CN102823511A - Device for testing activity of animals under tail suspension state - Google Patents

Device for testing activity of animals under tail suspension state Download PDF

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Publication number
CN102823511A
CN102823511A CN2011101613771A CN201110161377A CN102823511A CN 102823511 A CN102823511 A CN 102823511A CN 2011101613771 A CN2011101613771 A CN 2011101613771A CN 201110161377 A CN201110161377 A CN 201110161377A CN 102823511 A CN102823511 A CN 102823511A
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CN
China
Prior art keywords
test
crossbeam
testing
casing
transmission box
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011101613771A
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Chinese (zh)
Inventor
刘新民
李海清
李翊华
孙秀萍
殷泰晖
李腾飞
石哲
付建国
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Xinhaihuayi Technology Co ltd
Weimingtianren Chinese Medicine Co ltd
Institute of Medicinal Plant Development of CAMS and PUMC
Original Assignee
Beijing Xinhaihuayi Technology Co ltd
Weimingtianren Chinese Medicine Co ltd
Institute of Medicinal Plant Development of CAMS and PUMC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Xinhaihuayi Technology Co ltd, Weimingtianren Chinese Medicine Co ltd, Institute of Medicinal Plant Development of CAMS and PUMC filed Critical Beijing Xinhaihuayi Technology Co ltd
Priority to CN2011101613771A priority Critical patent/CN102823511A/en
Publication of CN102823511A publication Critical patent/CN102823511A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a device for testing activity of animals under the tail suspension state. The device comprises an uncovered testing box body, a sealed collecting and transmitting box and a computer operation system which are connected in turn, wherein the inner part of the testing box body is divided into eight testing lattices capable of partitioning small animals by partition plates; a beam is arranged above the testing box body by a supporting rod which is fixed on the testing box body; eight sensors are fixed on both sides of the beam by sensor fixing rods and correspond to the positions of the testing lattices below; and a plurality of hooks are connected below the sensors. The device provided by the invention for testing activity of the animals under the tail suspension state is reasonable in design and compact in structure, and meets the needs of each animal suspension test.

Description

Be used for movable device under the outstanding shape of tail attitude of test animal
Technical field
The present invention relates to a kind of zoopery equipment, particularly a kind of movable device under the outstanding shape of tail attitude of test animal that is used for that is applied to the animal suspended experiment.
Background technology
The outstanding tail test of animal is meant in official hour; The dead time of monitoring, record and analyzing animal and struggle intensity; Be a kind of common experimental method of judging the desperate state of animal behavior, be worth having important use aspect the model evaluation of neural psychotic disorders such as depression and the evaluating drug effect.
The movable experimental technique of the outstanding tail of monitor animal has three kinds usually both at home and abroad at present.One of which is the video tracking technology, obtains the information such as dead time of animal under outstanding shape of tail attitude through the shooting mode.This technology no doubt provides display interface more intuitively, but its tracking error can not be ignored, and especially laboratory animal increases to more than 2, and the inaccuracy of video tracking is more outstanding.It two is the infrared thermal release electric principle, and this principle is subject to the influence of ambient temperature and animal movement state, and ambient temperature is crossed low or animal movement when slow, the erroneous judgement phenomenon often occurs, causes the result inaccurate.It three is Fundamentals of Sensors, and this principle has higher sensitivity and accuracy, compares with video tracking and pyroelectricity principle, uniquely can carry out quantitative analysis to animal struggle intensity through merit and power.Native system except that possessing the above characteristic, through regulating the crossbeam height, can accomplish that 8 animals hang simultaneously based on Fundamentals of Sensors, saves manpower, reduces operate miss.Simultaneously, sealing around outstanding tail testing cassete adopts, the open form of end face had both been avoided environmental interference, can gather available light again.Testing cassete integrated two rows arrange, and is compact to design, saves the space.
Summary of the invention
To the objective of the invention is in order addressing the above problem, to have designed a kind of movable device under the outstanding shape of tail attitude of test animal that is used for.
Realize that above-mentioned purpose technical scheme of the present invention does; A kind of device that is used for activity under the outstanding shape of tail attitude of test animal; Collection transmission box and a computer operating system of comprising the test casing of a uncovered, a sealing; The test casing of uncovered, the collection transmission box of sealing are connected with computer operating system successively, wherein test box house and are separated into eight the test lattice that can isolate small animal with dividing plate, and crossbeam is installed in the top of testing casing through the support bar that is fixed on the test casing; Eight sensors through the sensor dead lever be fixed in the crossbeam both sides and with following test case put corresponding, sensor below coupling hook.
More excellent, said crossbeam is connected with support bar through positioning sliding block, just can move up and down crossbeam through regulating positioning sliding block.
More excellent, the bottom of said test casing is removable collecting dung plate.
More excellent, said collection transmission box inside comprises signal adjustment circuit, Acquisition Circuit and output circuit.
More excellent, on the said crossbeam socket being installed, the test casing is connected with the collection transmission box through socket
The present invention compared with prior art has following beneficial effect: the present invention can accomplish that eight animals hang simultaneously through regulating the crossbeam height.When the crossbeam height reduced, the animal tail end was fixed in hook, and fore paw lands, and rear solid end is unsettled, is half suspension status; Regulating handle raises crossbeam, and animal then is complete suspension status, thereby accomplishes that eight animals hang simultaneously, saves manpower, reduces operate miss.The test lattice around the sealing, avoid environmental interference, avoid to greatest extent various burst factors to the experiment due to interference; End face is open simultaneously, can gather available light, simulating natural environment; Testing cassete integrated two rows arrange, and is compact to design, saves the space.
Description of drawings
Fig. 1 is the structural representation that is used for device movable under the outstanding shape of tail attitude of test animal according to the invention;
Among the figure, 1, the test casing; 2, gather transmission box; 3, computer operating system; 4, dividing plate; 5, test lattice; 6, crossbeam; 7, support bar; 8, sensor; 9, sensor dead lever; 10, hook; 11, positioning sliding block; 12, collecting dung plate; 13, adjustment circuit; 14, Acquisition Circuit; 15, output circuit; 16, socket.
Embodiment
For ease of the understanding of technical scheme of the present invention, introduce below in conjunction with concrete embodiment.As shown in Figure 1; A kind of device that is used for activity under the outstanding shape of tail attitude of test animal; Comprise the test casing 1 of a uncovered, collection transmission box 2 and computer operating system 3 of a sealing; The test casing of uncovered, the collection transmission box of sealing are connected with computer operating system successively, wherein test box house and are separated into eight the test lattice 5 that can isolate small animal with dividing plate 4, and crossbeam 6 is installed in the top of testing casing through the support bar 7 that is fixed on the test casing; Eight sensors 8 are fixed in the crossbeam both sides and put corresponding with following test case through sensor dead lever 9; Sensor below coupling hook 10, and said crossbeam is connected with support bar through positioning sliding block 11, just can move up and down crossbeam through regulating positioning sliding block; The bottom of said test casing is removable collecting dung plate 12; Said collection transmission box inside comprises signal adjustment circuit 13, Acquisition Circuit 14 and output circuit 15; Socket 16 is installed on the said crossbeam, and the test casing is connected with the collection transmission box through socket.
With reference to figure 1, in embodiments of the present invention, eight test lattice of placing small animal become two rows also together.Test lattice open-top, sealing all around, the legacy the when bottom is convenient to clear up zoopery for the collecting dung plate.Eight sensors are fixed on the crossbeam through the sensor dead lever, and crossbeam is fixed on the support bar through positioning sliding block moving up and down.The further reinforcing crossmember of dead lever.Testing cassete links to each other with the collection transmission box through the connecting line that assigns on the socket.
With reference to figure 2, computer operating system links to each other with the collection transmission box through connecting line.
Computer operating system comprises: main control computer, be installed in outstanding tail experiment software and printer on the main control computer, main control computer is installed outstanding tail software; Said outstanding tail experiment software is provided with outstanding tail experiment model and various experiment parameter; Signal with reception of control main control computer and processing; The active state of animal in test box estimated, record, statistics, demonstration, preservation experimental data, and directly drive the printer prints laboratory report.
Technique scheme has only embodied the optimal technical scheme of technical scheme of the present invention, the technical staff in present technique field to some part wherein some changes that possibly make all embodied principle of the present invention, belong within the protection domain of invention.

Claims (5)

1. one kind is used for movable device under the outstanding shape of tail attitude of test animal; The collection transmission box (2) and the computer operating system (3) that comprise the test casing (1) of a uncovered, a sealing; The test casing of uncovered, the collection transmission box of sealing are connected with computer operating system successively; It is characterized in that the test box house is separated into eight the test lattice (5) that can isolate small animal with dividing plate (4), crossbeam (6) is installed in the top of testing casing through the support bar (7) that is fixed on the test casing; Eight sensors (8) through sensor dead lever (9) be fixed in the crossbeam both sides and with following test case put corresponding, sensor below coupling hook (10).
2. the device that is used for activity under the outstanding shape of tail attitude of test animal according to claim 1 is characterized in that crossbeam is connected with support bar through positioning sliding block (11), just can move up and down crossbeam through regulating positioning sliding block.
3. the device that is used for activity under the outstanding shape of tail attitude of test animal according to claim 1 is characterized in that the bottom of test casing is a removable collecting dung plate (12).
4. the device that is used for activity under the outstanding shape of tail attitude of test animal according to claim 1 is characterized in that, gathers transmission box inside and comprises signal adjustment circuit (13), Acquisition Circuit (14) and output circuit (15).
5. the device that is used for activity under the outstanding shape of tail attitude of test animal according to claim 1 is characterized in that, socket (16) is installed on the said crossbeam, and the test casing is connected with the collection transmission box through socket.
CN2011101613771A 2011-06-16 2011-06-16 Device for testing activity of animals under tail suspension state Pending CN102823511A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011101613771A CN102823511A (en) 2011-06-16 2011-06-16 Device for testing activity of animals under tail suspension state

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2011101613771A CN102823511A (en) 2011-06-16 2011-06-16 Device for testing activity of animals under tail suspension state

Publications (1)

Publication Number Publication Date
CN102823511A true CN102823511A (en) 2012-12-19

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CN2011101613771A Pending CN102823511A (en) 2011-06-16 2011-06-16 Device for testing activity of animals under tail suspension state

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104138265A (en) * 2013-05-08 2014-11-12 上海交通大学医学院 Device for preventing climbing on tail in animal tail suspension test
CN111903607A (en) * 2020-08-11 2020-11-10 安徽正华生物仪器设备有限公司 Automatic analysis system and method based on deep learning rodent tail suspension experiment

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3897751A (en) * 1974-07-10 1975-08-05 Us Health Cage for continuous infusion
EP0214169A1 (en) * 1985-02-26 1987-03-18 Lucien Steru Method and device for evaluating the psychotropic effects of medicinal substances on animals.
US6279511B1 (en) * 1998-10-23 2001-08-28 Instech Laboratories, Inc. Powered multichannel infusion and monitoring system
US20040143414A1 (en) * 2003-01-17 2004-07-22 Taipei Veterans General Hospital Tail suspension test apparatus
EP0986951B1 (en) * 1998-09-18 2008-09-03 Bioanalytical Systems, Inc Movement-responsive system for conducting tests on freely-moving animals
CN201239203Y (en) * 2008-07-24 2009-05-20 余震 Tail suspension tester
CN201542752U (en) * 2009-12-15 2010-08-11 双卫兵 Experimental facility used for preparing spinal cord injury animal model

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3897751A (en) * 1974-07-10 1975-08-05 Us Health Cage for continuous infusion
EP0214169A1 (en) * 1985-02-26 1987-03-18 Lucien Steru Method and device for evaluating the psychotropic effects of medicinal substances on animals.
EP0214169B1 (en) * 1985-02-26 1991-07-24 STERU, Lucien Method and device for evaluating the psychotropic effects of medicinal substances on animals
EP0986951B1 (en) * 1998-09-18 2008-09-03 Bioanalytical Systems, Inc Movement-responsive system for conducting tests on freely-moving animals
US6279511B1 (en) * 1998-10-23 2001-08-28 Instech Laboratories, Inc. Powered multichannel infusion and monitoring system
US20040143414A1 (en) * 2003-01-17 2004-07-22 Taipei Veterans General Hospital Tail suspension test apparatus
CN201239203Y (en) * 2008-07-24 2009-05-20 余震 Tail suspension tester
CN201542752U (en) * 2009-12-15 2010-08-11 双卫兵 Experimental facility used for preparing spinal cord injury animal model

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
东乐自然基因生命科学公司: "全自动悬尾分析系统", 《易展仪表展览网》, 11 May 2011 (2011-05-11), pages 1 *
陈杰等: "一种模拟长期失重影响的大鼠尾部悬吊模型", 《空间科学学报》, vol. 13, no. 2, 30 April 1993 (1993-04-30), pages 159 - 162 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104138265A (en) * 2013-05-08 2014-11-12 上海交通大学医学院 Device for preventing climbing on tail in animal tail suspension test
CN111903607A (en) * 2020-08-11 2020-11-10 安徽正华生物仪器设备有限公司 Automatic analysis system and method based on deep learning rodent tail suspension experiment
CN111903607B (en) * 2020-08-11 2022-03-01 安徽正华生物仪器设备有限公司 Automatic analysis system and method based on deep learning rodent tail suspension experiment

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Application publication date: 20121219