CN102836221A - Composition containing Armillaria mellea and combination of one or several of Melissa, lavender, chrysanthemum and jasmine - Google Patents

Composition containing Armillaria mellea and combination of one or several of Melissa, lavender, chrysanthemum and jasmine Download PDF

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CN102836221A
CN102836221A CN2012101596732A CN201210159673A CN102836221A CN 102836221 A CN102836221 A CN 102836221A CN 2012101596732 A CN2012101596732 A CN 2012101596732A CN 201210159673 A CN201210159673 A CN 201210159673A CN 102836221 A CN102836221 A CN 102836221A
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radix
semen
flos
flos chrysanthemi
vitamin
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孟令刚
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Abstract

The invention relates to nutritional food and medicines, in particular to a composition, which can clear the brain, relieve uneasiness and adjust the nerves while easing tension headaches, help to improve sleep and have no side effect. The composition comprises 2-98 parts by weight of Armillaria mellea and 2-98 parts by weight of one or several of Melissa, lavender, chrysanthemum and jasmine.

Description

Contain the wherein compositions of one or more combination of Armillaria mellea and Herba Melissae officinalis, lavandula angustifolia, Flos Chrysanthemi, Flos Jasmini Sambac
Technical field
The present invention relates to nutraceutical and medicine, particularly relate to a kind of again can cephalocathartic when effectively alleviating headache calming the nerves, regulating neural, help to improve the compositions of sleeping and having no side effect.
Background technology
Tension-type headache is modern metropolitan cities people's a kind of common " city is sick ".The height of its sickness rate, be headache, approximately city headache patient more than half can be included into the category of tension-type headache.The pressure, tired of work, psychology in addition, is not had enough sleep, mental fatigue, excited, erratic life all can be brought out headache, and musculi colli to be in a certain posture (as bend over one's desk working and learn) for a long time be the main cause that causes tension-type headache.Tension-type headache is psychology and a kind of disease that body common " anxiety " is caused, and consequently can influence sleep and cause the neurasthenia.
The medicine of treatment headache has chemical analgesic, and this type of medicine all is narcotic-based painkillers mostly, is prone to cause habit-forming, and damage Liver and kidney stomach function regulating is prone to side effect such as induced insomnia.The Chinese medicine class is like armillaria mellea accreting with Rhizoma Gastrodiae sheet, medicine containing gastrodia tuber for curing wind syndrome of head etc., and this type of compound preparation effect is slow, influence side effect such as blood pressure and stimulating gastrointestinal, and the Armillaria mellea sheet is slow and do not have a soothing the liver effect of refreshment to the tension headache effect separately.
To sum up, need a kind ofly when effectively alleviating headache, can calm the nerves, regulate nerve, help to improve the product of sleeping and having no side effect by cephalocathartic again.
Summary of the invention
The objective of the invention is to overcome the deficiency of prior art, provide a kind of and when effectively alleviating headache, can calm the nerves, regulate nerve, help to improve sleep and have no side effect by cephalocathartic again, can take for a long time and habit-forming compositions.Said composition is characterised in that and contains wherein one or more of Armillaria mellea and Herba Melissae officinalis, lavandula angustifolia, Flos Chrysanthemi, Flos Jasmini Sambac.Said compositions is dispeled the wind, removing obstruction in the collateral to relieve pain and fragrant cephalocathartic, soothing the liver, resolving depression combine, effectively keeping tensions down headache and can regulate nerve, relieving stress and improvement and sleep.The fragrance of plant can be alleviated people's intense strain, and the alleviating vascular spasm makes people's mood joyful, and stress reduction is improved headache fast, and nervous mood is also effectively alleviated with tired health.
Armillaria mellea
Armillaria is in the genus of Basidiomycetes, Agaricales, fungus, and sporophore is general medium big.Bacteria cover diameter 4-14cm, light khaki, honey color are to fawn.Old back sepia, there is calm or axial ramentum at the middle part, and dipped beam is sliding sometimes, edge tool striped.Suppressing the hyperactive liver relieves dizziness, high fever, infantile convulsions, epilepsy, etc.; Dispelling wind and removing obstruction in the collateral; Bone and muscle strengthening.Main dizzy; Headache; Insomnia; Numb limbs and tense tendons; Lumbago and skelalgia; Coronary heart disease; Hypertension; Vascular headache; Vertiginous syndrome.
Herba Melissae officinalis
Herba Melissae officinalis, this is the cold-resistant plant of a kind of ten minutes, even at sub-zero low temperature, still glossy and green a slice.It is liked by Apis very, and jade-green leaf is very beautiful, rubs the fragrance that can smell one Fructus Citri Limoniae.Like delicate fragrance as the Fructus Citri Limoniae, has magic power and salubrious fragrant and sweet mouthfeel that the brains that can make us and soul become happy.
Lavandula angustifolia
Lavandula angustifolia has another name called the perfume plant, Herba Lysimachiae foenum-graeci, Rhizoma et radix valerianae, Colophonium grass, La Wende.Fragrant refreshment is arranged, alleviate the anxiety effect.
Flos Chrysanthemi
Flos Chrysanthemi, sweet, bitter, be slightly cold, Here it is medicine chrysanthemum can be divided into 4 big types to the medicine chrysanthemum, promptly spends four types of chrysanthemum, Flos Chrysanthemi, Flos Chrysanthemi flower and Flos Chrysanthemi in vain, and Flos Chrysanthemi is returned lung, Liver Channel, and diffusing wind heat clearing away is arranged, and fragrant easing the affected liver, the refreshment effect makes eye bright.
Flos Jasmini Sambac
The present China of Flos Jasmini Sambac kind more than 60 of just having an appointment comprises single-lobe jasmine, bivalve jasmine, many lobes jasmine, and fragrant refreshment, resolving stagnation for tranquilization effect are arranged.
According to the present invention, a kind of compositions is provided, contain: one or more in the Herba Melissae officinalis of the Armillaria mellea of 2-98 weight portion and 2-98 weight portion, lavandula angustifolia, Flos Chrysanthemi, the Flos Jasmini Sambac.Said compositions has the effect of alleviating headache, conditioning emotion and improving sleep.
According to an aspect of the present invention, compositions of the present invention can be applicable to medicine, for example processes pharmaceutically acceptable all solid-state or liquid dosage forms such as tablet, capsule, granule, powder, unguentum, pill, oral liquid and teabag.Said composition realizes that adjuvant that above-mentioned all kinds of dosage form is used and consumption are that dosage form goes up acceptable and meets country adds standard to food adjuvant and consumption.
According to an aspect of the present invention; Compositions of the present invention also can be applicable to food; For example being used for oil is the food on basis, like margarine, mayonnaise, peanut butter, perhaps is used for water sample food; For example fruit drink, sports drink and bland etc.; And add in all kinds of Mel, sugar, various pollen, all kinds of Folium Camelliae sinensis and tea polyphenols, all kinds of nut, fruit and the mixed grain rice, in Semen Juglandis, Semen Sesami, Semen arachidis hypogaeae, Semen Armeniacae Amarum, Semen sojae atricolor, Semen setariae, Semen Phaseoli, Fructus Jujubae, Fructus anacardii, Passifolra edulis, Arillus Longan, Fructus Vitis viniferae, Semen Ziziphi Spinosae etc., process the functional nutrient food that can alleviate headache and improve sleep.
In a specific embodiment, said Armillaria mellea comprises the former raw material of Armillaria mellea, Armillaria mellea extract, its physiologically acceptable salt and derivant thereof.
In a specific embodiment, said Herba Melissae officinalis comprises the former raw material of Herba Melissae officinalis, Herba Melissae officinalis extract, its physiologically acceptable salt and derivant thereof.
In a specific embodiment, the Flos Chrysanthemi of telling comprises spends chrysanthemum, Flos Chrysanthemi, Flos Chrysanthemi flower and Flos Chrysanthemi in vain, comprises the former raw material of its Flos Chrysanthemi, Flos Chrysanthemi extract, its physiologically acceptable salt and derivant thereof.
In a specific embodiment, said lavandula angustifolia comprises the former raw material of lavandula angustifolia, Herba Lysimachiae foenum-graeci extract, its physiologically acceptable salt and derivant thereof.
In a specific embodiment, said Flos Jasmini Sambac comprises the former raw material of Flos Jasmini Sambac, Flos Jasmini Sambac extract, its physiologically acceptable salt, its derivant.
According to a further aspect in the invention, compositions of the present invention also can contain wherein one or more of Fructus Lycii, taurine, Semen Cassiae, Radix Notoginseng, Folium Ginkgo, the Radix Angelicae Dahuricae, the Radix Astragali, Radix Codonopsis or Radix Ginseng or Radix Panacis Quinquefolii, Radix Angelicae Sinensis, Flos Rosae Rugosae, Flos Osmanthi Fragrantis.Fructus Lycii has invigorating the liver and kidney, blood-enriching tranquillizing, the promoting the production of body fluid to quench thirst effect, because of tension headache simultaneously with the hepatic and renal YIN deficiency, deficiency of liver-blood and cause the liver failing to maintain the normal flow of QI is because of the irritability imbalance causes headache, insomnia; Semen Cassiae, Flos Rosae Rugosae and Flos Osmanthi Fragrantis have clearing away liver-fire, clearing away heat and cooling blood, soothing the liver, fragrance is regulated the flow of vital energy and middle effect, can suppress the headache that a heatable brick bed cause on the liver-yang; The effect of invigorating blood circulation of the Radix Angelicae Dahuricae, Radix Notoginseng and Folium Ginkgo, but blood circulation promoting improves anoxia, helps to alleviate headache, improves the blood circulation of sleeping, improving brain, promotes its recovery; The Radix Astragali, Radix Codonopsis or Radix Ginseng or Radix Panacis Quinquefolii and Radix Angelicae Sinensis have the effect of benefiting qi and nourishing blood, can replenish brain nutrition, because of deficiency of qi and blood can cause brain become homeless foster, fatiguability and emotionally disturbed, and cause headache; That taurine has is analgesic, analgesia, nourishing the liver, support the brain effect, but removing heat from blood cephalocathartic, easing the affected liver analgesia.
According to another aspect of the invention, compositions of the present invention also can contain one or more and derivant thereof of multivitamin, trace element, aminoacid, albumen, peptide apoplexy due to endogenous wind.Vitamin comprises: vitamin B1, B2, B12, B6, vitamin C, vitamin E, vitamin AD, folic acid etc.; Trace element comprises: ferrum, zinc, copper, selenium, magnesium etc.; Albumen, aminoacid, peptide class comprise all kinds of animal and vegetable protein and egg albumen, immunoglobulin, metallothionein (MT), dragon protein (fibrin thrombolytic enzyme), ferritin, casein, phycocyanin, nucleic acid, aminoacids complex, aspartic acid, lysine, polypeptide, dipeptides, glutathion, blood pressure lowering peptide.Because of vitimin supplement, trace element and immune protein can improve the nutrition of body and brain, raise immunity helps the recovery of disease.
The present composition is wind and removing obstruction in channels, dispersing the stagnated live-QI to relieve the stagnation of QI, fragrant pain relieving, refreshment but; The cephalocathartic effect is arranged in the pain relieving, calm effect is arranged in the cephalocathartic, cephalocathartic and do not influence sleep; Calm and do not make lethargy; Headache is disappeared in joyful mood, when effectively alleviating headache and pressure, improving sleep quality again, and take for a long time and have no side effect.
The specific embodiment
Embodiment through following further specifies the present invention, yet experimental example of the present invention and embodiment only are used to explain the present invention, should by any way said embodiment be interpreted as the scope of the invention is limited.Unless otherwise indicated, each used composition raw material of the present invention is commercial getting.
The preparation of embodiment 1, the present composition
Utilize the material of listing in the following table to be raw material, uniform mixing can prepare some compositionss of the present invention.It should be understood that the additive-based required adjuvant of available as required prior art processes pharmaceutically acceptable all composition products solid-state or liquid dosage form such as tablet, capsule, granule, powder, cream, ball, oral liquid and teabag.
Instance Raw material
1 2 parts of Armillaria mellea extracts; 98 parts of Herba Melissae officinalis extracts
2 98 parts of Armillaria mellea extracts; 2 parts of Herba Melissae officinalis extracts
3 45 parts of Armillaria mellea extracts; 45 parts of Herba Melissae officinalis extracts
Embodiment 2 present composition keeping tensions down headaches with improve sleep effect experiment
40 routine experimenters are chosen in this experiment, age 28-45 year, women 22 examples; Man's 18 examples are divided into 4 groups at random, and each group is not limit age and sex; Experimental group is 3 groups, every group 10 example, and each group gives the compositions of preparation in the instance 1,2,3 respectively; Dosage is 400mg for each person every day, takes at twice, and test-meal was observed after 10 days; Matched group is 1 group, and number 10 examples are taken single article Armillaria mellea extract, and dosage is 200mg for each person every day, takes at twice, and test-meal was observed after 10 days.Diagnostic criteria: it is that head presents no pulsation dull pain that the case symptom is screened in this experiment, the position on the top, temporo, volume and occipitalia, and with insomnia, the irritated symptom of mood.Criterion of therapeutical effect: carry out the clinical efficacy evaluation with reference to the appeal clinical symptoms.Cure: headache, insomnia, the irritated disappearance; Take a turn for the better: headache, insomnia is alleviated, and agitation alleviates; Invalid: above-mentioned symptom does not have improvement.The result sees table 1.
Table 1 present composition keeping tensions down headache with improve sleep effect experiment
Figure BSA00000720804800041
Figure BSA00000720804800051
The result: of the present invention group of curative effect is superior to matched group.
Other embodiment
Utilize the experiment of other proportionings repetitions embodiment 2 in the scope of the invention, compare with corresponding reference examples, all can obtain identical/similar result (data not shown goes out), compositions of the present invention is effectively alleviated headache, neural, improvement sleep is calmed the nerves, regulated to cephalocathartic.
The present invention only is that example is set forth with the foregoing description, and other proportionings of the concrete proportioning shown in the embodiment and the unshowned present composition all can be used for the present invention and they all can realize technique effect of the present invention.

Claims (10)

1. compositions comprises:
The Armillaria mellea of 2-98 weight portion, and
Wherein one or more of the Herba Melissae officinalis of 2-98 weight portion, lavandula angustifolia, Flos Chrysanthemi, Flos Jasmini Sambac.
2. compositions according to claim 1, wherein said Armillaria mellea comprise the former raw material of Armillaria mellea, Armillaria mellea extract, its physiologically acceptable salt and derivant thereof.
3. compositions according to claim 1, wherein said Herba Melissae officinalis, lavandula angustifolia, Flos Jasmini Sambac comprise its former raw material, its extract, its physiologically acceptable salt and derivant thereof.
4. compositions according to claim 1, the Flos Chrysanthemi of wherein being told comprise spends chrysanthemum, Flos Chrysanthemi, Flos Chrysanthemi flower and Flos Chrysanthemi in vain, comprises the former raw material of its Flos Chrysanthemi, Flos Chrysanthemi extract, its physiologically acceptable salt and derivant thereof.
5. compositions according to claim 1 further comprises wherein one or more of Fructus Lycii, taurine, Semen Cassiae, Radix Notoginseng, Folium Ginkgo, the Radix Angelicae Dahuricae, the Radix Astragali, Radix Codonopsis or Radix Ginseng or Radix Panacis Quinquefolii, Radix Angelicae Sinensis, Flos Rosae Rugosae, Flos Osmanthi Fragrantis.
6. compositions according to claim 1 further comprises one or more of vitamin, trace element, aminoacid, albumen, oryzanol, peptide apoplexy due to endogenous wind.
7. compositions according to claim 6, wherein said vitamin comprises: vitamin B1, B2, B12, B6, vitamin C, vitamin E, vitamin AD, folic acid; Said trace element comprises: ferrum, zinc, copper, selenium, magnesium; Albumen, aminoacid, peptide class comprise all kinds of animal and vegetable protein and egg albumen, immunoglobulin, metallothionein (MT), dragon protein (fibrin thrombolytic enzyme), ferritin, casein, phycocyanin, nucleic acid, aminoacids complex, aspartic acid, lysine, polypeptide, dipeptides, glutathion, blood pressure lowering peptide.
8. compositions according to claim 5, wherein said Fructus Lycii, Semen Cassiae, Radix Notoginseng, Folium Ginkgo, the Radix Angelicae Dahuricae, the Radix Astragali, Radix Codonopsis or Radix Ginseng or Radix Panacis Quinquefolii, Radix Angelicae Sinensis, Flos Rosae Rugosae, Flos Osmanthi Fragrantis can be its primary raw material, its extract, its physiologically acceptable salt and derivant thereof.
9. medicine; Comprise the described compositions of aforementioned arbitrary claim; And pharmaceutically acceptable excipient, said medicine can adopt pharmaceutically acceptable all solid-state or liquid dosage forms such as tablet, capsule, granule, powder, unguentum, pill, oral liquid and teabag.
10. food; Comprise the described compositions of aforementioned arbitrary claim; And acceptable additive on the bromatology; Said food preferably is the food on basis with oil, like margarine, mayonnaise, peanut butter, and perhaps water sample food; For example in fruit drink, tea beverage, sports drink and the bland; Also can add in all kinds of Mel, various pollen, all kinds of Folium Camelliae sinensis or the tea polyphenols and all kinds of nut and dairy products, in Semen Juglandis, Semen Sesami, Semen arachidis hypogaeae, Semen Armeniacae Amarum, Semen sojae atricolor, Semen setariae, Semen Phaseoli, Fructus Jujubae, Fructus anacardii, Passifolra edulis, Arillus Longan, Fructus Vitis viniferae, Semen Ziziphi Spinosae etc., but again can cephalocathartic when processing the keeping tensions down headache calm the nerves, regulate neural and improve the sleep nutraceutical.
CN2012101596732A 2012-05-22 2012-05-22 Composition containing Armillaria mellea and combination of one or several of Melissa, lavender, chrysanthemum and jasmine Pending CN102836221A (en)

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CN103584246A (en) * 2013-11-22 2014-02-19 济南凯因生物科技有限公司 Method for preparing health-care beverage
CN103719660A (en) * 2014-01-06 2014-04-16 威海环翠楼红参科技有限公司 Processing technique of honied Korean red ginseng slices
CN103783606A (en) * 2013-12-20 2014-05-14 芜湖金鹰机械科技开发有限公司 Composite armillaria mellea/sweet potato leaf beverage and preparation method thereof
CN105112193A (en) * 2015-09-01 2015-12-02 陈燕妮 Dry red wine capable of soothing nerves and tonifying brain and brewing method thereof
CN106174487A (en) * 2016-07-11 2016-12-07 安徽济他倍乐生物科技有限公司 A kind of for male for pregnant health food
CN114404576A (en) * 2022-03-31 2022-04-29 深圳德荫堂生物科技有限公司 Medicine for soothing nerves and aiding sleep and production method thereof

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CN102258546A (en) * 2011-04-29 2011-11-30 李光武 Aromatic essential oil type medicament for preventing and treating depression and neurosis, boosting mood and improving brain function and composition thereof

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103584246A (en) * 2013-11-22 2014-02-19 济南凯因生物科技有限公司 Method for preparing health-care beverage
CN103783606A (en) * 2013-12-20 2014-05-14 芜湖金鹰机械科技开发有限公司 Composite armillaria mellea/sweet potato leaf beverage and preparation method thereof
CN103719660A (en) * 2014-01-06 2014-04-16 威海环翠楼红参科技有限公司 Processing technique of honied Korean red ginseng slices
CN105112193A (en) * 2015-09-01 2015-12-02 陈燕妮 Dry red wine capable of soothing nerves and tonifying brain and brewing method thereof
CN106174487A (en) * 2016-07-11 2016-12-07 安徽济他倍乐生物科技有限公司 A kind of for male for pregnant health food
CN114404576A (en) * 2022-03-31 2022-04-29 深圳德荫堂生物科技有限公司 Medicine for soothing nerves and aiding sleep and production method thereof

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Application publication date: 20121226