CN102861269A - Drug combination for treating acne - Google Patents

Abstract

The invention discloses a drug combination for treating acne, which is prepared with the following materials in parts by weight: 18 to 22 parts of honeysuckle, 18 to 22 parts of cicada slough, 10 to 15 parts of white mulberry root-bark, 10 to 15 parts of loquat leaf, 15 to 20 parts of glabrous greenbrier rhizome, 8 to 12 parts of divaricate saposhnikovia root, 12 to 18 parts of Chinese magnoliavine fruit, 10 to 20 parts of coix seed, 15 to 20 parts of heartleaf houttuynia herb, 5 to 15 parts of purslane herb, 25 to 30 parts of lily, 15 to 25 parts of Chinese yam and 20 to 30 parts of baical skullcap root. When the drug combination is used for treating acne, the course of treatment is short, the drug combination can rapidly take effect, the curative effect is good, the cure rate is high, and acne cannot easily recur.

Description

A kind of pharmaceutical composition of Acne treatment

Technical field

The present invention relates to a kind of pharmaceutical composition of Acne treatment, especially a kind of Chinese medicine composition of Acne treatment.

Background technology

Acne is a kind of chronic inflammatory disease illness of pilosebaceous unit structure, mainly betides face and thoracic dorsal etc. and locates, and shows as blackhead, inflammatory pimple, secondary pustule or tuberosity, cyst etc.Chinese medicine is called: " rosacea caused by lung-wind ", " pimples ", and how because of eating and drinking without temperance, surfeit delicious food savoury, the lung stomach is damp and hot, feels ailment said due to cold or exposure again and falls ill.After being apt to occur in buccal, chin, nose buccal groove, ear, chest, back and buttocks.After the adolescence, mostly naturally alleviate or fully recover.

Acne is apt to occur in and contains maximum, the abundantest sebaceous gland zone on the body skin, such as face, anterior part of chest, shoulder back and upper arm parts etc., how relevant with factors such as endocrine heredity, diet, spirit, but its Etiological pathology: the dyskeratosis of (1) follicular orifice causes follicular orifice to block.(2) androgen secretion too much stimulates responsive sebaceous gland, causes the sebaceous gland sebum secretion to increase, and the sebaceous gland cast that increases blocks follicular orifice; (3) propionic acid bacillus excessive multiplication in the hair follicle discharges too much multiple inflammatory material, makes hair follicle and hair follicle surrounding skin inflamed, forms pustule or acne cystica.Clinical pustule and tuberosity or cyst with hoary hair and blackhead, red pimple, suppuration.And inflammatory papular type and purulence papular type can cause erythema, pigmentation after the inflammation; the acne of nodular type, pustule type, cyst type and cicatrix type particularly; more often can stay the sequela such as pothole, Accretive Type cicatrix or keloid after, cause disfeaturing property consequence, cause repent forever.Acne belongs to motherland's medical science " pimples " category, thinks that the heart, lung meridian heat in blood pent up due to the face.

Acne treatment mainly for the reason of morbidity, at first will suppress the secretion of sebaceous gland at present, alleviates the follicular keratosis phenomenon, and it is unimpeded that skin is drained, and kills propionibacterium acnes again, cooperates anti-inflammatory drug to treat.General employing medicine for external use and oral medicine cooperate treats, and adds the medicine of vitamins and jointly adjusts endocrine.Present medicine on the market is very fast to the clinical symptom remission of acne, but long-term effect is not remarkable, and cure rate is low, and relapse rate is higher, does not reach too gratifying curative effect.

Summary of the invention

The objective of the invention is in order to provide a kind of short treating period, instant effect, good effect, the pharmaceutical composition of the Acne treatment of cure rate height and difficult recurrence.With medicine composite for curing acne of the present invention, short treating period, instant effect, good effect, the high and difficult recurrence of cure rate.

To achieve these goals, the present invention adopts following technical scheme: a kind of pharmaceutical composition of Acne treatment is formed by the preparation of raw material of following weight portion:

Flos Lonicerae 18-22 part, Periostracum Cicadae 18-22 part, Cortex Mori 10-15 part, Folium Eriobotryae 10-15 part, native Siberian cocklebur Siberian cocklebur 15-20 part,

Radix Saposhnikoviae 8-12 part, Fructus Schisandrae Chinensis 12-18 part, Semen Coicis 10-20 part, Herba Houttuyniae 15-20 part, Herba Portulacae 5-15 part,

Bulbus Lilii 25-30 part, Rhizoma Dioscoreae 15-25 part, Radix Scutellariae 20-30 part.

Aforementioned pharmaceutical compositions is the prestige by the preparation of raw material of following weight portion preferably:

20 parts of Flos Loniceraes, 18 parts of Periostracum Cicadaes, 12 parts of Cortex Mori, 10 parts of Folium Eriobotryaes, 20 parts of native Siberian cocklebur Siberian cockleburs,

12 parts of Radix Saposhnikoviaes, 12 parts of Fructus Schisandrae Chinensis, 20 parts of Semen Coiciss, 15 parts of Herba Houttuyniae, 12 parts of Herba Portulacaes,

25 parts of Bulbus Liliies, 20 parts of Rhizoma Dioscoreaes, 20 parts of Radix Scutellariaes.

Aforementioned pharmaceutical compositions can be made into pharmaceutically acceptable dosage form, such as water preparation, and granule, capsule or tablet etc.

Clinical observation:

Case quantity 500 examples.Age 15-45 year, 25 years old mean age.The course of disease is the longest 25 years, the shortest half a year.Male's 318 examples wherein; Women's 182 examples adopt medicine composite for curing of the present invention, and concrete parts by weight are finely tuned in the above-mentioned composition scope according to patient's physical condition.Therefore the almost non-toxic side effect of pharmaceutical composition of the present invention, until recovery from illness generally can be fully recovered in 2-4 week, is followed up a case by regular visits to after 5 months at fixing course for the treatment of not.

Diagnostic criteria:

Clinical condition of illness: face, the shirtfront, the back, hoary hair, blackhead, red pimple appear in the position skins such as upper arm, or purulence pimple or pustule.Clamp enter a profession tuberosity or cyst type tuberosity, struvite erythema appears in the lesions position skin, tuberosity, and inflammation pigmentation or cicatrix occur after eliminating, and whole body shows as oily skin.

Sign: whole skin is greasy, and the struvite tuberosity tenderness of projection is obvious, the focus surface irregularity.

(1) recovery from illness: the pars affecta skin full recovery is normal, with the zero difference (the cicatrix pigmentations that the indivedual healings of depolarization stay disappear outer not yet fully) relatively of healthy skin on every side.Skin surface is smooth, and smegma obviously reduces.

(2) effective: pars affecta skin surface pimple, relatively there is obvious minimizing to alleviate before tuberosity and cyst and the treatment, the lesions position pustule, purulence pimple and struvite pimple significantly alleviate.Leave obvious pigmentation or pothole, hypertrophic cicatrix and keloid after the part healing.

(3) invalid: ill skin focus relatively increases the weight of without alleviating or having with treatment is front, or again recurrence more.

Type of effect	Case (sum 500)	Ratio
			Recovery from illness	482	96.4％
Effectively	15	3％
			Invalid	3	0.6％

The specific embodiment

Embodiment 1

Flos Lonicerae 20g, Periostracum Cicadae 18g, Cortex Mori 12g, Folium Eriobotryae 10g, native Siberian cocklebur Siberian cocklebur 20g, Radix Saposhnikoviae 12g, Fructus Schisandrae Chinensis 12g, Semen Coicis 20g, Herba Houttuyniae 15g, Herba Portulacae 12g, Bulbus Lilii 25g, Rhizoma Dioscoreae 20g, Radix Scutellariae 20g decocts with water and makes decoction, three times on the one.

Embodiment 2

Flos Lonicerae 18g, Periostracum Cicadae 20g, Cortex Mori 12g, Folium Eriobotryae 12g, native Siberian cocklebur Siberian cocklebur 18g, Radix Saposhnikoviae 12g, Fructus Schisandrae Chinensis 15g, Semen Coicis 12g, Herba Houttuyniae 18g, Herba Portulacae 10g, Bulbus Lilii 25g, Rhizoma Dioscoreae 18g, Radix Scutellariae 20g pulverizes, and granulates, and sieves granulation agent, three times on the one.

Embodiment 3

Flos Lonicerae 18g, Periostracum Cicadae 20g, Cortex Mori 12g, Folium Eriobotryae 12g, native Siberian cocklebur Siberian cocklebur 18g, Radix Saposhnikoviae 12g, Fructus Schisandrae Chinensis 15g, Semen Coicis 12g, Herba Houttuyniae 18g, Herba Portulacae 10g, Bulbus Lilii 25g, Rhizoma Dioscoreae 18g, Radix Scutellariae 20g pulverizes, and is encapsulated, three times on the one.

Should be noted that above-described embodiment only is for example of the present invention clearly is described, and be not limitation of the invention.For those of ordinary skill in the field, can also make on the basis of the above description other multi-form variation or changes.And the apparent variation of being amplified out thus or change still are among protection scope of the present invention.

Claims (4)

1. the pharmaceutical composition of an Acne treatment is characterized in that, described pharmaceutical composition is formed by the preparation of raw material of following weight portion:

Flos Lonicerae 18-22 part, Periostracum Cicadae 18-22 part, Cortex Mori 10-15 part, Folium Eriobotryae 10-15 part, native Siberian cocklebur Siberian cocklebur 15-20 part,

Radix Saposhnikoviae 8-12 part, Fructus Schisandrae Chinensis 12-18, Semen Coicis 10-20 part, Herba Houttuyniae 15-20 part, Herba Portulacae 5-15 part,

Bulbus Lilii 25-30 part, Rhizoma Dioscoreae 15-25 part, Radix Scutellariae 20-30 part.

2. the pharmaceutical composition of Acne treatment is as claimed in claim 1 formed by the preparation of raw material of following weight portion:

20 parts of Flos Loniceraes, 18 parts of Periostracum Cicadaes, 12 parts of Cortex Mori, 10 parts of Folium Eriobotryaes, 20 parts of native Siberian cocklebur Siberian cockleburs,

12 parts of Radix Saposhnikoviaes, Fructus Schisandrae Chinensis 12,20 parts of Semen Coiciss, 15 parts of Herba Houttuyniae, 12 parts of Herba Portulacaes,

25 parts of Bulbus Liliies, 20 parts of Rhizoma Dioscoreaes, 20 parts of Radix Scutellariaes.

3. such as each described pharmaceutical composition of claim 1-2, described pharmaceutical composition can be made into pharmaceutically acceptable dosage form.

4. pharmaceutical composition as claimed in claim 3, wherein pharmaceutically acceptable dosage form is selected from water preparation, granule, capsule or tablet.