CN102836390A - Weight-reducing medicine for external use - Google Patents
Weight-reducing medicine for external use Download PDFInfo
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- CN102836390A CN102836390A CN2012103381190A CN201210338119A CN102836390A CN 102836390 A CN102836390 A CN 102836390A CN 2012103381190 A CN2012103381190 A CN 2012103381190A CN 201210338119 A CN201210338119 A CN 201210338119A CN 102836390 A CN102836390 A CN 102836390A
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Abstract
The invention provides a weight-reducing medicine for external use and belongs to the field of traditional Chinese medicine. The invention aims to provide the weight-reducing medicine for external use, which has the functions of activating collaterals, reducing lipid, strengthening spleen, removing dampness, prompting circulation and removing stasis so as to reduce weight and lipid. The active component is prepared by the following raw materials in percentage by weight: fructus evodiae, cuttle bone, rhizoma alismatis, root bark of the peony tree, rheum officinale, radix sophorae flavescentis, costustoot, pseudo-ginseng, dragon's blood, endothelium corneum gigeriae galli, rhizoma rinellinae praeparata, dried tangerine or orange peel, hawthorn, and curcuma zedoary. The medicine has the following characteristics of simple preparation, low cost, high treating effect, no toxic or side effect, short treating time, and high social and economic benefits. By adoption of the medicine, the obesity is effectively treated by using Chinese traditional Chinese medicine.
Description
Technical field
The invention belongs to the field of Chinese medicines.
Background technology
Obesity is a body fat, and especially triglyceride (triacylglycerol) gathers a kind of state that too much causes.Change too much owing to food intake usually or organism metabolism causes body fat to gather too much, causes excess weight to increase, and causes the physiological change of human pathology.Worldwide incidence of obesity increases year by year, and WHO has been located and has been a kind of important disease, and it has become public health problem important in the world wide.Obesity can cause hypertension (overweight people's sickness rate is 25～55%), diabetes (overweight people's sickness rate is 14～20%), coronary heart disease (overweight people's sickness rate is 10～15%), hyperlipemia (overweight people's sickness rate is 35～53%), sleep apnea (overweight people's sickness rate is 10～20%), depression (sickness rate is 70～90% among the overweight people) etc., and other also comprises the diseases directly related with life-span and quality of life such as tumor, infertility, calculus.When particularly obesity reaches the pathosis obesity (BMI surpasses 40), its mortality rate can sharply increase, and obesity and relevant disease more and more are much accounted of.
Summary of the invention
The objective of the invention is to adopt theory of Chinese medical science, active blood fat reducing, invigorating spleen to remove dampness, blood circulation promoting and blood stasis dispelling and a kind of weight loss pill for external application of the blood fat reducing of making light of one's life by commiting suicide.
The present invention processes the raw materials of effective components weight portion and consists of:
Fructus Evodiae 50～150 Os Sepiae 50～150 Rhizoma Alismatis 50～150
Cortex Moutan 50～150 Radix Et Rhizoma Rhei 20～100 Radix Sophorae Flavescentiss 20～100
The Radix Aucklandiae 20～100 Radix Notoginseng 50～150 Sanguis Draxonis 20～100
Endothelium Corneum Gigeriae Galli 20～100 Rhizoma Pinelliae Preparatum 50～150 Pericarpium Citri Reticulataes 50～150
Fructus Crataegi 50～150 Rhizoma Curcumae 50～150.
The fat-reducing plaster that the above-mentioned medical material of the present invention is processed, it is processed the raw materials of effective components weight portion and consists of:
Above-mentioned medical material paste 35 medical hot melt type pressure sensitive adhesives 64.85
Azone 0.05 methyl hydroxybenzoate 0.1.
The present invention prepares simply, and is cheap, and good effect has no side effect, and treatment time is short, and is social and good in economic efficiency.Adopted Chinese Chinese medicine efficacious therapy obesity.
The specific embodiment
The present invention processes the raw materials of effective components weight portion and consists of:
Fructus Evodiae 50～150 Os Sepiae 50～150 Rhizoma Alismatis 50～150
Cortex Moutan 50～150 Radix Et Rhizoma Rhei 20～100 Radix Sophorae Flavescentiss 20～100
The Radix Aucklandiae 20～100 Radix Notoginseng 50～150 Sanguis Draxonis 20～100
Endothelium Corneum Gigeriae Galli 20～100 Rhizoma Pinelliae Preparatum 50～150 Pericarpium Citri Reticulataes 50～150
Fructus Crataegi 50～150 Rhizoma Curcumae 50～150.
Get the Chinese crude drug in the present invention's prescription, Sanguis Draxonis powder is broken into fine powder, and is subsequent use; All the other medical materials add 8 times of water gagings and decoct 3 times, and each 1.5 hours, collecting decoction filtered; Filtrating is concentrated into the thick paste of relative density 1.30～1.35 (80 ℃), adds fine powder of dragons blood, and mixing adds other substrate according to the list of ingredients ratio; Mix homogeneously is coated with cream, and cutting promptly gets.
Embodiment 1
The present invention processes the raw materials of effective components weight portion and consists of:
Fructus Evodiae 50 Os Sepiae 50 Rhizoma Alismatis 50
Cortex Moutan 50 Radix Et Rhizoma Rhei 20 Radix Sophorae Flavescentiss 20
The Radix Aucklandiae 20 Radix Notoginseng 50 Sanguis Draxonis 20
Endothelium Corneum Gigeriae Galli 20 Rhizoma Pinelliae Preparatum 50 Pericarpium Citri Reticulataes 50
Fructus Crataegi 50 Rhizoma Curcumae 50.
Get the Chinese crude drug in the present invention's prescription by above-mentioned weight portion, Sanguis Draxonis powder is broken into fine powder, and is subsequent use; All the other medical materials add 8 times of water gagings and decoct 3 times, and each 1.5 hours, collecting decoction filtered; Filtrating is concentrated into the thick paste of relative density 1.30～1.35 (80 ℃), adds fine powder of dragons blood, and mixing adds other substrate according to the list of ingredients ratio; Mix homogeneously is coated with cream, and cutting promptly gets.
Embodiment 2
The present invention processes the raw materials of effective components weight portion and consists of:
Fructus Evodiae 100 Os Sepiae 100 Rhizoma Alismatis 100
Cortex Moutan 100 Radix Et Rhizoma Rhei 50 Radix Sophorae Flavescentiss 50
The Radix Aucklandiae 50 Radix Notoginseng 100 Sanguis Draxonis 50
Endothelium Corneum Gigeriae Galli 50 Rhizoma Pinelliae Preparatum 100 Pericarpium Citri Reticulataes 100
Fructus Crataegi 100 Rhizoma Curcumae 100.
Different except the weight portion of getting ten four Chinese medicines, method for preparing is identical with embodiment 1.
Embodiment 3
The present invention processes the raw materials of effective components weight portion and consists of:
Fructus Evodiae 150 Os Sepiae 150 Rhizoma Alismatis 150
Cortex Moutan 150 Radix Et Rhizoma Rhei 100 Radix Sophorae Flavescentiss 100
The Radix Aucklandiae 100 Radix Notoginseng 150 Sanguis Draxonis 100
Endothelium Corneum Gigeriae Galli 100 Rhizoma Pinelliae Preparatum 150 Pericarpium Citri Reticulataes 150
Fructus Crataegi 150 Rhizoma Curcumae 150.
Different except the weight portion of getting ten four Chinese medicines, method for preparing is identical with embodiment 1.
The fat-reducing plaster that the above-mentioned medical material of the present invention is processed, it is processed the raw materials of effective components weight portion and consists of:
Above-mentioned medical material paste 35 medical hot melt type pressure sensitive adhesives 64.85
Azone 0.05 methyl hydroxybenzoate 0.1.
Wherein above-mentioned medical material paste is the paste that adopts above-mentioned 14 flavor Chinese crude drugs and method for preparing to obtain.
Character of medicinal material
Fructus Evodiae:Dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.Be used for headache, colic, beriberi, dysmenorrhea, abdominal distention, vomiting acid regurgitation, aphtha.
Os Sepiae:Hemostasis, treating spontaneous emission and leukorrhagia, relieving gastric hyperacidity to alleviate stomachache, removing dampness is held back skin ulcer.Cure mainly haematemesis, hematemesis, metrorrhagia is had blood in stool, epistaxis, wound hemorrhage; The emission and spermatorrhea of instability of kidney QI, leucorrhea with red and white discharge; It is noisy to have a stomachache, belch pantothenic acid; Eczema ulcer.
Rhizoma Alismatis:Promoting diuresis to eliminate damp pathogen; It is treating stranguria to expel the heat-evil.Main dysuria; The puckery pain of pyretic stranguria; The edema distension; Have loose bowels; Dizziness due to fluid-retention; Seminal emission.
Cortex Moutan:Clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and pounce on the pain of injury; The rheumatism pyretic arthralgia.
Radix Et Rhizoma Rhei:Purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Be used for the excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire.
Radix Sophorae Flavescentis:Heat clearing and damp drying; Wind dispelling insecticide.Be used for damp-heat dysentery, discharging fresh blood stool, jaundice, dysuria, edema, leukorrhagia, pudendal pruritus, scabies, leprosy, skin pruritus, noxious dampness skin infection.
The Radix Aucklandiae:Promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.Be used for breast gastral cavity distending pain, heavy behind the dysentery, food stagnation does not disappear, anorexia.
Radix Notoginseng:The dissipating blood stasis hemostasis, the effect of subduing swelling and relieving pain.Be used for spitting of blood, spit blood, epistaxis is had blood in stool, metrorrhagia, and traumatic hemorrhage, breast ventral spine pain, tumbling down swells and ache.
Sanguis Draxonis:The dissipating blood stasis analgesic therapy, hemostasia and promoting granulation.Be used for traumatic injury and lose, ecchymoma due to internal injury; Continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time.
Endothelium Corneum Gigeriae Galli:Promoting digestion and invigorating the stomach, arresting seminal emission.Be used for the food stagnation distension, vomiting regurgitation, dysentery, infantile malnutrition is quenched one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.
Rhizoma Pinelliae Preparatum:Drying dampness to eliminate phlegm.Be used for the abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache.
Pericarpium Citri Reticulatae:Regulate the flow of vital energy with in, drying dampness to eliminate phlegm, diuretic relieving constipation.Be used for abdominal distention, anorexia, the vomiting hiccup, cough with copious phlegm, chest and diaphragm is full vexed, the vertigo, edema, dysuria, constipation, acute mastitis scabies, middle fish Eriocheir sinensis poison, alcoholism.
Fructus Crataegi:Appetite-stimulating indigestion-relieving, change stagnant removing food stagnancy, promoting blood circulation to remove blood stasis, the circulation of qi promoting of reducing phlegm.Be used for carnivorous stagnate long-pending, lump in the abdomen, abdominal distention feeling of fullness, the stasis of blood resistance stomachache, phlegm retention, have loose bowels, discharging fresh blood stool etc.
Rhizoma Curcumae: circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For Dan Jia lump, bleeding, amenorrhea, food plot pain.
More than all medicines be monarch drug with the Pericarpium Citri Reticulatae, regulate the flow of vital energy with in, drying dampness to eliminate phlegm, the diuretic relieving constipation is to make light of one's life by commiting suicide; Minister is changed the removing food stagnancy that stagnates with Rhizoma Pinelliae Preparatum, Endothelium Corneum Gigeriae Galli, Fructus Crataegi, Rhizoma Alismatis, the Radix Aucklandiae, Rhizoma Curcumae, invigorating the spleen to clear away damp pathogen, and principal drug assistance strengthens the effect of invigorating the spleen to clear away damp pathogen; Adjuvant drug is Os Sepiae, Cortex Moutan, Radix Et Rhizoma Rhei, Radix Sophorae Flavescentis, Radix Notoginseng, Sanguis Draxonis etc., with the heat clearing away collateral dredging, and the blood stasis dispelling blood fat reducing; With the Fructus Evodiae is messenger drug; Coordinating the actions of various ingredients in a prescription; And can cold expelling supporing yang, all medicine compatibilities, the treatment must aim at the pathogenesis of disease such as obesity card, metabolism syndrome and fatty liver that cause to stagnation of liver-QI with deficiency of the spleen, stagnation of phlegm-damp in middle-JIAO, the hepatic and renal YIN deficiency, the long-pending heat of liver stomach etc.; Reach active blood fat reducing jointly, invigorating spleen to remove dampness, blood circulation promoting and blood stasis dispelling and the therapeutic effect of the blood fat reducing of making light of one's life by commiting suicide.
Organoleptic indicator of the present invention
Table 1 organoleptic indicator
| Project | Index |
| Outward appearance | Faint yellow mastic, color and luster quality are even |
| Abnormal smells from the patient | Special Chinese medicine aromatic odor |
| Impurity | The visible exogenous impurity of no naked eyes |
Physical and chemical index of the present invention
Table 2 physical and chemical index
| Project | Index |
| Net content, g/100cm 2 | 1.5 |
| The net content minus deviation, %<= | 9 |
| Hydrargyrum, mg/Kg<= | 1.0 |
| Plumbous (in Pb), mg/Kg<= | 40.0 |
| Arsenic (in As), mg/Kg<= | 10.0 |
| Cadmium (in Cd), mg/Kg<= | 20.0 |
| Methanol is (with CH 3OH counts), mg/Kg<= | 2000.0 |
| Formaldehyde (in formaldehyde), mg/Kg<= | 75.0 |
Microbiological indicator of the present invention
Table 3 microbiological indicator
| Project | Index |
| Total plate count, cfu/g<= | 20000? |
| Mycete and yeast, cfu/g<= | 500 |
| Excrement colibacillus group | Must not detect |
| Bacillus pyocyaneus | Must not detect |
| Staphylococcus aureus | Must not detect |
| Hemolytic streptococcus | Must not detect |
The present invention is applicable to the overweight crowd who causes because of endocrine disturbance, overnutrition, metabolic syndrome, fatty liver, diabetes, Simple Obesity.Wherein anemia of pregnant woman, women breast-feeding their children, infant, skin injury,, these article allergy sufferers is forbidden.External is forbidden taking orally; If use the back local skin erythema swelling to occur, pruritus should be stopped using immediately, cleans, and seeks advice to the doctor in case of necessity.
Method for using of the present invention: the acupoint selection middle part of gastric cavity, Tianshu, tsu san li, rich and prosperous, cv, get 2～3 caves at every turn, changed in 24～48 hours.
Zoopery:
1. skin acute toxicity test
1.1 material and method:
1.1.1 tried thing: fat-reducing plaster of the present invention, patch, composite membrane is packed.
1.1.2 animal and feeding environment: select 10 of SPF level Wistar rats for use, male and female half and half, body weight 180.0g-220.0g.Animal quality certification SCXK-(Ji) 2011-0004.This laboratory animal environmental facility quality certification: the lucky moving word 10-1005 that establishes, occupancy permit number: SYXK (Ji) 2010-0011,20 ℃-22 ℃ of laboratory animal room temperatures, relative humidity is 55%-65%.1.3.3 test method: press the dosage of 5000mg/kg body weight, the clip sample is attached to back part of animal depilation district (scope 30cm
2～40crn
2), cover with two-layer template, seal fixedly 24h with the nonirritant adhesive plaster, remove behind the 24h and tried thing, observe animal poisoning sign, 7 days observation periods, to weigh once in the 7th day, off-test is put to death animal and is observed general pathology and changes.
1.2 result of the test: after the contamination, the sign of poisoning does not appear in animal, the observation period animal do not have death, general pathology anatomical examination no abnormality seen, LD
50All greater than the 5000mg/kg body weight.
Tried thing to rat acute percutaneous toxicity test result
LD
50: buck is greater than the 5000mg/kg body weight.
Jenny is greater than the 5000mg/kg body weight.
1.3 conclusion: it is nontoxic for reality to the rat skin acute toxicity to be tried thing.
Skin is irritation test repeatedly
2.1 material and method:
1.1.1 tried thing: fat-reducing plaster of the present invention, patch, composite membrane is packed.
2.1.2 animal and feeding environment: select 4 of healthy white big ear rabbits for use, regular grade, animal quality certification SCXK-(Ji) 2007-0004.This laboratory animal environmental facility quality certification: the lucky moving word 10-1005 that establishes, occupancy permit number: SYXK (Ji) 2010-0011,19 ℃ of this laboratory animal room temperatures-2l ℃, relative humidity is 50%-70%.
2.1.3 test method: 24h cuts back part of animal spinal column diamond wool each about 3cm of scope * 3 cm before the test.During test, clip is tried thing and directly is attached to depilation district, right side, area 2.5cm * 2.5cm; Seal fixedly 1h with the nonirritant adhesive plaster, depilation district in left side is contrast, every day 1 time; Continuous 14 days,, tried the preceding cropping of thing from second day Ji beginning at every turn; Remove the residual thing that tried, observed result after a hour with distilled water afterwards.
2.2 result of the test: remove and tried thing after the 6th day, have an animal to be tried position skin and faintly visible erythema successively occurs, average every day, every animal integral mean value was 0.25.
2.3 conclusion: tried thing to rabbit repeatedly skin irritation be nonirritant.
The skin allergic reaction test
3.1 material and method:
3.1.1 tried thing: fat-reducing plaster of the present invention, patch, composite membrane is packed.
3.1.2 positive thing: 2, the 4-dinitrochlorobenzene.
3.1.3 animal and feeding environment: select 40 of healthy albino guinea-pigs for use, regular grade.Animal quality certification SCXK-(Ji) 2007-0004.This laboratory animal environmental facility quality certification: the lucky moving word 10-1005 that establishes, occupancy permit number: SYXK (Ji) 2010-0011,19 ℃-21 ℃ of laboratory animal room temperatures, relative humidity is 50%-70%.
3.1.4 test method: induce contact: clip is tried thing 2cm * 2cm and is attached to depilation district, right side (24h cropping before the test, scope 6cm
2), cover with two layers of gauze, one deck template then, with the sealing of nonirritant adhesive plaster, fixing 6h, the 7th day, the 14 day, repeat once again with quadrat method.Excite contact: last was induced back 14 days, and clip is tried thing 2 ㎝ * 2 ㎝ and is attached to depilation district, animal left side (24h cropping before the test, scope 6 cm
2), then by with quadrat method sealing, fixing 6h.Excite contact back 24h and 48h to observe the left side dermoreaction, and score.
3.2 result of the test: excite contact back 24h, 48h left side skin erythema, edema (seeing attached list) not to occur.
Tried thing to guinea pig skin allergy result of the test (BT method)
The 3-3 conclusion: being tried thing is weak sensitization to guinea pig skin allergy result of the test.
In sum, fat-reducing plaster of the present invention, rat skin acute toxicity test LD
50Greater than 5000mg/kg, belong to actual nontoxic level according to toxicity grading; To rabbit skin repeatedly irritation test be nonirritant; The test of guinea pig skin allergy is weak sensitization.
The auxiliary weight losing function test of fat-reducing plaster of the present invention:
1. material and method
1.1. sample copy invention fat-reducing plaster, approved product is a patch, and composite membrane is packed.Main component is Fructus Evodiae, Os Sepiae, Rhizoma Alismatis, Cortex Moutan, Radix Et Rhizoma Rhei, Radix Sophorae Flavescentis, the Radix Aucklandiae, Radix Notoginseng, Sanguis Draxonis, Endothelium Corneum Gigeriae Galli, Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, Fructus Crataegi, Rhizoma Curcumae etc.
1.2. the obesity crowd that study subject selects simple obesity and hormone to cause, the age is 20～50 years old, the volunteer of constitutional index >=30.Get rid of patient and the psychotic who is associated with diseases such as cardiovascular, cerebrovascular, liver, kidney, hemopoietic system among the experimenter; Eliminating is taken in a short time and is tried the relevant article of function, has influence on the judgement person to the result; Get rid of and to take other associated treatment medicine for a long time or to use other Therapeutic Method, fail termination person; Get rid of the standard of including in that do not meet, by regulation give with, or data is not congruent influences effect or safety judgement person.
1.3. the method for using acupoint selection middle part of gastric cavity, Tianshu, tsu san li, rich and prosperous, cv are got 2～3 caves, change, use continuously 10 days in 24～48 hours at every turn.
1.4. EXPERIMENTAL DESIGN basis " the health product function assessment assessment process and the method for inspection " is middle fat-reducing human trial regulation (DB22-T397-2006); Two kinds of contrast methods of contrast between own control and group before and after the experimenter adopts; Requirement according to the random-blind method is divided into groups, and under the prerequisite of considering influence factors such as subject age, diet, motion, is divided into test group and matched group at random by experimenter's body weight; Every group of experimenter is 20 examples, and carries out the harmony check.Test group is given and given the test agent, and matched group is not handled.To the pairing t-check of test group data before and after experimentizing, two groups of means are relatively adopted t-check in groups.When P < 0.05 the time, thinks that difference has significance.
1.5. key instrument scale, tape measure.
1.6. detect index height, body weight, waistline
1.7. being the SPSS11.5 statistical software, the statistical disposition of all data of statistical method carries out.
2. result
2.1. all complete whole experiment of having participated in of the whole experimenters of test situation does not have seceder midway, does not find to have untoward reaction such as skin allergy.
2.2. body weight and waistline measurement result before and after test group and the matched group test
Body weight and waistline result (
± s) before and after table 1 test group and the matched group test
| Project | Number | A body weight! ㎏) | A waistline! ㎝) |
| Experimental group (preceding) | 20 | 95.8±14.6 | 118.7±14.9 |
| Experimental group (back) | 20 | 88.2±13.7 | 112.6±14.4 |
| Matched group (preceding) | 20 | 96.7±12.0 | 119.9±12.8 |
| Matched group (back) | 20 | 96.6±12.0 | 119.4±12.9 |
L is visible by table, and the body weight of test group and matched group and waistline are relatively more balanced before the test.
2.3 body weight and waistline result and pairing t-assay before and after the test group test
Body weight and waistline result and pairing t-check before and after the test of table 2 test group
Visible by table 2, after test group was given the fat-reducing plaster of the present invention with a course of treatment, decline in various degree all appearred in body weight and waistline, checked difference to have significance (p < 0.01) through pairing t-.
2.4. test group and matched group test back body weight and waistline result reach t-assay in groups
Table 3 test group and matched group test back body weight and waistline result reach t-inspection item in groups
Visible by table 3, test group all occurs decline in various degree with matched group than body weight and waistline after giving the fat-reducing plaster of the present invention with a course of treatment, checks weight loss difference to have significance (P < 0.05) through t-in groups.
In sum, screen 40 routine simple obesity crowds' volunteer, 20 examples are given and this fat-reducing plaster on request, and 20 examples are as blank.After 10 days, before and after the test group self relatively weight loss 7.6kg, the waistline 6.1cm that descended; Has significance (p < 0.01) through self pairing t-check comparing difference; Test group and matched group relatively weight loss 8.4kg, the waistline 6.8cm that descended, in groups the t-check relatively weight loss difference have significance (P < 0.05): other healthy index of correlation of experimenter does not obviously change before and after the test.Judge according to " the health product function assessment is estimated the appearance preface and the method for inspection " criterion in (DB22-T397-2006): fat-reducing plaster of the present invention has auxiliary weight losing function.
Claims (2)
1. weight loss pill for external application is characterized in that: process the raw materials of effective components weight portion and consist of:
Fructus Evodiae 50～150 Os Sepiae 50～150 Rhizoma Alismatis 50～150
Cortex Moutan 50～150 Radix Et Rhizoma Rhei 20～100 Radix Sophorae Flavescentiss 20～100
The Radix Aucklandiae 20～100 Radix Notoginseng 50～150 Sanguis Draxonis 20～100
Endothelium Corneum Gigeriae Galli 20～100 Rhizoma Pinelliae Preparatum 50～150 Pericarpium Citri Reticulataes 50～150
Fructus Crataegi 50～150 Rhizoma Curcumae 50～150.
2. the fat-reducing plaster processed of the said weight loss pill for external application of claim 1 is characterized in that: process the raw materials of effective components weight portion and consist of:
Above-mentioned medical material paste 35 medical hot melt type pressure sensitive adhesives 64.85
Azone 0.05 methyl hydroxybenzoate 0.1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210338119.0A CN102836390B (en) | 2012-09-13 | 2012-09-13 | Weight-reducing medicine for external use |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210338119.0A CN102836390B (en) | 2012-09-13 | 2012-09-13 | Weight-reducing medicine for external use |
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| CN102836390B CN102836390B (en) | 2014-07-02 |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1101842A (en) * | 1993-10-20 | 1995-04-26 | 裴坤苓 | Health oral liquid for weight loss |
| CN1145794A (en) * | 1995-09-20 | 1997-03-26 | 金建文 | Navel applying slimming plaster |
| CN1231900A (en) * | 1998-04-10 | 1999-10-20 | 宋天灵 | Weight-loss medicine and its preparing method |
| CN1363367A (en) * | 2002-01-18 | 2002-08-14 | 北京大学 | Active components of Chinese-medicinal medicine with weight-losing and hypolipemic actions and its relative medicine |
| CN101468147A (en) * | 2007-12-25 | 2009-07-01 | 李亮 | Chinese medicine preparation for reducing fat and lowering lipid |
-
2012
- 2012-09-13 CN CN201210338119.0A patent/CN102836390B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1101842A (en) * | 1993-10-20 | 1995-04-26 | 裴坤苓 | Health oral liquid for weight loss |
| CN1145794A (en) * | 1995-09-20 | 1997-03-26 | 金建文 | Navel applying slimming plaster |
| CN1231900A (en) * | 1998-04-10 | 1999-10-20 | 宋天灵 | Weight-loss medicine and its preparing method |
| CN1363367A (en) * | 2002-01-18 | 2002-08-14 | 北京大学 | Active components of Chinese-medicinal medicine with weight-losing and hypolipemic actions and its relative medicine |
| CN101468147A (en) * | 2007-12-25 | 2009-07-01 | 李亮 | Chinese medicine preparation for reducing fat and lowering lipid |
Non-Patent Citations (3)
| Title |
|---|
| 叶德梁: "化痰祛瘀降脂方治疗高脂血症110例临床观察", 《四川中医》 * |
| 杨福泰等: "调脂健肝汤治疗脂肪肝60例临床观察", 《新中医》 * |
| 黎海彬: "降脂中药的研究进展", 《广州城市职业学院学报》 * |
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| CN102836390B (en) | 2014-07-02 |
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