CN102977188B - Gnrh(促性腺激素释放激素)肽衍生物 - Google Patents
Gnrh(促性腺激素释放激素)肽衍生物 Download PDFInfo
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- CN102977188B CN102977188B CN201210447203.6A CN201210447203A CN102977188B CN 102977188 B CN102977188 B CN 102977188B CN 201210447203 A CN201210447203 A CN 201210447203A CN 102977188 B CN102977188 B CN 102977188B
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (7)
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| US80504206P | 2006-06-16 | 2006-06-16 | |
| US60/805,042 | 2006-06-16 | ||
| US80518106P | 2006-06-19 | 2006-06-19 | |
| US60/805,181 | 2006-06-19 | ||
| GB0616111.1 | 2006-08-12 | ||
| GBGB0616111.1A GB0616111D0 (en) | 2006-06-16 | 2006-08-12 | Agents, methods and uses |
| CN200780026537.3A CN101553500B (zh) | 2006-06-16 | 2007-05-01 | Gnrh(促性腺激素释放激素)肽衍生物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200780026537.3A Division CN101553500B (zh) | 2006-06-16 | 2007-05-01 | Gnrh(促性腺激素释放激素)肽衍生物 |
Publications (2)
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|---|---|
| CN102977188A CN102977188A (zh) | 2013-03-20 |
| CN102977188B true CN102977188B (zh) | 2015-07-15 |
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|---|---|---|---|
| CN201210447203.6A Expired - Fee Related CN102977188B (zh) | 2006-06-16 | 2007-05-01 | Gnrh(促性腺激素释放激素)肽衍生物 |
| CN200780026537.3A Expired - Fee Related CN101553500B (zh) | 2006-06-16 | 2007-05-01 | Gnrh(促性腺激素释放激素)肽衍生物 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200780026537.3A Expired - Fee Related CN101553500B (zh) | 2006-06-16 | 2007-05-01 | Gnrh(促性腺激素释放激素)肽衍生物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9388216B2 (enExample) |
| EP (1) | EP2029618B1 (enExample) |
| JP (2) | JP5290163B2 (enExample) |
| CN (2) | CN102977188B (enExample) |
| GB (1) | GB0616111D0 (enExample) |
| WO (1) | WO2007144554A2 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101864398B (zh) * | 2009-09-03 | 2012-11-14 | 李吉祐 | 一种抗促性腺激素释放激素受体的单克隆抗体与应用 |
| US20120004182A1 (en) * | 2010-07-02 | 2012-01-05 | Carsten Gruendker | Pharmaceutical compositions and methods for induction and enhancement of apoptosis in tumor cells |
| EP2447276A1 (en) * | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| CN102675420B (zh) * | 2011-03-17 | 2014-08-27 | 屏东科技大学 | 一种促进鱼类卵黄生成的合成胜肽及其用途 |
| CN108524919A (zh) | 2012-05-17 | 2018-09-14 | 延伸生物科学股份有限公司 | 用于改进的药物递送的载体 |
| WO2016065052A1 (en) | 2014-10-22 | 2016-04-28 | Extend Biosciences, Inc. | Insulin vitamin d conjugates |
| US9789197B2 (en) | 2014-10-22 | 2017-10-17 | Extend Biosciences, Inc. | RNAi vitamin D conjugates |
| WO2016065042A1 (en) | 2014-10-22 | 2016-04-28 | Extend Biosciences, Inc. | Therapeutic vitamin d conjugates |
| US9526768B2 (en) | 2014-11-13 | 2016-12-27 | Jennifer Mai | Compositions for the treatment of cancer |
| CN110431147A (zh) * | 2017-01-20 | 2019-11-08 | 免疫系统调节控股有限公司 | 新化合物(免疫刺激肽-细胞内感染) |
| WO2018134370A1 (en) * | 2017-01-20 | 2018-07-26 | Immune System Regulation Holding Ab | Novel compounds (immunorhelins) |
| CN110381977A (zh) | 2017-01-20 | 2019-10-25 | 免疫系统调节控股有限公司 | 已知化合物的治疗细胞内感染的新用途 |
| WO2018153961A1 (en) | 2017-02-22 | 2018-08-30 | Immune System Regulation Holding Ab | Gonadotropin-releasing hormones for use as adjuvant immunotherapeutics |
| CN107995138B (zh) * | 2017-12-29 | 2020-10-23 | 中国电子科技集团公司第二十研究所 | Sccpm系统的联合迭代载波同步与解调方法 |
| CN111875673B (zh) * | 2020-07-31 | 2022-03-11 | 江苏莱森生物科技研究院有限公司 | 一种具有抗肿瘤活性的多肽及其用途 |
| CN115326937B (zh) * | 2021-05-11 | 2024-06-18 | 山东省食品药品检验研究院 | 一种基因毒杂质捕捉用固相探针及其使用方法与应用 |
| JP2025534350A (ja) | 2022-09-30 | 2025-10-15 | エクステンド バイオサイエンシズ インコーポレーテッド | 長時間作用型副甲状腺ホルモン |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2029018A1 (en) | 1989-11-01 | 1991-05-02 | Robert P. Millar | Analogues of gonadotropin releasing hormone |
| PT769956E (pt) * | 1994-07-22 | 2000-07-31 | Hampton Roads Medical College | Utilizacao de antagonistas de gnrh para a preparacao de medicamentos para o tratamento de condicoes dependentes de gonado-esteroides |
| US6664369B1 (en) * | 1994-08-10 | 2003-12-16 | Creighton University | GnRH analogues with antitumour effects and pharmaceutical compositions thereof |
| CN1179181A (zh) * | 1995-02-10 | 1998-04-15 | 萨斯喀彻温大学 | GnRH－白细胞毒素嵌合体 |
| DE69737635T2 (de) * | 1996-08-30 | 2008-01-03 | Peptech Ltd., North Ryde | Formulierung zur verzögerten Freisetzung von Peptidagonisten und -analoga des GnRH |
| GB2343182A (en) | 1998-10-27 | 2000-05-03 | Ferring Bv | Use of GnRH-II and analogues thereof for the treatment of osteoporosis |
| GB2344287A (en) | 1998-12-03 | 2000-06-07 | Ferring Bv | Controlled release pharmaceutical formulation |
| US6323179B1 (en) | 1999-10-15 | 2001-11-27 | Theresa Siler-Khodr | Chicken GNRH analogs and uses thereof in regulation of fertility and pregnancy |
| US7109171B2 (en) | 2000-02-28 | 2006-09-19 | Praecis Pharmaceuticals Inc. | Methods for treating FSH related conditions with GnRH antagonists |
| US7834141B1 (en) | 2000-03-31 | 2010-11-16 | Theresa Siler-Khodr | Non-mammalian GnRH analogs and uses thereof in tumor cell growth regulation and cancer therapy |
| US20040152639A1 (en) | 2001-08-28 | 2004-08-05 | Siler-Khodr Theresa M. | Non-mammalian GnRH analogs and uses thereof in regulation of fertility and pregnancy |
| WO2003093304A1 (en) | 2002-05-03 | 2003-11-13 | Neurogenex Co., Ltd. | Agonists and antagonists of gonadotropin-releasing hormone-2, and use thereof |
| GB2397649B (en) * | 2002-07-22 | 2005-12-21 | Ardana Bioscience Ltd | Screening method and anti-tumor drug candidate obtained therefrom |
-
2006
- 2006-08-12 GB GBGB0616111.1A patent/GB0616111D0/en not_active Ceased
-
2007
- 2007-05-01 CN CN201210447203.6A patent/CN102977188B/zh not_active Expired - Fee Related
- 2007-05-01 WO PCT/GB2007/001586 patent/WO2007144554A2/en not_active Ceased
- 2007-05-01 CN CN200780026537.3A patent/CN101553500B/zh not_active Expired - Fee Related
- 2007-05-01 US US12/308,482 patent/US9388216B2/en not_active Expired - Fee Related
- 2007-05-01 JP JP2009514867A patent/JP5290163B2/ja not_active Expired - Fee Related
- 2007-05-01 EP EP07732620.5A patent/EP2029618B1/en not_active Not-in-force
-
2012
- 2012-10-01 JP JP2012219710A patent/JP2013056883A/ja active Pending
Non-Patent Citations (1)
| Title |
|---|
| Chimaeric gonadotropin-releasing hormone (GnRH) peptides with improved affinity for the catfish (Clarias gariepinus) GnRH receptor;Marion BLOMENROHR et al.;《Biochem. J.》;20020201;第361卷(第Pt3期);全文 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013056883A (ja) | 2013-03-28 |
| US9388216B2 (en) | 2016-07-12 |
| CN102977188A (zh) | 2013-03-20 |
| EP2029618B1 (en) | 2015-08-12 |
| JP2009539952A (ja) | 2009-11-19 |
| EP2029618A2 (en) | 2009-03-04 |
| JP5290163B2 (ja) | 2013-09-18 |
| GB0616111D0 (en) | 2006-09-20 |
| WO2007144554A3 (en) | 2008-02-14 |
| US20100234303A1 (en) | 2010-09-16 |
| CN101553500B (zh) | 2014-01-01 |
| CN101553500A (zh) | 2009-10-07 |
| WO2007144554A2 (en) | 2007-12-21 |
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