CN102861198A - Pure traditional Chinese medicine preparation for treating cirrhosis with ascites - Google Patents
Pure traditional Chinese medicine preparation for treating cirrhosis with ascites Download PDFInfo
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- CN102861198A CN102861198A CN2012103566549A CN201210356654A CN102861198A CN 102861198 A CN102861198 A CN 102861198A CN 2012103566549 A CN2012103566549 A CN 2012103566549A CN 201210356654 A CN201210356654 A CN 201210356654A CN 102861198 A CN102861198 A CN 102861198A
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Abstract
The invention belongs to the field of medicinal preparation, in particular to a pure traditional Chinese medicine preparation for treating cirrhosis with ascites, which is characterized by comprising the following raw materials by weight: 40 to 50 parts of scirpus tabernaemontani, 15 to 21 parts of radix astragali, 20 to 26 parts of herba elsholtziae, 12 to 18 parts of fructus lycii, 16 to 24 parts of houttuynia cordata, 70 to 80 parts of zaocys dhumnade and 5 to 11 parts of liquorice. The pure traditional Chinese medicine preparation inherits the tradition of treating both symptoms and root causes in the traditional Chinese medical science, is the safe and high efficient pure traditional Chinese medicine preparation with the characteristics of being convenient to take, short in course of treatment, high in cure rate and taking effect quickly and the like. The effect can be produced after the general patients take the pure traditional Chinese medicine preparation for three to five days, ascites can be drained out for about 20 days, and the clinical healing level can be reached after the general patients are subjected to consolidated therapy for one to two months.
Description
Technical field
The invention belongs to field of pharmaceutical preparations, relate in particular to a kind of pharmaceutical preparation for the treatment of cirrhotic ascites.
Background technology
Cirrhotic ascites refers to because the liver that causes of hepatic disease inflammation repeatedly, after fibrosis and liver cirrhosis form because multiple pathological factor: the clinical symptoms that causes the intraperitoneal hydrops such as portal hypertension, hypoproteinemia, water-sodium retention etc.Cirrhotic ascites is not an independent disease, but the common clinical in many hepatic disease whole latter stages.Cause that the cirrhotic ascites common disease has: B-mode, hepatitis C, alcoholic hepatitis, autoimmune hepatitis etc.In a single day hepatic disease is developed to the cirrhotic ascites stage, shows that sclerosis arrived the compensatory phase of losing, and must carry out the active intervention treatment.The traditional Chinese medical science thinks that cirrhotic ascites is to be subjected to disease by liver, lung, kidney, cause the water-electrolyte metabolism obstacle in gas, blood, the water alluvial body, cause stagnation of QI due to depression of the liver blood stasis, the hepatic and renal YIN deficiency, deficiency of spleen-YANG and kidneyYANG, retention of water-damp in the body, need to nurse one's health on the whole, treat with blood stasis dispelling, invigorate the spleen and warm the kidney, blood stasis dispelling row water by regulating the flow of QI to dissipate blood stasis, Clearing heat and removing obstruction of fu-organs, blood circulation promoting and blood stasis dispelling, replenishing QI to invigorate the spleen, inducing diuresis to remove edema, yin nourishing diuretic, assistant.But the pure Chinese medicinal preparation effect that is used for the treatment of clinically cirrhotic ascites at present is poor, can not carry out on the whole the recovery of function to patient's liver organ.
Chinese patent CN101934029A discloses a kind of " a kind of Chinese medicine for the treatment of cirrhotic ascites ", is made by the raw material of following parts by weight: Herba Patriniae 2～15, Radix Bupleuri 2～15, Rhizoma Polygonati 2～10, Fructus Chaenomelis 2～15, Ganoderma 2～15.This invention has no side effect for pure Chinese medicinal preparation, can treat cirrhotic ascites, but its administration time is longer, and onset is slow, and takes inconvenience.
Summary of the invention
In order to solve the problems of the technologies described above, the invention provides a kind of pure Chinese medicinal preparation for the treatment of cirrhotic ascites, it is characterized in that: comprise by weight Herba Scirpi Tabernaemontani 40-50 part, Radix Astragali 15-21 part, Herba Moslae 20-26 part, Fructus Lycii 12-18 part, Herba Houttuyniae 16-24 part, Zaocys 70-80 part, Radix Glycyrrhizae 5-11 part.
Described parts by weight are 45 parts of Herba Scirpi Tabernaemontanis, 18 parts of the Radixs Astragali, 23 parts of Herba Moslaes, 15 parts of Fructus Lycii, 20 parts of Herba Houttuyniae, 75 parts of Zaocyss, 8 parts in Radix Glycyrrhizae.
Beneficial effect of the present invention is: Herba Scirpi Tabernaemontani is cool in nature, sweet in the mouth, lightly seasoned, have no side effect, effect with diuretic, eliminating dampness by diuresis, heat clearing away, protection hepatocyte, inhibition hepatocellular apoptosis, promotion liver cell regeneration, be used for liver cirrhosis and ascites, have the effect of adjusting on the whole liver damage function and treating both the principal and secondary aspects of a disease; The Radix Astragali contains the various trace elements such as Saponin, sucrose, polysaccharide, several amino acids, folic acid and selenium, zinc, copper, the enhancing human body immunity function arranged, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely, can significantly promote the renewal of serum and hepatic protein; Herba Moslae can diaphoresis during expelling summer-heat, row water wet dissipation, stomach warming transfer, and is evident in efficacy to feeling of stuffiness in chest stomachache, vomiting and diarrhoea, edema; Fructus Lycii nourishing the liver and kidney, replenishing vital essence to improve eyesight, to asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat quench one's thirst, blood deficiency and yellow complexion, blurred vision be not clear evident in efficacy, its beet alkali hydrochlorate that contains, lycium barbarum polysaccharide can anti-liver injuries, have the function of protecting the liver; Herba Houttuyniae heat-clearing and toxic substances removing, removing pus and relieving carbuncle, inducing diuresis for treating stranguria syndrome; The Zaocys sweet in the mouth, property is put down, contain lysine, leucine, aspartic acid, glutamic acid, glycine, alanine, threonine, green propylhomoserin, cystine, valine, tyrosine, methionine, isoleucine, phenylalanine, histidine, through propylhomoserin, 17 seed amino acids such as proline, during taking off, Serpentis contains ossein, contain the fruit diphosphatase in the muscle, tropomyosin etc., contain cholic acid in the Fel Serpentis, insulin, has stronger antiinflammatory action, its antiinflammatory action intensity is equivalent to the hydrocortisone of 15mg/kg, have significant analgesic activity, action intensity is equivalent to the Hyndarin of 40mg/kg; Radix Glycyrrhizae property is flat, sweet in the mouth, return 12 warps, the effects such as invigorating the spleen and replenishing QI, relieving cough and moistening lung, emergency detoxifcation, mediation hundred medicines, protecting liver and detoxication, blood fat reducing and atherosclerosis and enhancing immunologic function are arranged, the active ingredient of Detoxication is glycyrrhizin, detoxification machine is made as glycyrrhizin hydrolyzate glucuronic acid and can be combined with poisonous substance, and glycyrrhizin has the effect of comprehensive function at the aspects such as detoxification ability that strengthen liver.The tradition of effecting a permanent cure of effecting a permanent cure and asking the source, focus on internal organs according to the Chinese traditional treatment disease, established the prescription rule of nourishing the five internal organs, resolving depression regulating QI, soft liver easing the affected liver, eliminating dampness and diuresis, the present invention not only have protect the liver, nourishing the liver, the hepatocellular regeneration of promotion and repair function, and the detoxicating, relieving inflammation effect arranged, can effectively improve the blood circulation of the internal organs such as liver,spleen,kidney, stomach, intestinal, fall enzyme, eliminating dampness by diuresis and diuretic effect and stablize rapidly; Broken traditional treatment cirrhotic ascites method, it or not simple diuretic, mend energy and blood of human body but focus on to transfer, equilibrium between yin and yang in the integrally-regulated body of liver, the resistance against diseases of enhancing body increases the blood flow that liver,kidney,spleen, stomach etc. are organized, and improves the liver Nutrition and Metabolism, the hepatic tissue of damaged is protected and repaired, thereby reach the purpose of fundamentally curing liver cirrhosis, hepatic ascites; Have stronger antivirus action, can stop and suppress virus the copying of liver, remove in a short time the inside and outside various viruses of hepatocyte, promote hepatocellular regeneration capacity, recover hepatocellular normal function, from the source with fundamentally cure liver cirrhosis, hepatic ascites.Verify for many years through liver cirrhosis, hepatic ascites patient and to show, said preparation can have efficient recovery and improve the function and activity of liver, the symptoms such as the ascites that elimination causes because of liver cirrhosis, portal hypertension, fatigue and weak and inappetence, especially eliminate ascites, to recover the aspects such as hepatocyte activity, Control in recurring and health invigorating remarkably productive, inherited the tradition of traditional Chinese medical science treating both the principal and secondary aspects of a disease; Said preparation has short treating period, instant effect, cure rate high, and general patient's medication can take effect in three to five days, and left and right sides ascites can be drained in 20 days, again after treatment one or two month, can reach the clinical cure level; The present invention is pure Chinese medicinal preparation, and is safe and efficient, taking convenience.
The specific embodiment
Embodiment one
Select Herba Scirpi Tabernaemontani, the Radix Astragali, Herba Moslae, Fructus Lycii, Herba Houttuyniae, Zaocys, Radix Glycyrrhizae is crude drug, concoct according to selected each component of following parts by weight: 43 parts of Herba Scirpi Tabernaemontanis, 16 parts of the Radixs Astragali, 22 parts of Herba Moslaes, 13 parts of Fructus Lycii, 18 parts of Herba Houttuyniae, 72 parts of Zaocyss, 6 parts in Radix Glycyrrhizae, with after concocting pulverizing medicinal materials after be mixed, access strain in the medical material after being mixed, carry out primary fermentation, ferment in second time, fermentation materials is carried out separating and filtering, obtain the sepia fermented liquid, fermented liquid is through sterilization, after the check, fermentation liquid is carried out spray drying, carry out packing with the specification of every bag 15 gram, be up to the standards, namely get this preparation.Choose 60 routine patients with cirrhosis ascites, wherein liver cirrhosis 16 examples account for 26.7%; Initial stage cirrhotic ascites 20 examples account for 33.3%; Late period, hepatic ascites 24 examples accounted for 40.0%; Do 19 examples of western medical treatment, accounted for 31.7%, accepted 34 examples of Chinese traditional treatment, account for 56.7%, do not do 7 examples for the treatment of, and accounted for 11.7%, the patient is all with physical weakness, lethargy, fatigue and weakness, the symptom such as be off one's feed, allow the patient take in this preparation, every day 3 times, each 15 grams, 15 days is 1 course for the treatment of, take continuously 2 courses for the treatment of, contrast before and after taking: take the physical and chemical index that the rear overwhelming majority all shows in various degree and descend, ascites obviously reduces, appetite increases, body constitution strengthens, and complication is improved, and is remarkably productive among the 60 routine patients, feel 28 examples felt quite pleased to account for 46.7%; 24 satisfied examples account for 40.0%; General 8 examples of effect account for 13.3%; Total effective rate 86.7%.
Embodiment two
Select Herba Scirpi Tabernaemontani, the Radix Astragali, Herba Moslae, Fructus Lycii, Herba Houttuyniae, Zaocys, Radix Glycyrrhizae is crude drug, concoct according to selected each component of following parts by weight: 45 parts of Herba Scirpi Tabernaemontanis, 18 parts of the Radixs Astragali, 23 parts of Herba Moslaes, 15 parts of Fructus Lycii, 20 parts of Herba Houttuyniae, 75 parts of Zaocyss, 8 parts in Radix Glycyrrhizae, with after concocting pulverizing medicinal materials after be mixed, access strain in the medical material after being mixed, carry out primary fermentation, ferment in second time, fermentation materials is carried out separating and filtering, obtain the sepia fermented liquid, fermented liquid is through sterilization, after the check, fermentation liquid is carried out spray drying, carry out packing with the specification of every bag 15 gram, be up to the standards, namely get this preparation.Choose 60 routine patients with cirrhosis ascites, wherein liver cirrhosis 16 examples account for 26.7%; Initial stage cirrhotic ascites 20 examples account for 33.3%; Late period, hepatic ascites 24 examples accounted for 40.0%; Do 19 examples of western medical treatment, accounted for 31.7%, accepted 34 examples of Chinese traditional treatment, account for 56.7%, do not do 7 examples for the treatment of, and accounted for 11.7%, the patient is all with physical weakness, lethargy, fatigue and weakness, the symptom such as be off one's feed, allow the patient take in this preparation, every day 3 times, each 15 grams, 15 days is 1 course for the treatment of, take continuously 2 courses for the treatment of, contrast before and after taking: take the physical and chemical index that the rear overwhelming majority all shows in various degree and descend, ascites obviously reduces, appetite increases, body constitution strengthens, and complication is improved, and is remarkably productive among the 60 routine patients, feel 32 examples felt quite pleased to account for 53.3%; 23 satisfied examples account for 38.4%; General 5 examples of effect account for 8.30%; Total effective rate 91.7%.
Embodiment three
Select Herba Scirpi Tabernaemontani, the Radix Astragali, Herba Moslae, Fructus Lycii, Herba Houttuyniae, Zaocys, Radix Glycyrrhizae is crude drug, concoct according to selected each component of following parts by weight: 47 parts of Herba Scirpi Tabernaemontanis, 20 parts of the Radixs Astragali, 24 parts of Herba Moslaes, 17 parts of Fructus Lycii, 22 parts of Herba Houttuyniae, 78 parts of Zaocyss, 10 parts in Radix Glycyrrhizae, with after concocting pulverizing medicinal materials after be mixed, access strain in the medical material after being mixed, carry out primary fermentation, ferment in second time, fermentation materials is carried out separating and filtering, obtain the sepia fermented liquid, fermented liquid is through sterilization, after the check, fermentation liquid is carried out spray drying, carry out packing with the specification of every bag 15 gram, be up to the standards, namely get this preparation.Choose 60 routine patients with cirrhosis ascites, wherein liver cirrhosis 16 examples account for 26.7%; Initial stage cirrhotic ascites 20 examples account for 33.3%; Late period, hepatic ascites 24 examples accounted for 40.0%; Do 19 examples of western medical treatment, accounted for 31.7%, accepted 34 examples of Chinese traditional treatment, account for 56.7%, do not do 7 examples for the treatment of, and accounted for 11.7%, the patient is all with physical weakness, lethargy, fatigue and weakness, the symptom such as be off one's feed, allow the patient take in this preparation, every day 3 times, each 15 grams, 15 days is 1 course for the treatment of, take continuously 2 courses for the treatment of, contrast before and after taking: take the physical and chemical index that the rear overwhelming majority all shows in various degree and descend, ascites obviously reduces, appetite increases, body constitution strengthens, and complication is improved, and is remarkably productive among the 60 routine patients, feel 30 examples felt quite pleased to account for 50.0%; 20 satisfied examples account for 33.4%; General 10 examples of effect account for 16.7%; Total effective rate 83.4%.
The above; it only is preferred forms of the present invention; but protection scope of the present invention is not limited to this; anyly be familiar with those skilled in the art in the technical scope that the present invention discloses; be equal to replacement or change according to technical scheme of the present invention and design thereof, all should be encompassed within protection scope of the present invention.
Claims (2)
1. a pure Chinese medicinal preparation for the treatment of cirrhotic ascites is characterized in that: comprise by weight Herba Scirpi Tabernaemontani 40-50 part, Radix Astragali 15-21 part, Herba Moslae 20-26 part, Fructus Lycii 12-18 part, Herba Houttuyniae 16-24 part, Zaocys 70-80 part, Radix Glycyrrhizae 5-11 part.
2. a kind of pure Chinese medicinal preparation for the treatment of cirrhotic ascites according to claim 1, it is characterized in that: described parts by weight are 45 parts of Herba Scirpi Tabernaemontanis, 18 parts of the Radixs Astragali, 23 parts of Herba Moslaes, 15 parts of Fructus Lycii, 20 parts of Herba Houttuyniae, 75 parts of Zaocyss, 8 parts in Radix Glycyrrhizae.
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| CN106109726A (en) * | 2016-07-29 | 2016-11-16 | 李德全 | A kind of Chinese medicine preparation treating cirrhotic ascites and preparation method |
| CN106729340A (en) * | 2015-11-19 | 2017-05-31 | 哈尔滨圣吉药业股份有限公司 | One farming green onion clearing away heat and eliminating dampeness electuary and preparation method thereof |
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| CN101524435A (en) * | 2009-04-23 | 2009-09-09 | 莫以贤 | Pure natural drug for treating viral hepatitis |
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| CN101524435A (en) * | 2009-04-23 | 2009-09-09 | 莫以贤 | Pure natural drug for treating viral hepatitis |
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| 巴依尔，等: "中医药治疗肝硬化的研究进展", 《中国误诊学杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106729340A (en) * | 2015-11-19 | 2017-05-31 | 哈尔滨圣吉药业股份有限公司 | One farming green onion clearing away heat and eliminating dampeness electuary and preparation method thereof |
| CN106109726A (en) * | 2016-07-29 | 2016-11-16 | 李德全 | A kind of Chinese medicine preparation treating cirrhotic ascites and preparation method |
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