Background technology
Coronary heart disease is the abbreviation of coronary heart disease, refer to because lipid metabolism is undesired, lipid calmness in the blood is on the endarterium of otherwise smooth, lipid material accumulation at some similar medicated porridge samples of endarterium forms white speckle, these specklees gradually increase and cause lumen of artery narrow, blood flow is obstructed, causes heart ischemia, produce angina pectoris.Coronary heart disease is the major disease of serious threat health and lives, and its sickness rate, mortality rate are improving year by year, b referred to as " the first human killer ".At present, modern medicine has been obtained obvious progress at Drug therapy, operative treatment and the interventional therapy of coronary heart disease.Mainly be to adopt nitrate esters, statins antilipemic medicine, anti-platelet agent, beta-blocker and calcium channel blocker in Drug therapy.Its treatment approach improves myocardial oxygen delivery and reduces myocardial oxygen consumption, thereby alleviate state of an illness symptom mainly with the medicine that adopts coronary dilating and decreased heart rate.Facts have proved, though this class medicine can be alleviated disease to a certain extent, after the drug withdrawal easily repeatedly.
Coronary heart disease, the traditional Chinese medical science claim " thoracic obstruction ".The traditional Chinese medical science thinks, since worn with age, healthy energy virtual loss, function damage, yin and yang qi and blood disorder adds the impact of the factors such as internal injury caused by excess of seven emotions, eating and drinking without temperance, cold stimulation, work and rest mistake degree, causes qi depression to blood stasis, hypofunction of YANG QI in chest, the turbid interior life of expectorant makes blockage of the cardiac vessels and causes a disease.Wherein, internal organs meridian qi and blood functional disorder, the balance of human body YIN and YANG in a relative equilibrium is destroyed, is the immanent cause of morbidity.Though the sick position of this disease is in mind, its whole pathological process invariably with all dirty close ties that have of liver,spleen,kidney.
According to theory of Chinese medical science, for the pathogeny of coronary heart disease, promote blood circulation as the Therapeutic Principle take intestinal stasis relieving, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Can only alleviate after disease, the drug withdrawal easily repeatedly deficiency in order to overcome prior art western medicines in treatment coronary heart disease, the invention provides a kind ofly prepare conveniently, the medicine source is wide, cost is low, the Chinese medicine composition of evident in efficacy, reliable effect, the treatment coronary heart disease that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of coronary heart disease is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: 5~20 parts of Radix Bupleuri, 10~30 parts of the Radix Paeoniae Albas, 5~20 parts of Fructus Trichosanthis, 5~20 parts of Bulbus Allii Macrostemonis, 10~30 parts of Radix Salviae Miltiorrhizaes, 5~20 parts in Semen Persicae, 5~20 parts on Flos Carthami, 10~30 parts of Rhizoma Chuanxiongs, 5~25 parts of Radix Angelicae Sinensis, 10~30 parts of Semen Cassiaes, 5~20 parts of Ramulus Uncariae Cum Uncis, 5~25 parts of Semen Platycladi, 10~30 parts of Concha Ostreaes.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of coronary heart disease is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: 12 parts of Radix Bupleuri, 20 parts of the Radix Paeoniae Albas, 12 parts of Fructus Trichosanthis, 10 parts of Bulbus Allii Macrostemonis, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts in Semen Persicae, 10 parts on Flos Carthami, 20 parts of Rhizoma Chuanxiongs, 15 parts of Radix Angelicae Sinensis, 20 parts of Semen Cassiaes, 12 parts of Ramulus Uncariae Cum Uncis, 15 parts of Semen Platycladi, 20 parts of Concha Ostreaes.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In the Chinese medicine composition of the present invention: Radix Bupleuri have evacuate bring down a fever, the effect of yang invigorating soothing liver-QI; The Radix Paeoniae Alba has the effect of clear and coherent blood vessels, nourishing blood to suppress the hyperactive liver, slow middle arresting sweating; Fructus Trichosanthis has clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes the effect of laxation; Bulbus Allii Macrostemonis has the effect of activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving, the chest stuffiness relieving of regulating the flow of vital energy; Radix Salviae Miltiorrhizae has the effect of promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Semen Persicae has the effect of blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation; Flos Carthami has the effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Rhizoma Chuanxiong has the effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, the effect of menstruction regulating and pain relieving, loosening bowel to relieve constipation; Semen Cassiae has the effect of clearing away heat to improve acuity of vision, loosening bowel to relieve constipation; Ramulus Uncariae Cum Uncis has the effect of heat clearing away suppressing the hyperactive liver, relieving spasm by subduing liver-wind; Semen Platycladi has the effect of tranquilizing by nourishing the heart, nourishing YIN and benefiting blood; The effect of Concha Ostreae convergence calmness, YANG hyperactivity suppressing arresting seminal emission, resolving phlegm and softening hard masses.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, plays altogether the effect of yang invigorating soothing liver-QI, relieving stuffiness of the chest by dispersing aggregation of pathogens, circulation of qi promoting intestinal stasis relieving, blood circulation promoting and blood stasis dispelling, clear and coherent blood vessels, reaches the purpose for the treatment of coronary heart disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, the medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the usefulness that is decocted in water for oral dose.Through the clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, toxic and side effects do not occur, total effective rate 95%, cure rate reaches 50%.
The specific embodiment
The present invention will be further described below in conjunction with embodiment.
Embodiment 1
A kind of Chinese medicine composition for the treatment of coronary heart disease, its raw material of Chinese medicine by following weight proportion forms: Radix Bupleuri 12g, Radix Paeoniae Alba 20g, Fructus Trichosanthis 12g, Bulbus Allii Macrostemonis 10g, Radix Salviae Miltiorrhizae 20g, Semen Persicae 10g, Flos Carthami 10g, Rhizoma Chuanxiong 20g, Radix Angelicae Sinensis 15g, Semen Cassiae 20g, Ramulus Uncariae Cum Uncis 12g, Semen Platycladi 15g, Concha Ostreae 20g.
Embodiment 2
A kind of Chinese medicine composition for the treatment of coronary heart disease, its raw material of Chinese medicine by following weight proportion forms: Radix Bupleuri 20g, Radix Paeoniae Alba 15g, Fructus Trichosanthis 5g, Bulbus Allii Macrostemonis 15g, Radix Salviae Miltiorrhizae 10g, Semen Persicae 20g, Flos Carthami 5g, Rhizoma Chuanxiong 30g, Radix Angelicae Sinensis 10g, Semen Cassiae 15g, Ramulus Uncariae Cum Uncis 20g, Semen Platycladi 5g, Concha Ostreae 15g.
Embodiment 3
A kind of Chinese medicine composition for the treatment of coronary heart disease, its raw material of Chinese medicine by following weight proportion forms: Radix Bupleuri 5g, Radix Paeoniae Alba 25g, Fructus Trichosanthis 10g, Bulbus Allii Macrostemonis 20g, Radix Salviae Miltiorrhizae 15g, Semen Persicae 5g, Flos Carthami 20g, Rhizoma Chuanxiong 10g, Radix Angelicae Sinensis 20g, Semen Cassiae 25g, Ramulus Uncariae Cum Uncis 5g, Semen Platycladi 10g, Concha Ostreae 30g.
Embodiment 4
A kind of Chinese medicine composition for the treatment of coronary heart disease, its raw material of Chinese medicine by following weight proportion forms: Radix Bupleuri 15g, Radix Paeoniae Alba 10g, Fructus Trichosanthis 20g, Bulbus Allii Macrostemonis 5g, Radix Salviae Miltiorrhizae 30g, Semen Persicae 12g, Flos Carthami 15g, Rhizoma Chuanxiong 25g, Radix Angelicae Sinensis 5g, Semen Cassiae 30g, Ramulus Uncariae Cum Uncis 15g, Semen Platycladi 25g, Concha Ostreae 12g.
Embodiment 5
A kind of Chinese medicine composition for the treatment of coronary heart disease, its raw material of Chinese medicine by following weight proportion forms: Radix Bupleuri 10g, Radix Paeoniae Alba 30g, Fructus Trichosanthis 15g, Bulbus Allii Macrostemonis 12g, Radix Salviae Miltiorrhizae 25g, Semen Persicae 20g, Flos Carthami 12g, Rhizoma Chuanxiong 15g, Radix Angelicae Sinensis 25g, Semen Cassiae 10g, Ramulus Uncariae Cum Uncis 10g, Semen Platycladi 20g, Concha Ostreae 10g.
Chinese medicine composition in embodiment of the invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soaked 15~20 minutes, add water again and do not have about 8 centimetres of powder, carry out decocting the first time, at a simmer the front intense fire that adopts decocts, and it is rear with slow fire boiling 20~30 minutes to boil; When decocting for the second time, add water and do not have about 6 centimetres of powder, the water rear decoction 15~20 minutes of boiling.Twice decoction extracting juice that removes slag merges.
A kind of Chinese medicine composition for the treatment of coronary heart disease, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to observe 80 cases, male 45 examples wherein, women 35 examples; 40~80 years old age, average 51 ± 9 years old.
Two, diagnosis basis:
(1), feel oppressed pain, the very then positions such as the thorough left shoulder back of the body of pain, throat, left upper arm inboard of Danzhong or pareordia.Being ictal or lasting does not understand.Often with shortness of breath and palpitation, spontaneous perspiration, very then failing to sleep due to dyspnea;
(2), general several seconds of feeling of oppression and pain in the chest is alleviated to dozens of minutes.But the severe patient sharp ache continue not to be understood, cold extremities due to sweating, and pale complexion, cyanosis of the lips and nails, palpitating speed, or the crisis such as arrhythmia can be died suddenly;
(3), be more common in above middle age, often because overworking, depressed angry or polydipsia gluttony, impression is cold and bring out;
(4), look into electrocardiogram, ambulatory electrocardiogram, exercise test etc. to clarify a diagnosis.Make in case of necessity Myocardiase Examination, Dynamic Observation of Electrocardiograms.
Three, usage and dosage: during clinical practice, the component in the compositions, consumption are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.Fortnight is a course for the treatment of, one day potion, the about 300ml of twice extracting juice of decocting, minute morning, late twice warm taking.
Four, efficacy evaluation:
(1), cure: transference cure, electrocardiogram and relevant lab testing recover normal;
(2), take a turn for the better: sx↓, attack times reduces, the intermission prolongs, lab testing is improved;
(3), do not heal: cardinal symptom and electrocardiogram are without change.
Five, therapeutic effect: in this clinical observation case, take medicine 1~6 course for the treatment of, cure 40 examples, 36 examples that take a turn for the better, invalid 4 examples.Toxic and side effects does not occur during the treatment.
Six, model case:
Case 1:
Poplar, man, 55 years old.Suffer from hypertension for many years, frequent twinge uncomfortable in chest, nervous, breathe hard dizziness, headache dim eyesight.Recently nervous suddenly, breathe hard and increase the weight of, walk slowly, sweating while acting, the rest of can not squaring one's shoulders, be badly in need of squatting down, two edema of lower limbs, general weakness, poor appetite, Electrocardioscopy is myocardial ischemia, Hyperlipidemia (triglyceride 6.34mm0l/l), blood glucose are slightly high.Take 1 course for the treatment of of medicament that Chinese medicine composition of the present invention prepares, the electrocardio diagram: sinus rhythm, idol have early rich, and spirit is front strong; Continuous take 1 course for the treatment of, the rich disappearance early, above-mentioned symptom obviously alleviates, and continues to strengthen to take 2 courses for the treatment of, and blood pressure, blood fat all recover normally, and spirit is strong, healing.
Case 2:
To certain, man, 62 years old.Recent twinge uncomfortable in chest connects and the shoulder back of the body, and is nervous, breathe hard, hyperhidrosis, insomnia, with dizzy, body be stranded unable, Yao Xi Acid is soft, shakiness of walking, xerostomia, the scarce Tianjin of red tongue white and thin fur, the thin string of pulse condition is unable.Take 1 course for the treatment of of medicament of Chinese medicine composition preparation of the present invention, uncomfortable in chest sharp, palpitation and short breath, the hyperhidrosis insomnia is clearly better; Continuous take 2 courses for the treatment of, blood pressure is normal, spirit is strong before; Continue to strengthen and take 1 course for the treatment of, above-mentioned all diseases disappear, and recover normal.