CN102920908B - Traditional Chinese medicine for preventing and curing reaction after radiation therapy for head and neck neoplasm - Google Patents
Traditional Chinese medicine for preventing and curing reaction after radiation therapy for head and neck neoplasm Download PDFInfo
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- CN102920908B CN102920908B CN201210451422.1A CN201210451422A CN102920908B CN 102920908 B CN102920908 B CN 102920908B CN 201210451422 A CN201210451422 A CN 201210451422A CN 102920908 B CN102920908 B CN 102920908B
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Abstract
The invention relates to a traditional Chinese medicine for preventing and curing a reaction after a radiation therapy for head and neck neoplasm, wherein the traditional Chinese medicine is prepared by the following traditional Chinese medicinal materials according to parts by weight: 5-15 parts of radix ophiopogonis, 5-15 parts of asparagus fern, 5-15 parts of root of straight ladybell, 5-15 parts of radix polygonati officinalis, 5-15 parts of honeysuckle, 5-15 parts of medlar and 3-9 parts of chrysanthemum. The traditional Chinese medicine is free from toxicity and harm, simple in preparation and remarkable in treating effect; and the traditional Chinese medicine can be popularized and used in the clinical field.
Description
Technical field
The present invention relates to the post-reacted medicine of a kind of control tumor of head and neck radiotherapy, be specifically related to the post-reacted Chinese medicinal formulae of a kind of control tumor of head and neck radiotherapy.
Background technology
After tumor of head and neck radiotherapy, salivary gland and parotid gland exposure due to patient, there is damage in various degree, salivary gland and parotid secretion are reduced and cause patient's xerostomia, oral mucosa reacts, severe patient need stop radiotherapy, can affect patient treatment effect like this, to patient, bring very big misery.At present, to the oral mucosa reaction after underwent causing after tumour radiotherapy, generally adopt conventional Western medicine to prevent and treat, but this method curative effect of preventing and treating is very undesirable.
Summary of the invention
In order to solve the problems of the technologies described above, the invention provides the post-reacted Chinese medicine of a kind of control tumor of head and neck radiotherapy.
Technical scheme of the present invention is as follows:
The post-reacted Chinese medicine of control tumor of head and neck radiotherapy, is prepared from by the Chinese crude drug of following weight portion:
Radix Ophiopogonis 5-15, Radix Asparagi 5-15, Radix Adenophorae (Radix Glehniae) 5-15, Rhizoma Polygonati Odorati 5-15, Flos Lonicerae 5-15, Fructus Lycii 5-15, Flos Chrysanthemi 3-9.
The present invention adopts and is prepared as follows method: get above each taste, add 10 times, the decocting of 8 times of amounts boils twice, and each 2 hours, merging filtrate, being concentrated into relative density is that 1.05-1.15 is standby.
Medicine of the present invention also can soak and work as tea-drinking with boiled water.
Chinese medicine of the present invention is nontoxic; Radix Asparagi, Radix Ophiopogonis, Radix Adenophorae (Radix Glehniae), Rhizoma Polygonati Odorati, YIN nourishing and the production of body fluid promoting, heat-clearing and toxic substances removing, Fructus Lycii nourishing the liver and kidney; Flos Lonicerae, Flos Chrysanthemi bacteria-inhibiting anti-inflammation; enhancing human body immunity power, each medicine share, and jointly plays the protection parotid gland, salivary gland; regulate immunity; alleviate the effect of oral mucosa reaction after underwent, and its taking convenience, evident in efficacy.
clinical trial
Case: get patient after tumor of head and neck radiotherapy totally 82 examples, be divided into matched group and observation group, every group of 41 examples.Observation group's 41 examples wherein, male 28 examples, female's 13 examples, the age is in 31-64 year, 53 years old mean age.Matched group 41 examples, male 30 examples, female's 11 examples, in 35-72 year, 54 years old mean age, two groups of patients' age, sex are without significant difference, and the oral mucosa reaction after underwent degree of the case of choosing is all at IV degree.
Diagnostic criteria: according to WHO calibration standard, oral mucosa reaction after underwent is divided into 0 degree: normal; 1 degree: hyperemia, salivation reduces, slight xerostomia; II degree: oral cavity is obviously congested, edema, erythema, ulcer, has obvious pain, odynophagia; III degree: oral mucosa is extremely congested, erosion, ulcer increases the weight of, and can only enter spoon meat; IV degree: oral mucosa severe pain, can not take food.
Therapeutic Method:
Matched group adopts the Therapeutic Method of traditional treatment oral mucosa reaction after underwent: in 1% ovocaine 100ml, add gentamycin 160,000 U, dexamethasone 5mg, each 10ml, gargles 3 every day.
Observation group gives medicine of the present invention:
Get 10g Radix Ophiopogonis, Radix Asparagi 10g, Radix Adenophorae (Radix Glehniae) 10g, Rhizoma Polygonati Odorati 10g, Flos Lonicerae 10g, Fructus Lycii 10g, Flos Chrysanthemi 6g, add 10 times, the decocting of 8 times of amounts boils twice, and each 2 hours, merging filtrate, being concentrated into relative density is 1.05-1.15, minute morning, noon and afternoon take for 3 times.
Therapeutic effect:
Take 1 week rear therapeutic effect as follows:
As can be seen from the above table, observation group is by after the treatment of 1 week, oral mucosa reaction after underwent is all lower than II degree, the patient who there is no III degree and IV degree, the case that even has recovery from illness, but the case of matched group III degree and IV degree also accounts for very large ratio, the therapeutic effect of observation group is significantly better than matched group, so the therapeutic effect of the reaction of medicine of the present invention after to tumour radiotherapy is better than the therapeutic effect of common drug to it.
Item security is observed: during taking this prescription, observed case is reacted without significant discomfort.
The specific embodiment
Below in conjunction with embodiment, the present invention is described further.
Embodiment 1
Take 10g Radix Ophiopogonis, Radix Asparagi 10g, Radix Adenophorae (Radix Glehniae) 10g, Rhizoma Polygonati Odorati 10g, Flos Lonicerae 10g, Fructus Lycii 10g, Flos Chrysanthemi 6g, add 10 times, the decocting of 8 times of amounts boils twice, and each 2 hours, merging filtrate, being concentrated into relative density is that 1.05-1.15 is standby.
Embodiment 2
Take 5g Radix Ophiopogonis, Radix Asparagi 5g, Radix Adenophorae (Radix Glehniae) 5g, Rhizoma Polygonati Odorati 5g, Flos Lonicerae 5g, Fructus Lycii 5g, Flos Chrysanthemi 3g, add 10 times, the decocting of 8 times of amounts boils twice, and each two hours, merging filtrate, being concentrated into relative density is that 1.05-1.15 is standby.
Embodiment 3
Radix Ophiopogonis, 15g, Radix Asparagi 15g, Radix Adenophorae (Radix Glehniae) 15g, Rhizoma Polygonati Odorati 15g, Flos Lonicerae 15g, Fructus Lycii 15g, Flos Chrysanthemi 9g, added 10 times, and the decocting of 8 times of amounts boils twice, and each two hours, merging filtrate, being concentrated into relative density is that 1.05-1.15 is standby.
Claims (2)
1. a control tumor of head and neck radiotherapy post-reacted Chinese medicine, is characterized in that, by the Chinese crude drug of following weight portion, is prepared from: Radix Ophiopogonis 5-15, Radix Asparagi 5-15, Radix Adenophorae (Radix Glehniae) 5-15, Rhizoma Polygonati Odorati 5-15, Flos Lonicerae 5-15, Fructus Lycii 5-15, Flos Chrysanthemi 3-9.
2. the post-reacted Chinese medicine of control tumor of head and neck radiotherapy according to claim 1, is characterized in that, adopts and is prepared as follows method preparation: take each taste, add 10 times, the decocting of 8 times of amounts boils twice, each 2 hours, merging filtrate, being concentrated into relative density is that 1.05-1.15 is standby.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210451422.1A CN102920908B (en) | 2012-11-13 | 2012-11-13 | Traditional Chinese medicine for preventing and curing reaction after radiation therapy for head and neck neoplasm |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210451422.1A CN102920908B (en) | 2012-11-13 | 2012-11-13 | Traditional Chinese medicine for preventing and curing reaction after radiation therapy for head and neck neoplasm |
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| Publication Number | Publication Date |
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| CN102920908A CN102920908A (en) | 2013-02-13 |
| CN102920908B true CN102920908B (en) | 2014-03-19 |
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| CN201210451422.1A Expired - Fee Related CN102920908B (en) | 2012-11-13 | 2012-11-13 | Traditional Chinese medicine for preventing and curing reaction after radiation therapy for head and neck neoplasm |
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| CN112569310B (en) * | 2021-02-01 | 2022-02-08 | 重庆市黔江中心医院 | Yin-nourishing and oral liquid for treating radioactive xerostomia |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101549090A (en) * | 2009-05-08 | 2009-10-07 | 沈阳双鼎制药有限公司 | Chinese white olive pieces and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1241620C (en) * | 2002-11-11 | 2006-02-15 | 吉泰安（四川）药业有限公司 | Compound tablet of Chinese medicine for clearing out kakostomia and treating acute pharyngitis and preparation thereof |
| CN102343034B (en) * | 2011-10-14 | 2013-05-22 | 李泽琳 | Composition applied to side effects caused by tumor radiation and pharyngitis as well as preparing method thereof |
| CN102526488B (en) * | 2012-03-23 | 2014-02-12 | 临沂大学 | Traditional Chinese medicine composition with pharynx-cleaning effect |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101549090A (en) * | 2009-05-08 | 2009-10-07 | 沈阳双鼎制药有限公司 | Chinese white olive pieces and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| "中药防治放射性口腔、咽部损伤的研究进展";刘玉芳等;《四川中医》;20071231;第25卷(第7期);第26-28页 * |
| "中药防治放射性口腔干燥症用药规律的探讨";张燕等;《东南国防医药》;20120120;第14卷(第1期);第39-41页 * |
| 刘玉芳等."中药防治放射性口腔、咽部损伤的研究进展".《四川中医》.2007,第25卷(第7期),第26-28页. |
| 张燕等."中药防治放射性口腔干燥症用药规律的探讨".《东南国防医药》.2012,第14卷(第1期),第39-41页. |
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