CN103007297A - Preparation method of lubricating agent for gastroscope - Google Patents
Preparation method of lubricating agent for gastroscope Download PDFInfo
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- CN103007297A CN103007297A CN2012105693572A CN201210569357A CN103007297A CN 103007297 A CN103007297 A CN 103007297A CN 2012105693572 A CN2012105693572 A CN 2012105693572A CN 201210569357 A CN201210569357 A CN 201210569357A CN 103007297 A CN103007297 A CN 103007297A
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- lidocaine hydrochloride
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- gastroscope
- starch
- preparation
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Abstract
The invention provides a preparation method of a lubricating agent for gastroscope. The lubricating agent is prepared by the following raw materials of, by weight, 80-120 parts of lidocaine hydrochloride, 7,800-8,200 parts of glycerin, 550-650 parts of starch and 1,250-1,325 parts of distilled water. The preparation method comprises the steps of adding the lidocaine hydrochloride in a stainless steel container with the distilled water; heating to a temperature of 65-75 DEG C; stirring thoroughly to make the lidocaine hydrochloride dissolved, so that a lidocaine hydrochloride solution is obtained; adding the starch and the glycerin in another stainless steel container; mixing uniformly with stirring; adding the lidocaine hydrochloride solution in the mixture; stirring continuously until the solution is boiled and becomes a paste; sub-packaging the paste; and sterilizing for 30 minutes at a temperature of 100 DEG C, so that a finished product of the lubricating agent is obtained. When the lubricating agent is in use, the lubricating agent is uniformly sprayed on the surface of a gastroscope probe, with 8-10 grams one time.
Description
Technical field
The present invention relates to medical lubricant, cooperate the inspection of its gastroscope, can effectively alleviate the misery that is subjected to the user, have important use value.
Background technology
The lubricant that existing market is sold is mainly by dimethicone, potassium sorbate, defoamer, deionized water, or glycerol, xanthan gum, Rikemal B 200, distilled water, or the compositions such as glycerol, xanthan gum, dimethicone, Metagin, second fat, edible essence and distilled water; Literature search also discloses simultaneously: 1. the development and production of the Kang Yuan of Henan Province biotechnology company limited " Shan Laite " board gastroscope lubricant, its effective ingredient is: dimethicone, potassium sorbate, defoamer, deionized water.2. Jinfang Biological Medicine Incubator Co., Ltd., Dongguan's development and production " smooth peaceful " board body cavity import lubricating fluid, its effective ingredient is: glycerol, xanthan gum, Rikemal B 200, distilled water etc. are applicable to gastroscope inspection, cystoscopy, microscopic examination of rectum, import lubricated using when prostate refers to examine.3. Shenzhen's " free from worries " board body cavity apparatus guiding lubricant of having contained the development and production of safe medical apparatus and instruments company limited, its effective ingredient is comprised of glycerol, xanthan gum, dimethicone, Metagin, second fat, edible essence and distilled water etc., do to import lubricated etc. during for catheter, cystourethroscope, gastroscope intubate.
Lubricant formulations of the present invention mainly is comprised of lidocaine hydrochloride, distilled water, glycerol, starch, has drug safety, the speciality that result of use is splendid.
Summary of the invention
The object of the invention is to: provide lubricant to spread upon the lubricity that gastroscope apparatus surface increases the gastroscope apparatus, make it arrive rapidly lesions position and carry out disease detection, play the double effects of lubricated and local anaesthesia.
The object of the present invention is achieved like this: a kind of preparation method of gastroscope lubricant, and raw material is prepared with parts by weight: be comprised of lidocaine hydrochloride 80-120 part, 8200 parts of glycerol 7800-, starch 550-650 part, distilled water 1250-1325 part; Preparation: get the lidocaine hydrochloride adding and be equipped with in the rustless steel container of distilled water, be warming up to 65-75 ℃, fully stirring and dissolving gets lidocaine hydrochloride solution; Other adds starch and glycerol in another stainless container, mixes, and with the adding of lidocaine hydrochloride solution, ceaselessly stirs again, until boiling generates pasty state, namely sterilizes 30 minutes under 100 ℃ after the packing, namely gets the lubricant finished product; During use, lubricant is evenly spread upon the gastroscope probe surface, each consumption is the 8-10 gram.
Design of the present invention and technique effect: by the gastroscope lubricant of local anaesthetics, the preparation of lubricant prescription, spread upon the gastroscope apparatus surface of having sterilized, not only increased the lubricity of gastroscope apparatus, patient's sense of discomfort is alleviated, make it in the easier insertion Stomach in Patients, arrive rapidly lesions position, carry out the detection of disease; Product of the present invention is accepted by the user, has reduced the use metering of anesthetics, reduces medical cost, shows technological progress.
The specific embodiment
The present invention is described further in conjunction with the embodiments.
Embodiment
Raw material is prepared with parts by weight:
1) gets 80 parts of lidocaine hydrochlorides, 7800 parts of glycerol, 550 parts of starch, 1250 parts of compositions of distilled water;
2) get 120 parts of lidocaine hydrochlorides, 8200 parts of glycerol, 650 parts of starch, 1325 parts of compositions of distilled water;
3) 100 parts of lidocaine hydrochlorides, 8000 parts of glycerol, 600 parts of starch, 1300 parts of compositions of distilled water;
With 1) or 2) or 3) selecting one group, preparation: lidocaine hydrochloride is placed the rustless steel container that distilled water is housed, be warming up to 65 or 75 ℃, fully stirring and dissolving gets lidocaine hydrochloride solution; In addition starch and glycerol are added in another stainless container, mix, again lidocaine hydrochloride solution is added in the mixture of starch and glycerol, ceaselessly stir, until boiling generates pasty state, i.e. packing, under 100 ℃, sterilized 30 minutes, namely get the lubricant finished product; Use usage: lubricant is evenly spread upon the gastroscope probe surface, and each consumption is 8 or 9 or 10 grams.
The lidocaine hydrochloride that this method is selected is produced by Shanxi Xin Baoyuan pharmaceutical Co. Ltd; Starch is produced by North China pharmacy Kang Xin company limited; Glycerol is produced by Nanchang white clouds pharmaceutcal corporation, Ltd.
The compound national Application standard of the lidocaine hydrochloride that this product is selected.
Claims (2)
1. the preparation method of a gastroscope lubricant, it is characterized in that: raw material is prepared with parts by weight: be comprised of lidocaine hydrochloride 80-120 part, 8200 parts of glycerol 7800-, starch 550-650 part, distilled water 1250-1325 part; Preparation: get the lidocaine hydrochloride adding and be equipped with in the rustless steel container of distilled water, be warming up to 65-75 ℃, fully stirring and dissolving gets lidocaine hydrochloride solution; Other adds starch and glycerol in another stainless container, mixes, and with the adding of lidocaine hydrochloride solution, ceaselessly stirs again, until boiling generates pasty state, namely sterilizes 30 minutes under 100 ℃ after the packing, namely gets the lubricant finished product; During use, lubricant is evenly spread upon the gastroscope probe surface, each consumption is the 8-10 gram.
2. according to right 1 described method, it is characterized in that: the lidocaine hydrochloride of selecting is produced by Shanxi Xin Baoyuan pharmaceutical Co. Ltd; Starch is produced by North China pharmacy Kang Xin company limited; Glycerol is produced by Nanchang white clouds pharmaceutcal corporation, Ltd.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105693572A CN103007297A (en) | 2012-12-25 | 2012-12-25 | Preparation method of lubricating agent for gastroscope |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105693572A CN103007297A (en) | 2012-12-25 | 2012-12-25 | Preparation method of lubricating agent for gastroscope |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103007297A true CN103007297A (en) | 2013-04-03 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012105693572A Pending CN103007297A (en) | 2012-12-25 | 2012-12-25 | Preparation method of lubricating agent for gastroscope |
Country Status (1)
| Country | Link |
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| CN (1) | CN103007297A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110947008A (en) * | 2019-12-20 | 2020-04-03 | 郑州弘新医疗科技有限公司 | Orally-taken oxybuprocaine hydrochloride gastroscope lubricating liquid and preparation method thereof |
| CN114569804A (en) * | 2022-03-03 | 2022-06-03 | 上海中医药大学附属岳阳中西医结合医院 | Enteroscope lubricant and preparation method and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101322848A (en) * | 2008-07-28 | 2008-12-17 | 上海艾韦特医药科技有限公司 | Composition for gastroscopy and preparation thereof |
| CN101385702A (en) * | 2008-09-26 | 2009-03-18 | 浙江康德药业集团有限公司 | Lidocaine hydrochloride mucilage preparation method |
-
2012
- 2012-12-25 CN CN2012105693572A patent/CN103007297A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101322848A (en) * | 2008-07-28 | 2008-12-17 | 上海艾韦特医药科技有限公司 | Composition for gastroscopy and preparation thereof |
| CN101385702A (en) * | 2008-09-26 | 2009-03-18 | 浙江康德药业集团有限公司 | Lidocaine hydrochloride mucilage preparation method |
Non-Patent Citations (2)
| Title |
|---|
| 朱功新 等: "盐酸丁卡因胶冻的处方与配制", 《海峡药学》, vol. 17, no. 2, 30 April 2005 (2005-04-30) * |
| 邓昌国 等: "胃镜润滑剂的质量控制", 《解放军药学学报》, vol. 26, no. 6, 20 December 2010 (2010-12-20) * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110947008A (en) * | 2019-12-20 | 2020-04-03 | 郑州弘新医疗科技有限公司 | Orally-taken oxybuprocaine hydrochloride gastroscope lubricating liquid and preparation method thereof |
| CN110947008B (en) * | 2019-12-20 | 2022-03-18 | 郑州弘新医疗科技有限公司 | Orally-taken oxybuprocaine hydrochloride gastroscope lubricating liquid and preparation method thereof |
| CN114569804A (en) * | 2022-03-03 | 2022-06-03 | 上海中医药大学附属岳阳中西医结合医院 | Enteroscope lubricant and preparation method and application thereof |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130403 |