CN102871020A - Nutrient solution for conditioning gastrointestinal function and preparation method thereof - Google Patents
Nutrient solution for conditioning gastrointestinal function and preparation method thereof Download PDFInfo
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- CN102871020A CN102871020A CN2012103900614A CN201210390061A CN102871020A CN 102871020 A CN102871020 A CN 102871020A CN 2012103900614 A CN2012103900614 A CN 2012103900614A CN 201210390061 A CN201210390061 A CN 201210390061A CN 102871020 A CN102871020 A CN 102871020A
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Abstract
The invention discloses nutrient solution for conditioning a gastrointestinal function and a preparation method thereof. Each 100ml of normal saline comprises 5000-10000mg of protein, 0.3-0.6mg of vitamine A, 0.025-0.05mg of vitamine D, 800-1200mg of glutamine, 2-3mg of vitamine B1, 2-3mg of vitamine B2, 2-3mg of vitamine B6, 100-200mg of vitamine C, 10-20mg of vitamine E, 0.1-0.2mg of folic acid, 200-400mg of calcium, 3-6mg of iron, 3-6mg of zinc, 0.03-0.04mg of selenium, 30000000-60000000CFU of probiotics, and 10000-20000g of lactulose. The preparation method comprises the steps of: taking 100ml of normal saline at 40-50 DEG C, orderly adding albumen powder and each component to uniformly agitate, and finally adding probiotics and lactulose to dissolve and modulate. The nutrient solution provides sufficient nutrition, does not aggravate the burden of an intestinal tract, adjusts and repairs flora and mucous membranes at different parts of the gastrointestinal tracts of a patient, and improves the barrier function of each mucous membrane of the intestinal track so as to enhance absorption of nutrient elements.
Description
Technical field
The present invention relates to the clinical nutriology field, be specifically related to nutrient solution of a kind of patient's gastrointestinal function conditioning and preparation method thereof.
Background technology
Patient's gastrointestinal dysfunction is one of modal clinical problem, generally payes attention to for the clinician at present.Patient's gastrointestinal dysfunction has influence on patient's nutrition, barrier, immunity, directly has influence on lapsing to of patient.When gastrointestinal function generation obstacle, digestion and absorption function has and obviously goes down or completely lose, and not only can cause the nutritional deficiency of body, resistance to descend, and can have influence on patient's psychology, makes its rehabilitation slow.Undoubtedly, nutritional support is a requisite treatment measure to gastrointestinal dysfunction.Since the eighties in 20th century, the advantage of EA is familiar with gradually, and research thinks that EA except supplying with nutrition, also has the special role that promotes the intestinal mucosa growth, is conducive to intestinal function recovery.But for the treatment of gastrointestinal dysfunction, there is no effect method so far.Someone adopts the various nutrient elements prescription of easy absorption, although can partly improve the nutrition situation, does not fundamentally improve patient's gastrointestinal function, and if any accidentally, also can add heavy patient's enteron aisle burden.Therefore, invent a kind of conditioning nutrient solution of suitable treatment patient gastrointestinal dysfunction, become one of clinical nutrition major issue in the urgent need to address.
Summary of the invention
The invention provides a kind of conditioning nutrient solution of supplemental treatment patient's gastrointestinal dysfunction, make the gastrointestinal dysfunction patient by taking special preparation nutrient solution and the relevant non-pharmaceutical means such as nutrition guide improve patient's trophic level and gastrointestinal function, improve patient's gut barrier function and body immunity, be conducive to lapsing to of patient, thereby improve patient's life quality, shorten the hospital stays, alleviate patient family, society and national burden.
The present invention also provides a kind of method for preparing the conditioning nutrient solution of supplemental treatment patient gastrointestinal dysfunction.
For achieving the above object, the technical solution used in the present invention is:
Patient's gastrointestinal function conditioning nutrient solution of the present invention comprises following active ingredient in per 100 ml physiological salines:
A, nutrient
The method that preparation of the present invention contains patient's gastrointestinal function conditioning nutrient solution of above-mentioned active ingredient is:
At first getting temperature is 40~50 ℃ of 100 ml physiological saline, add in the albumen powder, stir, add successively again vitamin A, vitamin D, vitamin C, vitamin E, vitamin B compound, folic acid, glutamine, calcium citrate, ferrum citricum, zinc citrate, sodium selenate, the limit edged stirs, add at last probio and lactulose, the mixed dissolution modulation forms.
Described physiological saline concentration is 0.9wt%.
Further, described calcium citrate also can be calcium lactate; Described ferrum citricum also can be ferrous lactate or ferrous sulfate; Described zinc citrate also can be zinc lactate or zinc gluconate.
Described probio is comprised of in Bacillus acidi lactici, Bifidobacterium, the streptococcus fecalis one or more.
Further, described probio is comprised of Bacillus acidi lactici, Bifidobacterium and streptococcus fecalis.
Preferably, the ratio of Bacillus acidi lactici, Bifidobacterium and streptococcus fecalis is 1:1:1 in the described probio.
Patient's gastrointestinal function conditioning nutrient solution mechanism of action of the present invention is: cause the gastrointestinal function obstacle for chronic patient and critically ill patient owing to disease, the Abwehrkraft des Koepers that causes when health nutritional deficiency and intestinal mucosa barrier function obstacle occurring descends, replenish the nutrient that lacks by this nutrient solution, improve the nutrition condition of body and promote the intestinal mucosa growth, improve Abwehrkraft des Koepers and improve mucosal barrier function.
Owing to having adopted above-mentioned technical scheme, gastrointestinal function conditioning nutrient solution of the present invention is compared with nutrient solution of the prior art and is had the following advantages and effect:
The proportioning of all kinds of nutrients of gastrointestinal function conditioning nutrient solution of the present invention is suitable, and adds probio and the lactulose that promotes digestion and the growth of promotion intestinal mucosa, improves function of intestinal canal.This gastrointestinal function conditioning nutrient solution comprehensive nutrition, each nutrient configuration rationally, for patient's because the characteristics that disease causes gastrointestinal dysfunction, the resistance of the body that causes when health nutritional deficiency and intestinal mucosa barrier function obstacle occurring descends, abundant nutrition can be provided, do not increase the weight of the enteron aisle burden, again flora and the mucous membrane of the GI different parts of patient are adjusted and repaired, make it closer to ecosystem and improve by the have additional nutrients absorption of element of intestinal mucosa barrier function.Simultaneously mouthfeel good, relax bowel.This nutrient solution is that edible safety has no side effect according to the preparation of patient's characteristics.
The specific embodiment
Patient's gastrointestinal function conditioning nutrient solution of the present invention comprises following active ingredient in per 100 ml physiological salines:
A, nutrient
The method that preparation of the present invention contains patient's gastrointestinal function conditioning nutrient solution of above-mentioned active ingredient is:
At first getting temperature is 40~50 ℃ of 100 ml physiological saline, add in the albumen powder, stir, add successively again vitamin A, vitamin D, vitamin C, vitamin E, vitamin B compound, folic acid, glutamine, calcium citrate, ferrum citricum, zinc citrate, sodium selenate, the limit edged stirs, add at last probio and lactulose, the mixed dissolution modulation forms.
Described physiological saline concentration is 0.9wt%.
Further, described calcium citrate can also be calcium lactate; Described ferrum citricum can also be ferrous lactate or ferrous sulfate; Described zinc citrate can also be zinc lactate or zinc gluconate.
Described probio is comprised of in Bacillus acidi lactici, Bifidobacterium, the streptococcus fecalis one or more.
Further, described probio is comprised of Bacillus acidi lactici, Bifidobacterium and streptococcus fecalis.
Preferably, the ratio of Bacillus acidi lactici, Bifidobacterium and streptococcus fecalis is 1:1:1 in the described probio.
The invention discloses nutrient solution prescription of gastrointestinal function conditioning and preparation method thereof, those skilled in the art can use for reference this paper content, are suitably improved.Special needs to be pointed out is, all similarly replace and change apparent to those skilled in the art, and they all are deemed to be included among the present invention.Application of the present invention is described by preferred embodiment, and the related personnel obviously can change or suitably change and combination application as herein described within not breaking away from content of the present invention, spirit and scope, realizes and use the technology of the present invention.
Each used component has the product of single form in the gastrointestinal function conditioning nutrient solution prescription preparation process of the present invention, can be by having bought on the market.
Below in conjunction with embodiment, further set forth the present invention:
According to patient's concrete condition, the consumption of capable of regulating prescription.
Embodiment 1, critical illness patient intestines function conditioning nutrient solution and preparation method thereof.
A, nutrient
At first getting temperature is the physiological saline of 40~50 ℃ of 100 milliliters of 0.9wt%, add in the albumen powder, stir, add successively again vitamin A, vitamin D, vitamin C, vitamin E, vitamin B compound, folic acid, glutamine, calcium citrate, ferrum citricum, zinc citrate, sodium selenate, the limit edged stirs, the ratio that adds at last Bacillus acidi lactici, Bifidobacterium and streptococcus fecalis is probio and the lactulose of 1:1:1, and the mixed dissolution modulation forms.
Embodiment 2, the elderly patients intestines function conditioning nutrient solution and preparation method thereof.
At first getting temperature is the physiological saline of 40~50 ℃ of 100 milliliters of 0.9wt%, add in the albumen powder, stir, add successively again vitamin A, vitamin D, vitamin C, vitamin E, vitamin B compound, folic acid, glutamine, calcium citrate, ferrum citricum, zinc citrate, sodium selenate, the limit edged stirs, the ratio that adds at last Bacillus acidi lactici, Bifidobacterium and streptococcus fecalis is probio and the lactulose of 1:1:1, and the mixed dissolution modulation forms.
Embodiment 3, general chronic patient intestines function conditioning nutrient solution and preparation method thereof.
A, nutrient
At first getting temperature is the physiological saline of 40~50 ℃ of 100 milliliters of 0.9wt%, add in the albumen powder, stir, add successively again vitamin A, vitamin D, vitamin C, vitamin E, vitamin B compound, folic acid, glutamine, calcium citrate, ferrum citricum, zinc citrate, sodium selenate, the limit edged stirs, the ratio that adds at last Bacillus acidi lactici, Bifidobacterium and streptococcus fecalis is probio and the lactulose of 1:1:1, and the mixed dissolution modulation forms.
Embodiment 4, the elderly patients intestines function conditioning nutrient solution and preparation method thereof.
A, nutrient
At first getting temperature is the physiological saline of 40~50 ℃ of 100 milliliters of 0.9wt%, add in the albumen powder, stir, add successively again vitamin A, vitamin D, vitamin C, vitamin E, vitamin B compound, folic acid, glutamine, calcium lactate, ferrous lactate, zinc lactate, sodium selenate, the limit edged stirs, add at last Bacillus acidi lactici and lactulose, the mixed dissolution modulation forms.
Embodiment 5, the elderly patients intestines function conditioning nutrient solution and preparation method thereof.
A, nutrient
At first getting temperature is the physiological saline of 40~50 ℃ of 100 milliliters of 0.9wt%, add in the albumen powder, stir, add successively again vitamin A, vitamin D, vitamin C, vitamin E, vitamin B compound, folic acid, glutamine, calcium lactate, ferrous sulfate, zinc gluconate, sodium selenate, the limit edged stirs, the ratio that adds at last Bifidobacterium and streptococcus fecalis is probio and the lactulose of 1:1, and the mixed dissolution modulation forms.
The Clinical analysis for the treatment of of the present invention and regulating gastointestinal function obstacle sees attached list 1:
The stomach and intestine merit that table 1 is taken special preparation hinders conditioning nutrient solution and treatment of control group effect relatively
Subordinate list shows, taking the nutrient solution of special preparation and the general nutrition treatment effect of control group can find out in relatively, patient's metabolic capability, stool situation and the lymphocyte of taking the nutrient solution of special preparation all is significantly improved, the efficient of indices all reaches more than 80%, and this serial application result shows that the chronic patient of taking this nutrient solution and nutrition condition, life quality, the immunologic function of critically ill patient all have clear improvement.
This nutrient solution has special nutritive validity to chronic patient and critically ill patient, the probio and the lactulose that add are adjusted flora and the mucous membrane of patient's GI different parts, make it closer to ecosystem and improve by the have additional nutrients absorption of element of intestinal mucosa barrier function.The helpful body immunity that improves of its function improves patient's trophic level and gut barrier function.
Patient can select the nutrient solution of various dose as the case may be, as replenishing of normal diet.To patient occur that nutrient lacks and malnutritive intestinal mucosa barrier function obstacle have certain prevention, conditioning and a therapeutic action, have no side effect, can long-term taking.
In sum, the proportioning of all kinds of nutrients of gastrointestinal function conditioning nutrient solution of the present invention is suitable, and adds probio and the lactulose that promotes digestion and the growth of promotion intestinal mucosa, improves function of intestinal canal.This gastrointestinal function conditioning nutrient solution comprehensive nutrition, each nutrient configuration rationally, for patient's because the characteristics that disease causes gastrointestinal dysfunction, the resistance of the body that causes when health nutritional deficiency and intestinal mucosa barrier function obstacle occurring descends, abundant nutrition can be provided, do not increase the weight of the enteron aisle burden, again flora and the mucous membrane of the GI different parts of patient are adjusted and repaired, make it closer to ecosystem and improve by the have additional nutrients absorption of element of intestinal mucosa barrier function.Simultaneously mouthfeel good, relax bowel.This nutrient solution is that edible safety has no side effect according to the preparation of patient's characteristics.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned example embodiment, and in the situation that do not deviate from spirit of the present invention or essential characteristic, can realize the present invention with other concrete form.Therefore, no matter from which point, all should regard embodiment as exemplary, and be nonrestrictive, scope of the present invention is limited by claims rather than above-mentioned explanation, therefore is intended to include in the present invention dropping on the implication that is equal to important document of claim and all changes in the scope.Any Reference numeral in the claim should be considered as limit related claim.
In addition, be to be understood that, although this specification is described according to embodiment, but be not that each embodiment only comprises an independently technical scheme, this narrating mode of specification only is for clarity sake, those skilled in the art should make specification as a whole, and the technical scheme among each embodiment also can through appropriate combination, form other embodiments that it will be appreciated by those skilled in the art that.
Claims (9)
1. a gastrointestinal function conditioning nutrient solution is characterized in that, comprises following active ingredient in per 100 ml physiological salines:
A, nutrient
2. method for preparing gastrointestinal function conditioning nutrient solution claimed in claim 1, it is characterized in that: at first getting temperature is 40~50 ℃ of 100 ml physiological saline, add in the albumen powder, stir, add successively again vitamin A, vitamin D, vitamin C, vitamin E, vitamin B compound, folic acid, glutamine, calcium citrate, ferrum citricum, zinc citrate, sodium selenate, the limit edged stirs, and adds at last probio and lactulose, and the mixed dissolution modulation forms.
3. the method for preparing the gastrointestinal function conditioning nutrient solution according to claim 2, it is characterized in that: described physiological saline concentration is 0.9wt%.
4. the method for preparing the gastrointestinal function conditioning nutrient solution according to claim 2, it is characterized in that: described calcium citrate also can be calcium lactate.
5. the method for preparing the gastrointestinal function conditioning nutrient solution according to claim 2, it is characterized in that: described ferrum citricum also can be ferrous lactate or ferrous sulfate.
6. the method for preparing the gastrointestinal function conditioning nutrient solution according to claim 2, it is characterized in that: described zinc citrate also can be zinc lactate or zinc gluconate.
7. the method for preparing the gastrointestinal function conditioning nutrient solution according to claim 2 is characterized in that: described probio is comprised of in Bacillus acidi lactici, Bifidobacterium, the streptococcus fecalis one or more.
8. the method for preparing the gastrointestinal function conditioning nutrient solution according to claim 7, it is characterized in that: described probio is comprised of Bacillus acidi lactici, Bifidobacterium and streptococcus fecalis.
9. the method for preparing the gastrointestinal function conditioning nutrient solution according to claim 8, it is characterized in that: the ratio of Bacillus acidi lactici, Bifidobacterium and streptococcus fecalis is 1:1:1 in the described probio.
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Cited By (4)
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CN104082750A (en) * | 2014-06-11 | 2014-10-08 | 南通昊友食品添加剂有限公司 | Multifunctional composite food nutrition enhancer |
CN104223093A (en) * | 2014-06-11 | 2014-12-24 | 南通昊友食品添加剂有限公司 | Compound food nutrient supplement |
CN106722925A (en) * | 2016-11-14 | 2017-05-31 | 张涛 | Health food with intestinal regulatory function and preparation method thereof |
WO2018197087A1 (en) * | 2017-04-28 | 2018-11-01 | Fresenius Kabi Austria Gmbh | Compositions comprising lactulose for maintaining or improving gut health in humans |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104082750A (en) * | 2014-06-11 | 2014-10-08 | 南通昊友食品添加剂有限公司 | Multifunctional composite food nutrition enhancer |
CN104223093A (en) * | 2014-06-11 | 2014-12-24 | 南通昊友食品添加剂有限公司 | Compound food nutrient supplement |
CN106722925A (en) * | 2016-11-14 | 2017-05-31 | 张涛 | Health food with intestinal regulatory function and preparation method thereof |
WO2018197087A1 (en) * | 2017-04-28 | 2018-11-01 | Fresenius Kabi Austria Gmbh | Compositions comprising lactulose for maintaining or improving gut health in humans |
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Application publication date: 20130116 |