CN102908510A

CN102908510A - Decoction for treating knee osteoarthritis

Info

Publication number: CN102908510A
Application number: CN2012104529852A
Authority: CN
Inventors: 牛福文
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-11-14
Filing date: 2012-11-14
Publication date: 2013-02-06
Anticipated expiration: 2032-11-14
Also published as: CN103536755A; CN103536755B; CN102908510B

Abstract

The invention relates to a decoction for treating knee osteoarthritis. The decoction is prepared by the following materials by weight: 5-10 parts of paris polyphylla, 5-15 parts of cortex dictamni, 1 part to 15 parts of girald pteroxygonum root, 3-8 parts of radix ophiopogonis, 1 part to 15 parts of folium isatidis, 3-10 parts of rabdosia lophanthide, 5-10 parts of polygala tenuifolia, 3-8 parts of semen raphani, 5-10 parts of honeysuckle, 10-20 parts of leonurus, 10-20 parts of thunder god vine, 20-40 parts of uniflower swisscentaury root, 5-15 parts of carpet bugle, 20-30 parts of white mulberry root bark, 10-30 parts of radix clematidis, 1 part to 10 parts of rhizoma alismatis and 200-700 parts of water. The decoction for treating knee osteoarthritis has the advantages of being low in cost, easy to prepare, small in toxic and side effect and remarkable in treatment effect.

Description

A kind of decoction for the treatment of knee joint osseous arthritis

Technical field

The present invention relates to the orthopaedics therapy field, relate in particular to a kind of decoction for the treatment of knee joint osseous arthritis.

Background technology

Knee joint osseous arthritis is the commonly encountered diseases of Orthopaedics Clinic, and clinical manifestation is kneed swelling, pain, and can there be joint deformity in the later stage, patient walking, upper downstairs, has squatted difficultly, quality of life is had a strong impact on.Primary disease more than 60 years old the crowd have 49% primary disease occurs, women's prevalence is higher than the male.The pathogenic factor more complicated of knee joint osseous arthritis mainly comprises the stress equilibrium imbalance of wound, obesity, age, over loading motion, sex, environment, biomechanics aspect etc., and wherein, middle-aged and elderly people is the colony of mainly falling ill.Its basic pathology is changed to that articular cartilage is softening, osteosclerosis under the cartilage surface, synovitis, Secondary cases joint capsule fibre modification and around the spasm of muscle.The past expectant treatment is mainly with oral analgesic, analgesia, anti-inflammatory drug, or intraarticular injection glucocorticoid medicine, though certain clinical efficacy is arranged, but paresthesia alleviateding time is short, and its untoward reaction is difficult to again avoid such as prolonged application, especially intraarticular injection, puncture easily causes infecting frequently, more easily cause chondrocyte to destroy, thereby be unfavorable for the reparation of articular cartilage, the arthritic development process of accelerated bone.Therefore, in the urgent need to seeking a kind of medicament for the treatment of knee joint osseous arthritis.

Summary of the invention

The purpose of this invention is to provide a kind of decoction for the treatment of knee joint osseous arthritis.

In order to realize purpose of the present invention, the invention provides a kind of decoction for the treatment of knee joint osseous arthritis, it is to be made by the material of following weight proportioning: Rhizoma Paridis 5-10 part, Cortex Dictamni 5-15 part, Radix Polygoni Ciliinerve 1-15 part, Radix Ophiopogonis 3-8 part, Folium Isatidis 1-15 part, Herba Rabdosiae Lophanthoidis 3-10 part, Radix Polygalae 5-10 part, Semen Raphani 3-8 part, Flos Lonicerae 5-10 part, Herba Leonuri 10-20 part, Radix Tripterygii Wilfordii 10-20 part, Radix Rhapontici 20-40 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 5-15 part, Cortex Mori 20-30 part, Radix Clematidis 10-30 part, Rhizoma Alismatis 1-10 part and water 200-700 part.

Preferably, the decoction for the treatment of knee joint osseous arthritis of the present invention is to be made by the material of following weight proportioning: 500 parts in 5 parts of Rhizoma Paridis, 10 parts of Cortex Dictamni, 10 parts of Radix Polygoni Ciliinerves, 5 parts of Radix Ophiopogonis, 10 parts of Folium Isatidiss, 5 parts of Herba Rabdosiae Lophanthoidiss, 5 parts of Radix Polygalaes, 5 parts of Semen Raphanis, 10 parts of Flos Loniceraes, 15 parts of Herba Leonuris, 15 parts of Radix Tripterygii Wilfordiis, 30 parts of Radix Rhapontici, 10 parts of Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.)s, 25 parts of Cortex Mori, 20 parts of Radix Clematidis, 5 parts of Rhizoma Alismatis and water.

The decoction for the treatment of knee joint osseous arthritis of the present invention has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect is showing.

The specific embodiment

Below the invention will be further described for the description by the specific embodiment, but this is not to be limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.

Embodiment 1: the preparation of decoction of the present invention

Take by weighing Rhizoma Paridis 50 gram, Cortex Dictamni 100 grams, Radix Polygoni Ciliinerve 100 grams, Radix Ophiopogonis 50 gram, Folium Isatidis 100 grams, Herba Rabdosiae Lophanthoidis 50 grams, Radix Polygalae 50 grams, Semen Raphani 50 grams, Flos Lonicerae 100 grams, Herba Leonuri 150 grams, Radix Tripterygii Wilfordii 150 grams, Radix Rhapontici 300 grams, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 100 grams, Cortex Mori 250 grams, Radix Clematidis 200 grams, Rhizoma Alismatis 50 grams and water 5000 grams, place in the flask of sealing, heating is 5 hours under 90 ℃ water-bath, be cooled to room temperature, filter, collect filtrate and namely get decoction of the present invention.

Experimental example

Diagnosis basis

1. the gonalgia often is the persistence dull pain, generally in the motion postemphasis, alleviates after the rest.2. knee joint often has deadlocked phenomenon, namely rests on for a long time on some positions, and a kind of stiff sense is arranged during motion, movable rear improvement the, and the phenomenon that has soft lower limb to want to fall.3. knee joint function is slight or moderate is limited, walking disorder, the difficulty of squatting down.4. the person that has the hydrops, floating patella test is positive.5. x-ray knee joint anterioposterior and lateral film shows: the joint space narrows down, subchondral bone matter edge hypertrophy, or the edge, joint has bony spur to form.6. lab testing: rheumatoid factor negative, erythrocyte sedimentation rate, antistreptolysin O normal (Zhu Hanzhang. pin cutter medical science. Beijing: China Traditional Chinese Medicine Publishing House, 2004:538-540.).

Physical data

Choose the patient's physical data that meets above-mentioned standard and originally organize in 84 examples, male 35 examples, women 49 examples, age 37-78 year, 56.2 years old mean age.The course of disease is the shortest 3 months, and is the longest 1 year, bilateral knee joint 32 examples, and unilateral knee joint 52 examples, above patient all passes through medicine, acupuncture, massage, the method such as force on treatment, poor effect.

Take the decoction of preparation among the embodiment 1, three times on the one, each 100 milliliters.30 days is 1 course for the treatment of.

The standard of curative effect evaluation

Cure: transference cure after the treatment, pressure pain point disappears, and it is normal that knee joint function recovers.Produce effects: treatment posterior joint pain, stiff and swelling situation obviously alleviate, and it is normal that function is recovered substantially.Effectively: treatment posterior joint pain, stiff and swelling situation alleviate, but still pain, and function is slightly limited.Invalid: as to compare before symptom and the art without improving after the treatment.

Through treatment, find the transference cure of 84 examples, pressure pain point disappears, and it is normal that knee joint function recovers.Therefore, the standard that all meets healing.And in therapeutic process, do not find obvious untoward reaction.

Typical case's pathology

Sui, the woman, 37 years old, left knee joint persistence dull pain in the motion postemphasis, alleviated after the rest.X-ray knee joint anterioposterior and lateral film shows subchondral bone matter edge hypertrophy.On inspection, prove conclusively and be knee joint osseous arthritis.Take the decoction of preparation among the embodiment 1, three times on the one, each 100 milliliters, treated continuously 30 days.Patient's transference cure after the treatment, pressure pain point disappears, and it is normal that knee joint function recovers.

Zhang, the man, 41 years old, two knee joints often had deadlocked phenomenon, rested on for a long time on some positions, and a kind of stiff sense is arranged during motion, movable rear improvement the, and the phenomenon that has soft lower limb to want to fall, walking disorder, the difficulty of squatting down, the gonalgia.On inspection, prove conclusively and be knee joint osseous arthritis.Take the decoction of preparation among the embodiment 1, three times on the one, each 100 milliliters, treated continuously 30 days.Patient's transference cure after the treatment, pressure pain point disappears, and it is normal that knee joint function recovers.

The king so-and-so, the woman, 51 years old, knee joint function was slight or moderate is limited, walking disorder, the difficulty of squatting down, the gonalgia.On inspection, prove conclusively and be knee joint osseous arthritis.Take the decoction of preparation among the embodiment 1, three times on the one, each 100 milliliters, treated continuously 30 days.Patient's transference cure after the treatment, pressure pain point disappears, and it is normal that knee joint function recovers.

Claims

1. decoction for the treatment of knee joint osseous arthritis is characterized in that it is to be made by the material of following weight proportioning: Rhizoma Paridis 5-10 part, Cortex Dictamni 5-15 part, Radix Polygoni Ciliinerve 1-15 part, Radix Ophiopogonis 3-8 part, Folium Isatidis 1-15 part, Herba Rabdosiae Lophanthoidis 3-10 part, Radix Polygalae 5-10 part, Semen Raphani 3-8 part, Flos Lonicerae 5-10 part, Herba Leonuri 10-20 part, Radix Tripterygii Wilfordii 10-20 part, Radix Rhapontici 20-40 part, Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.) 5-15 part, Cortex Mori 20-30 part, Radix Clematidis 10-30 part, Rhizoma Alismatis 1-10 part and/or water 200-700 part.

2. the decoction for the treatment of knee joint osseous arthritis according to claim 1 is characterized in that it is to be made by the material of following weight proportioning: 500 parts in 5 parts of Rhizoma Paridis, 10 parts of Cortex Dictamni, 10 parts of Radix Polygoni Ciliinerves, 5 parts of Radix Ophiopogonis, 10 parts of Folium Isatidiss, 5 parts of Herba Rabdosiae Lophanthoidiss, 5 parts of Radix Polygalaes, 5 parts of Semen Raphanis, 10 parts of Flos Loniceraes, 15 parts of Herba Leonuris, 15 parts of Radix Tripterygii Wilfordiis, 30 parts of Radix Rhapontici, 10 parts of Herba ajugae ciliatae (Herba Ajugae Ajuga ciliata Bge.)s, 25 parts of Cortex Mori, 20 parts of Radix Clematidis, 5 parts of Rhizoma Alismatis and/or water.