CN103006315B - Freezing-heating tool - Google Patents

Freezing-heating tool Download PDF

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Publication number
CN103006315B
CN103006315B CN201310007889.1A CN201310007889A CN103006315B CN 103006315 B CN103006315 B CN 103006315B CN 201310007889 A CN201310007889 A CN 201310007889A CN 103006315 B CN103006315 B CN 103006315B
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liquid nitrogen
tool
cold
thermocouple
cutter
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CN201310007889.1A
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CN103006315A (en
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赵刚
朱凯旋
高大勇
邱本胜
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University of Science and Technology of China USTC
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University of Science and Technology of China USTC
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Abstract

The invention discloses a freezing-heating tool which comprises a body, a heat insulating jacket, a tool bit, a first thermocouple, a radio-frequency hyperthermia antenna, a liquid nitrogen tube, a liquid nitrogen nozzle and a gas backflow cavity, wherein the body consists of a tool handle, a tool rod and a tool shell. The tool shell peripherally surrounds the tool rod and the tool bit, one end of the tool rod is connected with the tool handle, and the other end of the tool rod is connected with the tool bit. The liquid nitrogen tube is positioned in the tool rod, one end of the liquid nitrogen nozzle is connected with the liquid nitrogen tube, and the other end of the liquid nitrogen nozzle is positioned in the tool bit. The heat insulating jacket is inlayed to the inner periphery of a non-therapeutic section of the tool rod, a free space formed by the liquid nitrogen tube and the heat insulating jacket inlayed to the inner periphery of the tool rod is the gas backflow cavity, a part of the radio-frequency hyperthermia antenna penetrates out of the tool bit, and the first thermocouple is arranged in the tool bit. Using the freezing-heating tool for surgeries is small in surgical trauma, free of side effects and low in cost, and patients can recover quickly, do not need to be hospitalized, and can leave as long as treatment is completed.

Description

A kind of cold and hot cutter
Technical field
The present invention relates to technical field of medical instruments, more particularly, relate to a kind of cold and hot cutter.
Background technology
At present, the living environment of people constantly worsens, and the sickness rate of malignant tumor improves constantly, and presents the trend of rejuvenation.Traditional excision, wound is large, and hemorrhage many, patient recovers slow, and the hospital stays is long.Normal cell and immunocyte, while killing and wounding cancerous cell, are also together killed by radiation and chemotherapy.Traditional remedies not only success rate is not high, and has a strong impact on the orthobiosis of patient, most people's disability.
Summary of the invention
In view of this, the invention provides a kind of cold and hot cutter, to realize reducing the wound to patient, and be applicable to the tumor for the treatment of different times.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of cold and hot cutter, comprising: the body be made up of handle of a knife, knife bar and cutter shell, jacket, cutter head, the first thermocouple, radio-frequency (RF) thermotherapeutic antenna, liquid nitrogen pipe, liquid nitrogen nozzle and gas back cavity; Wherein:
Described cutter girdle is around in the periphery of described knife bar and described cutter head;
Described knife bar one end is connected with described handle of a knife, and the other end is connected with described cutter head;
Described liquid nitrogen pipe is positioned at described knife bar;
Described liquid nitrogen nozzle one end is connected with described liquid nitrogen pipe, and the other end is positioned at described cutter head;
Described jacket is embedded in described knife bar non-treatment section and encloses;
Described liquid nitrogen pipe and described to be embedded in the free space that the jacket that encloses in described knife bar formed be gas backstreaming chamber;
Described radio-frequency (RF) thermotherapeutic antenna passes a part from described cutter head;
Described first thermocouple is arranged in described cutter head.
Preferably, described cold and hot cutter also comprises the second thermocouple and heater strip; Wherein:
Described second thermocouple is located on described jacket;
Described heater strip is embedded in the periphery of described jacket.
Preferably, described liquid nitrogen pipe is one or more.
Preferably, described liquid nitrogen pipe is titanium alloy tube.
Preferably, described handle of a knife is made up of politef or acrylonitrile-butadiene-styrene copolymer.
Preferably, described radio-frequency (RF) thermotherapeutic antenna is made up of titanium alloy or copper alloy.
As can be seen from above-mentioned technical scheme, the cold and hot cutter of one disclosed by the invention, by adopting radio-frequency (RF) thermotherapeutic antenna, tumor tissues is heated, compared with heating with traditional helium, radio-frequency (RF) thermotherapeutic antenna can be heated to higher temperature tumor tissues, and due to the wavelength of radio-frequency (RF) thermotherapeutic antenna longer, to tissue penetration capacity strong, heat can penetrate into darker tumor tissues, therefore, it is possible to play better therapeutic effect; Simultaneously; when adopting liquid nitrogen to carry out cold therapy to tumor tissues; jacket is inlayed by enclosing in knife bar in the non-treatment section of cold and hot cutter; effectively can reduce the heat exchange of liquid nitrogen pipe and knife bar periphery; thus effectively decrease the gasification that liquid nitrogen arrives effectively treatment section; also protect and organize not frost bitten around cold and hot cutter non-treatment section, make the wound of performing the operation little, have no side effect, expense is low, recoverys is fast, without the need in hospital, can with controlling with walking.
Accompanying drawing explanation
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, be briefly described to the accompanying drawing used required in embodiment or description of the prior art below, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
The structural representation of Fig. 1 a kind of cold and hot cutter disclosed in the embodiment of the present invention;
The structural representation of Fig. 2 a kind of cold and hot cutter disclosed in another embodiment of the present invention.
Detailed description of the invention
Below in conjunction with the accompanying drawing in the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only a part of embodiment of the present invention, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
The embodiment of the invention discloses a kind of cold and hot cutter, to realize reducing the wound to patient, and be applicable to the tumor for the treatment of different times.
As shown in Figure 1, a kind of cold and hot cutter, comprising: the body be made up of handle of a knife 101, knife bar 102 and cutter shell 103, jacket 104, cutter head 105, first thermocouple 106, radio-frequency (RF) thermotherapeutic antenna 107, liquid nitrogen pipe 108, liquid nitrogen nozzle 109 and gas back cavity 110; Wherein:
Cutter shell 103 is surrounded on the periphery of knife bar 102 and cutter head 105;
Knife bar 102 one end is connected with handle of a knife 101, and the other end is connected with cutter head 105;
Liquid nitrogen pipe 108 is positioned at knife bar 102;
Liquid nitrogen nozzle 109 one end is connected with liquid nitrogen pipe 108, and the other end is positioned at cutter head 105;
Jacket 104 is embedded in knife bar 102 non-treatment section and encloses;
Liquid nitrogen pipe 108 is gas backstreaming chamber 110 with being embedded in the free space that the jacket 104 that encloses in knife bar 102 formed;
Radio-frequency (RF) thermotherapeutic antenna 107 passes a part from cutter head 105;
First thermocouple 106 is arranged in cutter head 105.
Concrete, the liquid nitrogen pipe in cold and hot cutter can be one also can be more than one.
Concrete, liquid nitrogen pipe is titanium alloy tube.
Concrete, handle of a knife is made up of politef or acrylonitrile-butadiene-styrene copolymer.
Concrete, radio-frequency (RF) thermotherapeutic antenna is made up of titanium alloy or copper alloy.
In the above-described embodiments, when carrying out cold treatment, start liquid nitrogen and flow to liquid nitrogen nozzle 109 by liquid nitrogen pipe 108, liquid nitrogen is sprayed onto gas backstreaming chamber 110 by liquid nitrogen nozzle 109, and liquid nitrogen gasifies rapidly, and nitrogen is flowed back to by gas backstreaming chamber 110.Because the nitrogen temperature after gasification is very low, effective treatment section (insulated in knife bar overlap the part of inlaying) is generally refrigerated to less than-190 DEG C within 5-30 second, therefore, tissue near effective treatment section is rapidly frozen, and constantly carrying out along with cold treatment process, ice hockey is constantly grown up (ice hockey is axially outer centered by the effective section for the treatment of generation).The temperature of the feedback point of a knife that the first thermocouple 106 built-in in cutter head 105 is real-time, thus can be real-time cold treatment process is controlled.
When carrying out thermotherapy, the longer rf wave of wavelength is sent to top at cold and hot cutter by radio-frequency (RF) thermotherapeutic antenna 107, excite the tumor tissues intermediate ion concussion heat production of surrounding, raise the temperature to the temperature (minimum temperature killing malignant cell is 42 DEG C) of effectively killing tumor cell, and keep a period of time.The temperature of the feedback point of a knife that the first thermocouple 106 built-in in cutter head 105 is real-time, thus can be real-time cold treatment process is controlled.
As shown in Figure 2, another embodiment of the present invention also discloses a kind of cold and hot cutter, comprising: the body be made up of handle of a knife 201, knife bar 202 and cutter shell 203, jacket 204, cutter head 205, first thermocouple 206, radio-frequency (RF) thermotherapeutic antenna 207, liquid nitrogen pipe 208, liquid nitrogen nozzle 209, gas backstreaming chamber 210, second thermocouple 211 and heater strip 212; Wherein:
Cutter shell 203 is surrounded on the periphery of knife bar 202 and cutter head 205;
Knife bar 202 one end is connected with handle of a knife 201, and the other end is connected with cutter head 205;
Liquid nitrogen pipe 208 is positioned at knife bar 202;
Liquid nitrogen nozzle 209 one end is connected with liquid nitrogen pipe 208, and the other end is positioned at cutter head 205;
Jacket 204 is embedded in knife bar 202 non-treatment section and encloses;
Liquid nitrogen pipe 208 is gas backstreaming chamber 210 with being embedded in the free space that the jacket 204 that encloses in knife bar 202 formed;
Radio-frequency (RF) thermotherapeutic antenna 207 passes a part from cutter head 205;
First thermocouple 206 is arranged in cutter head 205;
Second thermocouple 211 is located on jacket 204;
Heater strip 212 is embedded in the periphery of jacket 204.
Concrete, the liquid nitrogen pipe in cold and hot cutter can be one also can be more than one.
Concrete, liquid nitrogen pipe is titanium alloy tube.
Concrete, handle of a knife is made up of politef or acrylonitrile-butadiene-styrene copolymer.
Concrete, radio-frequency (RF) thermotherapeutic antenna is made up of titanium alloy or copper alloy.
In the above-described embodiments, when carrying out cold treatment, start liquid nitrogen and flow to liquid nitrogen nozzle 209 by liquid nitrogen pipe 208, liquid nitrogen is sprayed onto gas backstreaming chamber 210 by liquid nitrogen nozzle 209, and liquid nitrogen gasifies rapidly, and nitrogen is flowed back to by gas backstreaming chamber 210.Because the nitrogen temperature after gasification is very low, effective treatment section (insulated in knife bar overlap the part of inlaying) is generally refrigerated to less than-190 DEG C within 5-30 second, therefore, tissue near effective treatment section is rapidly frozen, and constantly carrying out along with cold treatment process, ice hockey is constantly grown up (ice hockey is axially outer centered by the effective section for the treatment of generation).The temperature of the feedback point of a knife that the first thermocouple 206 built-in in cutter head 205 is real-time, thus can be real-time cold treatment process is controlled.
When carrying out thermotherapy, the longer rf wave of wavelength is sent to top at cold and hot cutter by radio-frequency (RF) thermotherapeutic antenna 207, excite the tumor tissues intermediate ion concussion heat production of surrounding, raise the temperature to the temperature (minimum temperature killing malignant cell is 42 DEG C) of effectively killing tumor cell, and keep a period of time.The temperature of the feedback point of a knife that the first thermocouple 206 built-in in cutter head 205 is real-time, thus can be real-time cold treatment process is controlled.
Cold and hot cutter disclosed by the invention other knife bar 202 part except treatment section is all inlaid with jacket 204, and on jacket 204, be provided with the second thermocouple 211, is inlaid with heater strip 212 in the periphery of jacket 204.When treating, the temperature that can gather according to the second thermocouple 211 regulates the heat compensation amount of heater strip 212 in real time, makes the non-treatment section of cold and hot cutter periphery can maintain certain temperature, thus protection normal structure not frost bitten.
Cold and hot cutter disclosed by the invention can work under nuclear magnetic resonance imaging system (MRI) guiding in real time, and because nuclear magnetic resonance, NMR dynamic is observed, imaging there is not artifact and resolution is high, can show structure clearly especially to soft tissue.Therefore, over the course for the treatment of, cold and hot cutter disclosed by the invention can accurate targeting destroyed tumor tissue.Such as, when carrying out cold treatment, when nuclear magnetic resonance imaging system monitor ice hockey surround whole tumor tissues time, then control cold and hot cutter and stop cold treatment process.
In this description, each embodiment adopts the mode of going forward one by one to describe, and what each embodiment stressed is the difference with other embodiments, between each embodiment identical similar portion mutually see.
To the above-mentioned explanation of the disclosed embodiments, professional and technical personnel in the field are realized or uses the present invention.To be apparent for those skilled in the art to the multiple amendment of these embodiments, General Principle as defined herein can without departing from the spirit or scope of the present invention, realize in other embodiments.Therefore, the present invention can not be restricted to these embodiments shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.

Claims (5)

1. a cold and hot cutter, is characterized in that, comprising: the body be made up of handle of a knife, knife bar and cutter shell, jacket, cutter head, the first thermocouple, radio-frequency (RF) thermotherapeutic antenna, liquid nitrogen pipe, liquid nitrogen nozzle and gas back cavity; Wherein:
Described cutter girdle is around in the periphery of described knife bar and described cutter head;
Described knife bar one end is connected with described handle of a knife, and the other end is connected with described cutter head;
Described liquid nitrogen pipe is positioned at described knife bar;
Described liquid nitrogen nozzle one end is connected with described liquid nitrogen pipe, and the other end is positioned at described cutter head;
Described jacket is embedded in described knife bar non-treatment section and encloses;
Described liquid nitrogen pipe and described to be embedded in the free space that the jacket that encloses in described knife bar formed be gas backstreaming chamber;
Described radio-frequency (RF) thermotherapeutic antenna passes a part from described cutter head;
Described first thermocouple is arranged in described cutter head;
Also comprise the second thermocouple and heater strip; Wherein:
Described second thermocouple is located on described jacket;
Described heater strip is embedded in the periphery of described jacket.
2. cold and hot cutter according to claim 1, is characterized in that, described liquid nitrogen pipe is one or more.
3. cold and hot cutter according to claim 2, is characterized in that, described liquid nitrogen pipe is titanium alloy tube.
4. cold and hot cutter according to claim 3, is characterized in that, described handle of a knife is made up of politef or acrylonitrile-butadiene-styrene copolymer.
5. cold and hot cutter according to claim 4, is characterized in that, described radio-frequency (RF) thermotherapeutic antenna is made up of titanium alloy or copper alloy.
CN201310007889.1A 2013-01-09 2013-01-09 Freezing-heating tool Active CN103006315B (en)

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Citations (10)

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CN1561925A (en) * 2004-04-22 2005-01-12 上海交通大学 Needle type cold and hot alternative tumor therapeutic head
CN2713992Y (en) * 2004-07-28 2005-08-03 上海靶向医疗系统有限公司 Comprehensive target therapy platform for human body tumor treatment
CN1812748A (en) * 2003-06-25 2006-08-02 恩道凯尔公司 Detachable cryosurgical probe
CN101209217A (en) * 2006-12-26 2008-07-02 上海导向医疗系统有限公司 Gas throttling cooling type radio frequency ablation electrode
CN101579256A (en) * 2008-05-13 2009-11-18 上海导向医疗系统有限公司 Concentric, detachable and replaceable multifunctional targeted tumor scalpel
CN101803947A (en) * 2010-03-11 2010-08-18 中国科学院理化技术研究所 Cold and hot probe device for tumor cold and hot combined treatment
CN202044338U (en) * 2011-02-14 2011-11-23 中国科学院理化技术研究所 Self-maintaining type integration cold and hot sword device for tumour treatment
CN102631245A (en) * 2011-02-14 2012-08-15 中国科学院理化技术研究所 Surgical robot system for cutting frozen tumor tissue by laser
CN102784004A (en) * 2012-02-23 2012-11-21 中国人民解放军第三军医大学第一附属医院 Liquid nitrogen minimally-invasive cold knife

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US7097641B1 (en) * 1999-12-09 2006-08-29 Cryocath Technologies Inc. Catheter with cryogenic and heating ablation
CN2579358Y (en) * 2002-11-25 2003-10-15 罗昌渠 Controllable radio frequency cold and heat pole
US20090005766A1 (en) * 2007-06-28 2009-01-01 Joseph Brannan Broadband microwave applicator
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Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2458995Y (en) * 2001-01-20 2001-11-14 中国科学院理化技术研究所 Immersion cooling type cold knife device capable of promoting quick temperature rise and melting of frozen tumor tissue
CN1812748A (en) * 2003-06-25 2006-08-02 恩道凯尔公司 Detachable cryosurgical probe
CN1561925A (en) * 2004-04-22 2005-01-12 上海交通大学 Needle type cold and hot alternative tumor therapeutic head
CN2713992Y (en) * 2004-07-28 2005-08-03 上海靶向医疗系统有限公司 Comprehensive target therapy platform for human body tumor treatment
CN101209217A (en) * 2006-12-26 2008-07-02 上海导向医疗系统有限公司 Gas throttling cooling type radio frequency ablation electrode
CN101579256A (en) * 2008-05-13 2009-11-18 上海导向医疗系统有限公司 Concentric, detachable and replaceable multifunctional targeted tumor scalpel
CN101803947A (en) * 2010-03-11 2010-08-18 中国科学院理化技术研究所 Cold and hot probe device for tumor cold and hot combined treatment
CN202044338U (en) * 2011-02-14 2011-11-23 中国科学院理化技术研究所 Self-maintaining type integration cold and hot sword device for tumour treatment
CN102631245A (en) * 2011-02-14 2012-08-15 中国科学院理化技术研究所 Surgical robot system for cutting frozen tumor tissue by laser
CN102784004A (en) * 2012-02-23 2012-11-21 中国人民解放军第三军医大学第一附属医院 Liquid nitrogen minimally-invasive cold knife

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