CN104013687B - A kind of Chinese medicine suppository for the treatment of prolapse of lumbar intervertebral disc - Google Patents
A kind of Chinese medicine suppository for the treatment of prolapse of lumbar intervertebral disc Download PDFInfo
- Publication number
- CN104013687B CN104013687B CN201410292138.3A CN201410292138A CN104013687B CN 104013687 B CN104013687 B CN 104013687B CN 201410292138 A CN201410292138 A CN 201410292138A CN 104013687 B CN104013687 B CN 104013687B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- treatment
- radix
- prolapse
- suppository
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of Chinese medicine suppository for the treatment of prolapse of lumbar intervertebral disc, belong to Chinese medicine extract and prepare suppository technical field.It is made up of Chinese medicines such as processing Radix Aconiti, Radix Aconiti Kusnezoffii Preparata, HUOXUETENG, Radix Angelicae Sinensis, Typhonium flagelliforme (Lodd.) Blume, Radix Achyranthis Bidentatae, Herba Taxilli, Radix Clematidis, Rhizoma Corydalis, Eupolyphaga Seu Steleophaga, Scorpio, Radix Angelicae Pubescentis, Scolopendra.The present invention is based on motherland's medical science to the pathogenetic research of lumbar spondylosis and Therapeutic Principle, the prescription compatibility that the scientific achievement with reference to modern Chinese medicine theoretical research is carried out, and has expelling wind and removing dampness, dispelling cold by warming the meridian, dissipating blood stasis dredging collateral and blood is regulated the flow of vital energy, effect of alleviating pain and detumescence.The Chinese medicine suppository of this treatment prolapse of lumbar intervertebral disc, by Chinese medicine large for the oral toxicity for the treatment of prolapse of lumbar intervertebral disc, utilizes suppository rectal absorption, without the first pass effect of liver.Thoroughly solve the toxic and side effects of toxic traditional Chinese medicine, improve the bioavailability of medicine, make the present invention have treatment painful few, easy to use, safe and effective, reach the effect for the treatment of both the principal and secondary aspects of a disease.
Description
Technical field
The present invention relates to a kind of Chinese medicine suppository for the treatment of prolapse of lumbar intervertebral disc, belong to Chinese medicine extract and prepare suppository technical field.
Background technology
Prolapse of lumbar intervertebral disc is mainly relaxed by the fibrosus ligament swelling of intervertebral and causes vertebral pulp to deviate to cause, and has a strong impact on the normal work of people, study, work and entertainment life.At present for means such as the treatment that prolapse of lumbar intervertebral disc is main are massage, massage, acupuncture, traction, plaster, but can only mitigate the disease, therapy discontinued will recur.Also to have in addition and adopt operative treatment, but have a big risk due to operative treatment, costly, patient is painful large, and a lot of patient does not take the method for operative treatment.
Summary of the invention
The object of the invention is to, for above-mentioned the deficiencies in the prior art, a kind of pathogeny for prolapse of lumbar intervertebral disc is provided, utilizes Chinese medicine expelling wind and removing dampness, tendons relaxing and meridians dredging, dispelling cold by warming the meridian, has blood yiqi, invigorating the liver and kidney, strong waist knee joint, blood circulation promoting regulates qi, the effects such as removing toxic substances pain relieving, reach the object for the treatment of both the principal and secondary aspects of a disease; And administration is simple, easy to prepare, the Chinese medicine suppository of the treatment prolapse of lumbar intervertebral disc do not recurred after treatment.
The present invention realizes above-mentioned purpose by the following technical solutions:
The Chinese medicine suppository of this treatment prolapse of lumbar intervertebral disc, is characterized in that: it is made up of the Chinese medicine of following weight percentage ratio:
Process Radix Aconiti 3.92% Radix Aconiti Kusnezoffii Preparata 3.92% HUOXUETENG 5.88%
Radix Angelicae Sinensis 5.88% Typhonium flagelliforme (Lodd.) Blume 5.88% Radix Achyranthis Bidentatae 5.88%
Herba Taxilli 9.80% Radix Clematidis 9.80% Rhizoma Corydalis 30.94%
Eupolyphaga Seu Steleophaga 5.88% Scorpio 5.88% Radix Angelicae Pubescentis 5.88%
Scolopendra 0.46%.
Above-mentioned technical solution of the present invention, to the pathogenetic research of lumbar spondylosis and Therapeutic Principle based on motherland's medical science, with reference to the prescription compatibility that the scientific achievement of modern Chinese medicine theoretical research is carried out, its prescription has expelling wind and removing dampness, dispelling cold by warming the meridian, dissipating blood stasis dredging collateral and blood is regulated the flow of vital energy, effect of alleviating pain and detumescence, extract the effective ingredient of medicine, reach the object for the treatment of lumbar spondylosis.
Preparation method of the present invention: cleaned by above-mentioned medical material, drain, adds the edible ethanol of 95% of crude drug quality quintuple, extracts one hour, is concentrated into the extractum that proportion is 1.20 ~ 1.25 after filtration; Then with extractum mass ratio be the Polyethylene Glycol of 49.5 ℅, after the glycerol of the glyceryl monostearate of 49.5 ﹪ and 1.0 ℅ mixes with extractum, be heated to 50 DEG C ~ 55 DEG C, melt stir after, fill in suppository shell bag forming, under being stored in 5 DEG C ~ 28 DEG C temperature environments.
Usage and dosage of the present invention: suppository is taken out and fills in anal 1 ~ 2cm place; Sooner or later once, within 8 ~ 10 days, be a course for the treatment of, the lighter can cure a course for the treatment of, and severe one can be cured 2 ~ 3 courses for the treatment of.
Points for attention: anemia of pregnant woman and gynecologic menstrual are cautious use of.
The present invention's beneficial effect is compared with prior art:
The Chinese medicine suppository of this treatment prolapse of lumbar intervertebral disc, by Chinese medicine large for the oral toxicity for the treatment of prolapse of lumbar intervertebral disc, utilizes suppository rectal absorption, without the first pass effect of liver.Thoroughly solve the toxic and side effects of toxic traditional Chinese medicine, improve the bioavailability of medicine, make the present invention have treatment painful few, easy to use, safe and effective, reach the effect for the treatment of both the principal and secondary aspects of a disease.
Detailed description of the invention
The Chinese medicine suppository of this treatment prolapse of lumbar intervertebral disc is made up of the Chinese medicine of following weight percentage ratio:
Process Radix Aconiti 3.92% Radix Aconiti Kusnezoffii Preparata 3.92% HUOXUETENG 5.88%
Radix Angelicae Sinensis 5.88% Typhonium flagelliforme (Lodd.) Blume 5.88% Radix Achyranthis Bidentatae 5.88%
Herba Taxilli 9.80% Radix Clematidis 9.80% Rhizoma Corydalis 30.94%
Eupolyphaga Seu Steleophaga 5.88% Scorpio 5.88% Radix Angelicae Pubescentis 5.88%
Scolopendra 0.46%.
Preparation method of the present invention: cleaned by above-mentioned medical material, drain, adds the edible ethanol of 95% of crude drug quality quintuple, extracts one hour, is concentrated into the extractum that proportion is 1.20 ~ 1.25 after filtration.Then with extractum mass ratio be the Polyethylene Glycol of 49.5 ℅, after the glycerol of the glyceryl monostearate of 49.5 ﹪ and 1.0 ℅ mixes with extractum, be heated to 50 DEG C ~ 55 DEG C, melt stir after, fill in suppository shell bag forming, under being stored in 5 DEG C ~ 28 DEG C temperature environments.
The present invention is by having carried out the clinical observation of system to 120 routine patients, and it is as follows to the therapeutic effect data of prolapse of lumbar intervertebral disc:
Clinical observation patient: male 71 example, women 49 example, max age 69 years old, minimal ages 25 years old, the shortest person of the course of disease 5 months, most elder is 10 years.
Efficacy assessment standard: evaluate with reference to relevant criterion of therapeutical effect in " the clinical guidance principle of new Chinese medicine treatment prolapse of lumbar intervertebral disc " of Ministry of Public Health formulation in 1993 and " the disease of tcm Standardization of diagnosis and curative effect " of State Administration of Traditional Chinese Medicine's issue:
Clinical recovery: lumbago and skelalgia disappears substantially, Negative straight-leg raising test, recovers normally to work.
Effective: flank pain partial disappearance, without obvious pressure pain point, Negative straight-leg raising test, basic recovery normally works.
Effective: slight lumbago and skelalgia, straight-leg raising test probable positive, part is resumed work.
Invalid: lumbago and skelalgia is without improvement, and straight-leg raising test is positive, not competent work.
Clinical efficacy effect sees the following form:
The present invention treats intervertebral disk hernia case 120 example, analysis of results table
Below by a specific embodiment, the present invention will be further described
To take the raw material of Chinese medicine of 100kg.
Raw material of Chinese medicine is taken by following each raw material and weight:
Process Radix Aconiti 3.92kg, Radix Aconiti Kusnezoffii Preparata 3.92kg, HUOXUETENG 5.88kg, Radix Angelicae Sinensis 5.88kg, Typhonium flagelliforme (Lodd.) Blume 5.88kg, Radix Achyranthis Bidentatae 5.88kg, Herba Taxilli 9.80kg, Radix Clematidis 9.80kg, Rhizoma Corydalis 30.94kg, Eupolyphaga Seu Steleophaga 5.88kg, Scorpio 5.88Kg, Radix Angelicae Pubescentis 5.88kg, Scolopendra 0.46kg.
Preparation method:
Above-mentioned raw materials is cleaned, drains, drop in extraction pot, add the edible ethanol of 500kg95%, extract one hour, after filtration, filtrate is concentrated into the extractum that proportion is 1.20 ~ 1.25.Again by Polyethylene Glycol 7.425kg, glyceryl monostearate 7.425kg, glycerol 0.5kg and above-mentioned concentrated extract Hybrid Heating, melt, stir, fill, in the suppository shell bag of 2g, is stored in 5 ~ 28 degree of environment, and every piece containing extractum 1g.
Model case:
Case 1:
High certain female 45 years old Hubei Province people from Gongan County, Jingzhou City, 2010.7 the moon goes to a doctor, CT diagnoses L3-L4 L4-L5 intervertebral disk hernia, numbness of lower limbs, and slight illness unbearably, walking disorder, hospitalization, adopt vertebra health bolt of dashing forward to treat a course for the treatment of, symptom takes a turn for the better to some extent, after two courses for the treatment of, symptom disappears completely, does not send out so far.
Case 2:
Zhang female 32 years old Hubei Province people from Gongan County, Jingzhou City, in May, 2004 is L3-L4 L4-L5 intervertebral disk hernia through CT examination, once adopts other treatment mode, disease amelioration, but easily recur, in October, 2010 goes to a doctor, vertebra is adopted to dash forward after health bolt treats a course for the treatment of, symptom is clearly better, after 2 to 3 courses for the treatment of, symptom disappears completely, follows up a case by regular visits to after 1 year, is without pain, freely, readme is fully recovered in activity.
The above is preferred embodiment of the present invention, above-mentioned illustrating does not do any pro forma restriction to flesh and blood of the present invention, any simple modification that person of an ordinary skill in the technical field has done above detailed description of the invention according to the technical spirit of invention after having read this description or distortion, and may utilize in the scope of technical scheme of above-mentioned announcement, and do not deviate from the spirit and scope of the invention.
Claims (1)
1. treat a Chinese medicine suppository for prolapse of lumbar intervertebral disc, it is characterized in that: it is made up of the Chinese medicine of following weight percentage ratio:
Process Radix Aconiti 3.92% Radix Aconiti Kusnezoffii Preparata 3.92% HUOXUETENG 5.88%
Radix Angelicae Sinensis 5.88% Typhonium flagelliforme (Lodd.) Blume 5.88% Radix Achyranthis Bidentatae 5.88%
Herba Taxilli 9.80% Radix Clematidis 9.80% Rhizoma Corydalis 30.94%
Eupolyphaga Seu Steleophaga 5.88% Scorpio 5.88% Radix Angelicae Pubescentis 5.88%
Scolopendra 0.46%;
The preparation method of the Chinese medicine suppository of above-mentioned treatment prolapse of lumbar intervertebral disc: cleaned by above-mentioned medical material, drain, adds the edible ethanol of 95% of crude drug quality quintuple, extracts one hour, is concentrated into the extractum that proportion is 1.20 ~ 1.25 after filtration; Then with extractum mass ratio be the Polyethylene Glycol of 49.5 ℅, after the glycerol of the glyceryl monostearate of 49.5 ﹪ and 1.0 ℅ mixes with extractum, be heated to 50 DEG C ~ 55 DEG C, melt stir after, fill in suppository shell bag forming, under being stored in 5 DEG C ~ 28 DEG C temperature environments.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410292138.3A CN104013687B (en) | 2014-06-26 | 2014-06-26 | A kind of Chinese medicine suppository for the treatment of prolapse of lumbar intervertebral disc |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410292138.3A CN104013687B (en) | 2014-06-26 | 2014-06-26 | A kind of Chinese medicine suppository for the treatment of prolapse of lumbar intervertebral disc |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104013687A CN104013687A (en) | 2014-09-03 |
| CN104013687B true CN104013687B (en) | 2015-11-04 |
Family
ID=51430870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410292138.3A Active CN104013687B (en) | 2014-06-26 | 2014-06-26 | A kind of Chinese medicine suppository for the treatment of prolapse of lumbar intervertebral disc |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104013687B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106821956A (en) * | 2017-02-21 | 2017-06-13 | 徐伟 | A kind of leech source antithrombin activity material suppository |
| CN112569276A (en) * | 2019-09-30 | 2021-03-30 | 熊亚非 | Traditional Chinese medicine composition formula for treating lumbar disc herniation and spinal stenosis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1895600A (en) * | 2006-06-15 | 2007-01-17 | 方焕生 | Chinese-medicinal suppository for treating lumbar vertebrae disease |
-
2014
- 2014-06-26 CN CN201410292138.3A patent/CN104013687B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1895600A (en) * | 2006-06-15 | 2007-01-17 | 方焕生 | Chinese-medicinal suppository for treating lumbar vertebrae disease |
Non-Patent Citations (2)
| Title |
|---|
| 中医药治疗腰椎间盘突出症的研究近况;郑晓红;<<上海中医药杂志>>;20010731(第7期);47-49 * |
| 中药内治腰椎间盘突出症研究进展;林雪娟等;<<中国中药杂志>>;20070228;第32卷(第3期);186-191 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104013687A (en) | 2014-09-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1803187A (en) | Chinese herbal medicine for treating lumbar intervertebral disk protrusion and hyperosteogeny | |
| CN102920876B (en) | External-application Chinese medicinal composition for treating knee osteoarthritis | |
| CN103191382B (en) | Medicine for treating Bi syndrome and preparation method thereof | |
| CN101507802A (en) | Medicine for treating ankylosing spondylitis | |
| CN103893380A (en) | Traditional Chinese medicinal preparation for treating vertebral hyperosteogeny | |
| CN104013687B (en) | A kind of Chinese medicine suppository for the treatment of prolapse of lumbar intervertebral disc | |
| CN103028067B (en) | Traditional Chinese medicine composition for treating renal cyst | |
| CN104000993A (en) | Pills with effects of strengthening bones and stretching muscles and tendons and preparation technology thereof | |
| CN103751481B (en) | One treats talalgia Chinese medicine for oral administration | |
| CN103316296B (en) | Traditional Chinese medicine composition for treating hyperostosis | |
| CN105434972A (en) | Traditional Chinese medicine composition for treating breast hyperplasia | |
| CN102600272B (en) | Traditional Chinese medicine for treatment of orthopedic disease | |
| CN104587252A (en) | Traditional Chinese medicine composition for treating kidney stones | |
| CN104189357A (en) | Traditional Chinese medicine ointment for treating rheumatoid arthritis | |
| CN103127458A (en) | Drug for treating osteoarticular myalgia | |
| CN103705864B (en) | A kind of steaming bone hot compress plaster for the treatment of cervical vertebra, lumbar spondylosis | |
| CN103585483B (en) | Traditional Chinese medicine composition for treating knee osteoarthritis and preparation method of same | |
| CN104173689A (en) | Medicine for treating traumatic injury, lumbar disc herniation and scapulohumeral periarthritis and preparation method of medicine | |
| CN104606313A (en) | Traditional Chinese medicinal ointment for treating osteoarticular diseases and bone fractures | |
| CN103585273A (en) | Traditional Chinese medicine composition for treating local swelling and pain | |
| CN103191305A (en) | Traditional Chinese medicine composition for treating hyperosteogeny | |
| CN103223012B (en) | External traditional Chinese medicine composition for treating sudden sprain in lumbar region and acute chest pain and preparation method thereof | |
| CN102600251A (en) | Compound rheumatism-rehabilitating composite agent | |
| CN103285108B (en) | Chinese medicinal composition treating lumbago | |
| CN102430066B (en) | Sciatic nerve liquid |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20160429 Address after: 438000 No. 170, Huangzhou Avenue, Huanggang, Hubei Patentee after: Huanggang Weierkang Pharmaceutical Co., Ltd. Address before: 802 room 3, unit 9, building 434300, Gongan County people's Hospital, Hubei, Jingzhou Patentee before: Xu Wei Patentee before: Xu Xiaopu |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20211123 Address after: 438000 qingzhuanhu Road, Xihu Industrial Park, Huanggang City, Hubei Province Patentee after: HUBEI WEIERKANG MODERN TRADITIONAL CHINESE MEDICINE CO.,LTD. Address before: 438000 No. 170, Huangzhou Avenue, Huanggang City, Hubei Province Patentee before: Huanggang Weierkang Pharmaceutical Co.,Ltd. |