CN103007042A - Traditional Chinese medicine composition for treating gastric ulcer - Google Patents
Traditional Chinese medicine composition for treating gastric ulcer Download PDFInfo
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- CN103007042A CN103007042A CN2012105451677A CN201210545167A CN103007042A CN 103007042 A CN103007042 A CN 103007042A CN 2012105451677 A CN2012105451677 A CN 2012105451677A CN 201210545167 A CN201210545167 A CN 201210545167A CN 103007042 A CN103007042 A CN 103007042A
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Abstract
The invention provides a traditional Chinese medicine composition for treating gastric ulcer, wherein amblygonon orientale nakai and cuttlebone are used as a monarch drug for replenishing qi to invigorate spleen, clearing away heat and promoting dieresis, and dispersing blood stasis and relieving pain; and costustoot, radix angelicae, rhizoma atractylodis macrocephalae and cortex moutan are used as a ministerial drug for enhancing effects. Meanwhile, the costustoot further enables qi of tri-jiao to be ventilated, so as to recover the function of middle burner spleen and stomach lowering; the spleen prefers moisture to dryness and the rhizoma atractylodis macrocephalae can eliminate dampness and realize diuresis, so as to further enhance spleen and stomach functions, and keep healthy and do not be evil; and the function of removing blood stasis and producing new blood of the radix angelicae and the cortex moutan are adopted. Rhizoma bletillae and roasted concha arcae are used as adjuvant drugs to enhance hyperacidity relieving and skin generating functions. When the spleen and the stomach are healthy, qi is promoted and the blood stasis is removed and wetting heat is removed; and all the medicines are combined so as to replenish qi to invigorate the spleen, clear away heat and promote diuresis, remove blood stasis and relieve pain, and relieve hyperacidity and generate skin. The clinical utilization shows that the traditional Chinese medicine composition has the reliable curative effect on treating the gastric ulcer and has no untoward effects; and the traditional Chinese medicine composition can be accepted by vast gastric ulcer patients and is worthy of being popularized. The total effective rate is 90.5% and the traditional Chinese medicine composition is an effective drug for treating the gastric ulcer.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate to a kind of Chinese medicine composition for the treatment of gastric ulcer.
Background technology
Gastric ulcer be since to gastric mucosa have detrimental effect the invasion and attack factor and mucosa self-defense/reparation factor between unbalanced result.Gastric mucosa is except the gastric acid of frequent contact high concentration, also be subject to the invasion and attack of pepsin, microorganism, cholate, ethanol, medicine and other harmful substances, under normal circumstances, gastric mucosa can be resisted the detrimental effect of these invasion and attack factors, keep the integrity of mucosa, but strengthen in the invasion and attack factor, or when defence/reparation factor weakens, or both are when existing simultaneously, can cause the generation of gastric ulcer.Clinical manifestation is: upper abdomen middle part, the rhythmicity pain that takes over or take back, and acid regurgitation, belch, heartburn, Abdeminal pain is felt sick, vomiting, loss of appetite etc.
Gastric ulcer belongs to the categories such as the traditional Chinese medical science " gastric abscess ", " acid regurgitation ", and sick position is at stomach, and is closely related with liver, spleen.Stomach is burnt between two parties, the main digesting food of being received, with reduce to suitable.Stomach links to each other with film with spleen, the exterior and the interior each other, and The spleen has the function to transport and transform nutrients, rises then strongly, and the two one rise and one drop is the important department of ascending or descending movement of vital Qi, and liver controlling conveyance and dispersion helps the fluent middle burnt mechanism of qi of taste.Improper diet and overtiredness, spleen and stomach function is impaired, transformation failure of spleen, functional activity of QI being not smooth; Liver-QI transversely invading the stomach, the liver failing to dredge the spleen, dysfunction of the spleen in transportation, stomach-QI being unable to descend normally, depression and stagnation of QI, the stomach network is obstructed, stagnation of QI and blood may bring about pain; The delicious food of being addicted to drink, retention of damp-heat in the interior, stomach loses and makes moist; The sick for a long time blood stasis of blood stagnates; Do not allow then pain.Simultaneously, hyperactive liver-QI attacking the stomach, Jiao also can cause acid regurgitation in the retention of damp-heat in the interior, and the disease of clinical findings is often complicated and changeable, simulataneous insufficiency and excessive.Chinese medicine is improving symptom, is improving and to have larger advantage,, few side effects low than the western medical treatment relapse rate aspect the ulcer healing quality.(Wang Yu, Xie Peilin, the progress of Chinese medicine gastric ulcer [J], the Hubei Journal of Traditional Chinese Medicine, 2012,34(10): 77-79.)
Summary of the invention
The traditional Chinese medical science is thought the generation of gastric ulcer, mainly is because eating and drinking without temperance, feelings will are smooth, overstrain internal injury etc. causes the spleen and stomach function weakness, transformation failure of spleen, and ascending or descending movement of vital Qi is not normal; Or depression and stagnation of QI, hematogenous blockage with the passing of time, stasis blocking stomach network; Or due to the retention of damp-heat in the interior etc.
Chinese medicine for abundant treatment gastric ulcer the invention provides a kind of Chinese medicine composition for the treatment of gastric ulcer.
The invention provides a kind of Chinese medicine composition for the treatment of gastric ulcer, composition and the mass ratio of its prescription are as follows: the mass ratio of bright pink son, Endoconcha Sepiae, the Radix Aucklandiae, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Pseudobulbus Bletillae (Rhizoma Bletillae) and Concha Arcae (calcined) is 2:3:1:2:3:2:2:2.
Bright pink son enters liver, stomach, spleen three warps.The repercussive eliminating stagnation is arranged, invigorating spleen to remove dampness, the effect of clearing away heat to alleviate pain.The effect of " not Lu " Yan Qiyou " QI invigorating "." Chinese herbal medicine is commonly used in Shanghai " says its " loose blood, removing food stagnancy, pain relieving ".Modern study, it can be used for the treatment of gastric ulcer.Endoconcha Sepiae, " book on Chinese herbal medicine is new again " Yan Qike enters spleen channel.Dehumidifying is arranged, the effect of astringing to arrest bleeding, antacid sore." modern Practical Chinese medicinal " claims it: " for antacid, effective to hyperchlorhydria, gastric ulcer ".Modern pharmacological research shows that it contains calcium carbonate, can do the antacid agent.The two is monarch drug.
The Radix Aucklandiae can enter spleen, stomach, Liver Channel, and the gas that stagnates of kind current taste is the key medicine of promoting the circulation of QI to relieve pain.Compendium of Material Medica speech: " Radix Aucklandiae is the medicine of three warmers edema caused by disorder of QI, all gas of energy lifting ".The Radix Angelicae Dahuricae is returned the stomach warp, has dampness, an evacuation of pus of invigorating blood circulation, the effect of granulation promoting pain relieving, and it is kind in Yangming Channel damp.The Compendium of Material Medica speech: " row hands sun is bright for the Radix Angelicae Dahuricae, the white acrid in the mouth of color; Gas warm in nature is thick, and row foot sun is bright; Be the bright principal agent of sun, thus disorders of blood can be controlled again, and the pain relieving of evacuation of pus granulation promoting ".Therefore, and the usefulness Radix Angelicae Dahuricae " broken stagnated blood is mended fresh blood ... the pain relieving granulation promoting " (" Japan hanako materia medica ").The Rhizoma Atractylodis Macrocephalae is returned spleen, stomach warp, invigorating the spleen and benefiting QI is arranged, the effect of dampness diuretic." Rhizoma Atractylodis Macrocephalae is to foster taste ... help digestion except the key medicine of painful abdominal mass also.Insufficiency of the spleen strong, art can be mended it, and insufficiency of stomach is not received, and art can help it " (" book on Chinese herbal medicine converges and says "), modern pharmacological research shows: the card Rhizoma Atractylodis Macrocephalae of ulcer, and can pus expelling by strengthening vital QI.Cortex Moutan, clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.It can " control the intestines and stomach hematocele, epistaxis, haematemesis ... " (" pearl sac "), " settling five organs is treated the carbuncle skin ulcer " (Shennong's Herbal).Modern pharmacological research shows that its contained paeonol and glucosides constituents in addition thereof all have antiinflammatory action; Paeonol has the effects such as analgesia, antiulcer simultaneously.Four is ministerial drug.
" Pseudobulbus Bletillae (Rhizoma Bletillae), astringing QI ooze expectorant, hemostasis, the medicine of eliminating carbuncle is also " (" book on Chinese herbal medicine converges and says "), enter liver, stomach warp with it, hemostasis, detumescence, granulation promoting, sore.Modern pharmacological research shows, 1% Pseudobulbus Bletillae (Rhizoma Bletillae) decoct gavage, and the rat pipe film injury that hydrochloric acid is caused has protective effect; Experimental Stomach duodenum perforation has therapeutical effect to anesthetized dog.Concha Arcae (calcined) can enter stomach, Liver Channel, has the effect of relieving gastric hyperacidity to alleviate stomachache." Peptic Ulcers is controlled in relieving gastric hyperacidity to alleviate stomachache " (" Shandong Chinese herbal medicine handbook.Modern pharmacological research shows that this product master contains calcium carbonate, in the energy and gastric acid, alleviates the pain of gastric ulcer.The two is adjuvant drug.
Bright pink son, Endoconcha Sepiae are monarch drug, replenishing QI to invigorate the spleen, clearing away heat-damp and promoting diuresis, blood-activating analgetic.The Radix Aucklandiae, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan are ministerial drug, and principal drug assistance is strengthened effect.Simultaneously, also can the pass through gas of three warmers of the Radix Aucklandiae, burnt spleen rises the merit that stomach falls in the recovery; " spleen preferring dryness to dampness ", but the Rhizoma Atractylodis Macrocephalae further strong spleen and stomach function of dampness diuretic also reach " healthy energy deposit in, heresy can not be done "; Other gets the merit of the Radix Angelicae Dahuricae, Cortex Moutan eliminating blood stasis to promote regeneration of blood.Take Pseudobulbus Bletillae (Rhizoma Bletillae) and Concha Arcae (calcined) the two as adjuvant drug, to strengthen the effect of antacid, granulation promoting.
The invention provides a kind of Chinese medicine composition for the treatment of gastric ulcer, prescription is scientific and reasonable.Both logical traditional Chinese medical science pharmacology had again the modern medicine technology to be evidence.The strong then gas clots absorbing of taste is dispelled, and heat of wetting removes, and all medicines share, replenishing QI to invigorate the spleen, clearing away heat-damp and promoting diuresis, stasis-dispelling and pain-killing, antacid granulation promoting.
A kind of Chinese medicine composition for the treatment of hyperlipemia provided by the invention adopts the agent of prior art granulation.
Instructions of taking is as follows: with the granules medicine of above-mentioned 1 dosage, pour in the container, add warm water 300mL, stir and make it abundant mixing, day 2 times, early sub-service in 1 hour after ante cibum, the supper, 1 dose of every day.1 dosage such as embodiment 1.Treatment time is totally 28 days 1 course for the treatment of.
Taboo: this Chinese medicine composition allergy sufferers is forbidden.
Criterion of therapeutical effect and therapeutic outcome:" new Chinese medicine guideline of clinical investigations (trying) ", Beijing, Chinese Medicine science and technology publishing house, 2002:151-155.), it is as follows to decide criterion of therapeutical effect:
Recovery from illness: inflammation all disappeared around ulcer reached.
Produce effects: ulcer disappears, and still has inflammation.
Effectively: ulcer area is dwindled more than 50%.
Invalid: ulcer area is dwindled not as good as 50%.
Treatment case and therapeutic effect statistics:According to mentioned above principle and criterion of therapeutical effect, use Drug therapy patients w ith peptic ulcer disease 126 examples of the present invention, wherein, male 70 examples, women 56 examples; 30～66 years old age.Take medicine 1 course for the treatment of 33 examples of fully recovering, produce effects 36 examples, totally 69 examples, male 36 examples, women 33 examples, cure-remarkable-effectiveness rate 54.8% by instructions of taking.Effective 45 examples, male 27 examples, women 18 examples, effective percentage is 35.7%.Invalid totally 12 examples, male 7 examples, women 5 examples; Be 9.5%.
Total effective rate is cure-remarkable-effectiveness rate+effective percentage, and total effective rate is 90.5%.Treatment time is totally 28 days 1 course for the treatment of.
Beneficial effect:A kind of Chinese medicine composition for the treatment of gastric ulcer provided by the invention, bright pink son, Endoconcha Sepiae are monarch drug, replenishing QI to invigorate the spleen, clearing away heat-damp and promoting diuresis, blood-activating analgetic.The Radix Aucklandiae, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan are ministerial drug, and principal drug assistance is strengthened effect.The Radix Aucklandiae gas of three warmers that also can pass through simultaneously, burnt spleen rises the merit that stomach falls in the recovery; " spleen preferring dryness to dampness ", but Rhizoma Atractylodis Macrocephalae dampness diuretic also, further strong spleen and stomach function reaches " healthy energy deposit in, heresy can not be done "; Other gets the merit of the Radix Angelicae Dahuricae, Cortex Moutan eliminating blood stasis to promote regeneration of blood.Take Pseudobulbus Bletillae (Rhizoma Bletillae) and Concha Arcae (calcined) the two as adjuvant drug, to strengthen the effect of antacid, granulation promoting.The strong then gas clots absorbing of taste is dispelled, and heat of wetting removes, and all medicines share, replenishing QI to invigorate the spleen, clearing away heat-damp and promoting diuresis, stasis-dispelling and pain-killing, antacid granulation promoting.Clinical showing, a kind of Chinese medicine composition for the treatment of gastric ulcer provided by the invention, treatment gastric ulcer curative effect is reliable, and has no adverse reaction, and can be accepted by vast patients w ith peptic ulcer disease, and clinic is promoted.Its total effective rate is 90.5%, is a kind of active drug that is used for the treatment of gastric ulcer.
The specific embodiment
Embodiment 1A kind of Chinese medicine composition for the treatment of gastric ulcer, composition and the mass ratio of its prescription are as follows: bright pink sub-10g, Endoconcha Sepiae 15g, Radix Aucklandiae 5g, Radix Angelicae Dahuricae 10g, Rhizoma Atractylodis Macrocephalae 15g, Cortex Moutan 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g and Concha Arcae (calcined) 10g.
A kind of Chinese medicine composition for the treatment of hyperlipemia provided by the invention adopts the agent of prior art granulation.
Instructions of taking is as follows: with the granules medicine of above-mentioned 1 dosage, pour in the container, add warm water 300mL, stir and make it abundant mixing, day 2 times, early sub-service in 1 hour after ante cibum, the supper, 1 dose of every day.Treatment time is totally 28 days 1 course for the treatment of.
Taboo: this Chinese medicine composition allergy sufferers is forbidden.
Criterion of therapeutical effect and therapeutic outcome:" new Chinese medicine guideline of clinical investigations (trying) ", Beijing, Chinese Medicine science and technology publishing house, 2002:151-155.), it is as follows to decide criterion of therapeutical effect:
Recovery from illness: inflammation all disappeared around ulcer reached.
Produce effects: ulcer disappears, and still has inflammation.
Effectively: ulcer area is dwindled more than 50%.
Invalid: ulcer area is dwindled not as good as 50%.
Claims (2)
1. a Chinese medicine composition for the treatment of gastric ulcer is characterized in that, composition and the mass ratio of its prescription are as follows: the mass ratio of bright pink son, Endoconcha Sepiae, the Radix Aucklandiae, the Radix Angelicae Dahuricae, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Pseudobulbus Bletillae (Rhizoma Bletillae) and Concha Arcae (calcined) is 2:3:1:2:3:2:2:2.
2. the Chinese medicine composition for the treatment of gastric ulcer as claimed in claim 1 is characterized in that, composition and the quality of its prescription are as follows: bright pink sub-10g, Endoconcha Sepiae 15g, Radix Aucklandiae 5g, Radix Angelicae Dahuricae 10g, Rhizoma Atractylodis Macrocephalae 15g, Cortex Moutan 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g and Concha Arcae (calcined) 10g.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1343508A (en) * | 2001-01-09 | 2002-04-10 | 刘宝泉 | Chinese patent medicine for treating peptic ulcer |
| CN101773607A (en) * | 2009-01-12 | 2010-07-14 | 王栓小 | Gastric ulcer medicament capsule for treating peptic ulcer with deficiency-cold symptoms |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1343508A (en) * | 2001-01-09 | 2002-04-10 | 刘宝泉 | Chinese patent medicine for treating peptic ulcer |
| CN101773607A (en) * | 2009-01-12 | 2010-07-14 | 王栓小 | Gastric ulcer medicament capsule for treating peptic ulcer with deficiency-cold symptoms |
Non-Patent Citations (2)
| Title |
|---|
| 刘建军等: "糜烂性胃炎的中医治疗进展", 《中医药信息》, vol. 23, no. 05, 10 September 2006 (2006-09-10), pages 16 - 18 * |
| 朱瑜瑜等: "朱曙东结合内镜辨证论治慢性萎缩性胃炎之经验", 《辽宁中医药大学学报》, vol. 13, no. 01, 31 January 2011 (2011-01-31), pages 149 - 150 * |
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