CN102988845A - Chinese medicine composition for treating hyperplasia of prostate and preparation method of Chinese medicine composition - Google Patents

Chinese medicine composition for treating hyperplasia of prostate and preparation method of Chinese medicine composition Download PDF

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CN102988845A
CN102988845A CN2012104063250A CN201210406325A CN102988845A CN 102988845 A CN102988845 A CN 102988845A CN 2012104063250 A CN2012104063250 A CN 2012104063250A CN 201210406325 A CN201210406325 A CN 201210406325A CN 102988845 A CN102988845 A CN 102988845A
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CN102988845B (en
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潘根起
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He Yansheng
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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and in particular discloses a Chinese medicine composition for treating hyperplasia of prostate and a preparation method of the Chinese medicine composition. The Chinese medicine composition is prepared from the following Chinese medicinal herbs in parts by weight: 5-10 parts of fried rhizoma atractylodis, 5-10 parts of amur cork tree bark, 5-15 parts of cortex mori radicis, 10-15 parts of plantain seed, 3-10 parts of parched pangolin, 3-10 parts of common burreed rhizome, 5-10 parts of fired semen vaccariae, 5-15 parts of lumbricus, 3-9 parts of safflower, 5-15 parts of Chinese angelica, 6-15 parts of medicinal cyathula root, 1.5-3 parts of amber, 10-60 parts of astragalus, 5-10 parts of ginseng, 3-15 parts of radix aconiti lateralis preparata and 5-10 parts of pulp of dogwood fruit. The Chinese medicine composition has the effects of clearing heat, promoting dieresis, nourishing qi, warming kidney, resolving hard lump, and dispersing blood stasis, and has quick treatment effect on the hyperplasia of prostate with definite treatment effect.

Description

A kind of Chinese medicine composition and preparation method for the treatment of hyperplasia of prostate
Technical field
The invention belongs to technical field of Chinese medicines, particularly a kind of Chinese medicine composition and preparation method for the treatment of hyperplasia of prostate.
Background technology
Hyperplasia of prostate belongs to motherland's medical science " difficulty in urination " category, now is referred to as " essence is infirmity ".Wherein with dysuria, drop and be short of, the slow person of patient's condition is " infirmity "; , patient's condition more anxious person obstructed take the obturation of urinating, drop is as " closing ".Because the two all refers to dysuria, only have the difference of degree, therefore, be collectively referred to as " difficulty in urination " more.Its etiology and pathogenesis is: because of urine unobstructed, depend on kidney and bladder and qiactivity of triple energizer and lung, spleen, kidney logical accent, transmit, evaporate.Therefore the generation of primary disease how with age asthenia of renal qi, make great efforts to bear a heavy burden, exhaustion due to sexual indulgence is done one's utmost, surfeit is pungent, blood stasis bladder etc. causes disturbance in functioning of QI and the impairment of purifying and descending function of the lung of kidney and bladder and three warmers, can not regulating fluid apssage; Spleen is lost defeated, can not ascending the clear and descending the turbid; Kidney loses and evaporates, and the folding of closing the door is unfavorable; Depression of liver-QI causes stagnation of QI-blood, urethral obstruction; Damp invasion of lower energizer, cannot not pent up loosely, the stasis blocking part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels etc. affects the gasification of three warmers, causes frequent micturition, the nocturia increased frequency, dysuria, perineum, lower abdominal distention pain, and acute urine retention or urinary incontinence, even impaired renal function appears, western medicine: to the dysuria that prostatic hyperplasia causes, use the antibacterial drug therapy weak effect; With phenoxybenzamine or finasteride treatment, side effect is more; Though and urethral catheterization can be alleviated the matter of great urgency, easily cause urethra wound, hyperemia, swelling, more weighting lined urine difficulty; Its operative treatment is easily recurrence again.
Summary of the invention
For overcoming the deficiencies in the prior art part, the object of the present invention is to provide a kind of Chinese medicine composition for the treatment of hyperplasia of prostate, for achieving the above object, the technical scheme that the present invention takes is as follows:
A kind of Chinese medicine composition for the treatment of hyperplasia of prostate is characterized in that: each crude drug by following portions by weight is made: Rhizoma Atractylodis (parched) 5-10 part Cortex Phellodendri 5-10 part Cortex Mori 5-15 part Semen Plantaginis 10-15 part Squama Manis preparata 3-10 part rhizoma sparganic 3-10 part Semen Vaccariae (parched) 5-10 part Pheretima 5-15 part Flos Carthami 3-9 part Radix Angelicae Sinensis 5-15 part Radix Cyathulae 6-15 part succinum 1.5-3 part Radix Astragali 10-60 part Radix Ginseng 5-10 part Radix Aconiti Lateralis Preparata 3-15 part Fructus Corni 5-10 part.
The parts by weight of described each crude drug are preferably: Rhizoma Atractylodis (parched) 6-10 part Cortex Phellodendri 6-10 part Cortex Mori 8-15 part Semen Plantaginis 10-12 part Squama Manis preparata 5-8 part rhizoma sparganic 6-10 part Semen Vaccariae (parched) 8-10 part Pheretima 8-15 part Flos Carthami 6-9 part Radix Angelicae Sinensis 8-15 part Radix Cyathulae 8-15 part succinum 1.5-2 part Radix Astragali 20-60 part Radix Ginseng 8-10 part Radix Aconiti Lateralis Preparata 8-15 part Fructus Corni 8-10 part.
Important umber the best of described each crude drug is elected as: 10 parts of 10 parts of Fructus Corni of 10 parts of Radix Aconiti Lateralis Preparata of 30 parts of Radix Ginsengs of 1.5 parts of Radixs Astragali of 10 parts of succinums of 10 portions of Radix Cyathulaes of 9 parts of Radix Angelicae Sinensis of 10 parts of Flos Carthamis of 10 parts of Pheretimas of 10 parts of Semen Vaccariae (parched)s of 5 parts of rhizoma sparganic of 10 parts of Squama Manis preparatas of 15 portions of Semen Plantaginiss of 10 parts of Cortex Mori of 10 portions of Cortex Phellodendris of Rhizoma Atractylodis (parched).
Described Chinese medicine composition is: make any clinically acceptable preparation according to existing technique.
Described preparation is: decoct, granule, pill or capsule etc.
Acute stage: with decoct or granule,
The preparation method of described Chinese medicine composition decoct is put into marmite with the Chinese medicine composition of described weight portion, and first fries in shallow oil the water that adds 500-700 parts by volume, soaks 20-40 minute, after boiling with high heat first, uses 25-35 at a simmer minute, taking liquid again; Second fries in shallow oil and adds, and the water of 400-600 parts by volume after boiling with high heat first, is used 20-30 at a simmer minute, taking liquid again; Merge twice medicinal liquid.The unit of described weight portion is in g, and the unit of parts by volume is in ml.The two at twice clothes of boiling medicine behind the liquid mixing, morning and evening service once, decoction being taken warmly.
The preparation method of described Chinese medicinal composition granules uses the decoction of existing technique, concentrated, dry, granulation supervisor to be refined into granule the Chinese medicine composition of described weight portion, the pack sealing, and every bag of 10g each serving 1 bag, takes three times every day.
The stable disease phase: with pill or capsule,
The preparation method of described Chinese medicine composition honeyed pill after the Chinese medicine composition pulverizing with described weight portion, is crossed 100 orders or 120 mesh sieves and is made superfine medicated powder, again medicated powder and honey is made honeyed pill by the weight ratio of 1:1.2-1.8, every ball 3g, and each serving 6g, every twice-daily.
The preparation method of described Chinese medicinal composition capsules agent after the Chinese medicine composition of described weight portion pulverized, is crossed 100 orders or 120 mesh sieves and is made superfine medicated powder, and with the medicated powder Capsules of packing into, every 0.3g each serving 6, takes three times every day.
This Chinese medicine composition is bright to have: clearing away heat-damp and promoting diuresis, QI invigorating the kidney warming, hard masses softening and resolving, blood stasis dispelling be logical the effect such as to close.
The pharmacology of each crude drug of the present invention is as follows:
Rhizoma Atractylodis: hot, bitter, warm.Return spleen, stomach warp.Has merit drying damp and strengthening spleen, wind-damp dispelling.The kind dry spleen of this product is wet, and to retention of dampness in middle-JIAO, dysfunction of the spleen in transportation, the card that causes retention of water-damp in the body is especially suitable.Get this product at this drying damp and strengthening spleen.The power that compatibility Radix Ginseng, the Radix Astragali strengthen invigorating the spleen and benefiting QI and have under one's command makes functioning of bladder, constraint normally, the water channel tonneau.
Cortex Phellodendri: bitter, cold.Return kidney, bladder, large intestine channel.Have heat clearing away, dampness, eliminating fire and detoxication, bring down a fever except the merit of steaming.The sedimentation of this product bitter cold, heat clearing and damp drying is longer than and is rushed down clearly damp-heat in lower-JIAO, is used for damp-heat flowing down to the urinary bladder, burning sensation during urination, the diseases such as odynuria.
Cortex Mori: sweet, cold.Return lung meridian.Merit with eliminating pathogen from the lung for relieving asthma, inducing diuresis to remove edema.Diuretic can fall clearly lung qi, regulating fluid apssage and in this product.Water channel leads to and normal urination.
Semen Plantaginis: sweet, cold.Return kidney, liver, lung meridian.Merit with inducing diuresis for treating stranguria syndrome, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat from the lung and dissipating phlegm.Sweet and the sliding profit of this product, cold and cool heat clearing away have diuresis inducing function.To damp-heat flowing down to the urinary bladder, and it is particularly suitable to cause the puckery pain person of dribbling urination.
Squama Manis: salty, be slightly cold.Return liver, stomach warp.Has the Xiao of invigorating blood circulation Disorder, the merit of collateral dredging, stimulating milk secretion, detumescence and apocenosis.This moral character is apt to away alter.In reach the internal organs meridians, the stasis of blood of can promoting the circulation of blood dividing stagnates and the mass in the abdomen that disappears, qualcomm meridian, compatibility rhizoma sparganic increase the power of the Disorder hard masses softening and resolving that disappears by force.Can this product be main also, control prostatitis hypertrophy disease.
Rhizoma sparganic: bitter, hot, flat.Return liver, spleen channel.Merit with removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.The hot loose hardship of this product is let out, temperature is logical, can removing blood stasis, and again can promoting the circulation of QI to relieve pain.But the power of removing blood stasis is better than dispelling the stagnated QI.Wang Haogu: " rhizoma sparganic, the gas in the removing blood stasis, Liver Channel blood system medicine are also.Rhizoma sparganic, Rhizoma Curcumae are controlled the long-pending hard person of piece skin ulcer, be hard masses should be resolved gradually also." prostate is the genus of the cloudy Liver Channel of fainting.Therefore use this product to be to cut the usefulness of hard eliminating stagnation.
Semen Vaccariae: bitter, flat.Return liver, stomach warp.Have promoting blood circulation to restore menstrual flow, stimulating milk secretion, eliminating carbuncle, inducing diuresis for treating stranguria syndrome.Control prostatitis with this product compatibility Flos Carthami in recent years.
Pheretima: salty, cold.Return liver, spleen, bladder footpath.Have heat clearing away, the endogenous wind stopping collateral dredging is relievingd asthma, the merit of diuresis.This product has the effect of heat clearing away knot, dredging water passages.Can be used for the cards such as accumulation of heat in the urinary bladder, dysuria or urine retention be obstructed.
Flos Carthami: hot, warm.GUIXIN, liver footpath.Merit with promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.Blood system is led to, specially entered to the hot loose temperature of this product, energy blood circulation promoting and blood stasis dispelling Xiao Disorder, unobstructed blood vessels, reducing swelling and alleviating pain.Compatibility rhizoma sparganic, Squama Manis , Xiao mass in the abdomen, hard masses softening and resolving effect are more excellent.
Radix Angelicae Sinensis: sweet, hot, warm.Return liver, the heart, spleen channel.Have enrich blood, invigorate blood circulation, the merit of regulating menstruation, pain relieving, intestine moistening.The sweet Wen Zhirun of this product is the key medicine of enriching blood.Can the promoting blood circulation and detumescence pain relieving, again can tonic blood and growing muscle.But compatibility Flos Carthami promoting tissue regeneration by removing blood stasis.Join Radix Ginseng, Radix Astragali enhancing vigorate qi and replenish the blood function.
Radix Cyathulae: bitter, sweet, sour, flat.Return liver, kidney channel.Has promoting blood circulation to restore menstrual flow, invigorating the liver and kidney, bone and muscle strengthening, relieving stranguria by diuresis, (blood) the descending merit of igniting.This moral character is kind descending, and the energy relieving stranguria by diuresis can draw again the descending through sick institute of all medicines.
Succinum: sweet, flat.GUIXIN, liver, urinary bladder channel.Have tranquillizing the mind by relieving convulsion, promoting blood circulation to remove blood stasis, the merit of inducing diuresis for treating stranguria syndrome.This product enters the conscience blood system, and promoting blood circulation to restore menstrual flow is arranged, and loose Yu Xiao Disorder effect again can inducing diuresis for treating stranguria syndrome, therefore with the card of controlling stranguria frequent micturition, dysurea and difficulty in urination dysuria.
The Radix Astragali: sweet, tepor.Return spleen, lung meridian.Have: tonifying Qi and lifting yang, benefit are defended the merit of consolidating superficial resistance, inducing diuresis to remove edema, holder skin ulcer granulation promoting.This product can invigorating middle warmer gas, to strengthen the spleen transmitting and distributing the fluids.Again can tonifying the lung gas, with regulating fluid apssage.Therefore be used for the wet dysuria etc. that loses due to the fortune of deficiency of vital energy water.The compatibility Radix Angelicae Sinensis strengthens the power of qi-supplementing, blood-engendering.
Radix Ginseng: sweet, little hardship, tepor.GUIXIN, lung, spleen channel.Has strongly invigorating primordial QI, invigorating the spleen to benefit the lung, the merit of promoting the production of body fluid and inducing sedation of the mind.This product is strongly invigorating primordial QI both, and gas that again can the spleen reinforcing lung has the merit of tonifying five ZANG-organs.Because suffering from for many years high renal failure of hyperplasia of prostate person, therefore insufficiency of vital energy and blood is with this product Compatibility with Radix Astragali, Radix Angelicae Sinensis etc., with QI invigorating and blood producing.Make QI and blood vigorous, be of value to the primary disease functional rehabilitation.
Radix Aconiti Lateralis Preparata: hot, sweet, hot.GUIXIN, kidney, spleen channel.Have recuperating depleted YANG and rescuing the patient from collapse, supporing yang benefit fire, the merit of dispersing cold for relieving pain.This product can on help heart-yang, middle warming the spleen sun, lower kidney-replenishing is recuperating depleted YANG and rescuing the patient from collapse the first product medicine.High complement sun is arranged, the effect of boosting source of fire for eliminating abundance of yin.The treatment insufficiency of kidney-YANG, the chills and pain of the waist and kness due to the gate of vitality is on the decline, the diseases such as nocturia.
Fructus Corni: sour, puckery, tepor.Return liver, kidney channel.Have liver and kidney tonifying, the astringent or styptic treatment for spontaneous sweating merit of convergence.This product acid tepor matter profit, it is warm in nature and not dry, mends and not high, can the kidney invigorating and essence nourishing, and again can warming the kidney to activate YANG; Can nourishing YIN again can YANG invigorating, be the key medicine of liver and kidney tonifying.The compatibility Radix Aconiti Lateralis Preparata is controlled insufficiency of kidney-YANG, soreness of the waist and knees, dysuria.
Above all medicine compatibilities gather altogether: clearing away heat-damp and promoting diuresis, QI invigorating the kidney warming, hard masses softening and resolving, blood stasis dispelling be logical the effect such as to close.Be used for the treatment of because making great efforts heavy burden, exhaustion due to sexual indulgence is done one's utmost, pungent and the greasy and surfeit flavour of surfeit, or old spleen, lung, suffer from a deficiency of the kidney and decline, disturbance in functioning of QI, hematogenous blockage and the stasis blocking part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels etc. cause the functional disorder of three warmers and kidney and bladder to cause: frequent micturition, nocturia increased frequency, dysuria, perineum, lower abdominal distention pain is the diseases such as primary symptom person, and acute urine retention or urinary incontinence, determined curative effect.
The specific embodiment:
Below in conjunction with specific embodiment, technical scheme of the present invention is further detailed, but protection scope of the present invention is not limited to this:
Embodiment 1,
5 parts of Rhizoma Atractylodis (parched), 7 parts of Cortex Phellodendris, 5 parts of Cortex Mori, 12 parts of Semen Plantaginiss, 3 parts of Squama Manis preparatas, 7 parts of rhizoma sparganic, 5 parts of Semen Vaccariae (parched)s, 15 parts of Pheretimas, 3 parts on Flos Carthami, 15 parts of Radix Angelicae Sinensis, 6 parts of Radix Cyathulaes, 3 parts of succinums, 10 parts of the Radixs Astragali, 7 parts of Radix Ginsengs, 15 parts of Radix Aconiti Lateralis Preparata, 5 parts of Fructus Corni
Acute stage: with decoct or granule,
The preparation method of described Chinese medicine composition decoct is put into marmite with the Chinese medicine composition of described weight portion, and first fries in shallow oil the water that adds 500-700 parts by volume, soaks 20-40 minute, after boiling with high heat first, uses 25-35 at a simmer minute, taking liquid again; Second fries in shallow oil the water that adds the 400-600 parts by volume, uses 20-30 at a simmer minute, taking liquid after boiling with high heat first again; Merge twice medicinal liquid.The unit of described weight portion is in g, and the unit of parts by volume is in ml.The two at twice clothes of boiling medicine behind the liquid mixing, morning and evening service once, decoction being taken warmly.
The preparation method of described Chinese medicinal composition granules uses the decoction of existing technique, concentrated, dry, granulation supervisor to be refined into granule the Chinese medicine composition of described weight portion, the pack sealing, and every bag of 10g each serving 1 bag, takes three times every day.
The stable disease phase: with pill or capsule,
The preparation method of described Chinese medicine composition honeyed pill was pulverized 100 orders with the Chinese medicine composition of described weight portion or 120 mesh sieves are made superfine medicated powder, again medicated powder and honey was made honeyed pill by the weight ratio of 1:1.2-1.8, every ball 3g, and each serving 6g, every twice-daily.
The preparation method of described Chinese medicinal composition capsules agent is crossed 100 orders after the Chinese medicine composition of described weight portion pulverized or 120 mesh sieves are made superfine medicated powder, and with the medicated powder Capsules of packing into, every 0.3g each serving 6, takes three times every day.
Embodiment 2
10 parts of Rhizoma Atractylodis (parched), 10 parts of Cortex Phellodendris, 15 parts of Cortex Mori, 10 parts of Semen Plantaginiss, 5 parts of Squama Manis preparatas, 10 parts of rhizoma sparganic, 10 parts of Semen Vaccariae (parched)s, 10 parts of Pheretimas, 9 parts on Flos Carthami, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Cyathulaes, 1.5 parts of succinums, 30 parts of the Radixs Astragali, 10 parts of Radix Ginsengs, 10 parts of Radix Aconiti Lateralis Preparata, 10 parts of Fructus Corni
(preparation method and using method are with embodiment 1)
Embodiment 3
7 parts of Rhizoma Atractylodis (parched), 5 parts of Cortex Phellodendris, 10 parts of Cortex Mori, 10 parts of Semen Plantaginiss, 10 parts of Squama Manis preparatas, 3 parts of rhizoma sparganic, 7 parts of Semen Vaccariae (parched)s, 5 parts of Pheretimas, 7 parts on Flos Carthami, 5 parts of Radix Angelicae Sinensis, 15 parts of Radix Cyathulaes, 2 parts of succinums, 60 parts of the Radixs Astragali, 5 parts of Radix Ginsengs, 3 parts of Radix Aconiti Lateralis Preparata, 7 parts of Fructus Corni
(preparation method and using method are with embodiment 1)
Clinical trial:
1,1 physical data:
From year August in January, 2000 to 2012, accept benign prostatic hyperplasia patients screening totally 118 examples for medical treatment.All cases is all made a definite diagnosis through health check-up and B ultrasonic, lab testing, and becomes calculus of urethra and liver, kidney, the serious depleted person of cardiac function without prostatitis adenocarcinoma.Be divided at random: treatment group 59 examples, the age 36---75 years old, average 60.5 years old; Matched group 59 examples, the age 37---72 years old, average 60 years old.Two groups at aspects such as age, the state of an illness all without significant difference (P〉0.05), have comparability.See table 1 for details
Table 1 liang group case ordinary circumstance relatively
Group (example) Mean age (year) 36---50 years old (example) 51---65 years old (example) 66---75 years old (example)
Treatment group 59 60.5 10 31 18
Matched group 59 60 11 33 15
Annotate: two groups are compared P〉0.05
1.2, diagnostic criteria:
1. be more common in the elderly men more than 55 years old; 2, gradual frequent micturition, take night as obviously; 3, dysuria, urine line attenuate; 4, chronic urinary hesitancy; 5, perineum, lower abdominal distention pain; 6, dribbling urination is not well or inaccessible obstructed; 7, B ultrasonic shows: the residual urine of bladder increases, prostate increases.
1.3 Therapeutic Method:
Matched group: adopt the routine of western medicine treatment, with phenoxybenzamine hydrochloride or finasteride etc., use corresponding antibiotic when urinary tract infection is arranged, remaining symptomatic treatment.
Treatment group: treat on the basis with routine of western medicine at matched group, add the embodiment of the invention 2 prescriptions, or take separately the embodiment of the invention 2 prescriptions.
(the same content of its preparation method and using method)
Two groups treated respectively for 3 weeks after, all carry out ultrasound diagnosis before and after two groups of treatments, observe clinical symptoms and improve situation, and compare.
1.4 therapeutic evaluation
1.4.1. produce effects: clinical symptom disappearance, the prostate that B ultrasonic is observed enlargement dwindles〉70%.
1.4.2. effectively: clinical symptoms disappears substantially, B ultrasonic is observed the prostate contracting of enlargement〉50%.
1.4.2. invalid: clinical symptoms is without obvious improvement, and the prostate that B ultrasonic is observed enlargement is without dwindling, even also continues to increase.
1.5. statistical method:
Data represent with rate, adopt the X2 check, take P<0.05 as difference statistical significance are arranged.
1.6. result:
1.6.1. two groups of doing well,improving situations relatively before and after the treatment
Treatment group is treated on the basis with routine of western medicine at matched group, clinical symptoms improvement rate (94%) after adding Chinese medicine composition of the present invention or taking separately traditional Chinese medicine composition for treating of the present invention obviously is better than matched group and takes merely the rear clinical symptoms improvement rate (54%) of routine of western medicine treatment.See table 2 for details.
The table 2. liang forward and backward clinical symptoms of group treatment is improved routine number and improvement rate:
Figure 485897DEST_PATH_IMAGE002
Annotate: improvement=produce effects+effectively
1.6.2. untoward reaction:
It is nauseating, dizzy that matched group has 3 examples to occur.Treatment group has no untoward reaction.
Model case:
Case 1
. Ma, the man, 50 years old, the workman was first villages and small towns worker of staple food control office, the patient before 3 years, without obviously inducement frequent micturition appears, urinate not smooth, the sense of row's urine retention.Once looking into B ultrasonic in the People's Hospital, Nanyue County shows: prostatic hyperplasia is clearly better through the treatment nothing.Every afterwards is that dysuria increases the weight of because drinking or throwing off restraint the pungent product of food.Therefore come the inventor to locate on February 16th, 2011.Disease is seen: urination disorder, obstructed, the little distention and fullness in the abdomen of urine drop, bitter taste, feeling thirst but no desire to drink water, red tongue, yellow and greasy fur, soft and rapid pulse.B ultrasonic shows: prostatic hyperplasia (35 * 43 * 28) mm
Dialectical Analyses: damp and hot Mares-tail amasss in bladder, therefore frequent micturition is unfavorable, drop is obstructed.Damp-heat gluing each other, functioning of bladder are unfavorable, therefore little distention and fullness in the abdomen.Therefore damp and hot interior Sheng is bitter taste.Body fluid is cloth not, therefore thirsty and tending to drink water not.Red tongue, yellow and greasy fur, soft and rapid pulse are levying of damp invasion of lower energizer.
Tcm diagnosis: the difficulty in urination (damp-heat accumulation)
Western medicine diagnose: hyperplasia of prostate
The rule for the treatment of: clearing away heat-damp and promoting diuresis, hard masses softening and resolving, blood stasis dispelling is logical closes.
Side's medicine: the embodiment of the invention 2 prescriptions, method of preparation and use.
Western medicine: prevention urinary system infection Quinolones antibiotic.The dysuria phenoxybenzamine, remaining symptomatic treatment.
After treating for 1 week, dysuria obviously alleviates.Clinical all symptoms also are clearly better.After treating for 3 weeks, the urine number of times is normal, and urinate is than tonneau, and the lower abdomen distension disappears, and bitter taste also disappears, and advises and continues to take 2 weeks to consolidate curative effect.By repeatedly following up a case by regular visits to, so far without repeatedly.
Case 2.
Lee so-and-so, the man, 70 years old, the peasant was south of a town street, area just outside a city gate, Nanyue County people from village, the patient once examined in the People's Hospital, Nanyue County because of dysuria before 10 years and was hyperplasia of prostate, gave the medicine treatments such as phenoxybenzamine, effect is not good enough, and repeatedly outbreak.Therefore come the inventor to locate on November 8th, 2010.Disease is seen: the urine drop is not well, discharges unable, sagging distention in the smaller abdomen, fear of cold, the waist knee joint is cold and aching and limp unable, the complexion Guang is white, look timidity, pale tongue, tongue is white, deep-thready pulse and a little less than.B ultrasonic shows: prostatic hyperplasia (38 * 49 * 30) mm
Dialectical Analyses: decline of the fire from the gate of life, disturbance in functioning of QI, thus urine drop not well, discharge unable, sagging distention in the smaller abdomen.Unit's deficiency of vital energy declines, therefore meeting color Guang is white, and timid and weak mind, fear of cold waist knee joint is cold and aching and limp unable.Pale tongue, tongue is white, deep-thready pulse and a little less than be resembling of insufficiency of kidney-YANG.
Tcm diagnosis: the difficulty in urination (kidney yang deficiency).
Western medicine diagnose: hyperplasia of prostate.
The rule for the treatment of: the QI invigorating the kidney warming, hard masses softening and resolving, blood stasis dispelling is logical closes.
Side's medicine: the embodiment of the invention 2 prescriptions, method of preparation and use.
Western medicine: control and prevention infection ceftriaxone, control dysuria finasteride, remaining symptomatic treatment.
After treating for 2 weeks, the front obviously tonneau of urinating, sagging distention in the smaller abdomen alleviates.After controlling for 4 weeks, dysuria disappears substantially, sagging distention in the smaller abdomen, and fear of cold, the cold and aching and limp unable basic recovery of waist knee joint is normal.Advise and continued to take 2 weeks to consolidate curative effect.By repeatedly following up a case by regular visits to, so far without repeatedly.
Press: hyperplasia of prostate uses merely Western medicine antibiotic or with phenoxybenzamine or finasteride, can only relief of symptoms, but drug withdrawal is namely recurred.And after adding Chinese medicine composition of the present invention, not only control symptom fast, and effect stability is reliable, can long-time relief of symptoms and not repeatedly.
  

Claims (9)

1. Chinese medicine composition and preparation method for the treatment of hyperplasia of prostate, it is characterized in that: each crude drug by following weight/volume parts is made: Rhizoma Atractylodis (parched) 5-10 part Cortex Phellodendri 5-10 part Cortex Mori 5-15 part Semen Plantaginis 10-15 part Squama Manis preparata 3-10 part rhizoma sparganic 3-10 part Semen Vaccariae (parched) 5-10 part Pheretima 5-15 part Flos Carthami 3-9 part Radix Angelicae Sinensis 5-15 part Radix Cyathulae 6-15 part succinum 1.5-3 part Radix Astragali 10-60 part Radix Ginseng 5-10 part Radix Aconiti Lateralis Preparata 3-15 part Fructus Corni 5-10 part.
2. a kind of Chinese medicine composition and preparation method for the treatment of hyperplasia of prostate according to claim 1, it is characterized in that: the weight/volume umber of described each crude drug is preferably: Rhizoma Atractylodis (parched) 6-10 part Cortex Phellodendri 6-10 part Cortex Mori 8-15 part Semen Plantaginis 10-12 part Squama Manis preparata 5-8 part rhizoma sparganic 6-10 part Semen Vaccariae (parched) 8-10 part Pheretima 8-15 part Flos Carthami 6-9 part Radix Angelicae Sinensis 8-15 part Radix Cyathulae 8-15 part succinum 1.5-2 part Radix Astragali 20-60 part Radix Ginseng 8-10 part Radix Aconiti Lateralis Preparata 8-15 part Fructus Corni 8-10 part.
3. a kind of Chinese medicine composition and preparation method for the treatment of hyperplasia of prostate according to claim 1, it is characterized in that: weight/volume umber the best of described each crude drug is elected as: 10 parts of 10 parts of Fructus Corni of 10 parts of Radix Aconiti Lateralis Preparata of 30 parts of Radix Ginsengs of 1.5 parts of Radixs Astragali of 10 parts of succinums of 10 portions of Radix Cyathulaes of 9 parts of Radix Angelicae Sinensis of 10 parts of Flos Carthamis of 10 parts of Pheretimas of 10 parts of Semen Vaccariae (parched)s of 5 parts of rhizoma sparganic of 10 parts of Squama Manis preparatas of 15 portions of Semen Plantaginiss of 10 parts of Cortex Mori of 10 portions of Cortex Phellodendris of Rhizoma Atractylodis (parched).
4. described a kind of Chinese medicine composition and preparation method for the treatment of hyperplasia of prostate one of according to claim 1-3, it is characterized in that: described Chinese medicine composition is: make any clinically acceptable preparation according to existing technique.
5. a kind of Chinese medicine composition and preparation method for the treatment of hyperplasia of prostate according to claim 4, it is characterized in that: described preparation is: decoct, granule, pill or capsule etc.
6. the preparation method of described Chinese medicine composition decoct one of according to claim 1-3, it is characterized in that: the Chinese medicine composition of described weight/volume part is put into marmite, first fries in shallow oil the water that adds 500-700 parts by volume, soaked 20-40 minute, after boiling with high heat first, use again 25-35 at a simmer minute, taking liquid; Second fries in shallow oil the water that adds the 400-600 parts by volume, after boiling with high heat first, uses 20-30 at a simmer minute, taking liquid again; Merge twice medicinal liquid, the unit of described weight portion is in g, and the unit of parts by volume is in ml.
7. the preparation method of described Chinese medicinal composition granules one of according to claim 1-3 is characterized in that: use the decoction of existing technique, concentrated, dry, granulation supervisor to be refined into granule, the pack sealing Chinese medicine composition of described weight/volume part.
8. the preparation method of described Chinese medicine composition honeyed pill one of according to claim 1-3, it is characterized in that: after the Chinese medicine composition of described weight/volume part is pulverized, cross 100 orders or 120 mesh sieves are made superfine medicated powder, again medicated powder and honey are made honeyed pill by the weight ratio of 1:1.2-1.8.
9. the preparation method of described Chinese medicinal composition capsules agent one of according to claim 1-3 is characterized in that: after the Chinese medicine composition of described weight/volume part is pulverized, cross 100 orders or 120 mesh sieves and make superfine medicated powder, with the medicated powder Capsules of packing into.
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