CN102824567A - Medicinal tea used for treating chloasma and preparation method and application of medicinal tea - Google Patents
Medicinal tea used for treating chloasma and preparation method and application of medicinal tea Download PDFInfo
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- CN102824567A CN102824567A CN2012103463646A CN201210346364A CN102824567A CN 102824567 A CN102824567 A CN 102824567A CN 2012103463646 A CN2012103463646 A CN 2012103463646A CN 201210346364 A CN201210346364 A CN 201210346364A CN 102824567 A CN102824567 A CN 102824567A
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- chloasma
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- medicinal tea
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- 206010008570 Chloasma Diseases 0.000 title claims abstract description 29
- 208000003351 Melanosis Diseases 0.000 title claims abstract description 29
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 235000015091 medicinal tea Nutrition 0.000 title abstract 8
- 239000003814 drug Substances 0.000 claims abstract description 21
- 238000004519 manufacturing process Methods 0.000 claims abstract description 8
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 241001122767 Theaceae Species 0.000 claims description 26
- 241000545442 Radix Species 0.000 claims description 5
- 238000010298 pulverizing process Methods 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 8
- 239000000203 mixture Substances 0.000 abstract description 6
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract description 4
- 230000006870 function Effects 0.000 abstract description 2
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 241001336695 Hedyotis uncinella Species 0.000 abstract 1
- 241001071917 Lithospermum Species 0.000 abstract 1
- 240000003915 Lophatherum gracile Species 0.000 abstract 1
- 102000004316 Oxidoreductases Human genes 0.000 abstract 1
- 108090000854 Oxidoreductases Proteins 0.000 abstract 1
- 240000002322 Pratia nummularia Species 0.000 abstract 1
- 244000269722 Thea sinensis Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 230000000452 restraining effect Effects 0.000 abstract 1
- 235000013616 tea Nutrition 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 6
- 230000007423 decrease Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000010354 integration Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- BDJRBEYXGGNYIS-UHFFFAOYSA-N nonanedioic acid Chemical compound OC(=O)CCCCCCCC(O)=O BDJRBEYXGGNYIS-UHFFFAOYSA-N 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- UIAGMCDKSXEBJQ-IBGZPJMESA-N 3-o-(2-methoxyethyl) 5-o-propan-2-yl (4s)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)[C@H]1C1=CC=CC([N+]([O-])=O)=C1 UIAGMCDKSXEBJQ-IBGZPJMESA-N 0.000 description 1
- 206010003504 Aspiration Diseases 0.000 description 1
- 240000008067 Cucumis sativus Species 0.000 description 1
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000234280 Liliaceae Species 0.000 description 1
- 241000607292 Maguireothamnus speciosus Species 0.000 description 1
- 208000012641 Pigmentation disease Diseases 0.000 description 1
- 102000003425 Tyrosinase Human genes 0.000 description 1
- 108060008724 Tyrosinase Proteins 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000002052 anaphylactic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 229960002255 azelaic acid Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000003518 caustics Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000003255 drug test Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 229960004337 hydroquinone Drugs 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- BEJNERDRQOWKJM-UHFFFAOYSA-N kojic acid Chemical compound OCC1=CC(=O)C(O)=CO1 BEJNERDRQOWKJM-UHFFFAOYSA-N 0.000 description 1
- 229960004705 kojic acid Drugs 0.000 description 1
- WZNJWVWKTVETCG-UHFFFAOYSA-N kojic acid Natural products OC(=O)C(N)CN1C=CC(=O)C(O)=C1 WZNJWVWKTVETCG-UHFFFAOYSA-N 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229960000715 nimodipine Drugs 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229960001727 tretinoin Drugs 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides medicinal tea used for treating chloasma and a preparation method and application of the medicinal tea. The medicinal tea used for treating the chloasma is characterized in that active ingredients contained by the medicinal tea are prepared from the following raw materials in parts by weight: 30-50 parts of angelica sinensis, 20-40 parts of lophatherum gracile, 10-30 parts of lithospermum, 10-30 parts of hedyotis uncinella, 20-40 parts of radix angelicae and 20-40 parts of pratia nummularia. The preparation method comprises the following steps of: drying, crushing, evenly mixing; and bagging to prepare a medicinal tea bag by adopting a conventional tea bag production process. The traditional Chinese medicine composition medicinal tea has functions of restraining the activity of monophenyl oxidase, reducing the generation of melanin, delaying skin ageing and treating the chloasma.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of medicated tea that is used to treat chloasma.
Background technology
Mainly because of the female incretion imbalance, stress is big for chloasma, lacks the stimulation of vitamin and external chemicals in various diseases (hepatic and kidney function obstacle, gynaecopathia, diabetes) etc. and the body and causes.For the chloasma of skin, mainly in line with prevention and the bonded method of treatment.Conditioned female incretion environment keeps happy, and active prevention gynaecopathia etc. is the effective means of prevention chloasma.No special therapeutic method is treated chloasma at present, is divided into methods such as food accent, medication, naturopathy, but can only controls, and can not eradicate chloasma.Local topical medicine commonly used has hydroquinone, Azelaic Acid, tretinoin, kojic acid, chemical cracking-off agent external preparation; But these chemical drugss are easy to generate serious toxic and side effects; Even the intensification chloasma, market in urgent need a kind of effective, oneself is confirmed to treat the chloasma medicated tea by most of people.
Summary of the invention
Goal of the invention:, the object of the present invention is to provide a kind of medicated tea that is used to treat chloasma in order to address the above problem.
Technical scheme: the objective of the invention is to realize through following scheme:
A kind of medicated tea that is used to treat chloasma; Its contained active component is prepared from the following raw materials in part by weight proportioning: Radix Angelicae Sinensis 30-50 part, Herba Lophatheri 20-40 part, Radix Arnebiae (Radix Lithospermi) 10-30 part, to sitting leaf 10-30 part, Radix Angelicae Dahuricae 20-40 part, Herba Pratiae Nummulariae 20-40 part; Through dry, pulverizing; And mix homogeneously, adopting conventional production process of bagged tea again, bagged medicine tea is processed in pack.
The above-mentioned medicated tea that is used to treat chloasma; Its contained active component is prepared from the following raw materials in part by weight proportioning: 40 parts of Radix Angelicae Sinensis, 30 parts of Herba Lophatheris, 20 parts of Radix Arnebiae (Radix Lithospermi)s, to sitting 20 parts on leaf, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Herba Pratiae Nummulariae; Through dry, pulverizing; And mix homogeneously, adopting conventional production process of bagged tea again, bagged medicine tea is processed in pack.
Above-mentioned a kind of medicated tea that is used for treating chloasma is in the application for preparing treatment chloasma medicated tea.
Beneficial effect:
1, the present invention is with Radix Angelicae Sinensis, Herba Lophatheri, Radix Arnebiae (Radix Lithospermi), to sitting leaf, the Radix Angelicae Dahuricae, Herba Pratiae Nummulariae treatment chloasma, the effect that has obvious inhibition melanin to form, and Radix Angelicae Sinensis in the side, Radix Arnebiae (Radix Lithospermi) blood circulation promoting are very effective; The Cucumber Extract cell can be slightly antibacterial to sitting leaf, and antiinflammatory is calm; Make skin clearly comfortable, Herba Lophatheri heat-clearing and toxic substances removing, antibacterial improves the fuel-displaced and inflammation situation of skin; The Radix Angelicae Dahuricae and Herba Pratiae Nummulariae dispel the wind, dampness.Full side uses the merit of playing heat-clearing and toxic substances removing, dispelling speckles and whitening face altogether.But the present invention's restraint of tyrosinase active function, and partial pigmentation is reduced, repair the skin damaged fibers, activation skin tissue cell, delaying decrepitude of skin.We do not contain caustic, and drug safety makes things convenient for, and have good and clinical curative effect and DEVELOPMENT PROSPECT.
2, the present invention writes out a prescription reasonable in designly, and compatibility is rigorous, through secular clinical verification, determined curative effect.
3, the present invention consists of Chinese crude drug, has no side effect low price.
The specific embodiment
Below through the embodiment form; Foregoing of the present invention is remake further detailed description; But should this be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following instance, all technology that realizes based on foregoing of the present invention all belong to scope of the present invention.
1, combine the specific embodiment, the present invention further specified as follows:
Among the present invention to sit leaf be Maguireothamnus speciosus to sitting the dry herb of leaf, Herba Pratiae Nummulariae is the herb that Herba Reineckeae Carneae belongs to the Liliaceae Herba Reineckeae Carneae, all the other are the pharmacopeia kind.
Preparation embodiment: proportioning raw materials is an example in the above table, may further comprise the steps:
Embodiment 1: 30 parts of Radix Angelicae Sinensis, 40 parts of Herba Lophatheris, 10 parts of Radix Arnebiae (Radix Lithospermi)s, to sitting 30 parts on leaf, 20 parts of the Radixs Angelicae Dahuricae, 40 parts of Herba Pratiae Nummulariae, through dry, pulverize, and mix homogeneously adopts conventional production process of bagged tea again, bagged medicine tea is processed in pack.
Embodiment 2: 50 parts of Radix Angelicae Sinensis, 20 parts of Herba Lophatheris, 30 parts of Radix Arnebiae (Radix Lithospermi)s, to sitting 10 parts on leaf, 40 parts of the Radixs Angelicae Dahuricae, 20 parts of Herba Pratiae Nummulariae, through dry, pulverize, and mix homogeneously adopts conventional production process of bagged tea again, bagged medicine tea is processed in pack.
Embodiment 3: 40 parts of Radix Angelicae Sinensis, 30 parts of Herba Lophatheris, 20 parts of Radix Arnebiae (Radix Lithospermi)s, to sitting 20 parts on leaf, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Herba Pratiae Nummulariae, through dry, pulverize, and mix homogeneously adopts conventional production process of bagged tea again, bagged medicine tea is processed in pack.
2. clinical observation material
Sample preparation: press the foregoing description 2 preparation clinical trial samples, specification is the 10g/ bag, and containing the crude drug amount is the 10g/ bag, and the just bright Pharmaceutical Technology Co., Ltd in Nanjing provides.
2.1 physical data: 30 routine patients are in April, 2010～2011 year outpatient service prescription on individual diagnosis in April patient.With reference to " new Chinese medicine clinical research guideline ", include standard in: 1. the age between 18 years old-56 years old, the women.2. do not have infection, not irritated to this medicine, unusual person is a cup too low.Meet the diagnostic criteria (clinical diagnosis of Dermatology Professional Committee of CAIM pigment disease group chloasma and criterion of therapeutical effect (revised draft in 2003)) of chloasma.3. get rid of other dermatosiss and anaphylactic disease:, not allergy sufferers non-stimulated to this medicine.Do not use the similar drug person before the treatment, and do not have and carrying out other similar drug test persons.4. meet the diagnostic criteria of chloasma and include the aspiration patient in the know of standard in; Accomplish informed consent and relevant announcer.
Exclusion standard: 1. do not meet the diagnosis of chloasma and include standard in; Do not meet the standard of including in of chloasma; 2. concurrent infection,, psychological problem irritated to this medicine are arranged.3. judge to have to reduce and go into to organize probability or make according to researcher, often change, cause the situation of visiting of losing easily like working environment into other complicated medical histories of group; Or the experimenter who is participating in the other drug clinical research.
2.2 Therapeutic Method
The treatment of patient with chloasma: soaked taking, 2 bags of every days, inactive other have special efficacy skin care item and medicine during the treatment, and one month is a course of treatment.
2.3 the observation of curative effect criterion of therapeutical effect is with reference to " new Chinese medicine clinical research guideline ".The basic healing: 1. naked eyes are looked the mottle area and are disappeared greater than 90%, and color disappears basically, cannot see tangible speckle apart from naked eyes for 1 meter.2. point system is calculated treatment back decline index >=0.8.Produce effects: 1. naked eyes are looked the mottle area and are disappeared greater than 60%, and color is obviously thin out.2. point system is calculated treatment back decline index >=0.5.Take a turn for the better: 1. naked eyes are looked the mottle area and are disappeared greater than 30%, and color is thin out.2. point system is calculated treatment back decline index >=0.3.Invalid: 1. naked eyes are looked the mottle area and are disappeared less than 30%, and change color is not obvious.2. point system is calculated treatment back decline index >=0.
Computing formula (nimodipine method): [integration before (integration before the treatment-treatment back integration)/treatment] * 100%.
3.3 therapeutic outcome:
30 examples are checked after all finishing 1 course of treatment immediately.Result: cure 3 examples, produce effects 10 examples, effective 12 examples, invalid 5 examples, total effective rate 75%.
Claims (3)
1. medicated tea that is used to treat chloasma; It is characterized in that its contained active component is prepared from the following raw materials in part by weight proportioning: Radix Angelicae Sinensis 30-50 part, Herba Lophatheri 20-40 part, Radix Arnebiae (Radix Lithospermi) 10-30 part, to sitting leaf 10-30 part, Radix Angelicae Dahuricae 20-40 part, Herba Pratiae Nummulariae 20-40 part; Through dry, pulverizing; And mix homogeneously, adopting conventional production process of bagged tea again, bagged medicine tea is processed in pack.
2. the medicated tea that is used to treat chloasma as claimed in claim 1; It is characterized in that its contained active component is prepared from the following raw materials in part by weight proportioning: 40 parts of Radix Angelicae Sinensis, 30 parts of Herba Lophatheris, 20 parts of Radix Arnebiae (Radix Lithospermi)s, to sitting 20 parts on leaf, 30 parts of the Radixs Angelicae Dahuricae, 30 parts of Herba Pratiae Nummulariae; Through dry, pulverizing; And mix homogeneously, adopting conventional production process of bagged tea again, bagged medicine tea is processed in pack.
3. a kind of application of the medicated tea of chloasma that be used for treating as claimed in claim 1 preparation treatment chloasma medicated tea.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210346364.6A CN102824567B (en) | 2012-09-18 | 2012-09-18 | Medicinal tea used for treating chloasma and preparation method and application of medicinal tea |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210346364.6A CN102824567B (en) | 2012-09-18 | 2012-09-18 | Medicinal tea used for treating chloasma and preparation method and application of medicinal tea |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102824567A true CN102824567A (en) | 2012-12-19 |
| CN102824567B CN102824567B (en) | 2014-04-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210346364.6A Expired - Fee Related CN102824567B (en) | 2012-09-18 | 2012-09-18 | Medicinal tea used for treating chloasma and preparation method and application of medicinal tea |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1415338A (en) * | 2002-11-25 | 2003-05-07 | 贵州家诚药业有限责任公司 | medicament for curing diarrhea |
| CN1552367A (en) * | 2003-06-03 | 2004-12-08 | 毛友昌 | Menstruation regulating and face nourishing pills and their preparation |
| CN1765380A (en) * | 2005-09-02 | 2006-05-03 | 北京润德康医药技术有限公司 | Menstruation-regulating face-beautifying Chinese medicinal formulation and its preparation method |
-
2012
- 2012-09-18 CN CN201210346364.6A patent/CN102824567B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1415338A (en) * | 2002-11-25 | 2003-05-07 | 贵州家诚药业有限责任公司 | medicament for curing diarrhea |
| CN1552367A (en) * | 2003-06-03 | 2004-12-08 | 毛友昌 | Menstruation regulating and face nourishing pills and their preparation |
| CN1765380A (en) * | 2005-09-02 | 2006-05-03 | 北京润德康医药技术有限公司 | Menstruation-regulating face-beautifying Chinese medicinal formulation and its preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 杜长明: "艾儒棣论治黄褐斑的经验", 《江苏中医药》 * |
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| CN102824567B (en) | 2014-04-02 |
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