CN102885967A - Lozenge containing corsvenor momordica fruit and preparation method thereof - Google Patents
Lozenge containing corsvenor momordica fruit and preparation method thereof Download PDFInfo
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Abstract
The invention provides a lozenge containing corsvenor momordica fruit and a preparation method thereof. In the lozenge, a dry corsvenor momordica fruit extract is taken as a main raw material, and four types of dry Chinese medicinal extracts including honeysuckle flower, fringed iris, dwarf lilyturf root and chrysanthemum are added. The invention further provides a preparation method for the lozenge. The lozenge has the beneficial effects of easiness for process operation, remarkable product effect, the effects of expelling phlegm to arrest coughing, and moisten the throat, and particularly better effect on patients suffering from chronic pharyngitis.
Description
Technical field
The invention belongs to the Chinese medicine preparation technical field, especially relate to a kind of buccal tablet that contains Fructus Momordicae and preparation method thereof.
Background technology
In the market cleaning throat and moistening larynx to contain flake products many, such as watermelon crystal buccal tablet, Herba Pileae Scriptae Tabellae etc., buccal tablet people instant is easy to carry about with one.Chronic pharyngitis refers to the caused pathological changes of pharyngeal chronic infection, and the traditional Chinese medical science claims " globus hystericus ", is mainly in the adult, usually with other bottleneck throat symptoms, so on the books in the traditional Chinese medical science books: " the globus hystericus person has obstacles between throat; that coughs up does not go out, pharynx lower, and the shape person of nuclear is also." in the market also not for chronic pharyngitis and the little buccal tablet series products of side effect.Herba Pileae Scriptae Tabellae is usually used in the throat disease due to the affection due to external wind and heat, the acute pharyngolaryngitis of doctor trained in Western medicine indication namely, and the multiplex laryngopharynx swelling and pain that causes in " getting angry " of Waterelon Frost Lozenges.
Fructus Momordicae, Flos Lonicerae, Herba Iridis japonicae, Radix Ophiopogonis, Flos Chrysanthemi all are the Chinese herbal medicine commonly used that people are used for heat clearing away and internal heat reducing, and many people use Flos Chrysanthemi, Fructus Momordicae is soaked drinks cleaning throat and moistening larynx.Fructus Momordicae is a kind of rare medicinal herbs, sweet in the mouth cool in nature, function lung heat clearing intestine moistening.Cure mainly the diseases such as pertussis, phlegm-fire cough, the dry constipation of blood; For treatment acute tracheitis, acute tonsillitis, throat fire, acute gastritis good curative effect is arranged, smash to pieces with its root, spread on the affected part, can control stubborn dermatitis, carbuncle, furuncle etc.; Fruit Mao Kezuo drug for incised wound; With Fructus Momordicae a little, pour boiled water and soak, be a kind of fabulous refreshment drink, both can refresh oneself and promote the production of body fluid, but preventing respiratory tract infection again take throughout the year, can life lengthening.Arhat juice also can be used for the cooking, and delicate fragrance is good to eat, and Fructus Momordicae is described as " angle fruit " by people.
Flos Lonicerae is one of rare Chinese medicine commonly used.Have the effects such as heat-clearing and toxic substances removing, dredge the meridian passage, broad-spectrum antiseptic and antiviral, all contain Flos Lonicerae in the flu more than 70%, the antiinflammatory Chinese patent medicine.Have " Chinese medicine antibiotic ", " title of antibacterial green element.The effect of Flos Lonicerae is except medicinal, and its beauty treatment, fat-reducing and health care's effect is more magical, and huge protection and repair that health is played are very significant.The effect of Flos Lonicerae has expelling summer-heat, relieving alcoholic intoxication, cephalocathartic, quench one's thirst, remove noxious substance in the body, blood fat reducing, fat-reducing, skin cleaning and beauty, the pre-effectiveness of anti-aging, life lengthening.The blood pressure lowering of Flos Lonicerae energy, reduction serum cholesterol increase coronary flow, prevention coronary heart disease and angina cordis; Suppress the formation of cerebral thrombosis; Improve human body anoxia enduring free radical, hypermnesis, slow down aging; Improve microcirculation, remove peroxidating fat deposition, enhance metabolism, moistening skin and eliminating spot, dredge the loose evil effect of heat, to affection due to external wind and heat or epidemic febrile disease from the beginning of, fever of the body headache, dry mouth and throat etc. have certain effect.
Herba Iridis japonicae has detoxifcation, reducing swelling and alleviating pain.Treating the liver is scorching, hepatomegaly, liver pain, laryngalgia, the effects such as gastropathy.
Radix Ophiopogonis, grass had another name called dwarf lilyturf, was the draft commonly used of park and urban afforestation plantation.The Compendium of Material Medica record: " ancients only use wild survivor, and mostly later age is used is to plant to transplant to form." be important YIN nourishing and the production of body fluid promoting medicine Radix Ophiopogonis.Contain mucopolysaccharide Radix Ophiopogonis, can promote glandular secretion, to thirsty and dry pharynx, the red tongue with a little fluid that various febrile diseases cause, show as deficiency of YIN impairment of body fluid person, can be equal to usefulness with the bright Radix Rehmanniae, Rhizoma Phragmitis, Herba Dendrobii, with born fluid.Correct normal person's deficiency of YIN xerostomia, can make tea Radix Ophiopogonis and drink.
Flos Chrysanthemi not only has ornamental value, and the medicine food is double excellent, and good health-care effect is arranged.The traditional Chinese medical science is thought, the Flos Chrysanthemi cold nature, and sweet-bitter flavor enters lung, Liver Channel.Dispelling wind is arranged, and heat clearing away makes eye bright, the effects such as detoxifcation.Cure mainly headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, the diseases such as toxic swelling.Modern medicine thinks that Flos Chrysanthemi is the smart analeptic of a kind of god, can strengthen capillary resistance, delaying sanility, physical strength reinforcing.Flos Chrysanthemi not only can be made the beverage of clearing away summer-heat, and good sedation is arranged, and often eats to make people's limbs light refreshment.The fragrance of Flos Chrysanthemi has the merit of dispelling wind, suppressing the hyperactive liver, and that smells has auxiliary therapeutic action to flu, headache.Flos Chrysanthemi also is used for the treatment of affection due to external wind and heat, conjunctival congestion and swelling pain.But Flos Chrysanthemi blood pressure lowering, expansion artery, coronary heart disease, hypertension and arteriosclerosis there is preferably curative effect.
Summary of the invention
The problem to be solved in the present invention provides a kind of cleaning throat and moistening larynx that has, and treatment chronic pharyngitis and side effect is little contains buccal tablet of Fructus Momordicae and preparation method thereof.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of buccal tablet that contains Fructus Momordicae is characterized in that it is comprised of the raw material of following weight mark: Fructus Momordicae extract dry product 10-50, Flos Lonicerae extract dry product 10-35, Herba Iridis japonicae extract dry product 5-20, Radix Ophiopogonis extract dry product 5-20, Flos Chrysanthemi extract dry product 10-50, filler 5-10, sweeting agent 5-10.
A kind of buccal tablet that contains Fructus Momordicae is characterized in that it is comprised of the raw material of following weight mark: Fructus Momordicae extract dry product 15-30, Flos Lonicerae extract dry product 15-25, Herba Iridis japonicae extract dry product 10-15, Radix Ophiopogonis extract dry product 10-15, Flos Chrysanthemi extract dry product 15-30, filler 5-10, sweeting agent 5-10.
A kind of buccal tablet that contains Fructus Momordicae is characterized in that described filler is the mixture of starch and dextrin, and described sweeting agent is the mixture of mannitol, Sorbitol and maltodextrin.
A kind of preparation method that contains the Fructus Momordicae buccal tablet, it is characterized in that described Fructus Momordicae extract dry product, take Fructus Momordicae as raw material, add weight 10-15 water doubly, soaked twice of water heating and refluxing extraction 1 hour, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets the water extract dry product of Fructus Momordicae; Other extract dry product Flos Lonicerae extract dry products, Herba Iridis japonicae extract dry product, Radix Ophiopogonis extract dry product, Flos Chrysanthemi extract dry product make in the same way.
Described extract dry product is pressed following proportioning Fructus Momordicae extract dry product 10-50, Flos Lonicerae extract dry product 10-35, Herba Iridis japonicae extract dry product 5-20, Radix Ophiopogonis extract dry product 5-20, Flos Chrysanthemi extract dry product 10-50, filler 5-10, sweeting agent 5-10 mix homogeneously with batching, the ethanol that adds 70-90% is made soft material, granulate with 16 mesh sieves, drying gets dried granule; Sweet granule gets the following micropowder of particle diameter 70 μ m through pulverizing, and the ethanol that micropowder adds more than 85% is made soft material, granulates drying with the 14-20 mesh sieve; Tabletting, film coating gets final product.
Advantage and good effect that the present invention has are: owing to adopt technique scheme, carry out composite with rational proportioning Fructus Momordicae, Flos Lonicerae, Herba Iridis japonicae, Radix Ophiopogonis, Flos Chrysanthemi, brought into play advantage separately, this prescription has antiinflammation, especially for the treatment of chronic pharyngitis successful, and long-term taking has no side effect.
The specific embodiment
Embodiment 1: the Fructus Momordicae extract dry product
Method one: get 100 gram Fructus Momordicae raw materials, the water that adds 10 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 51 grams of Fructus Momordicae.
Method two: get 100 gram Fructus Momordicae raw materials, the water that adds 12 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 52.5 grams of Fructus Momordicae.
Method three: get 100 gram Fructus Momordicae raw materials, the water that adds 15 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 54 grams of Fructus Momordicae.
Embodiment 2: the Flos Lonicerae extract dry product
Method one: get 100 gram Flos Lonicerae raw materials, the water that adds 10 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 53 grams of Flos Lonicerae.
Method two: get 100 gram Flos Lonicerae raw materials, the water that adds 12 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 55 grams of Flos Lonicerae.
Method three: get 100 gram Flos Lonicerae raw materials, the water that adds 15 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 56 grams of Flos Lonicerae.
Embodiment 3: the Herba Iridis japonicae extract dry product
Method one: get 100 gram Herba Iridis japonicae raw materials, the water that adds 10 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 49 grams of Herba Iridis japonicae.
Method two: get 100 gram Herba Iridis japonicae raw materials, the water that adds 12 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 51.5 grams of Herba Iridis japonicae.
Method three: get 100 gram Herba Iridis japonicae raw materials, the water that adds 15 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 52 grams of Herba Iridis japonicae.
Embodiment 4: the Flos Chrysanthemi extract dry product
Method one: get 100 gram Flos Chrysanthemi raw materials, the water that adds 10 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 60 grams of Flos Chrysanthemi.
Method two: get 100 gram Flos Chrysanthemi raw materials, the water that adds 12 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 61.5 grams of Flos Chrysanthemi.
Method three: get 100 gram Flos Chrysanthemi raw materials, the water that adds 15 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 64 grams of Flos Chrysanthemi.
Embodiment 5: the Radix Ophiopogonis extract dry product
Method one: get 100 gram raw materials Radix Ophiopogonis, the water that adds 10 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 50 grams Radix Ophiopogonis.
Method two: get 100 gram raw materials Radix Ophiopogonis, the water that adds 12 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 52 grams of Radix Ophiopogonis.
Method three: get 100 gram raw materials Radix Ophiopogonis, the water that adds 15 times of weight, soaked 1 hour, twice of water heating and refluxing extraction, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets water extract dry product 53.5 grams of Radix Ophiopogonis.
Embodiment 6: contain the preparation of buccal tablet of Fructus Momordicae take 1g as 1 part
Take by weighing raw material: Fructus Momordicae extract dry product 10g, Flos Lonicerae extract dry product 12g, Herba Iridis japonicae extract dry product 15g, Radix Ophiopogonis extract dry product 20g, Flos Chrysanthemi extract dry product 30g, sweeting agent 5-10.Starch 2g, dextrin 3g, mannitol 2g, Sorbitol 2g and maltodextrin 4g mix homogeneously.The ethanol that adds 70-90% is made soft material, granulates with 16 mesh sieves, and drying gets dried granule; Sweet granule gets the following micropowder of particle diameter 70 μ m through pulverizing, and the ethanol that micropowder adds more than 85% is made soft material, granulates drying with the 14-20 mesh sieve; Tabletting, film coating gets final product.
Embodiment 7: contain the preparation of buccal tablet of Fructus Momordicae take 1g as 1 part
Take by weighing raw material: Fructus Momordicae extract dry product 20g, Flos Lonicerae extract dry product 10g, Herba Iridis japonicae extract dry product 5g, Radix Ophiopogonis extract dry product 5g, Flos Chrysanthemi extract dry product 50g, starch 1g, dextrin 1g, mannitol 1g, Sorbitol 1g and maltodextrin 3g mix homogeneously, the ethanol that adds 70-90% is made soft material, granulate with 16 mesh sieves, drying gets dried granule; Sweet granule gets the following micropowder of particle diameter 70 μ m through pulverizing, and the ethanol that micropowder adds more than 85% is made soft material, granulates drying with the 14-20 mesh sieve; Tabletting, film coating gets final product.
Embodiment 8: contain the preparation of buccal tablet of Fructus Momordicae take 1g as 1 part
Take by weighing raw material: Fructus Momordicae extract dry product 50g, Flos Lonicerae extract dry product 10g, Herba Iridis japonicae extract dry product 5g, Radix Ophiopogonis extract dry product 5g, Flos Chrysanthemi extract dry product 10g, starch 4g, dextrin 6g, mannitol 2g, Sorbitol 4g and maltodextrin 4g mix homogeneously, the ethanol that adds 70-90% is made soft material, granulate with 16 mesh sieves, drying gets dried granule; Sweet granule gets the following micropowder of particle diameter 70 μ m through pulverizing, and the ethanol that micropowder adds more than 85% is made soft material, granulates drying with the 14-20 mesh sieve; Tabletting, film coating gets final product.
More than one embodiment of the present of invention are had been described in detail, but described content only is preferred embodiment of the present invention, can not be considered to be used to limiting practical range of the present invention.All equalizations of doing according to the present patent application scope change and improve etc., all should still belong within the patent covering scope of the present invention.
Claims (4)
1. a buccal tablet that contains Fructus Momordicae is characterized in that it is comprised of the raw material of following weight mark: Fructus Momordicae extract dry product 10-50, Flos Lonicerae extract dry product 10-35, Herba Iridis japonicae extract dry product 5-20, Radix Ophiopogonis extract dry product 5-20, Flos Chrysanthemi extract dry product 10-50, filler 5-10, sweeting agent 5-10.
2. a kind of buccal tablet that contains Fructus Momordicae according to claim 1 is characterized in that it is comprised of the raw material of following weight mark: Fructus Momordicae extract dry product 15-30, Flos Lonicerae extract dry product 15-25, Herba Iridis japonicae extract dry product 10-15, Radix Ophiopogonis extract dry product 10-15, Flos Chrysanthemi extract dry product 15-30, filler 5-10, sweeting agent 5-10.
3. a kind of buccal tablet that contains Fructus Momordicae according to claim 1 is characterized in that described filler is the mixture of starch and dextrin, and described sweeting agent is the mixture of mannitol, Sorbitol and maltodextrin.
4. a kind of preparation method that contains the Fructus Momordicae buccal tablet according to claim 1, it is characterized in that described Fructus Momordicae extract dry product, take Fructus Momordicae as raw material, add weight 10-15 water doubly, soaked twice of water heating and refluxing extraction 1 hour, the each extraction 1-2 hour, filter, merge extractive liquid,, the relative density of measuring when being concentrated into 60 ℃ is 1.20-1.30, the ethanol that adds more than 85% is 60% to containing the alcohol amount, left standstill 48 hours, and with 100 order filter-cloth filterings, collected and filter clear liquid, the relative density of measuring when being concentrated into 60 ℃ is 1.10-1.20, concentrated solution carries out spray drying with conventional method, collects spray drying powder, gets the water extract dry product of Fructus Momordicae; Other extract dry product Flos Lonicerae extract dry products, Herba Iridis japonicae extract dry product, Radix Ophiopogonis extract dry product, Flos Chrysanthemi extract dry product make in the same way.
Described extract dry product is pressed following proportioning Fructus Momordicae extract dry product 10-50, Flos Lonicerae extract dry product 10-35, Herba Iridis japonicae extract dry product 5-20, Radix Ophiopogonis extract dry product 5-20, Flos Chrysanthemi extract dry product 10-50, filler 5-10, sweeting agent 5-10 mix homogeneously with batching, the ethanol that adds 70-90% is made soft material, granulate with 16 mesh sieves, drying gets dried granule; Dried granule gets the following micropowder of particle diameter 70 μ m through pulverizing, and the ethanol that micropowder adds more than 85% is made soft material, granulates drying with the 14-20 mesh sieve; Tabletting, film coating gets final product.
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| CN110637905A (en) * | 2019-09-26 | 2020-01-03 | 宁波德康生物制品有限公司 | Substitutional tea for treating pharyngitis and preparation method thereof |
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2011
- 2011-07-21 CN CN 201110204301 patent/CN102885967A/en active Pending
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