CN102988812B

CN102988812B - Traditional Chinese medicine composition for treating anaphylactic rhinitis

Info

Publication number: CN102988812B
Application number: CN201210558241.9A
Authority: CN
Inventors: 张俊梅; 孟凡玉
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-12-20
Filing date: 2012-12-20
Publication date: 2014-07-30
Anticipated expiration: 2032-12-20
Also published as: CN102988812A

Abstract

The invention discloses a traditional Chinese medicine composition for treating anaphylactic rhinitis, and belongs to the field of traditional Chinese medicines. The composition is prepared from the following raw materials according to parts by weight: 12 parts of flower bud of lily magnolia, 8 parts of loofah sponge, 8 parts of peach kernels, 6 parts of cicada, 6 parts of hives, 8 parts of platycodon grandiflorum, 10 parts of corn stigma, 10 parts of the seeds of Chinese dodder, 8 parts of radish seeds, 12 parts of wild chrysanthemum flowers, 9 parts of kadsura longepedunculata, 8 parts of dayflower, 12 parts of fructus xanthii and 8 parts of cortex lycii radicis. The composition utilizing the nature traditional Chinese medicines as the raw materials can effectively cure the anaphylactic rhinitis without easy relapse due to the cooperative actions of the raw materials. The composition has the advantages of obvious treatment effect and no toxic and side effect. The effective rate reaches 98%.

Description

A kind of Chinese medicine composition for the treatment of of allergic rhinitis

Technical field

The Chinese medicine composition that the present invention relates to a kind for the treatment of of allergic rhinitis, belongs to the field of Chinese medicines.

Background technology

Allergic rhinitis is allergic rhinitis (allergic rhinitis, AR), refer to that the medium (being mainly histamine) mainly being mediated by IgE after atopic individuals contact allergen discharges, and the non-infectious inflammatory diseases of nasal mucosa that has panimmunity competent cell and cytokine etc. to participate in.Allergic rhinitis is a global health problem, can cause numerous disease and labour force to lose.Its basic pathology is changed to telangiectasis, permeability increases and glandular secretion increase and eosinophilic granulocyte infiltration etc.The above-mentioned pathological change catabasis can recover normally, and outbreak repeatedly can cause that mucosal epithelium layer proliferative changes, and causes mucosa plumpness and Polypoid changes.As concurrent infection, can show as glutinous pus tears or pus tears.

The common medicine for the treatment of of allergic rhinitis is generally Western medicine at present, as antihistaminic, glucocorticoid, anti-leukotriene medicine and ketone medicine etc., these medicines conventionally can only relief of symptoms, can not effect a radical cure allergic rhinitis, and this class medicine of long-term taking can produce larger side effect to health.

Summary of the invention

The object of the present invention is to provide a kind of effectively Chinese medicine composition for the treatment of of allergic rhinitis, this Chinese medicine preparation is treatment of allergic rhinitis effectively, determined curative effect and difficult recurrence.

Technical scheme of the present invention is:

A Chinese medicine composition for treatment of allergic rhinitis, is made up of the crude drug of following weight parts: Flos Magnoliae 12, Retinervus Luffae Fructus 8, Semen Persicae 8, Periostracum Cicadae 6, Nidus Vespae 6, Radix Platycodonis 8, Stigma Maydis 10, Semen Cuscutae 10, Semen Raphani 8, Flos Chrysanthemi Indici 12, Fructus Schisandrae Sphenantherae 9, Herba Commelinae 8, Fructus Xanthii 12, Cortex Lycii 8.

Single dose dose (unit: gram): Flos Magnoliae 12, Retinervus Luffae Fructus 8, Semen Persicae 8, Periostracum Cicadae 6, Nidus Vespae 6, Radix Platycodonis 8, Stigma Maydis 10, Semen Cuscutae 10, Semen Raphani 8, Flos Chrysanthemi Indici 12, Fructus Schisandrae Sphenantherae 9, Herba Commelinae 8, Fructus Xanthii 12, Cortex Lycii 8.

Preparation and instructions of taking: be decocted in water for oral dose, every day, potion, divided twice one after each meal sooner or later.

The pharmacological action of each Chinese medicine:

Flos Magnoliae: pungent, temperature.Attach to the lung and stomach meridians.Effect with cure mainly: dispersing wind and cold, clearing the nasal passage.For headche due to wind-cold, nasal obstruction, nasal sinusitis, turbid nasal discharge.

Retinervus Luffae Fructus: sweet, flat.Return lung, stomach, Liver Channel.Effect with cure mainly: dredging collateral, invigorate blood circulation, dispel the wind.For arthralgia pain contracture, distending pain in the chest and hypochondrium, galactostasis.

Semen Persicae: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Effect with cure mainly: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea ， mass in the abdomen mass in the abdomen, injury from falling down, dryness of the intestine constipation.

Periostracum Cicadae: sweet, cold.Return lung, Liver Channel.Effect with cure mainly: loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion buckwheat barrier, convulsion with spasms, tetanus.

Nidus Vespae: sweet, flat.Return stomach warp.Effect with cure mainly: dispel the wind, counteracting toxic substances, parasite killing, pain relieving.In toothache due to dental caries, sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, fungal infection of hand and foot.

Radix Platycodonis: bitter, pungent, flat.Return lung meridian.Effect with cure mainly: lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus.For cough with copious phlegm, uncomfortable in chest not smooth, pharyngalgia, hoarseness, lung abscess vomiting pus, skin infection difficulty in discharging of pus.

Stigma Maydis: sweet, flat.Return bladder, liver, gallbladder meridian.Effect with cure mainly: promoting the function of the gallbladder to alleviate jaundice, diuresis detumescent, hemostasis.Control oedema due to nephritis, beriberi, icterohepatitis, hypertension, cholecystitis, cholelithiasis, diabetes, hematemesis and epistaxis, nasal sinusitis, acute mastitis.

Semen Cuscutae: sweet, temperature.Return liver,kidney,spleen warp.Effect with cure mainly: nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.

Semen Raphani: pungent, sweet, flat.Return lung, spleen, stomach warp.Effect with cure mainly: the de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm.For retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant heap soil or fertilizer over and around the roots is breathed with cough.

Flos Chrysanthemi Indici: bitter, pungent, be slightly cold.Return liver, heart channel.Effect with cure mainly: heat-clearing and toxic substances removing.For furuncle carbuncle, conjunctival congestion and swelling pain.Have a headache dizzy.

Fructus Schisandrae Sphenantherae: sour, sweet, temperature.Return lung, the heart, kidney channel.Effect with cure mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.

Herba Commelinae: sweet, light, cold.Return lung, stomach, small intestine meridian.Effect with cure mainly: heat-clearing and toxic substances removing, inducing diuresis to remove edema.For anemopyretic cold. high hot wood moves back, laryngopharynx swelling and pain, edema oliguria, the puckery pain of pyretic stranguria, carbuncle furunculosis.

Fructus Xanthii: pungent, bitter, temperature; Poisonous.Return lung meridian.Effect with cure mainly: loose wind dehumidifying, clearing the nasal passage.For headche due to wind-cold, nasal sinusitis watery nasal discharge, rubella pruritus, arthralgia chiefly caused by damp pathogen contracture.

Cortex Lycii: sweet, cold.Return lung, liver, kidney channel.Effect with cure mainly: removing heat from blood except steam, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat is quenched one's thirst.

The invention has the beneficial effects as follows: it is raw material that the present invention adopts natural Chinese medicine, between each crude drug, by synergism, effectively cure allergic rhinitis and be difficult for recurrence that determined curative effect and having no side effect can reach 98% by effective percentage.

Below in conjunction with clinical trial and model case, the present invention is further described.

One, clinical trial

1, clinical data: between December to 2011 year December, chose at random Allergic Rhinitis 100 examples of 15～56 years old in 2010, wherein, and male's 47 examples, women's 53 examples, the mean age is 26.4 years old.

2, diagnostic criteria:

(1), clinical symptoms: 2 above (containing 2) appears in the symptoms such as sneeze, clear water sample tears, nasal obstruction, rhinocnesmus, and symptom continued or was accumulated at more than 1 hour every day.Can be with the eye symptom such as ophthalmic pruritus, conjunctival congestion;

(2), anterior rhinoscopy: the pale edema of the visible nasal mucosa of diagnosis of sensitivity rhinitis,, if can there is nasal polyp or polypoid degeneration because of persistency edema in a large amount of clear watery secretion;

(3), nasal secretion plate coating checking: between allergy stage of attack, in nasal discharge, visible eosinophil leucocyte increases, and the diagnosis of sensitivity rhinitis also can be looked into and be seen more eosinophil leucocyte or mastocyte;

(4), allergia provocative test: generally use tuerculoderma (cut, Intradermal and contact method etc.), principle is the allergic effect material that has multiple supposition, after making to contact with body, depending on having or not reaction to occur, can assist diagnosis.After allergen diagnosis is clear and definite, also can apply this allergen and carry out desensitization treatment.

3, Therapeutic Method: treatment group is taken medicine of the present invention, and every day is oral meal at twice, takes one-month period altogether.

4, efficacy assessment standard:

Cure: clinical symptom disappearance, anterior rhinoscopy and nasal secretion plate coating checking are all normal;

Effective: clinical symptoms part disappears, and anterior rhinoscopy and nasal secretion plate coating checking symptom make moderate progress or be tending towards normal;

Invalid: clinical symptoms is without improving or increasing the weight of.

5, therapeutic outcome: at clinical use medicine of the present invention, the 100 routine patients that take medicine, took medicine after 10 days, and symptom is alleviated to some extent, takes medicine after month, and symptom is obviously improved.In the routine patient of clinical trial 100, recovery from illness 76 examples, effective 22 examples, invalid 2 examples, total effective rate is 98%.

Two, model case

Case 1: Wang, man, 25 years old, patient suffered from allergic rhinitis more than 4 years, repeatedly nasal obstruction, rhinorrhea.Must madly sneeze every morning battle array do, after voluntarily medication fail to respond to any medical treatment fruit, repeatedly show effect after 2 years, be still nasal mucus as clear water, seriously nasal obstruction, with headache, often in flu state.Take medicine of the present invention after 15 days, above-mentioned symptom obviously improves, and takes medicine after 1 month, and symptom disappears substantially, after half a year, follows up a case by regular visits to, and the state of an illness is without recurrence.

Case 2: remaining certain, female, 31 years old, suffer from allergic rhinitis 5 years, nasal obstruction rhinocnesmus, sneeze, drops tears, rhinorrhea, dizzy feeling of fullness in the head, the morbidity in spring of being everlasting, hyposmia, has obvious pollen hypersensitivity symptom.Since patient idiopathy, anemophobia is afraid of cold, listlessness, hypomnesis, poor sleep, takes multi-medicament poor effect, after take medicine of the present invention, take medicine after 12 days, symptom is obviously improved, and takes medicine after 1 month, symptom disappears substantially.After 1 year, follow up a case by regular visits to, the state of an illness is without recurrence.

Detailed description of the invention

Embodiment

Proportioning (unit: gram): Flos Magnoliae 12, Retinervus Luffae Fructus 8, Semen Persicae 8, Periostracum Cicadae 6, Nidus Vespae 6, Radix Platycodonis 8, Stigma Maydis 10, Semen Cuscutae 10, Semen Raphani 8, Flos Chrysanthemi Indici 12, Fructus Schisandrae Sphenantherae 9, Herba Commelinae 8, Fructus Xanthii 12, Cortex Lycii 8.

Claims

1. the Chinese medicine composition of a treatment of allergic rhinitis, it is characterized in that, made by the crude drug of following weight parts: Flos Magnoliae 12, Retinervus Luffae Fructus 8, Semen Persicae 8, Periostracum Cicadae 6, Nidus Vespae 6, Radix Platycodonis 8, Stigma Maydis 10, Semen Cuscutae 10, Semen Raphani 8, Flos Chrysanthemi Indici 12, Fructus Schisandrae Sphenantherae 9, Herba Commelinae 8, Fructus Xanthii 12, Cortex Lycii 8.