CN103013137B - The preparation of albumen silkworm silk and the application in cosmetics - Google Patents
The preparation of albumen silkworm silk and the application in cosmetics Download PDFInfo
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- CN103013137B CN103013137B CN201110280370.1A CN201110280370A CN103013137B CN 103013137 B CN103013137 B CN 103013137B CN 201110280370 A CN201110280370 A CN 201110280370A CN 103013137 B CN103013137 B CN 103013137B
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Abstract
The preparation method that the present invention relates to a kind of albumen silkworm silk, and as the cosmetics additive application at cosmetic field. The present invention wraps up natural silk hydrolyzed protein silk peptide with natural macromolecular material for carrier and filmogen and makes silkworm silk shape product, adds in various transparent system cosmetics, increases aesthetic feeling. The above-mentioned natural macromolecular material as carrier and filmogen is sodium alginate, gellan gum, carrageenan and locust bean gum. Above-mentioned transparent system cosmetics, a class be with card ripple be suspending agent elite and gel rubber system, such as essence, elite stock solution, massage cream, fruit jelly facial film etc., another big class is SF-1 is suspending agent surfactant system, such as transparent cleansing milk, transparent bath foam, transparent shampoo etc.
Description
Art
The preparation method that the present invention relates to a kind of albumen silkworm silk, and as the cosmetics additive application at cosmetic field.
Background technology
Silk peptide is the active ingredient of native fibroin hydrolyzed solution, containing 18 seed amino acids, within 10 seconds, just can permeate skin skin corium, effectively suppresses melanin to generate, controls pigment. Promote collagen protein synthesis, activating cell, improve the immunity of cell, promote the metabolism rate of skin, help to repair impaired skin histology, make low and deep tired skin add life again, thus reducing the skin of whitening, gloss in very short time. Skin is had multiple efficacies by silk peptide as can be seen here. But silk peptide does not possess the threadlike appearance of silkworm silk, add to cosmetics can not give and experience intuitively.
At present, in cosmetic field, made granule, as the additive of cosmetics, is widely used, and adds a lot of colors and effect to cosmetics, also gives the more new meaning of cosmetics. Grain products includes soluble granule and insoluble granule (frosted granule), for the profile of granule, except rule spheroidal is exactly erose. But without silkworm silk shape.
The present invention, utilizes the film property of natural macromolecular material, by orifice coagulating bath method, parcel native fibroin hydrolyzed solution (silk peptide), makes silkworm silk shape product, adds in the cosmetics of transparent system. Namely this albumen silkworm silk have effect of natural silk hydrolyzed protein, has again the outward appearance of natural silk concurrently. Not only attractive in appearance but also practical.
Silk peptide, is that silkworm fibroin matter forms water miscible peptide material through degraded. Molecular weight is typically between 500��10000, good water solubility, white powder, pH value 4.5��6.5.
Silk peptide effect one, silk peptide has natural moisture preserving, nutrition skin and promotes skin wound healing effect: often smears skin with the skin care item rich in silk peptide and can reach beauty treatment and prevent the effect of various skin disease. Clinical application proves that: wrinkled skin, dermatitis, pruritus, elimination chloasma are had good curative effect. Test result indicate that, silk peptide nonirritant, and wound healing can be accelerated. Silk peptide still prevents dust, coating, acid, alkali chemical substance to the erosion of skin and injury.
Silk peptide effect two, extremely excellent hair care function: the hair care function of silk peptide is mainly reflected in the absorbability to hair and adsorptivity, film property, damping moisture retention.Absorbability and adsorptivity: silk peptide is compared with other hydrolyzed protein (collagen protein, osseocolla albumen, glutin etc.), and maximum feature is exactly nutritious easily absorbed by hair. Silk peptide relies primarily on osmosis for the absorption of skin and hair, has substantivity. Silk peptide concentration improves, then the absorbtivity of silk peptide is also increased by hair accordingly. If the hair of damaged, absorption and adsorbance to low-molecular-weight silk peptide are bigger, and correspondingly silk peptide is more obvious to reparation and the protective effect of hair. Molecular weight is at the silk peptide of 500-2000, and its film property on hair is fabulous, and the film distinctive gloss of tool, and hair good hand touch is flexible. X-ray diffraction method shows: the film that silk peptide is formed is �� type crystallization, the film that silk peptide is formed on hair, can increase hair elasticity and gloss. It also is used as hairspray simultaneously, PVP, collagen peptide, starch based aqueous solution and silk peptide is compared, under the wet condition of 80% relative humidity, makes setting agent with silk peptide, hair can be made to keep good hair style for a long time.
Silk peptide effect three, damping moisture retention: hair loses certain moisture and will dry, jag, easily snap off, come off. Silk peptide can prevent moisture content from too much evaporating at the film that hair surface is formed, as natural moisturizing factor, moreover it is possible to regulates the wettability in the little space of hair surface, makes hair soft, smooth.
Natural macromolecular material has and a variety of has gelation and film property, it is possible to for carrier and the filmogen of silk peptide, for instance: sodium alginate, gellan gum, carrageenan, locust bean gum.
Sodium alginate is a kind of natural polymer forming agent, Sargassum (Thallus Laminariae (Thallus Eckloniae), Brown algae, the edible marine algae plant such as Alga Sgrgassi Enerves Macrocystis pyrifera (L.) Ag.) extract the by-product of processing. Sodium alginate can make various gel, and keeps good colloid form, and sepage or contraction, satisfactory mechanical property do not occur, and is the fabulous novel carriers of a kind of stability and forming agent. Spherical additive (roe elite granule, the Jojoba granule) majority of present cosmetic field produces with sodium alginate for carrier and forming agent.
Gellan gum also known as triumphant can glue, be a kind of microorganism edible glue of exploitation Kelco company of U.S. eighties in 20th century. It is a kind of Linear Polymer polysaccharide, can form the gel of all-transparent, and its gelling performance is more more superior than xanthan gum. The solidification temperature of gellan gum gel is within the scope of 30-45 DEG C, and the fusion temperature of gel both can lower than being higher than 100 DEG C, and this depends on the condition such as cation type and concentration. Cationic existence simultaneously, can generate hard brittle gel, and its hardness is directly proportional to gellan gum concentration, and produces maximum gel hardness when relatively low divalent cation concentration. Add xanthan gum, locust bean gum in gellan gum, its gel hardness can be made to reduce and elastic enhancing, thus obtaining a kind of desirably filmogen and carrier.
Carrageenan is also known as carrageenin, Ireland extractum and antler glue, this is by D-galactopyranose and 3, the calcium of high molecular weight polysaccharide class sulfuric ester of 6-Anhydrogalactose. composition, magnesium, potassium, sodium, ammonium salt, according to sulfuric ester in molecule in conjunction with kenel, carrageenan is divided into 3 kinds of types: k-type, ��-type, L-type etc. Kappa-Carraginan is referred to as the quick carrageenan of potassium; L-carrageenan is then referred to as calciphylaxis carrageenan, L-carrageenan and calcium ion can be formed completely not syneresis, gel that is whippy and that glue very much, it is unique freeze thaw stable type carrageenan.When K-carrageenan is mixed with L-carrageenan, the elasticity that can improve gel can prevent again syneresis. Locust bean gum is mixed with carrageenan makes gel become more high resilience and not crisp, and the cooperative effect let us of both glue obtains again a kind of extraordinary silk peptide forming agent and carrier.
Locust bean gum, a kind of white to yellow powder, granule or flat sheet, odorless or be with micro-smelly, colourless, mainly contain mannose and gala warded off, molecular weight is approximately 300,000 dalton, is extremely good thickening stabilizing agent. Its most important feature is it and the hydrophilic colloid such as agar, carrageenan and xanthan gum has good gel cooperative effect, the consumption level after compound can be made very low and improve gel tissue's structure.
So far, make thread products application with natural macromolecular material have not been reported for carrier and film former parcel silk peptide at cosmetic field.
Summary of the invention
It is an object of the invention to provide a kind of method making silkworm silk shape product albumen silkworm silk with natural polymer filmogen parcel silk peptide, this albumen silkworm silk adds the intact guarantee threadlike appearance of energy in cosmetics to, reach the effect namely with natural silk hydrolyzed protein, have again the purpose of the outward appearance of natural silk concurrently.
Technical scheme one provided by the invention is:
Silk peptide is wrapped up for film former and carrier with sodium alginate, make albumen silkworm silk, its concrete grammar is: take the sodium alginate soln I of sodium alginate configuration 0.5��4% soluble in water, again silk peptide powder is joined in solution I, it is sufficiently mixed, making silk peptide concentration is 4��8%, obtain solution II, then orifice device is used, by solution II uninterruptedly to become the thread of drop to flow rapidly in 0.5��4% calcium chloride solution, obtain translucent thread product, after 30 minutes, taking-up washes with water to below 10PPm, obtains albumen silk product.
It should be understood that
The volume ratio of the amount of above-mentioned calcium chloride solution and sodium alginate soln II is 2: 1��5: 1, it is recommended to use volume ratio is 3: 1.
Technical scheme two provided by the invention is:
Silk peptide is wrapped up for film former and carrier so that gellan gum and locust bean gum are composite, make albumen silkworm silk, its concrete grammar is: take gellan gum, locust bean gum and silk peptide powder are added to the water, it is configured to the locust bean gum of the gellan gum containing 0.1��1% and 0.05��0.5%, the silk peptide of 4��8%, under stirring state, solution is heated to 60��70 degree and is incubated 20 minutes, allow three kinds of raw materials fully dissolve, obtain solution I; Take calcium chloride and be dissolved in the ethanol of 95% content, make the solution of 0.5��4%, be chilled in advance about 5 degree standby, obtain solution II, then use orifice device, by solution I uninterruptedly to become the thread of drop to flow rapidly in solution II, obtain translucent thread product, after 30 minutes, take out and wash with water to below 10PPm, obtain albumen silk product.
It should be understood that
The volume ratio of the amount of above-mentioned calcium chloride alcoholic solution II and carrier and film former solution I is 2: 1��5: 1, it is recommended to use volume ratio is 3: 1.
Technical scheme three provided by the invention is:
Using K-carrageenan and the composite film former as silk peptide of L-carrageenan and carrier, and add locust bean gum and improve its gelling performance, make albumen silkworm silk. Its concrete grammar is: takes K-carrageenan, L-carrageenan, locust bean gum and silk peptide powder and is added to the water, it is configured to the K-carrageenan containing isocyatic 0.05��1.0% and L-carrageenan, the locust bean gum of 0.02��0.05%, the silk peptide of 4��8%, by solution heating to boiling under stirring state, obtain solution I;Take calcium chloride and be dissolved in the ethanol of 95% content, make the calcium chloride solution of 0.5��4%, be chilled in advance about 5 degree standby, obtain solution II, then use orifice device, by solution I uninterruptedly to become the thread of drop to flow rapidly in solution II, obtain translucent thread product, after 30 minutes, take out and wash with water to below 10PPm, obtain albumen silk product.
It should be understood that
The volume ratio of the amount of above-mentioned calcium chloride alcoholic solution II and carrier and film former solution I is 2: 1��5: 1, it is recommended to use volume ratio is 3: 1.
Beneficial effect
With the albumen silkworm silk that above-mentioned three kinds of schemes obtain, there is good mechanical stability, can effectively wrap up silk peptide, it is ensured that its activity, temperature and acid-base value are had good toleration, there is the longer maintenance time limit, it is simple to store and transport. This albumen silkworm silk adds in transparence cosmetic system, remains to effectively keep threadlike appearance and ensure the stability of institute's contents of parcel thing silk peptide. Albumen silkworm silk is good with other components compatibilities of cosmetics, and only when making to apply some make up, albumen silkworm silk can be smeared easily and leach, the silk peptide of abrupt release parcel, is absorbed by the skin.
The diameter of this albumen silkworm silk can control at 0.2��2MM according to the size of orifice. The color of albumen silkworm silk can present multicoloured appearance colour according to the pigment difference added, such as add redness, yellow, blueness, green color lake, redness, yellow, blueness, green albumen silkworm silk can be respectively prepared, other colors can based on bluish-green four colors of reddish yellow mixing color out, the extreme enrichment color of albumen silkworm silk. It addition, add pearlescent pigment to give pearl effect to albumen silkworm silk, make albumen silkworm silk more attractive.
Albumen silkworm silk can add in multiple cosmetics, one class be with card ripple be suspending agent elite and gel rubber system, such as essence, elite stock solution, massage cream, fruit jelly facial film etc., another big class is SF-1 is suspending agent surfactant system, such as transparent cleansing milk, transparent bath foam, transparent shampoo etc.
Accompanying drawing explanation
Fig. 1: the albumen silkworm silk raw material of the present invention;
Fig. 2: the albumen silkworm silk of the present invention is suspended in essence;
Detailed description of the invention:
Embodiment 1:
Preparing albumen silkworm silk with sodium alginate for carrier and film former, specific practice is:
It is dissolved in 93ml water with 2 grams of sodium alginates and is configured to sodium alginate soln I. Again 0.1 gram of ultra-fine moisture is dissipated titanium dioxide and 5 grams of silk peptide powder join in solution I, be sufficiently stirred for and dissolve so that silk peptide ultimate density is 5%, and sodium alginate concentration is 2%, obtains solution II. Then use syringe that solution II is rapidly injected 300mL, in the calcium chloride solution of 4%, inject complete standing 30 minutes, take out and wash with water to below 10PPm, obtain white protein silkworm silk.
Embodiment 2:
Albumen silkworm silk is suspended in transparent moisturizing essence, and specific practice is:
Beaker is sequentially added into 0.2 gram of hyaluronate sodium, glycerol 5 grams, propylene glycol 5 grams, amino acid humectant 5 grams, the carbomer solution 20 grams of the model 941 that 1% use water is pre-dispersed, 50 grams of water, appropriate triethanolamine, Preservative Technology for Personal Care and essence, be uniformly mixed and get final product, add albumen silkworm silk 2 grams, finally add water to 100 grams.
Embodiment 3:
Albumen silkworm silk is suspended in moisturizing massage curry, and specific practice is:
Beaker is sequentially added into 0.2 gram of hyaluronate sodium, glycerol 5 grams, propylene glycol 5 grams, reed bar gel 5 grams, the SF-1 suspending agent of 30% 8 grams, 50 grams of water, appropriate triethanolamine, Preservative Technology for Personal Care and essence, it is eventually adding albumen silkworm silk 2 grams, is uniformly mixed, finally add water to 100 grams.
Embodiment 4:
Albumen silkworm silk is suspended in the transparent cleansing milk of low stimulation, and specific practice is:
Beaker adds 50 grams of water, 1.5 grams of Acritamer 940s, dispersed with stirring, available homogenizer homogenous disperse, it is sequentially added into 5 gram calorie ripple companions 1225 and 18 grams of CAB-35, sequentially add 0.65 gram of Sal, appropriate essence, preservative and TEA, stir, add 3 grams of dispersed with stirring of albumen silkworm silk uniform, finally add water to 100 grams.
Claims (9)
1. the preparation method of an albumen silkworm silk, it is characterized in that: wrap up silk peptide with sodium alginate for carrier and film former, the concrete grammar of scheme one is: take the sodium alginate soln I of sodium alginate configuration soluble in water 0.5-4%, again silk peptide powder is joined in solution I, it is sufficiently mixed, making silk peptide concentration is 4-8%, obtain solution II, then orifice device is used, by solution II uninterruptedly to become the thread of drop to flow rapidly in 0.5-4% calcium chloride solution, obtain translucent thread product, after 30 minutes, taking-up washes with water to below 10PPm, obtain albumen silk product, the volume ratio of the amount of above-mentioned calcium chloride solution and sodium alginate soln II recommends 3:1.
2. the preparation method of albumen silkworm silk according to claim 1, it is characterized in that: wrap up silk peptide with sodium alginate for carrier and film former, it is dissolved in 93ml water with 2 grams of sodium alginates and is configured to sodium alginate soln I, again 0.1 gram of ultra-fine moisture is dissipated titanium dioxide and 5 grams of silk peptide powder join in solution I, it is sufficiently stirred for and dissolves, making silk peptide ultimate density is 5%, sodium alginate concentration is 2%, obtain solution II, then use syringe that solution II is flowed rapidly into 300ml, in the calcium chloride solution of 4%, inject complete standing 30 minutes, taking-up washes with water to below 10PPm, obtain white protein silkworm silk.
3. the preparation method of an albumen silkworm silk, it is characterized in that: wrap up silk peptide so that gellan gum and locust bean gum are composite for film former and carrier, make albumen silkworm silk, the concrete grammar of scheme two is: takes gellan gum, locust bean gum and silk peptide powder and is added to the water, is configured to the secondary locust bean gum of the gellan gum containing 0.1-1% and 0.05-0.5%, the silk peptide of 4-8%, under stirring state, solution is joined 60-70 degree and is incubated 20 minutes, allow three kinds of raw materials fully dissolve, obtain solution I; Take calcium chloride and be dissolved in the ethanol of 95% content, make the solution of 0.5-4%, be chilled in advance 5 degree standby, obtain solution II, then use orifice device, by solution I uninterruptedly to become the thread of drop to flow rapidly in solution II, obtain translucent thread product, after 30 minutes, take out and wash with water to below 10PPm, obtaining albumen silk product, the amount of above-mentioned calcium chloride alcoholic solution II and the volume ratio of solution I recommend 3:1.
4. the preparation method of an albumen silkworm silk, it is characterized in that: using K-carrageenan and the composite film former as silk peptide of L-carrageenan and carrier, and add locust bean gum and improve its gelling performance, make artificial silkworm silk, the concrete grammar of scheme three is: takes K-carrageenan, L-carrageenan, locust bean gum and silk peptide powder and is added to the water, it is configured to the K-carrageenan containing isocyatic 0.05-1.0% and L-carrageenan, the locust bean gum of 0.02-0.05%, the silk peptide of 4-8%, by solution heating to boiling under stirring state, obtain solution I; Take calcium chloride and be dissolved in the ethanol of 95% content, make the calcium chloride solution of 0.5-4%, be chilled in advance 5 degree standby, obtain solution II, then use orifice device, by solution I uninterruptedly to become the thread of drop to flow rapidly in solution II, obtain translucent thread product, after 30 minutes, take out and wash with water to below 10PPm, the volume ratio obtaining albumen silk product, the amount of above-mentioned calcium chloride alcoholic solution II and carrier and film former solution I recommends as 3:1.
5. according to claim 1, the preparation method of the albumen silkworm silk described in 3 or 4, it is characterized in that: the diameter of albumen silkworm silk can control at 0.2-2mm according to the size of orifice, the color of albumen silkworm silk can present multicoloured appearance colour according to the pigment difference added, add redness, yellow, blue, green color forms sediment, redness can be respectively prepared, yellow, blue, green albumen silkworm silk, other colors can mixing color be out based on bluish-green four colors of reddish yellow, the extreme enrichment color of albumen silkworm silk, additionally, add pearlescent pigment and give pearl effect to albumen silkworm silk.
6. the preparation method of the albumen silkworm silk according to claim 1,3 or 4, it is characterized in that: albumen silkworm silk can add in multiple cosmetics, a class be with card ripple be suspending agent elite and gel rubber system: essence, elite stock solution, massage cream, fruit jelly facial film; Another big class is SF-1 is suspending agent surfactant system: transparent cleansing milk, transparent bath foam, transparent shampoo.
7. the preparation method of the albumen silkworm silk according to claim 1,3 or 4, it is characterised in that: albumen silkworm silk is suspended in transparent moisturizing essence, is sequentially added into 0.2 gram of hyaluronate sodium in beaker, glycerol 5 grams, propylene glycol 5 grams, amino acid humectant 5 grams, the carbomer solution 20 grams of the model 941 that 1% use water is pre-dispersed, 50 grams of water, appropriate triethanolamine, Preservative Technology for Personal Care and essence, be uniformly mixed and get final product, add albumen silkworm silk 2 grams, finally add water to 100 grams.
8. the preparation method of the albumen silkworm silk according to claim 1,3 or 4, it is characterised in that: albumen silkworm silk is suspended in moisturizing massage curry, is sequentially added into 0.2 gram of hyaluronate sodium in beaker, glycerol 5 grams, propylene glycol 5 grams, reed bar gel 5 grams, the SF-1 suspending agent of 30% 8 grams, 50 grams of water, appropriate triethanolamine, Preservative Technology for Personal Care and essence, be eventually adding albumen silkworm silk 2 grams, it is uniformly mixed, finally adds water to 100 grams.
9. the preparation method of the albumen silkworm silk according to claim 1,3 or 4, it is characterised in that: albumen silkworm silk is suspended in the transparent cleansing milk of low stimulation, adds 50 grams of water in beaker, 1.5 grams of Acritamer 940s, dispersed with stirring, available homogenizer homogenous disperse, it is sequentially added into 5 gram calorie ripple companions 1225 and 18 grams of CAB-35, sequentially add 0.65 gram of Sal, appropriate essence, preservative and TEA, stir, add 3 grams of dispersed with stirring of albumen silkworm silk uniform, finally add water to 100 grams.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105267059A (en) * | 2014-07-24 | 2016-01-27 | 云山国际生技股份有限公司 | Colloid, color-changing film set and preparation method thereof |
| CN104188862B (en) * | 2014-08-28 | 2017-12-26 | 中国水稻研究所 | A kind of skin care scrub cream and preparation method thereof |
| KR20160110769A (en) * | 2015-03-12 | 2016-09-22 | 코스맥스 주식회사 | Composition for gel mask pack |
| CN105461940B (en) * | 2015-12-22 | 2018-03-16 | 福州大学 | A kind of natural polymer absorbent material and preparation method thereof |
| CN106491494A (en) * | 2016-11-25 | 2017-03-15 | 江苏爱西施科技服务咨询股份有限公司 | A kind of silk Moisturizer and preparation method thereof |
| CN107083674B (en) * | 2017-05-25 | 2019-10-15 | 南京林业大学 | A kind of preparation method of silk nanofiber dispersion liquid |
| CN110496069A (en) * | 2019-06-05 | 2019-11-26 | 王晓霞 | A kind of poly- peptide stoste of small molecule and preparation method thereof |
| CN111110586B (en) * | 2020-01-09 | 2022-06-10 | 厦门市斯维特日用品有限公司 | Preparation method of protein composition in washing and caring product |
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| CN1562389A (en) * | 2004-03-19 | 2005-01-12 | 清华大学 | Mineralized fibrion/macromolecule composite porous material and preparation method |
| CN1985791A (en) * | 2006-12-27 | 2007-06-27 | 浙江大学 | Preparing process of skin care silk protein gel cream |
| CN102008753A (en) * | 2010-12-23 | 2011-04-13 | 福州大学 | Organic-inorganic composite gel material for bone repair and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1562389A (en) * | 2004-03-19 | 2005-01-12 | 清华大学 | Mineralized fibrion/macromolecule composite porous material and preparation method |
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