CN102948429A - Livin bacteria removing liquid for marine organism - Google Patents

Abstract

The invention relates to a livin bacteria removing liquid for a marine organism. Effective sterilization components comprise marine organism alpha-spiral bactericidal peptide, seaweed polysaccharide derivatives, bio-enzyme and beta-chitosan quaternization hyaluronic acid derivants, and are prepared by a special process, so that the livin bacteria removing liquid is suitable for being used in restaurants, hotels, hospitals, shopping malls, banks, schools, kindergartens, homes, offices and journey, can be used as an after-wash remedial measure in hospitals, care centers, nursery centers, noshery, kitchens and bathtubs, or is used for sterilization of skin wounds, vulva cleaning and the like; and in addition, the removing liquid is wide in using range, is suitable for sterilizing skins of various field staffs, can effectively control propagation of typhoid fevers, flus, dysentery, pinkeye, gonorrhoea and various kinds of skin diseases, is long in sterilization and bacteriostat time and free of toxin and side effects, and has an efficiency of moisturizing the skins.

Description

Marine bios sterilization solution

Technical field the present invention relates to a kind of marine bios sterilization solution, its effective sterilization component adopts marine organisms alpha-helix cecropin, the algal polysaccharides analog derivative, biology enzyme and β-chitosan quaternary ammonium hyaluronic acid analog derivative is prepared from through special process.Be adapted at restaurant, hotel, hospital, market, bank, school, kindergarten, family, office and use during the journey; Can also in hospital, care centre, child-care center, fast food restaurant, kitchen and the bathroom as the remedial measure after washing one's hands, or be used for skin wound sterilization and vulva cleaning etc., can effectively control typhoid fever, influenza, dysentery, blood-shoot-eye illness, gonorrhoea and various dermopathic propagation, have simultaneously the effect of skin care.

Background technology is between SARS, bird flu, hand-foot-and-mouth disease outburst and Sichuan, Yushu district, Qinghai earthquake period, and the first task of diseases prevention work is Antiepidemic sterilizing.Therefore the disinfectant chemical enterprise of China is emergent has produced the chloride thimerosals such as a lot of 84 thimerosals, Peracetic acid, for very large contribution has been made in diseases prevention between the fight against SARS, bird flu, hand-foot-and-mouth disease and earthquake period.But these sterilized articles therefroms have side effect in various degree, particular time emergent still can, but unsuitable long-term excessive use.The chlorinated product disinfectant that is used for now, active component has clorox, calcium hypochlorite, chlorine dioxide etc.Clorox pH value is higher, so under the condition of the high pH value of northern area raw water quality, high alkalinity, high rigidity, use impurity more.The shortcomings such as high volatility, the noxious odor that in addition, clorox also has is large, sterilizing power is weak and the shelf-life is short, and is unstable.Calcium hypochlorite is commonly referred to bleaching powder at home, refer to the calcium hypochlorite of calcium method explained hereafter, its available chlorine content reaches at most about 40%, calcium chloride content is few, impurity is many, and very dangerous, country even this is made regulation, the calcium hypochlorite goods of calcium method explained hereafter is not accepted marine shipping.And the chlorite in the chlorine dioxide is very easy to produce serious carcinogen with other organic matter.In addition, because domestic manufacturers produce and processing technology is uneven, add the lability of chlorinated product disinfectant itself, the clorox class thimerosal qualification rate on the market is very low.Shandong Province Department of Public Health inspects 231 kinds of anti-(pressing down) bacteria preparations by random samples altogether to the whole province 15 cities (except Dezhou, Binzhou) in November, 2009, and qualified 136 kinds, qualification rate is 58.9%; Jinan, Qingdao and 3 cities, Dezhou inspect 12 kinds of clorox class thimerosals altogether by random samples, and qualified 2 kinds, qualification rate is 16.7%.And the newspaper TV also is of common occurrence to the exposure of 84 thimerosals.Therefore, be badly in need of at present both at home and abroad a kind of novel, safety, thimerosal and overcome above bottleneck problem.

Summary of the invention main points of the present invention are to select suitable component, and carry out rational mixture, through a kind of marine biological disinfectant that heats, emulsion reaction forms.

The prescription following (component and percentage by weight % thereof) that the present invention selects: marine organisms alpha-helix cecropin 6.0-8.0, algal polysaccharides analog derivative 3.0-4.0, biology enzyme 0.5-1.0, β-chitosan quaternary ammonium hyaluronic acid analog derivative 3.0-4.0, polyhexamethylene guanide 0.5-1.0, deionized water adds to 100.

β-chitosan quaternary ammonium hyaluronic acid analog derivative degerming mechanism: under acid condition, β-chitosan quaternary ammonium hyaluronic acid analog derivative has high viscosity and high deacetylized amino Cation adsorption with the bacterium of negative electrical charge, fetter the degree of freedom of microorganism, hindered its metabolism and breeding; Low-molecular-weight chitosan molecule enters in the cell by microorganism wall, hinder the microorganism hereditary password by DNA to the copying of RNA, thereby suppressed the breeding of bacterium.

Algal polysaccharides analog derivative degerming mechanism: the algal polysaccharides analog derivative has absorption, suppress, intervene the electrical of bacterium and virus, the alkaline enzyme of glutinous polysaccharide can destroy-acetylmuramic acid and the β between the NAG-1 in the cell wall, 4 glycosidic bonds can with electronegative bacterium, the direct combination of virus protein, with DNA, RNA, apoprotein forms double salt, algal polysaccharides is to HIV, HSV, togavirus, arenavirus, influenza virus, giant cell virus, the multiple viruses such as the thin virus of reverse transcription and rhabdovirus have obvious inhibitory action, therefore can be applied in the middle of the antiviral therapy medicine.

Marine organisms alpha-helix cecropin degerming mechanism: by in and method and the bacterial cell membrane interaction of electric charge, penetrate killing bacteria with this, greatly reduced the possibility that bacterium produces drug resistance, the degermation of marine organisms alpha-helix cecropin and the kind of peptide and microorganism, alpha-helix cecropin concentration are relevant.Bacterium, fungi, virus, tumour cell are all had obvious lethal effect, and to normal cell without injury effect, and rarely antibody-resistant bacterium produces.

Polyhexamethylene guanide is the high molecular polymer of long-chain, guanidine radicals has very high activity, make polymer become electropositive, usually be electronegative each bacterioid, virus is easy to be adsorbed, then can firmly bacterium be twined, thereby suppress bacterium and viral splitting function, make bacterium, virus lose fecundity, add that polymer molecule has stopped up the respiration channel of microorganism, is choked to death rapidly microorganism.In addition, because the high molecular polymer long chain type structure of polyhexamethylene guanide uniqueness does not contain heterocyclic group, be difficult for being absorbed by animal body inner tissue, thus zooblast there is not toxicity, thus can accomplish human body nontoxic.And its unique physical sterilization mechanism can not develop immunity to drugs by the DNA variation each bacterioid, virus to it, thereby reaches fast, wide spectrum, the stable effect of killing all kinds of bacterial viruses.

Marine organisms of the present invention plain bacteria remover alive, formulated by a certain percentage by β-chitosan quaternary ammonium hyaluronic acid analog derivative, algal polysaccharides analog derivative, marine organisms alpha-helix cecropin and the compositions such as biology enzyme and polyhexamethylene guanide.β-chitosan quaternary ammonium hyaluronic acid analog derivative, algal polysaccharides analog derivative, marine organisms alpha-helix cecropin and biology enzyme are the natural active components of the biological species of natural marine, as main sterilization component, join in proportion in the mixture, purpose is by its characteristic, bacterial propagule and part virus are had preferably killing effect, fungi is also shown stronger killing action.The fragrant board marine organisms in sea plain bacteria remover alive is biological compound bacteria remover, any folk prescription in this component all can not killing bacteria gemma and virus, after forming compound in proportion, by its synergistic characteristic but rapidly killing bacteria gemma and virus, greatly improved sterilization effect.Contain Multiple components in the compound disinfectant, the content ratio of each single component reduces relatively, therefore additive effect has also been played in the side effects such as people's toxicity and excitant less, additive effect refers to the as a whole Disinfection Effect of formulation of disinfectant, greater than the independent Disinfection Effect sum of using of each component.Just can realize this novel quick-acting bactericidal effects according to specific ratio with specific sterilization component is formulated together.Biology enzyme can improve bacteria-eliminating efficacy as the synergistic component in this prescription, makes the effect that just can reach at short notice thorough cleaning.

The preparation method of product of the present invention is:

(1) by proportioning described component is added respectively in the aqueous solution, stir;

(2) by proportioning described component biology enzyme is added stirring, mix;

(3) deionized water adds to 100, stirs; Detect qualified after, packing.

The present invention compares with existing disinfectant has following advantage: (1) sterilization effect is remarkable, and is especially particularly remarkable to staphylococcus aureus and β hemolytic streptococcus; (2) sterilization, inhibition time are long; (2) nontoxic, non-stimulated, non-corrosiveness, smell delicate fragrance; (3) scope of application is wide, is suitable for the disinfection of every field personnel skin; (4) this product is the large molecular glue shaped polymers of marine organisms, and chemical property is very stable, the term of validity 2 years; (5) carry, be convenient to flushing, convenient and practical; (6) technique is simple, and cost is low.

The present invention is described in further detail below in conjunction with embodiment for embodiment:

Be configured according to following table institute column data (percentage by weight %) and affiliated step thereof:

Claims (2)

1. the present invention relates to a kind of marine bios sterilization solution, it is characterized in that having following prescription (component and percentage by weight % thereof): marine organisms alpha-helix cecropin 6.0-8.0, algal polysaccharides analog derivative 3.0-4.0, biology enzyme 0.5-1.0, β-chitosan quaternary ammonium hyaluronic acid analog derivative 3.0-4.0, polyhexamethylene guanide 0.5-1.0, deionized water adds to 100.

2. the preparation method of the described marine bios sterilization solution of claim 1 is characterized in that having following steps:

(1) by proportioning described component is added respectively in the aqueous solution, stir;

(2) by proportioning described component biology enzyme is added stirring, mix;

(3) deionized water adds to 100, stirs; Detect qualified after, packing.