrome or only being invaded by exogenous pathogen person is more rare, and comparatively common with simulataneous insufficiency and excessive, therefore the Therapeutic Method that uses " through-supplementation " more.
Summary of the invention
The technical problem to be solved in the present invention is to provide Chinese medicine composition of a kind of good effect, cure rate is high and expense is low treatment prolapse of lumbar intervertebral disc and preparation method thereof.
For solving the problems of the technologies described above, raw material composition and the weight proportion thereof of effective ingredient of the present invention are: 20～30 parts of Radix Rehmanniae Preparata, 5～15 parts of Herba Dendrobiis, 20～30 parts of the Radix Paeoniae Albas, 5～15 parts of Radix Achyranthis Bidentataes, 1～5 part of Cortex Cinnamomi, 6～10 parts of Rhizoma Corydalis, 5～15 parts of Fructus Liquidambaris, 6～10 parts of Radix Et Rhizoma Rhei, 4～8 parts of Zaocyss, 4～8 parts of Pheretimas, 5～15 parts of Radix Aconiti Lateralis Preparatas, 4～8 parts of Cortex Acanthopanciss, 20～30 parts of Semen Coiciss, 5～15 parts of Rhizoma Cyperis, 4～8 parts, Radix Glycyrrhizae.
Raw material composition and the weight proportion thereof of preferably making this effective ingredient are: 23～27 parts of Radix Rehmanniae Preparata, 8～12 parts of Herba Dendrobiis, 23～27 parts of the Radix Paeoniae Albas, 8～12 parts of Radix Achyranthis Bidentataes, 2～4 parts of Cortex Cinnamomis, 7～9 parts of Rhizoma Corydalis, 8～12 parts of Fructus Liquidambaris, 7～9 parts of Radix Et Rhizoma Rhei, 5～7 parts of Zaocyss, 5～7 parts of Pheretimas, 8～12 parts of Radix Aconiti Lateralis Preparatas, 5～7 parts of Cortex Acanthopanciss, 23～27 parts of Semen Coiciss, 8～12 parts of Rhizoma Cyperis, 5～7 parts, Radix Glycyrrhizae.
Raw material composition and the weight proportion thereof of further preferably making this effective ingredient are: 24～26 parts of Radix Rehmanniae Preparata, 9～11 parts of Herba Dendrobiis, 24～26 parts of the Radix Paeoniae Albas, 9～11 parts of Radix Achyranthis Bidentataes, 2～4 parts of Cortex Cinnamomis, 7～9 parts of Rhizoma Corydalis, 9～11 parts of Fructus Liquidambaris, 7～9 parts of Radix Et Rhizoma Rhei, 5～7 parts of Zaocyss, 5～7 parts of Pheretimas, 9～11 parts of Radix Aconiti Lateralis Preparatas, 5～7 parts of Cortex Acanthopanciss, 24～26 parts of Semen Coiciss, 9～11 parts of Rhizoma Cyperis, 5～7 parts, Radix Glycyrrhizae.
Raw material composition and the weight proportion thereof of more preferably making this effective ingredient are: 25 parts of Radix Rehmanniae Preparata, 10 parts of Herba Dendrobiis, 25 parts of the Radix Paeoniae Albas, 10 parts of Radix Achyranthis Bidentataes, 3 parts of Cortex Cinnamomis, 8 parts of Rhizoma Corydalis, 10 parts of Fructus Liquidambaris, 8 parts of Radix Et Rhizoma Rhei, 6 parts of Zaocyss, 6 parts of Pheretimas, Radix Aconiti Lateralis Preparata 10g part, 6 parts of Cortex Acanthopanciss, 25 parts of Semen Coiciss, 10 parts of Rhizoma Cyperis, 6 parts, Radix Glycyrrhizae.
Preparation method of the present invention comprises the following steps:
A, dry crude drug is crushed to 100～120 orders, and mix homogeneously, in general ball pot, sprays water smoke, a small amount of medicated powder of spreading makes it to mix with water smoke, rotates general ball pot, and the brush medicated powder that wall adheres to of cooking makes medicated powder granule;
B, again to spraying mulse in the medicated powder granule in general ball pot and pot, the powder that spreads pesticides, rotate general ball pot, so iterative cycles is until by the general medicated powder spheroidal particle of making 0.8～1 millimeter of particle diameter of diameter, obtain ball mould;
C, the ball mould obtaining is rotated in general ball pot, on ball mould, with mulse moistening ball mould, the powder that spreads pesticides, repeatedly carry out, until molding reaches finished product water-honeyed pill prescribed level standard, final drying, collection, subpackage.
The every 100g medicated powder of described molding water-honeyed pill refined honey used is 20～40g.
Mel in described mulse and the part by weight of water are: 1:3～1:4.
The diameter of described finished product water-honeyed pill is 3～4 millimeters.
The raw material of described effective ingredient is prepared into water decoction, tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
In formula of the present invention, Radix Rehmanniae Preparata, sweet, temperature, enters Liver and kidney and the special nourishing the blood and yin of merit, and life essence-filling, marrow-benefitting has the inhibitory action of antagonism dexamethasone to Pituitary Adrenal cortex system, and can promote the synthetic of adrenocortical hormone.Herba Dendrobii, sweet, be slightly cold, return stomach, kidney channel.Shennong's Herbal is called its " strong foot knee joint, drives cold numbness for beneficial smart reinforcing YIN-essence, strong muscle tonify deficiency ".Herba Dendrobii both can nourishing kidney yin, can alleviate again the dry property of dispelling wind and removing obstruction in the collateral medicine.The Radix Paeoniae Alba, bitter, sour, be slightly cold, return liver, spleen channel.Nourish blood and seek, relieving spasm to stop pain.Its main chemical compositions has peoniflorin, paeonol, peonin etc., and the writhing response that Radix Paeoniae Alba extract Dichlorodiphenyl Acetate causes has obvious analgesic effect, share with the methanol complex of Radix Glycyrrhizae, and the two Dichlorodiphenyl Acetate writhing response has synergic antalgic effect.Peoniflorin has good spasmolysis, with Radix Glycyrrhizae 5 relieving spasm to stop pain mutually.Radix Achyranthis Bidentatae, bitter, sweet, sour, flat, return liver, kidney channel.Promoting blood circulation to restore menstrual flow, invigorating the liver and kidney, bone and muscle strengthening.There is antiinflammatory, analgesic activity, can improve body's immunity.Cortex Cinnamomi, pungent, sweet, hot greatly, return kidney, spleen, the heart, Liver Channel.Dispersing cold for relieving pain, warming the meridian and promoting blood circulation.In Cortex Cinnamomi, containing volatile oil (Oleum Cinnamomi), main component is cinnamic aldehyde, cinnamyl alcohol, cinnamyl alcohol acetate, cinnamic acid etc., has blood vessel dilating, blood circulation promoting, enhancing arteria coronaria and cerebral blood flow, makes degradation effect under vascular resistance; Oleum Cinnamomi, cinnamic aldehyde, cinnamic acid have the effects such as calmness, analgesia, antipyretic, convulsion.Rhizoma Corydalis, pungent, bitter, temperature, GUIXIN, liver, spleen channel.Invigorate blood circulation, circulation of qi promoting, pain relieving, " stagnation of QI in promoting the circulation of blood, stasis in gas, therefore can specially control upper and lower all pains all over the body ".Mainly contain alkaloid more than 20 and plant, mainly contain corydalis A,B,C,D, heptan element, Xin Su, ninth of the ten Heavenly Stems element, third of the twelve Earthly Branches element, ugly element, son element etc.Tetrahydropalmatine has significant analgesia, hypnosis, calm and stable effect, and the analgesic activity of first element and ugly element is also comparatively obvious, and second is plain and uglyly have an effect of flaccid muscles.Fructus Liquidambaris, hardship, flat, return liver, kidney channel.Eradicates wind is active, and diuretic stimulates the menstrual flow, and it " can lead to acupoints of twelve meridians greatly ".To albumen arthritis, swelling has inhibitory action to Fructus Liquidambaris.Radix Et Rhizoma Rhei, hardship, cold, return spleen, stomach, large intestine, liver, pericardium channel.Heat and toxic materials clearing away, eliminating blood stasis and inducing menstruation.There is antiinflammatory antipyretic, and immunoloregulation function.Zaocys, sweet, flat, return Liver Channel.This moral character is walked to alter, and can search ailment said due to cold or exposure, joint thoroughly, and the meridian dredging, is usually used in rheumatism arthromyodynia and apoplexy and hemiplegia, is especially suitable for rheumatoid arthritis stubborn.Zaocys decocting liquid and alcohol extract have antiinflammatory, calmness, analgesic activity.Pheretima, salty, cold, return liver, spleen, urinary bladder channel.Dredging collateral, diuresis.Extract all has calmness, anticonvulsant action to mice and rabbit; Pheretima also has immune, antibacterial, the diuresis of enhancing.Radix Aconiti Lateralis Preparata, pungent, sweet, hot greatly, poisonous, GUIXIN, kidney, spleen channel.Mend fire supporing yang, dispersing cold for relieving pain.Its gas is male brave, walks and does not keep, can promoting the flow of QI in the collateral by warming the meridian, by wind-cold damp pathogen in meridians, there is stronger dispersing cold for relieving pain effect.Radix Aconiti Lateralis Preparata has significant antiinflammatory action, can suppress rat paw edema due to Ovum Gallus domesticus album, carrageenin, formaldehyde etc., suppresses due to acetic acid capillary permeability hyperfunction, suppresses Granuloma formation and adjuvant-induced arthritis; Mesaconitine, aconitine and hypaconitine all have analgesic activity.Study and show recently, Radix Aconiti Lateralis Preparata energy enhancing body oxidation resistance, has anti-aging effects.Cortex Acanthopancis, pungent, bitter, temperature, returns liver, kidney channel.Eradicates rheumatism, invigorating the liver and kidney, bone and muscle strengthening, diuretic.The pungent energy of the Cortex Acanthopancis wind that falls apart, bitter can dampness, temperature is can Eradicates cold, and the merit of double tonification, is robustness Eradicates medicine for rheumatism, is especially suitable for old man and weakness due to chronic disease person.Cortex Acanthopancis has antiinflammatory, analgesia, sedation, can improve the concentration of serum antibody, the phagocytic function of promotion mononuclear phagocyte, has anti-stress effect, gonadotropic Effect, and energy antimutagenic, and antiulcer, and have certain immunologic rejection effect.Semen Coicis, sweet, light, cool, return spleen, stomach, lung meridian.Eliminating dampness by diuresis, spleen invigorating, eliminating impediment.Its fatty oil has antipyretic, calm, analgesic activity.Rhizoma Cyperi, pungent, micro-hardship, micro-sweet, flat, return liver, spleen, tri-jiao channel.Removing obstruction in the collateral to relieve pain, regulating the flow of Qi and the middle Jiao.Compendium of Material Medica thinks that it " stops trusted subordinate, limbs, head, order, tooth, all pains of ear ".This product, containing volatile oil, mainly contains the effects such as analgesia, antiinflammatory.Its circulation of qi promoting to be to help blood, and in so as not to warm-dryness syndrome medicine injure one's stomach.Radix Glycyrrhizae, sweet, flat, GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Radix Glycyrrhizae has antiinflammatory, antiallergic, and diuresis, blood fat reducing, the effect such as protects the liver.The product of the many warm-dryness syndrome of this group Chinese medicine, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, makes righting and does not stay heresy, gets rid of evils and does not just hinder.
The present invention had both sincerely abided by the principle of the traditional Chinese medical science " through-supplementation ", again according to modern medicine newest research results, choose and there is anti-inflammatory analgetic, the Chinese medicine that improves the effects such as blood circulation suits the pathomechanism of prolapse of lumbar intervertebral disc, above Chinese medicine cooperatively interacts and plays altogether the effect of invigorating the liver and kidney, the meridian dredging, stopping numbness pain, meets the principle of the traditional Chinese medical science " through-supplementation "; Through screening meticulously, said medicine again more has anti-inflammatory analgetic, improves the effects such as blood circulation, suits the pathomechanism of prolapse of lumbar intervertebral disc, is " Chinese and Western is taken into account ".Medicine can synergism, produces good therapeutic effect; And extract oral dosage form meets compatriots' medication custom, and patient is acceptant, has both alleviated patient's misery, because drug price is cheap, without any side effects to patient, easy to use again.
Detailed description of the invention
Embodiment 1
Weigh 300 grams of Radix Rehmanniae Preparata, 150 grams of Herba Dendrobiis, 300 grams of the Radix Paeoniae Albas, 150 grams of Radix Achyranthis Bidentataes, 50 grams of Cortex Cinnamomis, 100 grams of Rhizoma Corydalis, 150 grams of Fructus Liquidambaris, 100 grams of Radix Et Rhizoma Rhei, 80 grams of Zaocyss, 80 grams of Pheretimas, 150 grams of Radix Aconiti Lateralis Preparatas, 80 grams of Cortex Acanthopanciss, 300 grams of Semen Coiciss, 150 grams of Rhizoma Cyperis, 80 grams, Radix Glycyrrhizae, adopt existing conventional method to make tablet oral, every is 0.5g containing former dose, everyone is each serving with 10, every day 3 times.
Embodiment 2
Weigh 270 grams of Radix Rehmanniae Preparata, 120 grams of Herba Dendrobiis, 270 grams of the Radix Paeoniae Albas, 120 grams of Radix Achyranthis Bidentataes, 40 grams of Cortex Cinnamomis, 90 grams of Rhizoma Corydalis, 120 grams of Fructus Liquidambaris, 90 grams of Radix Et Rhizoma Rhei, 70 grams of Zaocyss, 70 grams of Pheretimas, 120 grams of Radix Aconiti Lateralis Preparatas, 70 grams of Cortex Acanthopanciss, 270 grams of Semen Coiciss, 120 grams of Rhizoma Cyperis, 70 grams, Radix Glycyrrhizae, said medicine made to water-honeyed pill in accordance with the following methods:
Dry crude drug is crushed to 100～120 orders, and mix homogeneously, in general ball pot, spray water smoke, the a small amount of medicated powder of spreading makes it to mix with water smoke, rotate general ball pot, brush the medicated powder granule that the wall of cooking adheres to, in the medicated powder granule in general ball pot and pot, spray mulse again, powder spreads pesticides, rotate general ball pot, so iterative cycles is until by the general medicated powder spheroidal particle of making 0.8～1 millimeter of particle diameter of diameter, obtain ball mould, the ball mould obtaining is placed in to general ball pot to rotate, on ball mould with mulse moistening ball mould, powder spreads pesticides, repeatedly carry out, until molding reaches the standard-required of diameter 3～4 millimeter pills, the every 100g medicated powder of molding water-honeyed pill refined honey used is 20～40g, mulse is the mixed liquor of Mel and water, Mel wherein and the part by weight of water are: 1:3～1:4, final drying, collect, subpackage.By above-mentioned finished product, for patient, everyone is each serving with 12, every day 3 times.
Embodiment 3
Weigh 260 grams of Radix Rehmanniae Preparata, 110 grams of Herba Dendrobiis, 260 grams of the Radix Paeoniae Albas, 110 grams of Radix Achyranthis Bidentataes, 40 grams of Cortex Cinnamomis, 90 grams of Rhizoma Corydalis, 110 grams of Fructus Liquidambaris, 90 grams of Radix Et Rhizoma Rhei, 70 grams of Zaocyss, 70 grams of Pheretimas, 110 grams of Radix Aconiti Lateralis Preparatas, 70 grams of Cortex Acanthopanciss, 260 grams of Semen Coiciss, 110 grams of Rhizoma Cyperis, 70 grams, Radix Glycyrrhizae, adopt existing conventional method to make capsule oral, every capsules is containing the about 1g of former dose, everyone is each serving with 5, every day 3 times.
Embodiment 4
Weigh 240 grams of Radix Rehmanniae Preparata, 90 grams of Herba Dendrobiis, 240 grams of the Radix Paeoniae Albas, 90 grams of Radix Achyranthis Bidentataes, 20 grams of Cortex Cinnamomis, 70 grams of Rhizoma Corydalis, 90 grams of Fructus Liquidambaris, 70 grams of Radix Et Rhizoma Rhei, 50 grams of Zaocyss, 50 grams of Pheretimas, 90 grams of Radix Aconiti Lateralis Preparatas, 50 grams of Cortex Acanthopanciss, 240 grams of Semen Coiciss, 90 grams of Rhizoma Cyperis, 50 grams, Radix Glycyrrhizae, above-mentioned raw materials medicine crushed after being dried is become to 120 order fine powders, after conventional ripening sterilizing, make powder, everyone is each serving using 6g, every day 3 times.
Embodiment 5
Weigh 200 grams of Radix Rehmanniae Preparata, 50 grams of Herba Dendrobiis, 200 grams of the Radix Paeoniae Albas, 50 grams of Radix Achyranthis Bidentataes, 10 grams of Cortex Cinnamomis, 60 grams of Rhizoma Corydalis, 50 grams of Fructus Liquidambaris, 60 grams of Radix Et Rhizoma Rhei, 40 grams of Zaocyss, 40 grams of Pheretimas, 50 grams of Radix Aconiti Lateralis Preparatas, 40 grams of Cortex Acanthopanciss, 200 grams of Semen Coiciss, 50 grams of Rhizoma Cyperis, 40 grams, Radix Glycyrrhizae, adopt existing conventional method to make unguentum, everyone is each serving containing the about 5g of former dose, every day 3 times in use unguentum.
Embodiment 6
Weigh 250 grams of Radix Rehmanniae Preparata, 100 grams of Herba Dendrobiis, 250 grams of the Radix Paeoniae Albas, 100 grams of Radix Achyranthis Bidentataes, 30 grams of Cortex Cinnamomis, 80 grams of Rhizoma Corydalis, 100 grams of Fructus Liquidambaris, 80 grams of Radix Et Rhizoma Rhei, 60 grams of Zaocyss, 60 grams of Pheretimas, 100 grams of Radix Aconiti Lateralis Preparatas, 60 grams of Cortex Acanthopanciss, 250 grams of Semen Coiciss, 100 grams of Rhizoma Cyperis, 60 grams, Radix Glycyrrhizae, adopt existing conventional method to make oral liquid for oral administration, every oral liquid medicine equivalent is 6g, everyone is each serving with 1, every day 3 times.
Embodiment 7
Weigh 230 grams of Radix Rehmanniae Preparata, 80 grams of Herba Dendrobiis, 230 grams of the Radix Paeoniae Albas, 80 grams of Radix Achyranthis Bidentataes, 20 grams of Cortex Cinnamomis, 70 grams of Rhizoma Corydalis, 80 grams of Fructus Liquidambaris, 70 grams of Radix Et Rhizoma Rhei, 50 grams of Zaocyss, 50 grams of Pheretimas, 80 grams of Radix Aconiti Lateralis Preparatas, 50 grams of Cortex Acanthopanciss, 230 grams of Semen Coiciss, 80 grams of Rhizoma Cyperis, 50 grams, Radix Glycyrrhizae, adopt the agent of existing conventional method granulation for oral administration, everyone is each serving using 5g, every day 3 times.
Embodiment 8
Weigh 25 grams of Radix Rehmanniae Preparata, 10 grams of Herba Dendrobiis, 25 grams of the Radix Paeoniae Albas, 10 grams of Radix Achyranthis Bidentataes, 3 grams of Cortex Cinnamomis, 8 grams of Rhizoma Corydalis, 10 grams of Fructus Liquidambaris, 8 grams of Radix Et Rhizoma Rhei, 6 grams of Zaocyss, 6 grams of Pheretimas, 10 grams of Radix Aconiti Lateralis Preparatas, 6 grams of Cortex Acanthopanciss, 25 grams of Semen Coiciss, 10 grams of Rhizoma Cyperis, 6 grams, Radix Glycyrrhizae, adopt existing conventional method decocting oral, 1 dose of every day, serve on 15～20.
Above embodiment is only for to effect further instruction of the present invention, and scope of the present invention is not subject to the limitation of illustrated embodiment.
Clinical test results is as follows:
Clinical observation patient 145 examples, wherein male 69 examples, female's 76 examples, in reference " traditional Chinese medical science disease Standardization of diagnosis and curative effect " (ZY/T001.1-94), the 103rd diagnosis basis about prolapse of lumbar intervertebral disc of orthopedics and traumatology of Chinese medicine disease Standardization of diagnosis and curative effect assert disease, meets prolapse of lumbar intervertebral disc.With reference to visual analogue scales (Visual Analogus Scale, VAS) evaluation patient pain situation, be 6.69 ± 1.22, with reference to JOA lumbago illness efficacy assessment standard evaluation patient's lumbar function, be 10.50 ± 1.23.Medication treatment after 15～20 days VAS be 1.94 ± 1.11, JOA is 22.41 ± 1.00, in reference " traditional Chinese medical science disease Standardization of diagnosis and curative effect " (ZY/T001.1-94), the 103rd efficacy assessment standard about prolapse of lumbar intervertebral disc of orthopedics and traumatology of Chinese medicine disease Standardization of diagnosis and curative effect carries out curative effect statistics, treat after 15～20 days, result is cured 75 examples, 63 examples that take a turn for the better, 7 examples more, total effective rate 95.17%.
By above-mentioned clinical verification, illustrate that therapeutic effect of the present invention is good, effective percentage is high.
Claims (8)
1. treat a Chinese medicine composition for prolapse of lumbar intervertebral disc, it is characterized in that raw material composition and the weight proportion thereof of making this effective ingredient are: 20～30 parts of Radix Rehmanniae Preparata, 5～15 parts of Herba Dendrobiis, 20～30 parts of the Radix Paeoniae Albas, 5～15 parts of Radix Achyranthis Bidentataes, 1～5 part of Cortex Cinnamomi, 6～10 parts of Rhizoma Corydalis, 5～15 parts of Fructus Liquidambaris, 6～10 parts of Radix Et Rhizoma Rhei, 4～8 parts of Zaocyss, 4～8 parts of Pheretimas, 5～15 parts of Radix Aconiti Lateralis Preparatas, 4～8 parts of Cortex Acanthopanciss, 20～30 parts of Semen Coiciss, 5～15 parts of Rhizoma Cyperis, 4～8 parts, Radix Glycyrrhizae.
2. the Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that raw material composition and the weight proportion thereof of making this effective ingredient are: 23～27 parts of Radix Rehmanniae Preparata, 8～12 parts of Herba Dendrobiis, 23～27 parts of the Radix Paeoniae Albas, 8～12 parts of Radix Achyranthis Bidentataes, 2～4 parts of Cortex Cinnamomis, 7～9 parts of Rhizoma Corydalis, 8～12 parts of Fructus Liquidambaris, 7～9 parts of Radix Et Rhizoma Rhei, 5～7 parts of Zaocyss, 5～7 parts of Pheretimas, 8～12 parts of Radix Aconiti Lateralis Preparatas, 5～7 parts of Cortex Acanthopanciss, 23～27 parts of Semen Coiciss, 8～12 parts of Rhizoma Cyperis, 5～7 parts, Radix Glycyrrhizae.
3. the Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that raw material composition and the weight proportion thereof of making this effective ingredient are: 24～26 parts of Radix Rehmanniae Preparata, 9～11 parts of Herba Dendrobiis, 24～26 parts of the Radix Paeoniae Albas, 9～11 parts of Radix Achyranthis Bidentataes, 2～4 parts of Cortex Cinnamomis, 7～9 parts of Rhizoma Corydalis, 9～11 parts of Fructus Liquidambaris, 7～9 parts of Radix Et Rhizoma Rhei, 5～7 parts of Zaocyss, 5～7 parts of Pheretimas, 9～11 parts of Radix Aconiti Lateralis Preparatas, 5～7 parts of Cortex Acanthopanciss, 24～26 parts of Semen Coiciss, 9～11 parts of Rhizoma Cyperis, 5～7 parts, Radix Glycyrrhizae.
4. the preparation method of the Chinese medicine composition of the treatment prolapse of lumbar intervertebral disc as described in claim 1-3 any one, is characterized in that comprising the following steps:
A, dry crude drug is crushed to 100～120 orders, and mix homogeneously, in general ball pot, sprays water smoke, a small amount of medicated powder of spreading makes it to mix with water smoke, rotates general ball pot, and the brush medicated powder that wall adheres to of cooking makes medicated powder granule;
B, again to spraying mulse in the medicated powder granule in general ball pot and pot, the powder that spreads pesticides, rotate general ball pot, so iterative cycles is until by the general medicated powder spheroidal particle of making 0.8～1 millimeter of particle diameter of diameter, obtain ball mould;
C, the ball mould obtaining is rotated in general ball pot, on ball mould, with mulse moistening ball mould, the powder that spreads pesticides, repeatedly carry out, until molding reaches finished product water-honeyed pill prescribed level standard, final drying, collection, subpackage.
5. the preparation method of the Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc as claimed in claim 4, is characterized in that the every 100g medicated powder of described finished product water-honeyed pill refined honey used is 20～40g.
6. the preparation method of the Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc as claimed in claim 4, is characterized in that Mel in described mulse and the part by weight of water are: 1:3～1:4.
7. the preparation method of the Chinese medicine composition for the treatment of prolapse of lumbar intervertebral disc as claimed in claim 4, the diameter that it is characterized in that described finished product water-honeyed pill is 3～4 millimeters.
8. the preparation method of the Chinese medicine composition of the treatment prolapse of lumbar intervertebral disc as described in claim 1-3 any one, is characterized in that the raw material of described effective ingredient to be prepared into water decoction, tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
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| CN201310040204.3A Expired - Fee Related CN103041230B (en) | 2013-02-01 | 2013-02-01 | Traditional Chinese medicine composition for treating protrusion of lumbar intervertebral disc and preparation method of composition |
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Non-Patent Citations (2)
| Title |
|---|
| 中医药治疗腰椎间盘突出症的临床应用进展;李开静等;《中国现代医生》;20090131;第47卷(第2期);第41－42页 * |
| 李开静等.中医药治疗腰椎间盘突出症的临床应用进展.《中国现代医生》.2009,第47卷(第2期), |
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