CN102908464A - Radix tetrastigme micro powder and preparation method and application thereof - Google Patents
Radix tetrastigme micro powder and preparation method and application thereof Download PDFInfo
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- CN102908464A CN102908464A CN2012104224784A CN201210422478A CN102908464A CN 102908464 A CN102908464 A CN 102908464A CN 2012104224784 A CN2012104224784 A CN 2012104224784A CN 201210422478 A CN201210422478 A CN 201210422478A CN 102908464 A CN102908464 A CN 102908464A
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- lespedezae buergeri
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Abstract
The invention relates to a radix tetrastigme extracting preparation method, in particular to radix tetrastigme micro powder and a preparation method and application thereof. The preparation method of the radix tetrastigme micro powder includes the steps: 1) cleaning, by weight, 60%-90% of radix tetrastigme leaves, 8%-35% of aerial stems and 0.5%-5% of radix tetrastigme flowers by clear water prior to centrifugal dewatering; 2) adding filtered and disinfected clear water accounting for 5%-20% of the total weight of the raw materials, grinding, crushing, passing through 150-200 meshes, and centrifugally removing tissue fibers in slurry; 3) performing solution spray drying for the centrifuged radix tetrastigme slurry, and performing atomization drying at the temperature of 90-95 DEG C so that radix tetrastigme powder is obtained; and 4) performing vacuum packaging for the radix tetrastigme powder for standby. The radix tetrastigme extracting preparation method has the advantages of simple technological production process, high pharmaceutical effect and high effective component retention.
Description
Technical field
The present invention relates to a kind of extraction preparation method of Radix Apioris Fortunei (Radix Lespedezae Buergeri), relate in particular to a kind of Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder and its preparation method and application.
Background technology
Radix Apioris Fortunei (Radix Lespedezae Buergeri) (Tetrastigma hemsleyanum Diels et Gilg) is vitaceae, has another name called gold thread hoist, SANYE Caulis et Radix Tetrastigmatis Planicaulis, stone mouse, little Caulis et Radix Tetrastigmatis Planicaulis, stone monkey, soil through ball, SANYE pair.The main place of production in Southwestern China section and Anhui, Zhejiang, Jiangxi, Fujian, Hubei, Hunan, Guangdong, Guangxi.
Radix Apioris Fortunei (Radix Lespedezae Buergeri) is with tuber and all herbal medicine, and Radix Apioris Fortunei (Radix Lespedezae Buergeri) has magical medicinal effects, has the immunity of raising, antiviral, enhancing liver function, is usually used in clinically treating hyperpyrexia convulsion, and rheumatism is ached, menoxenia, cough with asthma purulent sputum, pharyngalgia scrofula, the diseases such as carbuncle furuncle.To pneumonia, tuberculous lymphadenitis, hepatitis, the severe infections diseases such as gastritis, cervicitis, septicemia have obvious curative effects.The diseases such as Several Kinds of Malignancy and hypertension, heart disease, diabetes, neurasthenia all had extensive and good therapeutical effect.
Modern medicine study shows: Radix Apioris Fortunei (Radix Lespedezae Buergeri) all has good therapeutical effect to the overwhelming majority's primary carcinoma, metastatic carcinoma etc., all untoward reaction that chemotherapy of tumors is brought,, vomiting low such as appetite, feel sick, alopecia and leukopenia etc. all improve significantly, patients with terminal is had the alleviating pain effect, and it can also improve the immunologic function of human body effectively; And Radix Apioris Fortunei (Radix Lespedezae Buergeri) tool wide spectrum (applicable various solid tumors and non-patients with solid tumor are taken), efficiently (can improve rapidly cancer fever, pain, ascites pleural fluid, leukopenia, anorexia, the cachexia symptom such as weak, rapid-action, clinical total effective rate is high), nontoxic (is pure natural plant extract, without any side effects through testing), have no drug resistance (can be comprehensive, the inhibition tumor of too many levels, many target spots, fully different from the cytotoxicity of chemotherapeutics, clinical application does not have the drug resistance situation to occur).
Chinese invention patent (application number: 200810120750.7 applyings date: 2008-09-11) disclose a kind of from Radix Apioris Fortunei (Radix Lespedezae Buergeri) the technique of high efficiency extraction flavone compound.Its technological process is: the raw material Radix Apioris Fortunei (Radix Lespedezae Buergeri), air-dry, chopping adds entry and extracts in ultrasonic extractor, and extracting solution is concentrated into certain volume, carries out adsorption bleaching with active carbon again.Then utilize cavitation suspension extraction segregation apparatus, use first ethyl acetate extraction, reclaim ethyl acetate, aqueous solution is partly used chloroform extraction, reclaim chloroform, the aqueous solution partial concentration is extremely distinguished the flavor of without organic reagent, by macroporous adsorbent resin, water and 50% ethanol elution are collected 50% ethanol elution successively, reclaim solvent to doing, namely obtain the Radix Apioris Fortunei (Radix Lespedezae Buergeri) extract.
At present, the Radix Apioris Fortunei (Radix Lespedezae Buergeri) plantation generally needs could gather in the crops more than 4 years at least, and the exploitation of Radix Apioris Fortunei (Radix Lespedezae Buergeri) product mainly concentrates on underground medicinal rhizome part, a large amount of SANYE Folium Isatidis, the exploitation of stem on the ground after how the Cultivate administration phase in 4 years increases grower's income and excavate.Research finds, SANYE Folium Isatidis, stem, spends and has equally good medicinal efficacy, contains abundant Tetrastigma hemsleyanum Diels et Gilg flavone, gallic acid, kaempferol composition, and just pharmaceutical ingredient content is about about 70% of underground medicinal part.But almost 100% SANYE Folium Isatidis, stem, flower etc. all are discarded on planting base or the mountain, do not utilize, and cause the great wasting of resources.
Summary of the invention
For the SANYE Folium Isatidis is carried out deep processing and polish, turn waste into wealth, exploitation SANYE Folium Isatidis resource is increased farmers' income and is satisfied consumers in general's demand.First purpose of the present invention provides a kind of Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder, and second purpose of the present invention provides the preparation method of above-mentioned Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder, and the 3rd purpose of the present invention provides the application of above-mentioned Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder.The present invention is a kind of product take the SANYE Folium Isatidis as main component, contain the composition products such as abundant Tetrastigma hemsleyanum Diels et Gilg flavone, gallic acid, kaempferol, has the establishment tumor cell proliferation, promote apoptosis of tumor cells, the antitumor action that tool is good, and nontoxic secondary the work are easy to absorb, good for health, can be used as the raw material of multiple product.
In order to realize first above-mentioned purpose, the present invention has adopted following technical scheme:
The Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder, the preparation method of this Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder comprises following step:
1) raw material is according to weight ratio Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade 60% ~ 90%, the aerial stem of plant 8% ~ 35%, blue and white 0.5% ~ 5% ratio of SANYE, with Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade, the aerial stem of plant, flower, with clear water clean, after the centrifuge dehydration;
2) add 5% ~ 20% the clear water that accounts for the above-mentioned raw materials gross weight through filtering, disinfecting, polishing is broken, crosses the 150-200 order, the tissue fibers in the centrifugal removal serosity again;
3) with the Radix Apioris Fortunei (Radix Lespedezae Buergeri) serosity after centrifugal, carry out the solution spray drying, atomization drying under 90-95 ℃ of temperature gets the SANYE Calomelas;
4) the SANYE Calomelas is carried out vacuum packaging, stand-by.
As preferably, above-mentioned step 1) Raw is Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade 70% ~ 80%, the aerial stem of plant 18% ~ 29%, SANYE blue and white 1% ~ 3%.
In order to realize second above-mentioned purpose, the present invention has adopted following technical scheme:
The preparation method of Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder, this preparation method comprises following step:
1) raw material is according to weight ratio Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade 60% ~ 90%, the aerial stem of plant 8% ~ 35%, blue and white 0.5% ~ 5% ratio of SANYE, with Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade, the aerial stem of plant, flower, with clear water clean, after the centrifuge dehydration;
2) add 5% ~ 20% the clear water that accounts for the above-mentioned raw materials gross weight through filtering, disinfecting, polishing is broken, crosses the 150-200 order, the tissue fibers in the centrifugal removal serosity again;
3) with the Radix Apioris Fortunei (Radix Lespedezae Buergeri) serosity after centrifugal, carry out the solution spray drying, atomization drying under 90-95 ℃ of temperature gets the SANYE Calomelas;
4) the SANYE Calomelas is carried out vacuum packaging, stand-by.
As preferably, above-mentioned step 1) Raw is Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade 70% ~ 80%, the aerial stem of plant 18% ~ 29%, SANYE blue and white 1% ~ 3%.
As preferably, above-mentioned step 2) in the addition of clear water be the Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade gross weight 8% ~ 12%.
In order to realize the 3rd above-mentioned purpose, the present invention has adopted following technical scheme:
The fabricated product of Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder, this fabricated product can be instant tea, buccal tablet, food additive, health product or medicine.
The present invention is owing to having adopted above-mentioned technical scheme, this explained hereafter operation is simple, drug effect is high, effective ingredient keeps high, the Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder that makes is a kind of product take the SANYE Folium Isatidis as main component, contains the composition products such as abundant Tetrastigma hemsleyanum Diels et Gilg flavone, gallic acid, kaempferol, has the establishment tumor cell proliferation, promote apoptosis of tumor cells, the antitumor action that tool is good, and nontoxic secondary the work are easy to absorb, good for health, can be used as the raw material of multiple product.
The specific embodiment
Below in conjunction with the specific embodiment of the present invention is made a detailed explanation.
The Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder, the preparation method of this Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder comprises following step:
1) pluck cleaning: all can pluck the whole year, the fresh blade of Radix Apioris Fortunei (Radix Lespedezae Buergeri), stem, flower are picked, according to weight ratio Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade (70% ~ 80%), stem (29% ~ 18%), SANYE blue and white (1% ~ 2%) ratio proportioning, then with filter, disinfected spring water with Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade, rattan, take dust, earth is rinsed well, then centrifuge dehydration;
2) polishing is broken: in the raw materials such as the SANYE Folium Isatidis that passes through cleaning, stem, flower, add the spring water that accounts for the gross weight 10%-12% such as SANYE Folium Isatidis, rattan, flower through filtering, disinfecting, the fragmentation of polishing, rear to cross the 150-200 mesh filter screen centrifugal, filters the tissue fibers of removing wherein;
3) with Radix Apioris Fortunei (Radix Lespedezae Buergeri) serosity centrifugal, after filtering, carry out the solution spray drying, the atomization drying temperature is controlled at 90-95 ℃, final SANYE Calomelas;
4) dried SANYE Calomelas is carried out vacuum packaging, stand-by.
The above-mentioned Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder that makes can be used as various Radix Apioris Fortunei (Radix Lespedezae Buergeri) processed goods (instant tea, buccal tablet, food additive, health product, medicine etc.) main raw material(s).
Claims (6)
1. Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder is characterized in that the preparation method of this Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder comprises following step:
1) raw material is according to weight ratio Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade 60% ~ 90%, the aerial stem of plant 8% ~ 35%, blue and white 0.5% ~ 5% ratio of SANYE, with Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade, the aerial stem of plant, flower, with clear water clean, after the centrifuge dehydration;
2) add 5% ~ 20% the clear water that accounts for the above-mentioned raw materials gross weight through filtering, disinfecting, polishing is broken, crosses the 150-200 order, the tissue fibers in the centrifugal removal serosity again;
3) with the Radix Apioris Fortunei (Radix Lespedezae Buergeri) serosity after centrifugal, carry out the solution spray drying, atomization drying under 90-95 ℃ of temperature gets the SANYE Calomelas;
4) the SANYE Calomelas is carried out vacuum packaging, stand-by.
2. Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder according to claim 1 is characterized in that the step 1) Raw is Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade 70% ~ 80%, the aerial stem of plant 18% ~ 29%, SANYE blue and white 1% ~ 3%.
3. the preparation method of Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder is characterized in that this preparation method comprises following step:
1) raw material is according to weight ratio Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade 60% ~ 90%, the aerial stem of plant 8% ~ 35%, blue and white 0.5% ~ 5% ratio of SANYE, with Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade, the aerial stem of plant, flower, with clear water clean, after the centrifuge dehydration;
2) add 5% ~ 20% the clear water that accounts for the above-mentioned raw materials gross weight through filtering, disinfecting, polishing is broken, crosses the 150-200 order, the tissue fibers in the centrifugal removal serosity again;
3) with the Radix Apioris Fortunei (Radix Lespedezae Buergeri) serosity after centrifugal, carry out the solution spray drying, atomization drying under 90-95 ℃ of temperature gets the SANYE Calomelas;
4) the SANYE Calomelas is carried out vacuum packaging, stand-by.
4. the preparation method of Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder according to claim 1 is characterized in that the step 1) Raw is Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade 70% ~ 80%, the aerial stem of plant 18% ~ 29%, SANYE blue and white 1% ~ 3%.
5. the preparation method of Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowder according to claim 1 is characterized in that step 2) in the addition of clear water be the Radix Apioris Fortunei (Radix Lespedezae Buergeri) blade gross weight 8% ~ 12%.
6. adopt the fabricated product of claim 1 or 2 described Radix Apioris Fortunei (Radix Lespedezae Buergeri) micropowders, it is characterized in that: this fabricated product is instant tea, buccal tablet, food additive, health product or medicine.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103127314A (en) * | 2013-02-25 | 2013-06-05 | 胡馨尹 | Hemsley rockvine root tuber used for treating cancer fever |
| CN103169815A (en) * | 2013-04-09 | 2013-06-26 | 丽水市莲都区绿谷三叶青珍稀植物研究所 | Radix tetrastigme lozenge and preparation method thereof |
| CN103623036A (en) * | 2013-09-13 | 2014-03-12 | 浙江中医药大学中药饮片有限公司 | Radix tetrastigme direct oral herbal medicine and preparation method thereof |
| CN104431199A (en) * | 2014-12-22 | 2015-03-25 | 吴绍平 | Health radix tetrastigme tea and preparation method thereof |
| CN106072529A (en) * | 2016-06-18 | 2016-11-09 | 程龙凤 | A kind of processing method of Cerasus humilis Bunge Radix Apioris Fortunei (Radix Lespedezae Buergeri) nutrient tablet |
| CN109303819A (en) * | 2018-11-24 | 2019-02-05 | 郎国忠 | A kind of processing technology of radix tetrastigme |
| CN109566809A (en) * | 2018-12-24 | 2019-04-05 | 宁波市昱博药业有限公司 | A kind of preparation method of radix tetrastigme nutrition and health care jasmine tea |
| CN114470073A (en) * | 2022-03-15 | 2022-05-13 | 朱建国 | Radix tetrastigme fried carbon powder agent for treating digestive tract ulcer |
| CN114569660A (en) * | 2022-03-21 | 2022-06-03 | 朱建国 | Radix tetrastigme spray for resisting bacteria and diminishing inflammation |
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| CN1164961A (en) * | 1996-05-11 | 1997-11-19 | 鲁兴福 | Finely ground tea powder paste and its use |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103127314A (en) * | 2013-02-25 | 2013-06-05 | 胡馨尹 | Hemsley rockvine root tuber used for treating cancer fever |
| CN103169815A (en) * | 2013-04-09 | 2013-06-26 | 丽水市莲都区绿谷三叶青珍稀植物研究所 | Radix tetrastigme lozenge and preparation method thereof |
| CN103623036A (en) * | 2013-09-13 | 2014-03-12 | 浙江中医药大学中药饮片有限公司 | Radix tetrastigme direct oral herbal medicine and preparation method thereof |
| CN103623036B (en) * | 2013-09-13 | 2016-02-17 | 浙江中医药大学中药饮片有限公司 | Radix tetrastigme direct oral herbal medicine and preparation method thereof |
| CN104431199A (en) * | 2014-12-22 | 2015-03-25 | 吴绍平 | Health radix tetrastigme tea and preparation method thereof |
| CN106072529A (en) * | 2016-06-18 | 2016-11-09 | 程龙凤 | A kind of processing method of Cerasus humilis Bunge Radix Apioris Fortunei (Radix Lespedezae Buergeri) nutrient tablet |
| CN109303819A (en) * | 2018-11-24 | 2019-02-05 | 郎国忠 | A kind of processing technology of radix tetrastigme |
| CN109566809A (en) * | 2018-12-24 | 2019-04-05 | 宁波市昱博药业有限公司 | A kind of preparation method of radix tetrastigme nutrition and health care jasmine tea |
| CN114470073A (en) * | 2022-03-15 | 2022-05-13 | 朱建国 | Radix tetrastigme fried carbon powder agent for treating digestive tract ulcer |
| CN114569660A (en) * | 2022-03-21 | 2022-06-03 | 朱建国 | Radix tetrastigme spray for resisting bacteria and diminishing inflammation |
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| CN102908464B (en) | 2016-05-25 |
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Effective date of registration: 20210916 Address after: 323000 workshop 2, floor 2, block B, building 1, No. 268, Shiniu Road, nanmingshan street, Liandu District, Lishui City, Zhejiang Province Patentee after: Zhejiang Zhongxing Biomedical Technology Co.,Ltd. Address before: 323000 no.827, Liyang street, Liandu District, Lishui City, Zhejiang Province Patentee before: LISHUI LIANDU LVGU SANYEQING RARE PLANT INSTITUTE |