CN102949252A - Test device for in vitro release and performance simulation of intervening valves - Google Patents
Test device for in vitro release and performance simulation of intervening valves Download PDFInfo
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- CN102949252A CN102949252A CN2012104228658A CN201210422865A CN102949252A CN 102949252 A CN102949252 A CN 102949252A CN 2012104228658 A CN2012104228658 A CN 2012104228658A CN 201210422865 A CN201210422865 A CN 201210422865A CN 102949252 A CN102949252 A CN 102949252A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2472—Devices for testing
Abstract
The invention relates to a test device for in vitro release and performance simulation of intervening valves. The test device comprises a software control device, a pulse driving device and an in vitro simulation device, wherein the software control device comprises a circuit integration module and operation software, the software control device is provided with a signal adjusting output channel and a data collection input channel, the pulse driving device is a power driving mechanism, in the in vitro simulation device, a simulation ventricle of a simulation body is connected with an artificial aortic blood vessel of the simulation body, and then is connected with an artificial aortic arch blood vessel which extends from aorta arch to femoral artery in the proportion of the body, the in vitro simulation device is provided with a temperature adjusting feedback system, a camera system and a damping system, the temperature adjusting feedback system is used for adjusting the temperature of fluid circulating in the test device, the camera system is used for observing or shooting in the intervening valve release and detection, and the damping system is used for simulating the drag and compliance of a cardiovascular system of the simulation body. The test device has the advantages that an operator can more conveniently and visually acknowledge the operation process of the intervening valves, and the proficiency degree and success rate of the operation are improved.
Description
Technical field
The present invention relates to medical instruments field.
Background technology
Along with the development of social senilization, the heart disease sickness rate constantly increases, and valvular heart disease is one of at present main heart disease.Wherein aortic stenosis is modal a kind of disease in the valvular heart disease.Its unique therapeutic modality of most of aortic stenosis in patients is carried out artificial valve replacement exactly.Cardiac valve prosthesis is divided into two kinds of mechanical valve prosthesis and biovalves.Along with artificial valve's generation, need corresponding testing tool to test artificial valvular properties.But present most checkout gear valve place and the simulation of aorta line size aspect etc. test result is had certain impact.
Development along with Wicresoft's interventional technique, to injury of human still less the intervention aortic valve and get involved cusps of pulmonary valve and be developed out, not only can reduce greatly patient's damage but also be a kind of effective treatment means for the patient that a part is not suitable for out the breast valve replacement.But present artificial valve's checkout gear is only applicable to out the detection of breast valve, for getting involved valve and inapplicable.The test that gets involved valve need to be simulated body operation and is discharged into its relevant performance of test after the lesion locations, except opening the index of correlation that the breast valve need to test, also has some special indexs to need test.Such as the valve release performance, whether displacement arranged, whether whether influential etc. to coronary artery Bicuspid valve had compressing.The device of test valve performance does not all satisfy the test request of getting involved valve at present.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of can be used for the getting involved in-vitro simulated release of valve and performance test device, thereby made the driver output of the easypro contracting of pulse driving device generation simulation healthy human body heart make in-vitro simulated device can simulate the Circuluting puls state of healthy human body by the parameter setting of software controlled machine.Use induction system to get involved by femoral artery or the mode of apex of the heart puncture will get involved valve be transported to the release of aortic stenosis position not only can detect the traditional performance parameter of valve and also can observe valve release performance, whether be shifted, whether influential to coronary artery, whether Bicuspid valve is had other performance parameters such as compressing.The convenient operation process of getting involved valve that gets information about of operator be can also make by this covering device, operation proficiency and success rate improved.
For reaching above-mentioned purpose, a kind of can be used for the getting involved in-vitro simulated release of valve and performance test device provided by the invention comprise software controlled machine, pulse driving device and in-vitro simulated device; Described software controlled machine comprises circuit integrated module and function software, have conditioning signal output channel and data acquisition input channel, described pulse driving device is power-driven mechanism, described in-vitro simulated device comprises the artificial aorta vessel of the simulation ventricle connecting analog human body of simulating human body, then connect press human body proportion from the arcus aortae,artificial blood vessel of aortic arch up to femoral artery; Described in-vitro simulated device has homoiothermic feedback system for the temperature of liquid of regulating described test set internal recycle, be used for discharging and detecting the camera system of observing or taking pictures and be used for the resistance of simulation cardiovascular system of human body and the damping system of compliance getting involved valve.
Simulate ventricle, artificial aorta vessel, made by transparent silica gel from aortic arch.
Described software controlled machine can carry out parameter setting, unit state record and sensing data is processed test set.
Described pulse driving device can be converted into input signal the power output of simulation healthy human body heartbeat.
Described simulation ventricle has a puncture orifice, a connector and the inlet that is connected input duct that connects artificial aorta vessel.
Inlet has a Bicuspid valve of making of the transparent silica gel simulation in the position that itself and the connector that is connected artificial aorta vessel face mutually as mentioned above.
Described artificial aorta vessel has three aortic sinus, lower stenosed valve of facing the silica gel simulation, and have left and right two coronary ostiums.
Left and right two coronary ostiums are placed with sensor as mentioned above.
Described artificial aorta vessel is placed with sensor at near-end and far-end.
Described arcus aortae,artificial's blood vessel has one and gets involved mouth.
Described in-vitro simulated device has homoiothermic feedback system, camera system and damping system.
By such scheme as seen, the invention has the advantages that, described can be used for getting involved the in-vitro simulated release of valve and performance test device can simulate the dispose procedure of body operation not only can detect the traditional performance parameter of valve and also can observe valve release performance, whether be shifted, whether influential to coronary artery, whether Bicuspid valve is had other performance parameters such as compressing.
Description of drawings
Fig. 1 is operation principle sketch map of the present invention.
Fig. 2 is simplified structure diagram of the present invention.
1. simulate ventricle 2. artificial aorta vessel 3. arcus aortae,artificial's blood vessels
4. Bicuspid valve 5. puncture orifice 6. get involved mouthful 7. aortic valve lower sensors
8. coronary ostium sensor 9. aortic valve upper sensors 10. homoiothermic feedback systems
11. the first damping system 112. second damping systems 213. calcification valves 14. input duct
15. camera system 16. connectors 117. connectors 218 inlets
50. pressure transducer 80. main parts 60. damping systems
100. software controlled machine, 200. pulse driving devices, 300. in-vitro simulated devices
The specific embodiment
Figure 1 shows that to can be used for getting involved the in-vitro simulated release of valve and performance test device fundamental diagram, functions is described below:
Software controlled machine 100 comprises circuit integrated module and function software, has conditioning signal output channel and data acquisition input channel.The conditioning signal output channel can send the driving signal that simulation healthy human body heart relaxes and contracts to pulse driving device 200, data acquisition channel not only can be by fluid pressure and flow in the in-vitro simulated device 300 of sensor periodic measurement variation and also test set state parameter and associated fluid data can be recorded and process to detect the correlated performance of valve, average pressure gradient for example, average discharge, stroke volume, cycling rate, the mean aortic pressure of a complete cycle, the duration in forward-flow stage, regurgitation volume under 3 cycling rates, on impact coronarius etc.
Pulse driving device: be power-driven mechanism.Can produce the stroke volume of 30mL-150mL and the cycling rate of 40 circulation/min-120 circulation/min by in-vitro simulated device.
In-vitro simulated device: with healthy human body Circuluting puls equivalent model, can simulate the resistance of whole body vascular system and the compliance of whole body vascular system.And can be according to size and the cardiac output of valve, be that 14.3kPa-19.5kPa (110mmHg-150mmHg) and aortic diastolic pressure are to simulate 13kPa ± 0.65kPa (mean aortic pressure of 100mmHg ± 5mmHg) under the condition of 7.8kPa-11.7kPa (60mmHg-90mmHg) at the aorta peak systolic pressure.When cycling rate is 70 circulation/min ± 10 circulation/min, put out the forward-flow stage to account for 35% ± 5% of whole circulation time.The temperature that can keep circulating fluid in whole checkout gear running is 35 ℃-40 ℃.
Shown in Figure 2ly can be used for getting involved the in-vitro simulated release of valve and the performance test device comprises software controlled machine 100, pulse driving device 200 and in-vitro simulated device 300.The main part 80 of in-vitro simulated device 300 is to use transparent silica gel simulation healthy human body ventricle and vascular system to make, and simulation ventricle 1 connects artificial aorta vessel 2 and then connects arcus aortae,artificial's blood vessel 3 by connector 217 by connector 116.
There is one on the simulation ventricle 1 for the puncture orifice 5 of apex of the heart puncture operation and belt switch, its inlet 18 is having a Bicuspid valve 4 of making of the transparent silica gel simulation with position that the connector 116 that is connected artificial aorta vessel 2 faces mutually, is used for preventing whether backflowing of liquid also has compressing for detection of getting involved valve to Bicuspid valve 4 simultaneously when simulating ventricle 1 shrinks.What link to each other with inlet 18 is input duct 14, at the lower position that connects artificial aorta vessel 2 an aortic valve lower sensor 7 that is used for the valve conventional sense is arranged.The outside of whole simulation ventricle is wrapped up by the first damping system 11, and is connected with pulse driving device by the first damping system 11, thereby realizes the easypro contracting activity of simulation ventricle 1.
Upside at artificial aorta vessel 2 has an aortic valve upper sensor 9 to be used for the detection of valve traditional performance.Whether there are two coronary ostium sensors 8 position similar to the Human Physiology coronary artery on artificial aorta vessel 2, influential to coronary artery for detection of the valve after discharging.If the valve of getting involved is influential to coronary artery, the numerical value of the numerical value of aorta upper sensor 9 and coronary ostium sensor 8 just has larger discrepancy.If without impact, then the numerical value of aorta upper sensor 9 will be similar to identical with the numerical value of coronary ostium sensor 8 valve of getting involved on coronary artery.In the position similar to the Human Physiology aortic valve a fully calcification valve 13 of closure that uses silica gel to make is arranged on the artificial aorta vessel 2, in order to simulate narrow aortic valve.Artificial aorta vessel 2 is regulated its relevant parameter by the second damping system 12 that its outside coats, with simulation human blood circulatory system's resistance and compliance.
The head end of arcus aortae,artificial's blood vessel 3 has a part straight section to be used for placing camera system 15, can in the whole process that gets involved valve release and detect valve be observed and take pictures.Afterbody has the intervention mouth 6 of a right issue arterial intervention operation use and belt switch, so that carry the intervention valve by femoral artery puncture.
In-vitro simulated device remains between 35 ℃-40 ℃ by the temperature of liquid of homoiothermic feedback system 10 assurance devices circulation.
Apex of the heart puncture mode is after test set operation, uses intervention valve that induction system will load to be transported to the position of the calcification valve 13 in the artificial aorta vessel 2 by the puncture orifice 5 of simulating ventricle 1, then will get involved valve by induction system and discharge.
The femoral artery intervening mode is after the test set operation, use intervention valve that induction system will load to be transported to the position of the calcification valve 13 in the artificial aorta vessel 2 by the intervention mouth 6 of artificial blood vessel 3, then will get involved valve by induction system and discharge.
In getting involved the process that valve discharges, can observe by transparent silica gel get involved position that valve discharges whether correctly, whether oppress Bicuspid valve 4, whether the performance parameter such as displacement arranged after releasing.Not only can detect the traditional performance parameter that gets involved valve but also can detect whether get involved valve influential to coronary artery by test set, and can observe the open and-shut mode of getting involved valves by camera system 15.
The convenient operation process of getting involved valve that gets information about of operator be can also make by this covering device, operation proficiency and success rate improved.
Claims (10)
1. one kind can be used for getting involved the in-vitro simulated release of valve and performance test device, comprises software controlled machine, pulse driving device and in-vitro simulated device; It is characterized in that, described software controlled machine comprises circuit integrated module and function software, have conditioning signal output channel and data acquisition input channel, described pulse driving device is power-driven mechanism, described in-vitro simulated device comprises the artificial aorta vessel of the simulation ventricle connecting analog human body of simulating human body, then connect press human body proportion from the arcus aortae,artificial blood vessel of aortic arch up to femoral artery; Described in-vitro simulated device has homoiothermic feedback system for the temperature of liquid of regulating described test set internal recycle, be used for discharging and detecting the camera system of observing or taking pictures and be used for the resistance of simulation cardiovascular system of human body and the damping system of compliance getting involved valve.
2. test set as claimed in claim 1 is characterized in that, described software controlled machine carries out parameter setting, unit state record and date processing to described test set.
3. test set as claimed in claim 1 is characterized in that, described pulse driving device is converted into the power output that the simulation human heart is beaten with input signal.
4. test set as claimed in claim 1 is characterized in that, described simulation ventricle has a puncture orifice, a connector and the inlet that is connected input duct that connects artificial aorta vessel.
5. test set as claimed in claim 4 is characterized in that, described inlet has a Bicuspid valve of making of the transparent silica gel simulation in the position that itself and the connector that is connected artificial aorta vessel face mutually.
6. test set as claimed in claim 1 is characterized in that, described artificial aorta vessel has three aortic sinus, has the calcification valve of silica gel simulation, and has left and right two coronary ostiums.
7. test set as claimed in claim 6 is characterized in that, described artificial aorta vessel is placed with sensor at near-end and far-end.
8. test set as claimed in claim 6 is characterized in that, described left and right two coronary ostiums are placed with sensor.
9. test set as claimed in claim 1 is characterized in that, described arcus aortae,artificial's blood vessel has one to be got involved mouth and is connected a connector that connects artificial aorta vessel.
10. test set as claimed in claim 1 is characterized in that, simulates ventricle, artificial aorta vessel, is made by transparent silica gel from aortic arch.
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| CN201210422865.8A CN102949252B (en) | 2012-10-16 | 2012-10-16 | Can be used for getting involved the in-vitro simulated release of valve and performance testing device |
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| CN107610571A (en) * | 2016-07-11 | 2018-01-19 | 苏州迈迪威检测技术有限公司 | Simulate blood pathway system |
| CN107773328A (en) * | 2016-08-24 | 2018-03-09 | 上海市同济医院 | Testing external performance system and its method of testing through conduit mitral valve support |
| CN109172047A (en) * | 2018-09-18 | 2019-01-11 | 上海工程技术大学 | Heart valve prosthesis function test system |
| CN109841137A (en) * | 2019-02-14 | 2019-06-04 | 上海长海医院 | Root of ascending aorta intracavitary therapy training pattern |
| CN110478083A (en) * | 2019-08-21 | 2019-11-22 | 沛嘉医疗科技(苏州)有限公司 | A kind of valvular vitro test system and its test method |
| CN110974318A (en) * | 2019-11-25 | 2020-04-10 | 西安马克医疗科技有限公司 | External simulation device and simulation system for transcatheter aortic valve replacement |
| CN111640359A (en) * | 2020-06-05 | 2020-09-08 | 遂宁市中心医院 | Coronary operation external training rehabilitation test system |
| CN114299805A (en) * | 2021-12-29 | 2022-04-08 | 赛诺医疗科学技术股份有限公司 | Intracranial intervention simulation device, system and method |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107610571A (en) * | 2016-07-11 | 2018-01-19 | 苏州迈迪威检测技术有限公司 | Simulate blood pathway system |
| CN107773328A (en) * | 2016-08-24 | 2018-03-09 | 上海市同济医院 | Testing external performance system and its method of testing through conduit mitral valve support |
| CN107773328B (en) * | 2016-08-24 | 2023-10-03 | 上海市同济医院 | In-vitro performance test system and method for transcatheter mitral valve stent |
| CN109172047A (en) * | 2018-09-18 | 2019-01-11 | 上海工程技术大学 | Heart valve prosthesis function test system |
| CN109172047B (en) * | 2018-09-18 | 2023-09-15 | 上海工程技术大学 | Prosthetic heart valve function test system |
| CN109841137A (en) * | 2019-02-14 | 2019-06-04 | 上海长海医院 | Root of ascending aorta intracavitary therapy training pattern |
| CN109841137B (en) * | 2019-02-14 | 2023-10-27 | 上海长海医院 | Ascending aorta root intracavity treatment training model |
| CN110478083A (en) * | 2019-08-21 | 2019-11-22 | 沛嘉医疗科技(苏州)有限公司 | A kind of valvular vitro test system and its test method |
| CN110974318A (en) * | 2019-11-25 | 2020-04-10 | 西安马克医疗科技有限公司 | External simulation device and simulation system for transcatheter aortic valve replacement |
| CN111640359A (en) * | 2020-06-05 | 2020-09-08 | 遂宁市中心医院 | Coronary operation external training rehabilitation test system |
| CN114299805A (en) * | 2021-12-29 | 2022-04-08 | 赛诺医疗科学技术股份有限公司 | Intracranial intervention simulation device, system and method |
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Address after: 101312 No.5, Zhuyuan 2nd Street, Shunyi District, Beijing (Tianzhu Comprehensive Bonded Zone) Patentee after: Beijing medipeak Medical Technology Co.,Ltd. Address before: 101312 No.5, Zhuyuan 2nd Street, Shunyi District, Beijing (Tianzhu Comprehensive Bonded Zone) Patentee before: BEIJING MED ZENITH MEDICAL SCIENTIFIC Co.,Ltd. |