CN102823798A - Maca tablet and preparation method thereof - Google Patents
Maca tablet and preparation method thereof Download PDFInfo
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- CN102823798A CN102823798A CN2012103334999A CN201210333499A CN102823798A CN 102823798 A CN102823798 A CN 102823798A CN 2012103334999 A CN2012103334999 A CN 2012103334999A CN 201210333499 A CN201210333499 A CN 201210333499A CN 102823798 A CN102823798 A CN 102823798A
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Abstract
The invention provides a maca tablet and a preparation method thereof and relates to the technical field of health care products. The maca tablet is prepared by the following raw materials by weight: 581.84 g of maca powder, 56.48 g of microcrystalline cellulose, 30.4 g of lactose, 78.56 g of povidone, 15.12 g of magnesium stearate and 37.6 g of starch; and the average relative molecular weight of the povidone is 2000. The preparation method of the maca tablet comprises the following steps of: uniformly mixing all the raw materials, spraying 90 percent of ethanol solution to moisten, palletizing, drying, carrying out intermediate inspection, granulating and tabletting; and spraying 456.5 g of ethanol solution on every 800 g of raw materials. The maca tablet has the advantages that the effective components are quickly dissolved out, the biological availability is high, and the medical effects of effective component maca can be better realized, and the cost for drug consumption is reduced. The maca tablet has the effects of relieving the physical fatigue, improving the sexual function, improving the fertility, adjusting the internal secretion and the like, and particularly relieving the physical fatigue and the improving the sexual function.
Description
Technical field
The present invention relates to health product technology field, particularly a kind of agate coffee sheet also relates to the preparation method of said agate coffee sheet.
Background technology
Agate coffee (MACA), rhizome are as the turnip radish head, and leaf is prone to survival as the carrot seedling.This kind of plant mainly is grown in the area, plateau, Andes of more than 4000 meter of Peru's middle part height above sea level, and high and cold, the high wind in there, ecological environment are very abominable, are not suitable for other plant growth.
The agate coffee was both pharmaceutically acceptable, and also edible is nutritious because of it, was to live in one of incaic main food source in highlands always over thousands of years, thereby received incaic favor.Before 500 years, the agate coffee strengthens, and medical value physical, that raise libido just extensively uses in Peru.Such legend is arranged: in Inca Theocracy period, will eat the agate coffee before the soldier goes to the front, can make their strength multiplication afield, fight the enemy bravely because eaten the agate coffee.
For many years, international medical community never stopped the research to the agate coffee, and nearest a series of discovering, the agate anti-fatigue effect is fabulous, and the health of not overdrawing, and was without any side effects.Its root has special gene, just makes it have the effect of this mystery.The eighties in 20th century, plantation agate coffee was once recommended to countries in the world by FAO (Food and Agriculture Organization of the United Nation).In the U.S., Japan and European, the expert recommends edible agate coffee to the sportsman, to help their fast quick-recovery physical efficiency.
Nowadays, Along with people's is to the research of the agate coffee property of medicine, and the agate coffee is accepted by increasing people.In order to satisfy people's demand, Peru every year is all in the plantation amount that increases the agate coffee.At present, about about 400 tons, the agate coffee has become one of these state main exit industrial crops to the agate coffee output of Peru greatly.
Present society, rhythm of life is fast, and operating pressure is big, is easy to cause tired sensation, and in the market in the health food of antifatigue, is broadly divided into following several types:
1, makeup energy usually reaches and keeps the body normal physiological function, the purpose of relieving fatigue through replenishing the nutrition that is consumed in the motion;
2, replenish the vitamin and the trace element of needed by human body;
3, the function of the function, the particularly circulatory system through improving the volume organ, removing, the eliminating of acceleration bodies intracellular metabolite material reach the purpose of antifatigue, and a lot of Chinese herbal and crude drugs preparationses all belong to this type.
But fatigue takes place that composite factor often causes, and each link closely links to each other, and only is that to come antifatigue to some alleviations wherein be incomplete.
Tablet is meant medicinal substances extract, medicinal substances extract are added the disk shape that medicinal material fine powder or medicinal material fine powder and the compacting of proper auxiliary materials mixing form or the preparation of special-shaped sheet.Its advantage is: the dissolution rate and the bioavilability of tablet are better usually; Dosage is accurate, and medicament contg difference is less in the tablet; Steady quality, tablet are drying solid, and some easy oxidation deterioration and deliquescent medicine can borrow dressing protect, and light, air, moisture etc. are less to its influence; Take, carry, transportation etc. is more convenient; Mechanization is produced, and output is big, and cost is low, and sanitary standard reaches easily.
Though agate coffee sheet Related product is also arranged on the market, like mountain balsam peak board agate coffee sheet, its active ingredient stripping is slow, bioavilability is low, greatly reduces the product utilization rate, has improved virtually and has taken cost.
Summary of the invention
In order to solve the problem that the stripping of above existing agate coffee sheet active ingredient is slow, bioavilability is low, the invention provides the agate coffee sheet that a kind of active ingredient stripping is fast, bioavilability is high.
The present invention also provides the preparation method of said agate coffee sheet.
The present invention realizes through following measure:
A kind of agate coffee sheet, process by following materials of weight proportions:
Pueraria root powder 581.84g, microcrystalline cellulose 56.48g, lactose 30.4g, PVP 78.56g, dolomol 15.12g, starch 37.6g;
The average weight-molecular mass of said PVP is 2000.
The preparation method of described agate coffee sheet mixes each raw material, sprays 90% ethanolic solution and makes it moistening, granulates oven dry, intermediate survey, whole grain, compressing tablet;
Every 800g raw material spray 456.5g ethanolic solution.
Process the tablet that specification is the 0.8g/ sheet.
Pueraria root powder is a raw material with the agate coffee, processes through steps such as section, drying, pulverizing, sterilizations, is ratified as new resource food by the Ministry of Public Health.It is unique and abundant to human health, procreation, to plant chemical ingredient and bioactivator anti-ageing, that life power is provided that the agate coffee is had, for the agate coffee provides scientific basis to the mankind's health-care efficacy and pharmacological action.Collection scientist's's decades achievement in research is found that the agate coffee contains multiple alkaloid activity composition, meson oil glycosides, sterol, several amino acids and health is played the active secondary metabolites of special physiological function.
Fresh agate coffee (MACA) contains moisture 10.4%, protein 10.2%, fat 2.2%, carbohydrate 59%, fiber 8.5%, ash content 4.9%.The amino acid that contains abundant needed by human, as: arginine (9.94%), asparatate (9.17%), glutamic acid (15.6%) and lysine (54.5%) etc.The content of unrighted acid accounts for 52.7% (wherein linoleic acid 18.5%, leukotrienes 8.81%) in the aliphatic acid of agate coffee (MACA), contains glucosinolate sterol and potassium, calcium, iron etc.Agate coffee alkene and agate coffee acid amides are contained in agate coffee (MACA) lipid position; Also comprise N-benzyl caprylamide, N-benzyl-16-hydroxyl-9-oxidation-10E; 12E, the hot certain herbaceous plants with big flowers triolefin of 14E-acid amides, N-benzyl-16-hydroxyl-9,16-dioxy-10E; 12E, the homologue of the hot certain herbaceous plants with big flowers triolefin acid amides of 14E-and other 17 agate coffee alkene and agate coffee acid amides.Agate coffee alkene and agate coffee acid amides are considered to have one of active principle that promotes sexual function in agate coffee (MACA) extract.
Beneficial effect of the present invention: agate coffee sheet of the present invention, the active ingredient stripping is fast, bioavilability is high, can better bring into play the drug effect of active ingredient agate coffee, reduces drug cost.Effect of the present invention comprises alleviating physical fatigue, improves sexual function, improves fecundity, regulates endocrine etc., especially with alleviating physical fatigue with to improve the sexual function effect best.
The specific embodiment
For a better understanding of the present invention, further specify below in conjunction with specific embodiment.
Embodiment:
A kind of agate coffee sheet, process by following materials of weight proportions:
Pueraria root powder 581.84g, microcrystalline cellulose 56.48g, lactose 30.4g, PVP 78.56g, dolomol 15.12g, starch 37.6g;
The average weight-molecular mass of PVP is 2000.
Preparation method: each raw material is mixed, spray 90% ethanolic solution and make it moistening, granulate, oven dry, intermediate survey, whole grain, compressing tablet; Every 800g raw material spray 456.5g ethanolic solution is processed the tablet that specification is the 0.8g/ sheet.
Usage and dosage: these article are tablet, suitable swallowing.Every day 2 times, each 2-3 sheet.
The dissolution velocity experiment:
These article use the hanging basket method to measure.
Measure the purified water 900ml that handles through the degassing, inject in each process container, heating makes solvent temperature remain on 37 ± 0.5 ℃, and the adjustment rotating speed makes it stable.Getting the test sample input changes in the basket, will change basket and fall in the container, picks up counting immediately; During to 1 minute, 5 minutes, 15 minutes, 30 minutes and 45 minutes; An amount of in regulation sample point draw solution respectively, filter through 0.8 μ m miillpore filter immediately, being sampled to filtration certainly should accomplish in 30 seconds.Get filtrating, measure trap at the 500nm place, measure result such as following table through ultraviolet-visible spectrophotometry:
Use and observe:
(1) Lee, the man, 50 years old, fatiguability, nose heave, drowsiness, unable.Take the agate coffee sheet that the embodiment of the invention 1 makes, every day sooner or later each once, each 3, took continuously 15 days, fatigue symptom alleviates, the state of mind is obviously improved.
(2) Lee, the man, 42 years old, soreness and weakness of waist and knees, unable, melancholy, agitation and emotional lability, interruptions of sleep.Take the agate coffee sheet that the embodiment of the invention 2 makes, every day sooner or later each once, each 2, took continuously 20 days, sleep quality obviously improves, irritated, melancholy mood is obviously improved, the soreness and weakness of waist and knees phenomenon has not existed.
Zhang, the man, 35 years old, poor appetite, anxiety, absent minded, idol has the premature ejaculation phenomenon.Take the agate coffee sheet that the embodiment of the invention 1 makes, every day sooner or later each once, each 2, took continuously 10 days, the premature ejaculation phenomenon is improved obviously, the state of mind is good.
Claims (3)
1. agate coffee sheet is characterized in that being processed by following materials of weight proportions:
Pueraria root powder 581.84g, microcrystalline cellulose 56.48g, lactose 30.4g, PVP 78.56g, dolomol 15.12g, starch 37.6g;
The average weight-molecular mass of said PVP is 2000.
2. the preparation method of the described agate coffee of claim 1 sheet is characterized in that each raw material is mixed, and sprays 90% ethanolic solution and makes it moistening, granulates oven dry, intermediate survey, whole grain, compressing tablet;
Every 800g raw material spray 456.5g ethanolic solution.
3. preparation method according to claim 2 is characterized in that processing the tablet that specification is the 0.8g/ sheet.
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| CN2012103334999A CN102823798A (en) | 2012-09-11 | 2012-09-11 | Maca tablet and preparation method thereof |
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| CN2012103334999A CN102823798A (en) | 2012-09-11 | 2012-09-11 | Maca tablet and preparation method thereof |
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| CN102823798A true CN102823798A (en) | 2012-12-19 |
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Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039791A (en) * | 2012-12-31 | 2013-04-17 | 天津北洋百川生物技术有限公司 | Pressed candy with functions of adjusting and improving human endocrine system and preparation method thereof |
| CN103211136A (en) * | 2013-01-05 | 2013-07-24 | 湖北不老坊食品有限责任公司 | Maca bee milk tablets |
| CN103238842A (en) * | 2013-05-21 | 2013-08-14 | 天津兰瑞生物技术有限公司 | Limulus egg and maca health-care tablets and preparation method thereof |
| CN103494303A (en) * | 2013-10-21 | 2014-01-08 | 新疆善好食品有限公司 | Maca powder solid drink and producing method |
| CN103622020A (en) * | 2013-12-03 | 2014-03-12 | 江苏江大源生态生物科技有限公司 | Rape bee-pollen and Maca powder health-care tablet and preparation method thereof |
| CN103652927A (en) * | 2013-12-30 | 2014-03-26 | 重庆喜旋生物科技有限公司 | Dispersible tablet of maca, preparation method and application thereof |
| CN103734446A (en) * | 2014-01-22 | 2014-04-23 | 丁圣权 | Maca-containing tabletted candy and production method thereof |
| CN104013716A (en) * | 2014-05-20 | 2014-09-03 | 绿健园（新乡）生物工程有限公司 | Maca tablet |
| CN104382045A (en) * | 2014-11-27 | 2015-03-04 | 福州缘顺食品有限公司 | Lepidium meyenii walp chewable tablets and preparation method thereof |
| CN104397719A (en) * | 2014-11-19 | 2015-03-11 | 苏州俞氏药业有限公司 | Maca tablet and preparation method thereof |
| CN104397302A (en) * | 2014-11-05 | 2015-03-11 | 云南泽杰生物科技有限公司 | Compressed tablet candy containing Maca and ginseng |
| CN104605462A (en) * | 2015-01-28 | 2015-05-13 | 广西日田药业集团有限责任公司 | Preparation method of Maca tea effervescent tablets |
| CN104687048A (en) * | 2015-03-09 | 2015-06-10 | 江苏慧博生物科技有限公司 | Maca tablet and preparation method thereof |
| CN105054041A (en) * | 2015-09-02 | 2015-11-18 | 上海悦萌环保科技有限公司 | Fatigue preventing maca tablet |
| CN105211859A (en) * | 2015-10-13 | 2016-01-06 | 杭州艺福堂茶业有限公司 | A kind of agate coffee wheat seeding oral tablet and preparation method thereof |
| CN111686157A (en) * | 2019-03-15 | 2020-09-22 | 江苏康缘药业股份有限公司 | Composition with function of improving immunity and preparation method thereof |
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Cited By (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039791B (en) * | 2012-12-31 | 2014-02-26 | 天津北洋百川生物技术有限公司 | Pressed candy with functions of adjusting and improving human endocrine system and preparation method thereof |
| CN103039791A (en) * | 2012-12-31 | 2013-04-17 | 天津北洋百川生物技术有限公司 | Pressed candy with functions of adjusting and improving human endocrine system and preparation method thereof |
| CN103211136A (en) * | 2013-01-05 | 2013-07-24 | 湖北不老坊食品有限责任公司 | Maca bee milk tablets |
| CN103238842A (en) * | 2013-05-21 | 2013-08-14 | 天津兰瑞生物技术有限公司 | Limulus egg and maca health-care tablets and preparation method thereof |
| CN103494303A (en) * | 2013-10-21 | 2014-01-08 | 新疆善好食品有限公司 | Maca powder solid drink and producing method |
| CN103622020A (en) * | 2013-12-03 | 2014-03-12 | 江苏江大源生态生物科技有限公司 | Rape bee-pollen and Maca powder health-care tablet and preparation method thereof |
| CN103652927B (en) * | 2013-12-30 | 2015-12-09 | 重庆喜旋生物科技有限公司 | A kind of agate coffee dispersing tablet and preparation method thereof and application |
| CN103652927A (en) * | 2013-12-30 | 2014-03-26 | 重庆喜旋生物科技有限公司 | Dispersible tablet of maca, preparation method and application thereof |
| CN103734446A (en) * | 2014-01-22 | 2014-04-23 | 丁圣权 | Maca-containing tabletted candy and production method thereof |
| CN104013716A (en) * | 2014-05-20 | 2014-09-03 | 绿健园（新乡）生物工程有限公司 | Maca tablet |
| CN104397302A (en) * | 2014-11-05 | 2015-03-11 | 云南泽杰生物科技有限公司 | Compressed tablet candy containing Maca and ginseng |
| CN104397719A (en) * | 2014-11-19 | 2015-03-11 | 苏州俞氏药业有限公司 | Maca tablet and preparation method thereof |
| CN104382045A (en) * | 2014-11-27 | 2015-03-04 | 福州缘顺食品有限公司 | Lepidium meyenii walp chewable tablets and preparation method thereof |
| CN104605462A (en) * | 2015-01-28 | 2015-05-13 | 广西日田药业集团有限责任公司 | Preparation method of Maca tea effervescent tablets |
| CN104687048A (en) * | 2015-03-09 | 2015-06-10 | 江苏慧博生物科技有限公司 | Maca tablet and preparation method thereof |
| CN104687048B (en) * | 2015-03-09 | 2017-04-19 | 西安交通大学医学院第一附属医院 | Maca tablet and preparation method thereof |
| CN105054041A (en) * | 2015-09-02 | 2015-11-18 | 上海悦萌环保科技有限公司 | Fatigue preventing maca tablet |
| CN105211859A (en) * | 2015-10-13 | 2016-01-06 | 杭州艺福堂茶业有限公司 | A kind of agate coffee wheat seeding oral tablet and preparation method thereof |
| CN111686157A (en) * | 2019-03-15 | 2020-09-22 | 江苏康缘药业股份有限公司 | Composition with function of improving immunity and preparation method thereof |
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Application publication date: 20121219 |