CN102805821B - Traditional Chinese medicine compound used for preventing heatstroke - Google Patents
Traditional Chinese medicine compound used for preventing heatstroke Download PDFInfo
- Publication number
- CN102805821B CN102805821B CN201210299257.2A CN201210299257A CN102805821B CN 102805821 B CN102805821 B CN 102805821B CN 201210299257 A CN201210299257 A CN 201210299257A CN 102805821 B CN102805821 B CN 102805821B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- traditional chinese
- medicine compound
- heatstroke
- heat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
The invention provides a traditional Chinese medicine compound used for preventing heatstroke. A formula of the traditional Chinese medicine compound consists of five traditional Chinese medicines, namely radix rehmanniae, reed rhizome, raw gypsum, honeysuckle and folium mori, and is characterized in that the weight proportion of the traditional Chinese medicine raw materials of the radix rehmanniae to the reed rhizome to the raw gypsum to the honeysuckle to the folium mori is 1 to 1.5-2.5 to 0.2-1 to 0.5-1.2 to 0.3-1. The traditional Chinese medicine compound achieves the effects of endogenous fire elimination, summer-heat clearing, liquid engendering and thirst quenching, can well protect heat-exposed mice, and can be prepared into oral preparations stated by the pharmacy, which comprise decoction, dissolved medicines, powder, mixtures, solutions, bagged steeping drugs, granules, syrup, capsules and tablets, as well as drinks or special-purpose drinks.
Description
Technical field
The present invention relates to a kind of Chinese medicine compound for heatstroke, thermoplegia prevention, belong to technical field of Chinese medicines.
Background technology
Along with the rising of global temperature, heatstroke has become a kind of common disease that has a strong impact on life and health.How to accomplish to be equipped with, to effectively prevent the generation of heatstroke, reduce the negative effect that the personnel reduction that causes because of heatstroke or damage bring, become very important problem.
At present, common prevention heatstroke measure mainly contains: thermoacclimatization training, moisturizing mend salt, force ventilation, rationally arrange work rest program, alleviate clothing thermic load etc.Effectively prevent heatstroke, reduce the sickness rate of severe heat stroke, when carrying out the Physical temperature-lowering measure, from improving body thermostability and adaptability, supplementing water, electrolyte and nutrition effectively in time is important means and method.
Aspect medical treatment, treatment heatstroke Physical temperature-lowering commonly used be aided with medicine such as chlorpromazine, promethazine, tranquilizer such as stable, but effect is undesirable.Theory of Chinese medical science to being interpreted as of heatstroke " summer-heat for gas, in time, answer the summer.Being heat in the sky, be fiery on ground, at the artificial heart.The wound of summer-heat, earlier in the heart, the heresy of summer-heat seizes the opportunity to worm one's way into ".So will force " pathogen " out by every means, therefore normal the employing with mode expelling summer-heats such as acupuncture, scrape therapys.Aspect treatment and preventing and treating, then cloudy Chinese patent medicine is given birth in clearing away heat-fire, damp eliminating detoxifcation, foster Tianjin of adopting more, and fruitful.For example, treatment summer-heat light disease has electrodeless pellet, a rheocamphoradin.Treatment summer-heat serious symptom March Powder, summer-heat disease sheet, Yushu Dan arranged.The Chinese patent medicine of prevention heatstroke is more, and HUOXIANG ZHENGQI SHUI, rendan mini-pills, rheocamphoradin, menthocamphorate, essential balm, watermelon crystal, medicinal powder for preventing from seasonal febrile diseases etc. are arranged.Therefore, utilizing traditional Chinese medical science traditional theory and Chinese herbal medicine resource, carry out sunstroke prevention Chinese medicine or the research of Chinese herb prevention means, is the important channel that solves prevention and treatment heatstroke.
Summary of the invention
Technical problem to be solved by this invention is to utilize traditional Chinese medical science traditional theory and Chinese herbal medicine resource to solve the problem of prevention and treatment heatstroke.
In order to achieve the above object, the invention provides a kind of Chinese medicine compound for the prevention heatstroke, it is characterized in that it comprises following component in parts by weight: the Radix Rehmanniae 1 weight portion, Rhizoma Phragmitis 1.5-2.5 weight portion, Gypsum Fibrosum 0.2-1 weight portion, Flos Lonicerae 0.5-1.2 weight portion, Folium Mori 0.3-1 weight portion.
Adopt conventional processing method, making above-mentioned Chinese medicine compound is main oral formulations, and described oral formulations is decoction, electuary, powder, mixture, solution, bagged steeping drug, granule, syrup, capsule or tablet.
Above-mentioned for the application of the Chinese medicine compound of preventing heatstroke at preparation specific use beverage or functional drinks.
The mechanism of action of the present invention is: the Radix Rehmanniae is sweet in flavor and cold in property, and YIN nourishing and the production of body fluid promoting is arranged, and the effect of clearing away heat and cooling blood cures mainly summer high-temperature and takes off diseases such as liquid with heating back consumption of body fluid caused by febrile disease, and pharmacological testing confirms that the Radix Rehmanniae has the secretory action of bodies of gland such as strengthening saliva, gastric juice, intestinal juice; Rhizoma Phragmitis is sweet in flavor and cold in property, and the effect of promoting the production of body fluid to quench thirst, clearing away heat and nourishing YIN is arranged, and it is the health promoting beverage that summer among the people, clearing away summer-heat quenched one's thirst that Rhizoma Phragmitis boils soup; Gypsum Fibrosum has the effect of clearing away heat-fire, promoting the production of body fluid to quench thirst, has to reduce body temperature and the effect that promotes salivation, and taking for a long time still has the effect of replenishing the calcium; The Flos Lonicerae heat-clearing and toxic substances removing is the monarch drug of traditional prescription Lonicerae and Forsythiae Powder, and it is fallen flat for tea is the health promoting beverage that summer among the people, clearing away summer-heat quenched one's thirst; Folium Mori have the effect of clearing away heat to improve acuity of vision, are the monarch drug of traditional prescription SANGJU YIN, also are to make the quench one's thirst raw material commonly used of soup stock of sunstroke prevention summer among the people.The five kinds of Chinese medicine nature and flavor all are sweet cold in this prescription, be the spice commonly used of health promoting beverage among the people, take without any side effectsly for a long time, wherein the Radix Rehmanniae is monarch drug, and Rhizoma Phragmitis, Gypsum Fibrosum are ministerial drug, in heat clearing away with promote the production of body fluid and strengthened aspect two, Flos Lonicerae is assistant, and Folium Mori are removed endogenous fire for making, clearing away summer-heat is analgesic, promotes the production of body fluid to quench one's thirst.
The present invention utilizes traditional Chinese medical science traditional theory and Chinese herbal medicine resource to solve the problem of prevention and treatment heatstroke in conjunction with the good prospect of Chinese medicine application at present; The present invention has the removing endogenous fire, and clearing away summer-heat is analgesic, the effect of promoting the production of body fluid and quenching one's thirst, and component drug is less, obtains easily, and convenient and cheap, there is not significant side effects, have good market prospect.
The specific embodiment
For the present invention is become apparent, now with preferred embodiment, be described in detail below.
Embodiment 1
Prescription: Radix Rehmanniae 15g, Rhizoma Phragmitis 30g, Gypsum Fibrosum 10g, Flos Lonicerae 18g, Folium Mori 15g.
Method for making: the preparation of granule
Earlier each material component is pulverized, sieved, by prescription each raw material that takes by weighing accurate in scale.Gypsum Fibrosum is decocted first behind the 2h, and all the other raw materials except Gypsum Fibrosum decoct with water 3 times down, and each 2 hours, collecting decoction filtered, and concentrating under reduced pressure gets fluid extract, disperse afterwards to make extractum at 60 ℃ of following drying under reduced pressure 12h.Extractum is pulverized the back and is mixed, and granulates, and oven dry namely.
Embodiment 2
Prescription: Radix Rehmanniae 10g, Rhizoma Phragmitis 15g, Gypsum Fibrosum 5g, Flos Lonicerae 12g, Folium Mori 10g.
Method for making: the preparation of mixture
Earlier each material component is pulverized, sieved, by prescription each raw material that takes by weighing accurate in scale.Gypsum Fibrosum is added the water list fry in shallow oil 2h, the decocting liquid cooling is placed standby.All the other raw materials except Gypsum Fibrosum are decocted with water 3 times, each 2 hours, collecting decoction, filter, concentrating under reduced pressure gets fluid extract, adds ethanol, precipitate with ethanol 24h filters decompression recycling ethanol, add the Gypsum Fibrosum decocting liquid, cold preservation 24h filters, be settled to 500ml, after the packing, at 100 ℃ of 30min that sterilize down, namely.
The above-mentioned mixture that makes is diluted to finite concentration, can prepares a kind of specialty beverages for the prevention heatstroke.
Embodiment 3
Prescription: Radix Rehmanniae 10g, Rhizoma Phragmitis 25g, Gypsum Fibrosum 2g, Flos Lonicerae 5g, Folium Mori 3g.
Method for making: the preparation of capsule
Earlier each material component is pulverized, sieved, by prescription each raw material that takes by weighing accurate in scale.Gypsum Fibrosum is added the water list fry in shallow oil 2h, the decocting liquid cooling is placed standby.Other gets all the other raw materials except Gypsum Fibrosum, adds 75% alcohol reflux 3 times, and each 2 hours, merge extractive liquid,, filter, decompression recycling ethanol is not to there being the alcohol flavor, and surplus liquid and Gypsum Fibrosum decocting liquid merge, concentrating under reduced pressure gets fluid extract, disperses the back at 60 ℃ of following drying under reduced pressure 12h, makes extractum.Extractum is pulverized the back and is mixed, granulates, and oven dry, namely encapsulated.
Embodiment 4
Pharmacodynamic experiment
The extractum that makes by embodiment 1 described method is test sample, carries out the animal pharmacodynamic experiment, confirms that the Chinese medicine compound for the prevention heatstroke provided by the invention exposes mice to heat and has good protective action.
Get 50 of Kunming mouses, body weight 18-22g is divided into totally five groups of blank group, normal saline group, administration group on the five, administration group on the three, administration on same day groups, 10 every group at random.After the mice adaptability is fed a week, gastric infusion.Blank is organized not administration; The normal saline group was given and is irritated stomach 2ml normal saline in continuous five days; The administration group was irritated stomach 0.2ml (being equivalent to the crude drug amount to every mouse stomach 0.3g) test sample in continuous five days on 5th; The administration group exposed filling of continuous three days of first three day stomach 0.2ml test sample in heat on 3rd; Administration on same day group exposes in heat irritated stomach 0.2ml test sample the same day.After the administration, mice is put into the dedicated fixed box, is exposed to temperature and is in 41 ± 1 ℃ the constant incubator, the record time-to-live and dead before and after body weight change.The result is as follows:
Table 1
Compare with the blank group:
*P＜0.05,
*P＜0.01.
Wherein:
Geometrical mean; The s-standard deviation; The every treated animal number of elements of n-; Two groups of data t checks of P-probit;
*,
*The symbol of-sign difference degree.
By table 1 as seen, the Chinese medicine compound for the prevention heatstroke provided by the invention can effectively reduce heat and expose the mice loss of body fluids, prolongs the time-to-live of mice; Especially administration on same day group can significant prolongation heat exposes time-to-live of mice, shows that the present invention has the effect of prevention heatstroke preferably.
Claims (3)
1. a Chinese medicine compound that is used for the prevention heatstroke is characterized in that it comprises following component in parts by weight: the Radix Rehmanniae 1 weight portion, Rhizoma Phragmitis 1.5-2.5 weight portion, Gypsum Fibrosum 0.2-1 weight portion, Flos Lonicerae 0.5-1.2 weight portion, Folium Mori 0.3-1 weight portion.
2. the Chinese medicine compound for the prevention heatstroke according to claim 1 is characterized in that this Chinese medicine compound can be made into oral formulations, and described oral formulations is decoction, electuary, powder, mixture, solution, bagged steeping drug, syrup, capsule or tablet.
3. the described application that prevents the functional drinks of heatstroke for the Chinese medicine compound of prevention heatstroke in preparation of claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210299257.2A CN102805821B (en) | 2012-08-21 | 2012-08-21 | Traditional Chinese medicine compound used for preventing heatstroke |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210299257.2A CN102805821B (en) | 2012-08-21 | 2012-08-21 | Traditional Chinese medicine compound used for preventing heatstroke |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102805821A CN102805821A (en) | 2012-12-05 |
| CN102805821B true CN102805821B (en) | 2013-10-02 |
Family
ID=47229805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210299257.2A Expired - Fee Related CN102805821B (en) | 2012-08-21 | 2012-08-21 | Traditional Chinese medicine compound used for preventing heatstroke |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102805821B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105169119B (en) * | 2015-09-15 | 2018-11-13 | 临沂大学 | A kind of anti-rabbit heat stress oral solution and preparation method thereof |
| CN108887542A (en) * | 2018-05-25 | 2018-11-27 | 李红光 | A kind of nonalcoholic Summerheat-dispelling beverage |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1170594A (en) * | 1996-07-17 | 1998-01-21 | 滕明星 | Method for producing heatstroke preventing tea |
| CN1216220A (en) * | 1997-11-03 | 1999-05-12 | 济南铁路分局济南西铁路医院 | Heatstroke preventing tea |
| CN1640418A (en) * | 2004-01-07 | 2005-07-20 | 中国人民解放军军事医学科学院卫生学环境医学研究所 | Anti-heat stroke Chinese medicine |
-
2012
- 2012-08-21 CN CN201210299257.2A patent/CN102805821B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1170594A (en) * | 1996-07-17 | 1998-01-21 | 滕明星 | Method for producing heatstroke preventing tea |
| CN1216220A (en) * | 1997-11-03 | 1999-05-12 | 济南铁路分局济南西铁路医院 | Heatstroke preventing tea |
| CN1640418A (en) * | 2004-01-07 | 2005-07-20 | 中国人民解放军军事医学科学院卫生学环境医学研究所 | Anti-heat stroke Chinese medicine |
Non-Patent Citations (2)
| Title |
|---|
| 盛夏消暑茶;逢春;《东方药膳》;20071231(第7期);38 * |
| 逢春.盛夏消暑茶.《东方药膳》.2007,(第7期),38. |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102805821A (en) | 2012-12-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102225152B (en) | Preparation method of Maiwei rehmannia oral preparation | |
| CN101632769B (en) | Chinese medicinal composition for regulating blood sugar and preparation method thereof | |
| CN1985922B (en) | Medicine composition for treating common cold and its preparing method | |
| CN102551065A (en) | Blood sugar reducing food series | |
| CN102742700B (en) | Herbal tea | |
| CN102133271A (en) | Medicinal tea for curing gout | |
| CN103479691A (en) | Lipid-decreasing liver protection traditional Chinese medicine composition | |
| CN101129485A (en) | Pyrrosia lingua farw Tonglin beverage | |
| CN102805821B (en) | Traditional Chinese medicine compound used for preventing heatstroke | |
| CN103621992A (en) | Traditional Chinese medicinal healthcare food for promoting lactation, and preparation method thereof | |
| CN102210770A (en) | Medicament for treating dysentery, and preparation method thereof | |
| CN101703691A (en) | Chinese medicinal composition for treating gastrointestinal ulcer and hemorrhage, and preparation method thereof | |
| CN101293081B (en) | Medicament for treating hyperlipemia and preparation method thereof | |
| CN101780263A (en) | Traditional Chinese medicine composition for treating chronic gastritis and preparation method thereof | |
| CN108403818A (en) | A kind of composition of auxiliary hyperglycemic and application thereof | |
| CN104257846A (en) | Traditional Chinese medicine composition for preventing edema disease and preparation method thereof | |
| CN104126713A (en) | Siberian ginseng compound health-care cool tea and preparation method thereof | |
| CN100551424C (en) | A kind of Chinese medicine composition that is used for Dealcoholic sobering-up | |
| CN101073657B (en) | 'Traditional Chinese-medicinal preparation for treating oral ulcers | |
| CN104587175B (en) | A kind of Chinese medicine preparation for treating diabetes | |
| CN103566349B (en) | A kind of pharmaceutical composition for the treatment of hyperglycemia hyperlipidemia | |
| CN104083741A (en) | Traditional Chinese medicinal composition for treating chronic gastritis and preparation method thereof | |
| CN1191086C (en) | Medicine for treating cold in summer and autumn | |
| CN101129853A (en) | Beverage for clearing lung-heat and relieving cough | |
| CN112494626B (en) | Tablet with protective effect on chemical liver injury and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20131002 Termination date: 20170821 |