CN103142748A - Traditional Chinese medicine for treating degenerative joint disease - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating a degenerative joint disease. The invention comprises traditional Chinese medicine raw material medicines such as prepared rehmannia, woodwardia, codonopsis root, angelica, chiang-huo, tu-huo, ledebouriella root, Sichuan aconite main root (prepared), wild aconite (prepared), dipsacus and cyathula root. The traditional Chinese medicine provided by the invention has the efficacies of tonifying liver and kidney, regulating qi and blood, unblocking the meridians, dispelling the cold-dampness in order to treat the degenerative joint disease; and has been used in clinical applications for many years, and the effect is significant.

Description

A kind of Chinese medicine for the treatment of osteoarthritis

Technical field

The present invention relates to a kind of Chinese medicine for the treatment of osteoarthritis, more specifically say a kind of invigorating the liver and kidney that has, QI and blood regulating, the meridian dredging, the effect of dispelling cold and dampness is with the Chinese medicine for the treatment of osteoarthritis.Belong to field of medicaments.

Background technology

Osteoarthritis refers to that some row degeneration that human body occurs change, as arthralgia, stiff and limitation of activity etc.Degenerative osteoarthritis comprises Articular cartilage degeneration and hyperosteogeny (bony spur and hyperosteogeny), is a kind of comprehensive disease.It is mainly hyperosteogeny in the joint or the formation of bony spur, and clinical manifestation is mainly upper painstaking downstairs, and knee feels cold, and in the time of acute attack, main manifestations is local red and swollen heat pain.

Osteoarthritis with the be full of cracks of articular cartilage generation diffusivity, fibrosis with take off the one group of clinical syndrome that loses and be changed to because of the osseous tissue hypertrophy feature, is to be more common in later chronic progressive external joint diseases of middle age.One of China's four large senile disease, its high prevalence, high disability rate and high medical expense have had a strong impact on the development of quality of life of patients and social productive forces.Along with the aging of China's population, the prevalence of osteoarthritis is up to 8.3% of total number of persons.There is no at present the Therapeutic Method of satisfactory effect.

Osteoarthritis belongs to the category of Chinese medicine " arthromyodynia ", is referred to as mainly with " rheumatism involving the bone " clinically.Motherland's medical science is thought primary disease and worn with age, long-term strain, and the affection of exogenous wind-cold damp is relevant.After middle age, caused by liver and kidney deficiency, suffering from a deficiency of the kidney can not main bone, and deficiency of the liver is difficult nourishing muscle and tendon, and muscles and bones mistake is supported, and is this pathogenetic pathologic basis." Plain Questions is declared five gas pieces of writing ": " five kinds of impairments caused by overstrain ... prolonged standing injuring bones, prolonged walking injuring tendons ".Long-term strain or wound coup injury muscles and bones are described, stagnation of QI and blood is obstructed, and through the BI-syndrome involved the blood vessels resistance, stagnation of QI and blood may bring about pain forms primary disease.

This disease sickness rate raises with age growth, and is according to investigations, present more than 200,000,000 in population in the U.S., osteoarthritis 4,500 ten thousand is just arranged, and sickness rate accounts for 20% of total population, and proportion is higher in the old people, more than 50 years old, in the crowd, the prevalence of OA is only second to cardiovascular disease, occupies second.In China, show according to Epidemiological study, in the crowd of 55～64 years old, sickness rate reaches 40%, and over-65s crowd's prevalence reaches 60%～90%.Along with permanent enforcement and the economic development of family planning policy, China has entered aging society, and the sickness rate of osteoarthritis also will be more and more higher, and this is the serious harm people's life, health not only, also will cause very large burden to society.

Medicine base of the present invention with Chinese medical theory, is the Therapeutic Principle with " invigorating the liver and kidney, QI and blood regulating, the meridian dredging, dispelling cold and dampness ", through systematic study, science compatibility, has developed a kind of pure Chinese medicine for the treatment of osteoarthritis.

Summary of the invention

Purpose of the present invention just is to provide a kind of Chinese medicine for the treatment of osteoarthritis.

For achieving the above object, the Chinese medicine for the treatment of osteoarthritis provided by the invention is prepared from by the processing of the crude drug of following weight parts:

Radix Rehmanniae Preparata 5-10 part Rhizoma Cibotii 5-10 part Radix Codonopsis 5-8 part Radix Angelicae Sinensis 10-15 part

Rhizoma Et Radix Notopterygii 2-5 part Radix Angelicae Pubescentis 3-8 part Radix Saposhnikoviae 2-5 part Radix Aconiti (system) 1-3 part

Radix Aconiti Kusnezoffii (system) 1-3 part Radix Dipsaci 2-5 part Radix Cyathulae 5-10 part.

Preferred plan is prepared from by the processing of the crude drug of following weight parts:

12 parts of 6 parts of Radix Angelicae Sinensis of 8 parts of Radix Codonopsis of 8 parts of Rhizoma Cibotii of Radix Rehmanniae Preparata

2 parts of Rhizoma Et Radix Notopterygii 3 parts of Radix Angelicae Pubescentiss, 3 portions of Radix Aconitis of 5 parts of Radix Saposhnikoviaes (system)

8 parts of 3 portions of Radix Cyathulaes of 2 parts of Radix Dipsacis of Radix Aconiti Kusnezoffii (system).

A kind of Chinese medicine for the treatment of osteoarthritis of the present invention can be prepared into any existing clinical applicable dosage form in capsule, tablet, granule, oral liquid, pill.

Described weight portion can be the weight metering units such as gram, two, jin, kilogram, ton.

Why the present invention selects above-mentioned medical material as raw material, is because they have following effect:

Radix Rehmanniae Preparata: strongly invigorating primordial QI, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, calming the nerves increases intelligence.Can be used for the deficiency of vital energy and want to take off, deficiency of spleen-QI, the lung qi virtual loss, Tianjin wound is thirsty, quenches one's thirst, irritability, insomnia and dreamful sleep is palpitated with fear forgetful, the cards such as blood deficiency sexual impotence.

Rhizoma Cibotii: invigorating the liver and kidney, strong spinal column, wind-damp dispelling.Be used for spinal column aching and limp, weakness of the lower extremities, rheumatic arthralgia.

Radix Codonopsis: invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting is used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst.

Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.

Rhizoma Et Radix Notopterygii: cold expelling, dispel the wind, dehumidifying, pain relieving.Be used for the anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.

Radix Angelicae Pubescentis: expelling wind and removing dampness, numbness relieving and pain relieving.Be used for anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache.

Radix Saposhnikoviae: inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.Be used for headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.

Radix Aconiti (system): expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.

Radix Aconiti Kusnezoffii (system): expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.

Radix Dipsaci: invigorating the liver and kidney, bone and muscle strengthening, continuous folding wound, only metrorrhagia.Be used for soreness of the waist and knees, rheumatic arthralgia, the metrorrhagia warp is many, vaginal bleeding during pregnancy hematochezia, injury from falling down.

Radix Cyathulae: eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.Be used for the amenorrhea lump in the abdomen, retention of placenta, arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.

Pharmaceutical composition provided by the invention has invigorating the liver and kidney, QI and blood regulating, and the meridian dredging, the effect of dispelling cold and dampness is with the Chinese medicine for the treatment of osteoarthritis.

Clinical case:

Zhang, women, 68 years old, retired worker.On January 22nd, 2009 came here medical more than right gonalgia May.The right gonalgia of main suit, especially with stair activity and when squatting down for very, when movable, the ossa articularia sound is arranged, the walking for a long time of can not standing for a long time, motion and Changes in weather postemphasis, rest alleviates, have a medical check-up: the slight swelling of right knee joint, periarticular all has tenderness in various degree, the slight atrophy of quadriceps femoris, McMurray sign (±), drawer test (-), floating patella test (-), grinding test (±), medial collateral ligament separation test (-).Lab testing: erythrocyte sedimentation rate 16 mm/h, rheumatoid factor negative, anti-" O " negative, the inspection of right knee joint X sheet is shown: right knee space narrows down, the intercondyloid spine hypertrophy, patella and tibia edge have hyperosteogeny to form.Be diagnosed as: right knee joint osseous arthritis.After giving Chinese medicine of the present invention and taking 3 courses for the treatment of, treat 3 the course for the treatment of clinical symptom disappearance, it is normal that Ambulatory Activity recovers substantially.Advise the patient to strengthen the suitable functional exercise of right knee joint, follow up a case by regular visits to and had no recurrence in 1 year.

The specific embodiment

The specific embodiment that the below adopts describes the present invention, and the description of this part is only exemplary and explanatory, should any restriction not arranged to protection scope of the present invention.

Embodiment 1

Radix Rehmanniae Preparata 5-10 part Rhizoma Cibotii 5-10 part Radix Codonopsis 5-8 part Radix Angelicae Sinensis 10-15 part

Rhizoma Et Radix Notopterygii 2-5 part Radix Angelicae Pubescentis 3-8 part Radix Saposhnikoviae 2-5 part Radix Aconiti (system) 1-3 part

Radix Aconiti Kusnezoffii (system) 1-3 part Radix Dipsaci 2-5 part Radix Cyathulae 5-10 part

Embodiment 2

Radix Rehmanniae Preparata 5-10 part Rhizoma Cibotii 5-10 part Radix Codonopsis 5-8 part Radix Angelicae Sinensis 10-15 part

Rhizoma Et Radix Notopterygii 2-5 part Radix Angelicae Pubescentis 3-8 part Radix Saposhnikoviae 2-5 part Radix Aconiti (system) 1-3 part

Radix Aconiti Kusnezoffii (system) 1-3 part Radix Dipsaci 2-5 part Radix Cyathulae 5-10 part

Embodiment 3

12 parts of 6 parts of Radix Angelicae Sinensis of 8 parts of Radix Codonopsis of 8 parts of Rhizoma Cibotii of Radix Rehmanniae Preparata

2 parts of Rhizoma Et Radix Notopterygii 3 parts of Radix Angelicae Pubescentiss, 3 portions of Radix Aconitis of 5 parts of Radix Saposhnikoviaes (system)

8 parts of 3 portions of Radix Cyathulaes of 2 parts of Radix Dipsacis of Radix Aconiti Kusnezoffii (system)

The application of above-mentioned composition aspect the treatment osteoarthritis.

Above-mentioned composition can be made any existing clinical applicable dosage form in capsule, tablet, granule, oral liquid, pill according to prior art.

Claims (3)

1. Chinese medicine for the treatment of osteoarthritis is characterized in that being prepared from by the crude drug processing of following weight parts:

Radix Rehmanniae Preparata 5-10 part Rhizoma Cibotii 5-10 part Radix Codonopsis 5-8 part Radix Angelicae Sinensis 10-15 part

Rhizoma Et Radix Notopterygii 2-5 part Radix Angelicae Pubescentis 3-8 part Radix Saposhnikoviae 2-5 part Radix Aconiti (system) 1-3 part

Radix Aconiti Kusnezoffii (system) 1-3 part Radix Dipsaci 2-5 part Radix Cyathulae 5-10 part.

2. a kind of Chinese medicine for the treatment of osteoarthritis according to claim 1 is characterized in that being prepared from by the crude drug processing of following weight parts:

12 parts of 6 parts of Radix Angelicae Sinensis of 8 parts of Radix Codonopsis of 8 parts of Rhizoma Cibotii of Radix Rehmanniae Preparata

2 parts of Rhizoma Et Radix Notopterygii 3 parts of Radix Angelicae Pubescentiss, 3 portions of Radix Aconitis of 5 parts of Radix Saposhnikoviaes (system)

8 parts of 3 portions of Radix Cyathulaes of 2 parts of Radix Dipsacis of Radix Aconiti Kusnezoffii (system).

3. one of them described a kind of Chinese medicine for the treatment of osteoarthritis according to claim 1 and 2, is characterized in that, preparation is any existing clinical applicable dosage form in capsule, tablet, granule, oral liquid, pill.