CN102961719B - Medicament for treating intravertebral postanesthesia shivering - Google Patents
Medicament for treating intravertebral postanesthesia shivering Download PDFInfo
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- CN102961719B CN102961719B CN2012105348110A CN201210534811A CN102961719B CN 102961719 B CN102961719 B CN 102961719B CN 2012105348110 A CN2012105348110 A CN 2012105348110A CN 201210534811 A CN201210534811 A CN 201210534811A CN 102961719 B CN102961719 B CN 102961719B
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Abstract
The invention relates to a medicament for treating intravertebral postanesthesia shivering. The medicament comprises the following materials in parts by weight: 10-20 parts of herba dracocephali integrifolii, 10-25 parts of the root of Chinese pulsatilla, 1-15 parts of soldago decurrens lour, 1-10 parts of snake gourd peel, 1-15 parts of saposhnicovia divaricata, 1-10 parts of trichomanes japonicum thunb., 1-10 parts of dried ginger, 1-15 parts of herba rabdosiae, 1-10 parts of fructus kochiae, 10-20 parts of cistanche salsa, 10-30 parts of semen cassiae, 1-20 parts of crotalaria sessiliflora, 1-10 parts of polygala root, 1-10 parts of aloes and 1-10 parts of paeonia suffruticosa. The medicament for treating intravertebral postanesthesia shivering has the characteristics of being low in cost, easy to prepare, small in toxic and side effects, and obvious in curative effect.
Description
Technical field
The present invention relates to the Anesthesia Department field, specifically, relate to a kind of medicament of shivering with cold after intravertebral anesthesia for the treatment of.
Background technology
After epidural anesthesia, shiver with cold occurring is common complication in the clinical anesthesia process, and its incidence rate can reach 20%-50%.Violent shiver with cold can make the patient extremely uncomfortable, not only affects operation technique and clinical monitoring, and the body oxygen consumption greatly increases, and causes hypoxemia and lactic acidosis, is necessary to be prevented.Therefore, in the urgent need to finding a kind of medicament of shivering with cold after intravertebral anesthesia for the treatment of.
Summary of the invention
The purpose of this invention is to provide a kind of medicament of shivering with cold after intravertebral anesthesia for the treatment of.
In order to realize purpose of the present invention, the invention provides a kind of medicament of shivering with cold after intravertebral anesthesia for the treatment of, it is to be made by the material of following weight proportioning: Herba Dracocephali Integrifolii 10-20 part, Radix Pulsatillae 10-25 part, Herba Solidaginis 1-15 part, Pericarpium Trichosanthis 1-10 part, Radix Saposhnikoviae 1-15 part, Herba Pteridis creticae 1-10 part, Rhizoma Zingiberis 1-10 part, Rabdosia rubescens 1-15 part, Fructus Kochiae 1-10 part, Herba Cistanches 10-20 part, Semen Cassiae 10-30 part, Herba Crotalariae sessiliflorae 1-20 part, Radix Polygalae 1-10 part, Aloe 10-20 part and Cortex Moutan 1-10 part.
The medicament of preferably, shivering with cold after treatment intravertebral anesthesia of the present invention is to be made by the material of following weight proportioning: 5 parts of 15 parts of Herba Dracocephali Integrifoliis, 15 parts of the Radix Pulsatillaes, 5 parts of Herba Solidaginiss, 5 parts of Pericarpium Trichosanthiss, 10 parts of Radix Saposhnikoviaes, 5 parts of Herba Pteridis creticae, 5 parts of Rhizoma Zingiberiss, 10 parts of Rabdosia rubescens, 5 parts of the Fructus Kochiae, 15 parts of Herba Cistanches, 20 parts of Semen Cassiaes, 10 parts of Herba Crotalariae sessiliflorae, 5 parts of Radix Polygalaes, 15 parts of Aloes and Cortex Moutans.
Preferably, medicament of the present invention is tablet, buccal tablet, instant or decoction.
The medicament of shivering with cold after treatment intravertebral anesthesia of the present invention has that cost is low, preparation easily, toxic and side effects characteristics little, evident in efficacy.
The specific embodiment
Embodiment 1: the preparation of decoction of the present invention
Claim Herba Dracocephali Integrifolii 15 grams, the Radix Pulsatillae 15 grams, Herba Solidaginis 5 grams, Pericarpium Trichosanthis 5 grams, Radix Saposhnikoviae 10 grams, Herba Pteridis creticae 5 grams, Rhizoma Zingiberis 5 grams, Rabdosia rubescens 10 grams, the Fructus Kochiae 5 grams, Herba Cistanches 15 grams, Semen Cassiae 20 grams, Herba Crotalariae sessiliflorae 10 grams, Radix Polygalae 5 grams, Aloe 15 grams and Cortex Moutan 5 grams, add 2000 milliliters, water, be placed in the flask of sealing, under the water-bath of 70 ℃, heating is 6 hours, filter, collect filtrate and get final product.
Experimental example
50 routine epidural anesthesia shiver with cold persons are all lower limb, lower abdomen, spinal operation, ASAI-II level, male 30 examples wherein, female's 20 examples, 36 ± 11 years old age, body weight 60 ± 5kg.Preoperative all not medications, the operating room temperature is controlled at 22 ℃-25 ℃, and in art, transfusion is the liquid in room temperature environment.Get T
11-L
4, head-end is put 3 centimetres of pipes, and test dose injects 5 milliliters of 2 volume % lignocaine.Without uncomfortable, append 2 volume % lignocaine 7-15ml after 5 minutes, level of anesthesia reaches requirements of operation.Conventional oxygen supply after anesthesia, monitor HR, NBP, ECG, SPO in art
2.Patient's readme is afraid of cold and is had face and limb muscle independently not to tremble for the shiver with cold case.50 example shiver with cold cases are divided into treatment group and matched group, and every group is 25 examples, and two groups of patients' age, body weight, local anaesthetics consumption, operating time there are no significant difference (P>0.05), have comparability.
50 milliliters of the decoctions of oral embodiment 1 preparation in latter 2 minutes appear in treatment group in shiver with cold, each 4 hours once oral, continuous oral 3 times.Matched group 5 milliliters of latter 2 minutes angular vein injecting normal salines occur in shiver with cold.Observe two groups of patients' shiver with cold situation after 12 hours.
Criterion of therapeutical effect
Produce effects: patient's fear of cold and shiver with cold disappear; Take a turn for the better: fear of cold is arranged but without shiver with cold; Invalid: as to still have fear of cold and shiver with cold.Produce effects+improvement person is considered as effectively.
Therapeutic outcome
Treatment group produce effects 17 examples, 6 examples that take a turn for the better, effective percentage is 92.0%, apparently higher than matched group, difference has significance (P<0.01), in Table 1.
Table 1 liang group curative effect is (example) relatively
Safety analysis
Do not occur serious adverse reaction in observation, after treatment finishes, treatment group patient's blood, urine, stool routine and hepatic and renal function inspection are showed no extremely.
Claims (2)
1. treat the medicament of shivering with cold after intravertebral anesthesia for one kind, it is characterized in that it is to be made by the material of following weight proportioning: Herba Dracocephali Integrifolii 10-20 part, Radix Pulsatillae 10-25 part, Herba Solidaginis 1-15 part, Pericarpium Trichosanthis 1-10 part, Radix Saposhnikoviae 1-15 part, Herba Pteridis creticae 1-10 part, Rhizoma Zingiberis 1-10 part, Rabdosia rubescens 1-15 part, Fructus Kochiae 1-10 part, Herba Cistanches 10-20 part, Semen Cassiae 10-30 part, Herba Crotalariae sessiliflorae 1-20 part, Radix Polygalae 1-10 part, Aloe 10-20 part and Cortex Moutan 1-10 part.
2. the medicament of shivering with cold after treatment intravertebral anesthesia according to claim 1 is characterized in that it is to be made by the material of following weight proportioning: 5 parts of 15 parts of Herba Dracocephali Integrifoliis, 15 parts of the Radix Pulsatillaes, 5 parts of Herba Solidaginiss, 5 parts of Pericarpium Trichosanthiss, 10 parts of Radix Saposhnikoviaes, 5 parts of Herba Pteridis creticae, 5 parts of Rhizoma Zingiberiss, 10 parts of Rabdosia rubescens, 5 parts of the Fructus Kochiae, 15 parts of Herba Cistanches, 20 parts of Semen Cassiaes, 10 parts of Herba Crotalariae sessiliflorae, 5 parts of Radix Polygalaes, 15 parts of Aloes and Cortex Moutans.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105348110A CN102961719B (en) | 2012-12-06 | 2012-12-06 | Medicament for treating intravertebral postanesthesia shivering |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012105348110A CN102961719B (en) | 2012-12-06 | 2012-12-06 | Medicament for treating intravertebral postanesthesia shivering |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102961719A CN102961719A (en) | 2013-03-13 |
| CN102961719B true CN102961719B (en) | 2013-12-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2012105348110A Expired - Fee Related CN102961719B (en) | 2012-12-06 | 2012-12-06 | Medicament for treating intravertebral postanesthesia shivering |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106039000A (en) * | 2014-04-28 | 2016-10-26 | 李学新 | Preparation method of medicine capable of lowering morbidity of PS (postanesthesia shivering) |
| CN104998242A (en) * | 2015-08-18 | 2015-10-28 | 密夫丽 | Medicine for preventing and treating post intraspinal anesthesia shivering and preparation method of medicine |
| CN104998246A (en) * | 2015-08-28 | 2015-10-28 | 济南舜昊生物科技有限公司 | Drug for preventing and curing shiver after intraspinal anesthesia and preparation method thereof |
| CN105168768A (en) * | 2015-09-01 | 2015-12-23 | 卜祥梅 | Medicine composition for treating postanesthesia shivering |
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2012
- 2012-12-06 CN CN2012105348110A patent/CN102961719B/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
|---|
| "参附注射液防治围麻醉期剖宫产产妇寒战的临床观察";白延仓;《四川中医》;20031231;第21卷(第5期);55 * |
| 白延仓."参附注射液防治围麻醉期剖宫产产妇寒战的临床观察".《四川中医》.2003,第21卷(第5期),55. |
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| CN102961719A (en) | 2013-03-13 |
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