CN101658696A - Blood circulation simulating system used for testing blood pump performance - Google Patents
Blood circulation simulating system used for testing blood pump performance Download PDFInfo
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- CN101658696A CN101658696A CN200910153107A CN200910153107A CN101658696A CN 101658696 A CN101658696 A CN 101658696A CN 200910153107 A CN200910153107 A CN 200910153107A CN 200910153107 A CN200910153107 A CN 200910153107A CN 101658696 A CN101658696 A CN 101658696A
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- spring
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- liquid
- blood pump
- blood circulation
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- 239000008280 blood Substances 0.000 title claims abstract description 22
- 210000004369 blood Anatomy 0.000 title claims abstract description 22
- 230000017531 blood circulation Effects 0.000 title claims abstract description 18
- 238000012360 testing method Methods 0.000 title claims abstract description 13
- 239000007788 liquid Substances 0.000 claims abstract description 45
- 239000012530 fluid Substances 0.000 claims description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 3
- 239000000741 silica gel Substances 0.000 claims description 3
- 229910002027 silica gel Inorganic materials 0.000 claims description 3
- 239000012528 membrane Substances 0.000 abstract 4
- 230000035790 physiological processes and functions Effects 0.000 abstract 1
- 210000004204 blood vessel Anatomy 0.000 description 8
- 238000004088 simulation Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 4
- 230000006835 compression Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000002792 vascular Effects 0.000 description 3
- 230000000747 cardiac effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000012827 research and development Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000003205 diastolic effect Effects 0.000 description 1
- 210000002837 heart atrium Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 230000002861 ventricular Effects 0.000 description 1
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Abstract
The invention discloses a blood circulation simulating system used for testing the blood pump performance. A direct current motor is connected with a cam mechanism; a driven element of the cam mechanism is connected with a spiral part of a spiral container filled with liquid; two ends of a non-spiral part of the spiral container are respectively communicated with a first one-way membrane and a second one-way membrane; after the first one-way membrane is communicated with a cylindrical container filled with liquid, the cylindrical container is connected with one end of a spiral pipeline; the second one-way membrane is communicated with the liquid at one end of a frictionless cylinder which is provided with a spring and filled with liquid; the liquid at the other end of the spiral pipeline is communicated with the liquid in the frictionless cylinder which is provided with the spring and filled with liquid through a pneumatic pipe; the spring end at the other end of the frictionless cylinder which is provided with the spring is connected with an adjusting screw; and the cylindrical container and the frictionless cylinder which is provided with the spring are respectively provided witha joint communicated with the blood pump. The blood circulation simulating system used for testing the blood pump performance has the characteristics of simple structure, small volume, easy adjustingof a plurality of physiological parameters, and can realize various main physiological functions of a blood circulation system.
Description
Technical field
The present invention relates to biomedical engineering technology, especially relate to a kind of blood circulation simulating system that is used for testing blood pump performance.
Background technology
Blood pump is as ventricular assist device, for the patient who waits for heart transplantation provides a kind of solution.Blood pump need carry out zoopery and tested its performance parameter in the past, often the time long, expend many.And blood circulation simulating system is developed in order to address this problem, and it can test the performance of blood pump, shortens the cycle of blood pump research and development.
At present, blood circulation simulating system all adopts the elastic cavity principle to come the compliance of simulated blood vessel, and the elastic cavity employing is marked with certain compressed-air actuated container and obtains.For the resistance characteristics of blood vessel, generally all adopt orifice valve to reach (can referring to Chinese patent CN1846605A and CN101380490A).And as for the simulation of cardiac pumping, some blood circulation simulating systems directly use the blood pump of research and development to realize, this method can not observe blood pump not have under the total failure mode influence to blood circulation at human heart; Also adopt compressed air to enter or amount discharge container in addition by electromagnetic valve just like University of Queensland, so that the liquid in the container is discharged or is sucked, the frequency that the control electromagnetic valve opens and closes can obtain corresponding heart rate, this method can be simulated whole blood circulation, but the volume that takies is very big, and expends also very high.Container chamber simulated blood vessel compliance above-mentioned in addition and orifice valve simulated blood vessel resistance also have relatively large volume.
Summary of the invention
The purpose of this invention is to provide a kind of blood circulation simulating system that is used for testing blood pump performance, can realize the simulation of heartbeat and blood vessel physiological feature.
For achieving the above object, the technical solution used in the present invention is as follows:
Nothing friction cylinder, spirality pipe, cam mechanism, two joints of comprising spiral container and cylindrical chamber, two unidirectional diaphragms, pneumatic tube, band spring; The cam rotation of the cam mechanism that is connected with direct current generator, driven member through cam mechanism, change the linear reciprocating motion of driven member into, the spiral part of the spiral container of dress liquid was done stretching motion in the driven member top drove, the two ends of the no spiral part of spiral container are respectively with first, the second unidirectional diaphragm is communicated with, the first unidirectional diaphragm is with after the cylindrical chamber of interior dress liquid is communicated with, the cylindrical chamber of interior dress liquid connects an end of spirality pipe, the nothing friction cylinder one end fluid connection of the band spring of the second unidirectional diaphragm and interior dress liquid, the liquid of the spirality pipe other end is fluid connection in the nothing friction cylinder of the band spring of pneumatic tube and interior dress liquid, the nothing friction cylinder other end spring terminal of the band spring of interior dress liquid is connected with adjustment screw, is respectively equipped with a joint that is communicated with blood pump on the nothing friction cylinder of the band spring of the cylindrical chamber of interior dress liquid and interior dress liquid.
Described spiral container is made by silica gel, is divided into spiral and no spiral two parts, and wherein the pitch P of spiral part is 10～15mm, and 6～8 teeth are arranged; Bottom surface diameter 30～40mm, volume altogether is 100～150mL, wherein compressible part is divided into 70～100mL.
Described unidirectional diaphragm is made of two semicircle valves and chassis, and valve is that axial symmetry is installed on the chassis with the diameter, is connected by fulcrum, and valve connects a spring respectively around 45～60 ° of rotations of fulcrum on each valve; Chassis and pipeline are bonding, and first unidirectional diaphragm-operated band spring one end is towards spiral container, and second unidirectional diaphragm-operated band spring one end is towards the nothing friction cylinder of band spring, and whole unidirectional diaphragm diameter is 5mm.
The volume of the nothing friction cylinder of described band spring is 100～150mL, and the partial volume that wherein can store liquid is 70～100mL; The range in stiffness of spring is 15～18N/mm, connects an adjustment screw on the spring.
Described spirality pipe caliber is 2～5mm.
Described cam mechanism hub radius far away and nearly hub radius differ 60～90mm, and the angle ∠ AOB between nearly hub radius and the hub radius far away is 135 °.
The invention has the beneficial effects as follows:
Simple in structure, only need common dc micro-motor and simple cam mechanism just can simulate the motion of heart, and the structure of other parts is also simple relatively; It is little to take volume, and all piece volumes are all little, can be integrated in the casing, is convenient to move; Physiological parameter is easy to adjust, can control heart rate by adjusting rotating speed of motor, shrink with the diastolic time ratio and then can reach by the shape of changing cam, the change of vascular compliance then can reach by the rigidity of adjusting spring in addition, and vascular resistance is then controlled by the cross sectional shape of spirality pipe and the length of pipeline.So native system helps simulation circulating system to simple, portable and analog parameter diversified development.
Description of drawings
Fig. 1 is a structural principle sketch map of the present invention.
Fig. 2 is the structural representation of spiral container.
Fig. 3 is unidirectional diaphragm-operated forward junction composition.
Fig. 4 is unidirectional diaphragm-operated side direction structure chart.
Fig. 5 is the structural representation of cam.
Among the figure: 1, spiral container, 2, cylindrical chamber, 3, unidirectional diaphragm, 4, pneumatic tube, 5, the nothing friction cylinder of band spring, 6, spirality pipe, 7, cam mechanism, 8, joint, 3.1, fulcrum, 3.2, the chassis, 3.3, valve, 3.4, spring.
The unit of not marking is mm among the figure.
The specific embodiment
The present invention is described further below in conjunction with drawings and Examples.
As shown in Figure 1, comprise the nothing friction cylinder 5, spirality pipe 6, cam mechanism 7 of spiral container 1 and cylindrical chamber 2, two unidirectional diaphragms, pneumatic tube 4, band spring, two joints 8; The cam rotation of the cam mechanism 7 that is connected with direct current generator, driven member through cam mechanism 7, change the linear reciprocating motion of driven member into, the spiral part of the spiral container 1 of dress liquid was done stretching motion in the driven member top drove, the two ends of the no spiral part of spiral container 1 are respectively with first, the second unidirectional diaphragm is communicated with, the first unidirectional diaphragm is with after the cylindrical chamber 2 of interior dress liquid is communicated with, the cylindrical chamber 2 of interior dress liquid connects an end of spirality pipe 6, the nothing friction cylinder 5 one end fluid connections of the band spring of the second unidirectional diaphragm and interior dress liquid, the liquid of spirality pipe 6 other ends is fluid connection in the nothing friction cylinder 5 of the band spring of pneumatic tube 4 and interior dress liquid, nothing friction cylinder 5 other end spring terminals of the band spring of interior dress liquid are connected with adjustment screw, are respectively equipped with a joint that is communicated with blood pump on the nothing friction cylinder 5 of the cylindrical chamber 2 of interior dress liquid and the band spring of interior dress liquid.
As shown in Figure 1 and Figure 2, described spiral container 1 is made by silica gel, is divided into spiral and no spiral two parts, and wherein the pitch P of spiral part is 10～15mm, and 6～8 teeth are arranged; Bottom surface diameter 30～40mm, volume altogether is 100～150mL, wherein compressible part is divided into 70～100mL.
As Fig. 1, Fig. 3, shown in Figure 4, described unidirectional diaphragm 3 is made of two semicircle valves 3.3 and chassis 3.2, valve is that axial symmetry is installed on the chassis with the diameter, be connected by fulcrum 3.1, valve is around 45～60 ° of rotations of fulcrum, direction of rotation connects a spring 3.4 respectively towards band spring one end on each valve; Chassis 3.2 is bonding with pipeline, and towards there not being friction cylinder 5, whole unidirectional diaphragm diameter is 5mm to first unidirectional diaphragm-operated band spring one end towards spiral container 1, the second unidirectional diaphragm-operated band spring one end.
As shown in Figure 1, the volume of the nothing of described band spring friction cylinder 5 is 100～150mL, and the partial volume that wherein can store liquid is 70～100mL; The range in stiffness of spring is 15～18N/mm, connects an adjustment screw on the spring.
As shown in Figure 1, described spirality pipe 6 calibers are 2～5mm.
As shown in Figure 5, (being minimum point B radius) of (being peak A) of described cam mechanism hub radius far away and nearly hub radius differs 60～90mm, and the angle ∠ AOB between nearly hub radius and the hub radius far away is 135 °.
As shown in Figure 1, direct current generator energising back rotation, the drive cam rotates, cam mechanism 7 changes rotatablely moving of motor into the reciprocating motion of driven member, and driven member is connected with the spiral part of spiral container 1, so just can realize the compression and the extension of spiral container 1, make the liquid in the container discharge or suck.Cam has special shape, and its minimum point B and peak A differ about 20mm, just can realize whenever fighting cardiac output about 70mL in conjunction with the floor space of spiral container 1 and the length of scalable part; In addition
∠ AOB=135 °, when motor 9 rotates counterclockwise with constant angular velocity (about 75rev/min) drive cam 7, may be controlled to the lift of cam 7 and return interval 0.3 and 0.5s, thereby make the time of the compression of spiral container 1 and extension consistent with the contraction and the diastole of natural heart.When spiral container 1 compression, after liquid was discharged from spiral container 1, through the unidirectional diaphragm 3 (preventing that liquid from flowing backwards) of simulation arterial valve, liquid flowed in the nothing friction cylinder 5 of band spring.Because the elasticity of spring, the volume of the nothing friction cylinder 5 of band spring can increase in the short time, then because 1 extension of spiral container, the unidirectional diaphragm 3 of simulation tremulous pulse is closed, spring slowly is returned to original state again, nothing friction cylinder 5 volumes of band spring slowly reduce again, and this whole process is similar to the expansivity of blood vessel, i.e. the compliance of blood vessel.By the definition C=Δ V/ Δ p of compliance and the definition of spring rate, the size of the nothing of combined belt spring friction cylinder 5 can calculate the required rigidity of spring at 15～18N/mm.The rigidity that the expansion screw that connects on the spring can qualitative regulating spring in addition is to change the size of compliance.After flowing out from the outlet of the nothing friction cylinder 5 of band spring, liquid is through one section spirality pipe 6, the diameter of pipeline is about 2～5mm, length has different specifications, so that behind the flow of liquid piping, under the flow about 5L/min, produce the pressure drop of about 10KPa, to reach the effect of simulated blood vessel resistance.Spirality pipe 6 can have different size, and can change, to reach the purpose that changes vascular resistance.Final liquid enters in the cylindrical chamber 2, and this is the storage effect that is used for simulating the atrium.Cylindrical chamber also is connected by a unidirectional diaphragm 3 with spiral container, and unidirectional here diaphragm 3 is used for simulating atrioventricular valves (A V valves).Whole simulation circulating system just constantly circulates according to above-mentioned process under the driving of motor, thereby reaches the sanguimotor effect of simulation human body.
Claims (6)
1, a kind of blood circulation simulating system that is used for testing blood pump performance is characterized in that: the nothing friction cylinder (5), spirality pipe (6), cam mechanism (7), two joints (8) that comprise spiral container (1) and cylindrical chamber (2), two unidirectional diaphragms, pneumatic tube (4), band spring; The cam rotation of the cam mechanism that is connected with direct current generator (7), driven member through cam mechanism (7), change the linear reciprocating motion of driven member into, the spiral part of the spiral container (1) of dress liquid was done stretching motion in the driven member top drove, the two ends of the no spiral part of spiral container (1) are respectively with first, the second unidirectional diaphragm is communicated with, the first unidirectional diaphragm is with after the cylindrical chamber (2) of interior dress liquid is communicated with, the cylindrical chamber (2) of interior dress liquid connects an end of spirality pipe (6), nothing friction cylinder (5) the one end fluid connections of the band spring of the second unidirectional diaphragm and interior dress liquid, the liquid of spirality pipe (6) other end is fluid connection in the nothing friction cylinder (5) of the band spring of pneumatic tube (4) and interior dress liquid, nothing friction cylinder (5) other end spring terminal of the band spring of interior dress liquid is connected with adjustment screw, is respectively equipped with a joint that is communicated with blood pump on the nothing friction cylinder (5) of the band spring of cylindrical chamber of interior dress liquid (2) and interior dress liquid.
2. a kind of blood circulation simulating system that is used for testing blood pump performance according to claim 1, it is characterized in that:: described spiral container (1) is made by silica gel, be divided into spiral and no spiral two parts, wherein the pitch P of spiral part is 10～15mm, and 6～8 teeth are arranged; Bottom surface diameter 30～40mm, volume altogether is 100～150mL, wherein compressible part is divided into 70～100mL.
3. a kind of blood circulation simulating system that is used for testing blood pump performance according to claim 1, it is characterized in that: described unidirectional diaphragm (3) is made of two semicircle valves (3.3) and chassis (3.2), valve is that axial symmetry is installed on the chassis with the diameter, be connected by fulcrum (3.1), valve connects a spring (3.4) respectively around 45～60 ° of rotations of fulcrum on each valve; Chassis (3.2) is bonding with pipeline, and first unidirectional diaphragm-operated band spring one end is towards spiral container (1), and second unidirectional diaphragm-operated band spring one end is towards the nothing friction cylinder (5) of band spring, and whole unidirectional diaphragm diameter is 5mm.
4. a kind of blood circulation simulating system that is used for testing blood pump performance according to claim 1 is characterized in that: the volume of the nothing friction cylinder (5) of described band spring is 100～150mL, and the partial volume that wherein can store liquid is 70～100mL; The range in stiffness of spring is 15～18N/mm, connects an adjustment screw on the spring.
5. a kind of blood circulation simulating system that is used for testing blood pump performance according to claim 1 is characterized in that: described spirality pipe (6) caliber is 2～5mm.
6. a kind of blood circulation simulating system that is used for testing blood pump performance according to claim 1, it is characterized in that: described cam mechanism (7) hub radius far away and nearly hub radius differ 60～90mm, nearly hub radius is 135 ° with the angle ∠ AOB between the hub radius far away.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009101531079A CN101658696B (en) | 2009-09-14 | 2009-09-14 | Blood circulation simulating system used for testing blood pump performance |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009101531079A CN101658696B (en) | 2009-09-14 | 2009-09-14 | Blood circulation simulating system used for testing blood pump performance |
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| CN101658696A true CN101658696A (en) | 2010-03-03 |
| CN101658696B CN101658696B (en) | 2011-12-07 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102949252A (en) * | 2012-10-16 | 2013-03-06 | 北京迈迪顶峰医疗科技有限公司 | Test device for in vitro release and performance simulation of intervening valves |
| CN103990191A (en) * | 2014-06-06 | 2014-08-20 | 中国医学科学院阜外心血管病医院 | Hydraulic performance test system of circulating auxiliary pump |
| CN107091740A (en) * | 2017-06-19 | 2017-08-25 | 苏州同心医疗器械有限公司 | Blood pump endurance testing device |
| CN107822596A (en) * | 2017-10-16 | 2018-03-23 | 中国人民解放军海军总医院 | Chest impact signal simulation generator |
| CN109074753A (en) * | 2016-05-13 | 2018-12-21 | 基诺斯有限公司 | The pulsed analog device of blood vessel |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101176802A (en) * | 2007-11-27 | 2008-05-14 | 上海理工大学 | Pulsation core pump in analog bloodstream revolving |
| CN101380490B (en) * | 2008-09-19 | 2012-09-05 | 北京工业大学 | Artificial heart experimental bench |
-
2009
- 2009-09-14 CN CN2009101531079A patent/CN101658696B/en not_active Expired - Fee Related
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102949252A (en) * | 2012-10-16 | 2013-03-06 | 北京迈迪顶峰医疗科技有限公司 | Test device for in vitro release and performance simulation of intervening valves |
| CN102949252B (en) * | 2012-10-16 | 2015-09-30 | 北京迈迪顶峰医疗科技有限公司 | Can be used for getting involved the in-vitro simulated release of valve and performance testing device |
| CN103990191A (en) * | 2014-06-06 | 2014-08-20 | 中国医学科学院阜外心血管病医院 | Hydraulic performance test system of circulating auxiliary pump |
| CN103990191B (en) * | 2014-06-06 | 2016-03-02 | 中国医学科学院阜外医院 | A kind of hydraulic performance test macro of circulatory assit pump |
| CN109074753A (en) * | 2016-05-13 | 2018-12-21 | 基诺斯有限公司 | The pulsed analog device of blood vessel |
| CN107091740A (en) * | 2017-06-19 | 2017-08-25 | 苏州同心医疗器械有限公司 | Blood pump endurance testing device |
| CN107091740B (en) * | 2017-06-19 | 2023-11-17 | 苏州同心医疗科技股份有限公司 | Blood pump life test device |
| CN107822596A (en) * | 2017-10-16 | 2018-03-23 | 中国人民解放军海军总医院 | Chest impact signal simulation generator |
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| CN101658696B (en) | 2011-12-07 |
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Granted publication date: 20111207 Termination date: 20130914 |