CN102886006B - Medicinal lotion for treating female vaginal discharge diseases and preparation method thereof - Google Patents

Medicinal lotion for treating female vaginal discharge diseases and preparation method thereof Download PDF

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CN102886006B
CN102886006B CN201210357058.2A CN201210357058A CN102886006B CN 102886006 B CN102886006 B CN 102886006B CN 201210357058 A CN201210357058 A CN 201210357058A CN 102886006 B CN102886006 B CN 102886006B
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radix
lotion
cortex
root
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CN102886006A (en
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孙凤霞
张宗保
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Abstract

The invention relates to a medicinal lotion for treating female vaginal discharge diseases and a preparation method thereof. The medicinal lotion is prepared from the following Chinese medicinal bulk pharmaceuticals in parts by weight: 16-22 parts of paris rhizome, 18-24 parts of selinum japenious seed, 12-18 parts of pepper, 2-6 parts of menthol, 10-16 parts of jasmine, 3-9 parts of gorgon euryale seed, 3-7 parts of tuber fleeceflower root, 4-10 parts of areca nut, 18-26 parts of virgate wormwood herb, 15-21 parts of lightyellow sophora root, 6-10 parts of double-teeth pubescent angelica root, 13-19 parts of sessile stemona root, 8-12 parts of figwort, 13-19 parts of honeysuckle flower, 12-18 parts of belvedere fruit, 6-10 parts of cortex dictamni, 14-20 parts of golden larch bark, 11-17 parts of baikal skullcap root, 6-12 parts of red paeony root, 11-17 parts of Chinese mugwort leaf, 9-13 parts of grassleaf sweelflag rhizome, 10-16 parts of amur corktree bark and 10-18 parts of Chinese atractylodes. The medicinal lotion is used for treating female vaginal discharge diseases, is convenient to use, has a definite curative effect, and is free from remarkable toxic and side effects.

Description

A kind of lotion of medication and preparation method for the treatment of vaginal discharge diseases of women
Technical field
The invention belongs to medical technical field, be specifically related to a kind of lotion of medication and preparation method for the treatment of vaginal discharge diseases of women of pure Chinese medicine.
Background technology
Leukorrheal diseases refer to leukorrhagia amount showed increased, and color, matter, abnormal smells from the patient are abnormal, or with whole body or local symptom, are commonly encountered disease, frequently-occurring disease; Cause the reason of leukorrheal diseases a lot, as trichomonal vaginitis, colpitis mycotica, senile vaginitis, cervical erosion, cervical polyp, endometritis, cervical cancer etc.; The common leucorrhoea grow in quantity of leukorrheal diseases clinical manifestation, continuous constantly, lumbago, Mental fatigue etc., or see and redly hold concurrently mutually in vain, or the five colors assorted under, or the turbid sample of pus, has foul smell; If rancid unpleasant, whether there is canceration when watching out for.The western medicine cause of disease is thought, in the time that Abwehrkraft des Koepers declines or ignores vulvovaginal health, pathogenic microorganism is driven in the wrong direction and is invaded vagina by vagina collar extension, destroy the natural defensive enginery of vagina, cause various vaginitiss, mainly comprise " nonspecific vaginitis ", " colpitis mycotica ", " trichomonal vaginitis " etc., its clinical symptoms is equivalent to the leukorrheal diseases of Chinese medicine.
Patent 200510105327.6 discloses a kind of Lifukang medicine for vagina and preparation method thereof, this medicine is by Chinese crude drugs such as the Radix Sophorae Flavescentis of constant weight proportioning, Cortex Phellodendri, Fructus Cnidii, Cortex Dictamni, Rhizoma Coptidis, Pericarpium Zanthoxyli, the Fructus Kochiae, Radix Isatidis, Radix Paeoniae Rubra, Radix Polygoni Multiflori, Rhizoma Smilacis Glabraes, make preparation by certain process, especially vagina medicinal, as suppository, lotion, gel, vagina effervescence agent, this medicine is for various colpitis such as the leukorrhagia due to damp-heat accumulation, pudendal pruritus, vulvitises.But this medicine to spleen deficiency of kidney-QI can not removing dampness, the turbid damp bet leukorrheal diseases effect that causes appointing belt restraining function mistake department to form is not ideal enough.
Patent 200810138135.9 discloses one and has treated pruritus vulvae, the lotion of leucorrhea with red and white discharge, this lotion is by the pharmacodynamic raw materials of following weight proportioning: Radix Sophorae Flavescentis 40-80 gram, Fructus Cnidii 30-60 gram, Cortex Phellodendri 20-40 gram, Cortex Dictamni 10-40 gram, Fructus Kochiae 20-50 gram, Pericarpium Zanthoxyli 10-30 gram, Herba Taraxaci 40-80 gram is ground into coarse powder, infiltrate in right amount 3 hours with ethanol-glacial acetic acid (3:1) mixed solution, pack in percolation bucket, add above-mentioned mixed solution dipping 48 hours, with the speed percolation of 1-3ml per minute, collect percolate, following concentrated at 60 DEG C, add Alumen 10-40 gram, leave standstill, filter, be adjusted into 1000ml.This lotion has heat-clearing and toxic substances removing, and the effect of killing parasites for relieving itching has obvious curative effects to treatment pruritus vulvae, leucorrhea with red and white discharge, and the form of lotion is easy to use, with low cost, economical and practical, can alleviate patient economy burden.But this lotion is same mainly by the eliminating evil ingredients of heat clearing and damp drying, can not removing dampness to spleen deficiency of kidney-QI, the leukorrheal diseases effect that turbid damp bet causes appointing belt restraining function mistake department to form is not ideal enough equally.
In view of this, the inventor has developed a kind of easy to use, determined curative effect and the pure Chinese medicinal preparation without obvious toxic-side effects, to meet the demand of extensive patients.
Summary of the invention
The object of this invention is to provide a kind of easy to use, determined curative effect and the pure Chinese medicinal preparation without obvious toxic-side effects.
The present invention for achieving the above object, is achieved through the following technical solutions:
A kind of lotion of medication for the treatment of vaginal discharge diseases of women, be prepared from by the raw material of Chinese medicine medicine of following weight proportion: Rhizoma Paridis 16-22 part, Fructus Cnidii 18-24 part, Pericarpium Zanthoxyli 12-18 part, Mentholum 2-6 part, Fructus Gardeniae 10-16 part, Semen Euryales 3-9 part, Radix Polygoni Multiflori 3-7 part, Semen Arecae 4-10 part, Herba Artemisiae Scopariae 18-26 part, Radix Sophorae Flavescentis 15-21 part, Radix Angelicae Pubescentis 6-10 part, Radix Stemonae 13-19 part, Radix Scrophulariae 8-12 part, Flos Lonicerae 13-19 part, Fructus Kochiae 12-18 part, Cortex Dictamni 6-10 part, Cortex Pseudolaricis 14-20 part, Radix Scutellariae 11-17 part, Radix Paeoniae Rubra 6-12 part, Folium Artemisiae Argyi 11-17 part, Rhizoma Acori Graminei 9-13 part, Cortex Phellodendri 10-16 part, Rhizoma Atractylodis 10-18 part.Weight proportion is preferably: 19 parts of Rhizoma Paridis, 21 parts of Fructus Cnidiis, 15 parts, Pericarpium Zanthoxyli, 4 parts of Mentholums, 13 parts of Fructus Gardeniaes, 6 parts of Semen Euryaless, 5 parts of Radix Polygoni Multiflori, 7 parts of Semen Arecaes, 22 parts of Herba Artemisiae Scopariaes, 18 parts of Radix Sophorae Flavescentiss, 8 parts of Radix Angelicae Pubescentiss, 16 parts of the Radixs Stemonae, 10 parts of Radix Scrophulariaes, 16 parts of Flos Loniceraes, 15 parts of the Fructus Kochiae, 8 parts of Cortex Dictamni, 17 parts of Cortex Pseudolariciss, 14 parts of Radix Scutellariaes, 9 parts of Radix Paeoniae Rubra, 14 parts of Folium Artemisiae Argyis, 11 parts of Rhizoma Acori Graminei, 13 parts of Cortex Phellodendris, 14 parts of Rhizoma Atractylodis.
This lotion of medication preparation method, comprises the steps:
A) take various raw materials according to required weight portion;
B) Mentholum is ground into fine powder, sieves for subsequent use;
C), by Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi, Rhizoma Atractylodis water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
D) medicinal residues after all the other 17 taste components and above-mentioned distillating extracting oil, decoct with water extraction secondary, add for the first time 5 times of water gagings of injection volume and decoct 2 hours, adding for the second time 4 times of water gagings of injection volume decocts 1.0 hours, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; It is 1.11~1.14 concentrated solution that 60 DEG C of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 70% containing alcohol amount, stirs evenly, and leaves standstill cold preservation (2~5 DEG C) 24 hours, filters; Filtrate recycling ethanol to be concentrated into relative density be 1.10~1.12 (60 DEG C), adds the water dilution of equivalent, stirs evenly, then leaves standstill cold preservation (2~5 DEG C) 24 hours, filters;
E) filtrate adds above-mentioned Mentholum fine powder, with adding with stirring; And regulate pH value to 4.5~6.0, and add water and be adjusted to 1000ml, filter, sterilizing, to obtain final product.
The usage and dosage of lotion of medication of the present invention is: with lotion of medication of the present invention (get this product 20ml and add warm water to 200ml, mix) the scouring pudendum of 10% concentration; Or the lotion of medication of the present invention of 10% concentration is delivered to vagina deep washing vagina with irrigator.2 times on the one 8 days is a course for the treatment of.
Band purgation name is for " empty talk of Plain Questions bone " " conception vessel is disease, ties seven kinds of hernia in man, and woman's leukorrhagia abdominal mass is poly-".Chinese medicine is thought: traditional Chinese medical science disease leukorrheal diseases refer to woman vagina secretions showed increased, color, matter, the abnormal symptom of abnormal smells from the patient; Leukorrheal diseases are many because of damp and hot, noxious dampness, or insufficiency of the spleen, suffer from a deficiency of the kidney etc. due to, cold-damp or damp invasion of lower energizer, or pyretic toxicity contamination, or the Chang Kejian leukorrhagia such as spleen kidney yang gas virtual loss is abnormal; Leukorrhagia generally sees the evil poison of cysthus local infection, or the pathological changes of uterus etc., is most commonly in leukorrheal diseases.
How the touching difficulty of leukorrheal diseases more, is not coexisted by cold-damp and damp and hot heterogeneous, the dai channel of suffering from a deficiency of the kidney admittedly, and treatment should reinforcing spleen and kidney, heat clearing and damp drying, killing parasites for relieving itching.Fang Zhongyong Rhizoma Paridis, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Stemonae heat clearing and damp drying, killing parasites for relieving itching are monarch drug in side; With Fructus Gardeniae, Radix Scutellariae, Cortex Phellodendri, Herba Artemisiae Scopariae, Flos Lonicerae, Cortex Dictamni, the Fructus Kochiae, Cortex Pseudolaricis heat clearing and damp drying, dispel damp and hotly, Pericarpium Zanthoxyli, Folium Artemisiae Argyi, Radix Angelicae Pubescentis are dispelled cold-damp, Radix Scrophulariae, Radix Paeoniae Rubra clearing away heat and cooling blood, Semen Euryales, Radix Polygoni Multiflori invigorating kidney, promoting blood circulation, be ministerial drug in side altogether; Rhizoma Acori Graminei, Semen Arecae are tying-in medicine, have effect of heat-clearing and toxic substances removing, eliminating dampness and arresting leucorrhea simultaneously, are adjuvant drug in side altogether; With Mentholum, for making medicine, Mentholum is fragrant carminative, makes skin or mucosa produce refrigerant sense to alleviate discomfort and pain with it.Full side coordinates, and gathers altogether the merit of heat clearing and damp drying, killing parasites for relieving itching, the leukorrheal diseases that the touching difficulty due to the damp-heat accumulation of holding concurrently for suffering from a deficiency of the kidney heals.
With the passing of time lotion of medication of the present invention is particularly useful for the course of disease, the patient of outbreak repeatedly, and curative effect is better more outstanding.
For showing the curative effect of lotion of medication of the present invention, spy provides clinical typical case history:
Wang, female, 72 years old, on July 24th, 2011 was medical.Patient's private prosecution leucorrhea is had a surplus foul half a year, once several institutes hospital attached to a medical college diagnosis and treatment in locality, through ultrasound diagnosis: uterine hydrops, have no space occupying lesion, uterus, cervical scraping smear do not find cancerous cell.After the quiet therapeutic effect of medicine such as penicillin, ofloxacin, ceftriaxone sodium are not good enough, take orally and do not take effect yet with 15 doses of Chinese Medicine Cortex Phellodendri, Rhizoma Atractylodis, Flos Lonicerae, Semen Plantaginis, Semen Ginkgo, Rhizoma Dioscoreae, Semen Euryales, Cortex Ailanthis etc., informal dress amoxicillin, norfloxacin, cefradine etc. produce little effect later, and still leukorrhagia is unbroken.Sign: profuse leukorrhea, every day, dripping urine endlessly, taking morning as many, like the non-water of water, like the non-pus of pus, like the non-blood of blood, foul unclear.With lotion of medication hip bath fumigation treatment of the present invention, every day 2 times, each 50mL, medication is cured for 2 weeks, follows up a case by regular visits to and does not recur half a year.
Remaining certain, female, 45 years old.First visit on November 3 in 2011.Patient's private prosecution is profuse leukorrhea yellow skin in this year, and its gas is smelly dirty, giddy, and vexed bitter taste, through Chinese and western medicine multi-treatment, has still time repeatedly, fails to effect a radical cure, agonizing.Be diagnosed as chronic pelvic inflammatory disease, vaginitis through many examination in hospital.Sign: band polychrome Huang, sticky, its gas is smelly dirty, pruritus vulvae, vexed bitter taste, giddy, lower abdominal distention pain connects and waist sacrum, sees its yellow fur and greasy, examines its stringy and rolling pulse and counts.With lotion of medication hip bath fumigation treatment of the present invention, every day 2 times, each 50mL, medication 1 week, leukorrhagia amount obviously reduces, if smelly dirty gas loses; Continue medication 2 weeks, all disease recoveries from illness.Follow up a case by regular visits to and have no recurrence half a year.
Liao, female, 43 years old, married, peasant.Within 2011, JIUYUE is examined on the 17th.Patient's private prosecution leucorrhea is had a surplus foul half a year, and profuse leukorrhea, matter is rare, taste is smelly, companion's bitter taste, vexed, insomnia, or pruritus vulvae, urine slightly yellow, body of the tongue is light red, yellow and thin fur.Gynaecological examination: pudendum is normal, vagina is unobstructed, and faint yellow secretions amount is medium, and cervix uteri is slightly rotten to the corn, position after the body of palace, normal size, bilateral adnexa is normal, and leucorrhea routine examination does not detect infusorian, mycete.Tcm diagnosis is leukorrheal diseases, and Western medicine diagnose is chronic cervicitis.With lotion of medication hip bath fumigation treatment of the present invention, every day 2 times, each 50mL, medication 1 week, leukorrhagia amount obviously reduces, if smelly dirty gas loses; Continue medication 2 weeks, all disease recoveries from illness.Follow up a case by regular visits to and have no recurrence half a year.
Above example is only representative case, has above curative effect person many in addition, no longer enumerates at this.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is further described, so that those skilled in the art more understands the present invention, but does not limit the present invention with this.
Embodiment 1
Prescription: Rhizoma Paridis 19g, Fructus Cnidii 21g, Pericarpium Zanthoxyli 15g, Mentholum 4g, Fructus Gardeniae 13g, Semen Euryales 6g, Radix Polygoni Multiflori 5g, Semen Arecae 7g, Herba Artemisiae Scopariae 22g, Radix Sophorae Flavescentis 18g, Radix Angelicae Pubescentis 8g, Radix Stemonae 16g, Radix Scrophulariae 10g, Flos Lonicerae 16g, Fructus Kochiae 15g, Cortex Dictamni 8g, Cortex Pseudolaricis 17g, Radix Scutellariae 14g, Radix Paeoniae Rubra 9g, Folium Artemisiae Argyi 14g, Rhizoma Acori Graminei 11g, Cortex Phellodendri 13g, Rhizoma Atractylodis 14g.
Method for making: a) take various raw materials according to required weight portion;
B) Mentholum is ground into fine powder, sieves for subsequent use;
C), by Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi, Rhizoma Atractylodis water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
D) medicinal residues after 17 tastes such as all the other Radix Sophorae Flavescentiss and above-mentioned distillating extracting oil, decoct with water extraction secondary, add for the first time 5 times of water gagings and decoct 2 hours, adding for the second time 4 times of water gagings decocts 1.0 hours, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; Filtrate is concentrated into the concentrated solution that relative density is 1.11~1.14 (60 DEG C), lets cool, and adds ethanol to reaching 70% containing alcohol amount, stirs evenly, and leaves standstill cold preservation (2~5 DEG C) 24 hours, filters; Filtrate recycling ethanol to be concentrated into relative density be 1.10~1.12 (60 DEG C), adds the water dilution of equivalent, stirs evenly, then leaves standstill cold preservation (2~5 DEG C) 24 hours, filters;
E) filtrate adds above-mentioned Mentholum fine powder, with adding with stirring; And regulate pH value to prescribed limit (4.5~6.0), and add water and be adjusted to 1000ml, filter, subpackage, sterilizing, to obtain final product.
Embodiment 2
Prescription: Rhizoma Paridis 22g, Fructus Cnidii 24g, Pericarpium Zanthoxyli 18g, Mentholum 6g, Fructus Gardeniae 16g, Semen Euryales 3g, Radix Polygoni Multiflori 3g, Semen Arecae 4g, Herba Artemisiae Scopariae 26g, Radix Sophorae Flavescentis 21g, Radix Angelicae Pubescentis 6g, Radix Stemonae 13g, Radix Scrophulariae 8g, Flos Lonicerae 19g, Fructus Kochiae 12g, Cortex Dictamni 6g, Cortex Pseudolaricis 14g, Radix Scutellariae 17g, Radix Paeoniae Rubra 6g, Folium Artemisiae Argyi 11g, Rhizoma Acori Graminei 13g, Cortex Phellodendri 16g, Rhizoma Atractylodis 10g.
Method for making: a) take various raw materials according to required weight portion;
B) Mentholum is ground into fine powder, sieves for subsequent use;
C), by Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi, Rhizoma Atractylodis water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
D) medicinal residues after 17 tastes such as all the other Radix Sophorae Flavescentiss and above-mentioned distillating extracting oil, decoct with water extraction secondary, add for the first time 5 times of water gagings and decoct 2 hours, adding for the second time 4 times of water gagings decocts 1.0 hours, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; 60 DEG C of filtrates are concentrated into the concentrated solution that relative density is 1.11~1.14 (), let cool, and add ethanol to reaching 70% containing alcohol amount, stir evenly, and 2~5 DEG C of standing cold preservation 24 hours, filters; It is 1.10~1.12 that filtrate recycling ethanol 60 DEG C are concentrated into relative density, adds the water dilution of equivalent, stirs evenly, then leaves standstill, and 2~5 DEG C of cold preservation 24 hours, filters;
E) filtrate adds above-mentioned Mentholum fine powder, with adding with stirring; And regulate pH value to 4.5~6.0, and add water and be adjusted to 1000ml, filter, subpackage, sterilizing, to obtain final product.
Embodiment 3
Prescription: Rhizoma Paridis 16g, Fructus Cnidii 18g, Pericarpium Zanthoxyli 12g, Mentholum 2g, Fructus Gardeniae 10g, Semen Euryales 9g, Radix Polygoni Multiflori 7g, Semen Arecae 10g, Herba Artemisiae Scopariae 18g, Radix Sophorae Flavescentis 15g, Radix Angelicae Pubescentis 10g, Radix Stemonae 19g, Radix Scrophulariae 12g, Flos Lonicerae 13g, Fructus Kochiae 18g, Cortex Dictamni 10g, Cortex Pseudolaricis 20g, Radix Scutellariae 11g, Radix Paeoniae Rubra 12g, Folium Artemisiae Argyi 17g, Rhizoma Acori Graminei 9g, Cortex Phellodendri 10g, Rhizoma Atractylodis 18g.
Method for making: a) take various raw materials according to required weight portion;
B) Mentholum is ground into fine powder, sieves for subsequent use;
C), by Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi, Rhizoma Atractylodis water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
D) medicinal residues after 17 tastes such as all the other Radix Sophorae Flavescentiss and above-mentioned distillating extracting oil, decoct with water extraction secondary, add for the first time 5 times of water gagings and decoct 2 hours, adding for the second time 4 times of water gagings decocts 1.0 hours, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; It is 1.11~1.14 concentrated solution that 60 DEG C of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 70% containing alcohol amount, stirs evenly, and 2~5 DEG C of standing cold preservation 24 hours, filters; It is 1.10~1.12 that filtrate recycling ethanol 60 DEG C are concentrated into relative density, adds the water dilution of equivalent, stirs evenly, then leaves standstill 2~5 DEG C of cold preservations 24 hours, filters;
E) filtrate adds above-mentioned Mentholum fine powder, with adding with stirring; And regulate pH value to 4.5~6.0, and add water and be adjusted to 1000ml, filter, subpackage, sterilizing, to obtain final product.
The preparation of embodiments of the invention l has been carried out to clinical pharmacodynamics test, and result is as follows:
Adopt washing liquid treatment vaginal discharge diseases of women of the present invention 132 examples, and compare with JIEERYIN XIYE.Result shows, in treatment group 132 examples, and clinical cure 105 examples, 24 examples that take a turn for the better, invalid 3 examples, all there is not toxicity in all cases; JIEERYIN XIYE matched group 72 examples, clinical cure 21 examples, 37 examples that take a turn for the better, invalid 14 examples.Result washing liquid treatment of the present invention vaginal discharge diseases of women total effective rate is 97.73%, the total effective rate of wherein treating chronic vaginal discharge diseases of women is 90.00%, and matched group is respectively 80.56%, 18.18%, treatment group is obviously better than JIEERYIN XIYE matched group, and learning by statistics processing difference has significant (P < 0.05).Point out washing liquid of the present invention all to have good curative effect to acute and chronic vaginal discharge diseases of women, and safe and reliable.

Claims (3)

1. treat the lotion of medication of vaginal discharge diseases of women for one kind, it is to be prepared from by the raw material of Chinese medicine medicine of following weight proportion: Rhizoma Paridis 16-22 part, Fructus Cnidii 18-24 part, Pericarpium Zanthoxyli 12-18 part, Mentholum 2-6 part, Fructus Gardeniae 10-16 part, Semen Euryales 3-9 part, Radix Polygoni Multiflori 3-7 part, Semen Arecae 4-10 part, Herba Artemisiae Scopariae 18-26 part, Radix Sophorae Flavescentis 15-21 part, Radix Angelicae Pubescentis 6-10 part, Radix Stemonae 13-19 part, Radix Scrophulariae 8-12 part, Flos Lonicerae 13-19 part, Fructus Kochiae 12-18 part, Cortex Dictamni 6-10 part, Cortex Pseudolaricis 14-20 part, Radix Scutellariae 11-17 part, Radix Paeoniae Rubra 6-12 part, Folium Artemisiae Argyi 11-17 part, Rhizoma Acori Graminei 9-13 part, Cortex Phellodendri 10-16 part, Rhizoma Atractylodis 10-18 part.
2. the lotion of medication for the treatment of vaginal discharge diseases of women according to claim 1, is prepared from by the raw material of Chinese medicine medicine of following weight proportion: 19 parts of Rhizoma Paridis, 21 parts of Fructus Cnidiis, 15 parts, Pericarpium Zanthoxyli, 4 parts of Mentholums, 13 parts of Fructus Gardeniaes, 6 parts of Semen Euryaless, 5 parts of Radix Polygoni Multiflori, 7 parts of Semen Arecaes, 22 parts of Herba Artemisiae Scopariaes, 18 parts of Radix Sophorae Flavescentiss, 8 parts of Radix Angelicae Pubescentiss, 16 parts of the Radixs Stemonae, 10 parts of Radix Scrophulariaes, 16 parts of Flos Loniceraes, 15 parts of the Fructus Kochiae, 8 parts of Cortex Dictamni, 17 parts of Cortex Pseudolariciss, 14 parts of Radix Scutellariaes, 9 parts of Radix Paeoniae Rubra, 14 parts of Folium Artemisiae Argyis, 11 parts of Rhizoma Acori Graminei, 13 parts of Cortex Phellodendris, 14 parts of Rhizoma Atractylodis.
3. the preparation method of the lotion of medication described in claim 1 or 2, comprises the steps:
(a) take various raw materials according to required weight portion;
(b) Mentholum is ground into fine powder, sieves for subsequent use;
(c), by Flos Lonicerae, Pericarpium Zanthoxyli, Herba Artemisiae Scopariae, Folium Artemisiae Argyi, Rhizoma Atractylodis water vapour distillation volatile oil, the another device of aqueous solution after distillation is collected;
(d) medicinal residues after all the other 17 taste components and above-mentioned distillating extracting oil, decoct with water extraction secondary, add for the first time 5 times of water gagings of injection volume and decoct 2 hours, adding for the second time 4 times of water gagings of injection volume decocts 1.0 hours, collecting decoction, then add the aqueous solution after above-mentioned distillation, filter; It is 1.11~1.14 concentrated solution that 60 DEG C of filtrates are concentrated into relative density, lets cool, and adds ethanol to reaching 70% containing alcohol amount, stirs evenly, and 2~5 DEG C of standing cold preservation 24 hours, filters; It is 1.10~1.12 that filtrate recycling ethanol 60 DEG C are concentrated into relative density, adds the water dilution of equivalent, stirs evenly, and 2~5 DEG C leave standstill cold preservation 24 hours again, filter;
(e) filtrate adds above-mentioned Mentholum fine powder, with adding with stirring; And regulate pH value to 4.5~6.0, and add water and be adjusted to 1000ml, filter, sterilizing, to obtain final product.
CN201210357058.2A 2012-09-24 2012-09-24 Medicinal lotion for treating female vaginal discharge diseases and preparation method thereof Expired - Fee Related CN102886006B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1565550A (en) * 2003-06-18 2005-01-19 薛永新 Chinese traditional medicine for treating gynecopathy and dermatoses and preparation thereof
CN1742938A (en) * 2005-09-23 2006-03-08 北京润德康医药技术有限公司 Lifukang medicine for vagina and preparing method thereof
CN101062205A (en) * 2006-04-26 2007-10-31 杨文龙 Chinese medicine composition for treating gynecopathy, the preparing method and the function

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