CN102783952B - Treatment method and solution of human body vein blood specimen collection container for preventing blood from being remained on wall - Google Patents
Treatment method and solution of human body vein blood specimen collection container for preventing blood from being remained on wall Download PDFInfo
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- CN102783952B CN102783952B CN201210276454.2A CN201210276454A CN102783952B CN 102783952 B CN102783952 B CN 102783952B CN 201210276454 A CN201210276454 A CN 201210276454A CN 102783952 B CN102783952 B CN 102783952B
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- test tube
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- collection container
- specimen collection
- agent layer
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- 210000004369 blood Anatomy 0.000 title claims abstract description 35
- 239000008280 blood Substances 0.000 title claims abstract description 35
- 210000003462 vein Anatomy 0.000 title claims abstract description 14
- 238000000034 method Methods 0.000 title abstract description 5
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 37
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 18
- 238000004140 cleaning Methods 0.000 claims abstract description 16
- 238000002360 preparation method Methods 0.000 claims abstract description 15
- 238000001035 drying Methods 0.000 claims abstract description 14
- 238000004806 packaging method and process Methods 0.000 claims abstract description 7
- 238000002372 labelling Methods 0.000 claims abstract description 5
- 238000007789 sealing Methods 0.000 claims abstract description 5
- 229960000935 dehydrated alcohol Drugs 0.000 claims description 15
- 239000007788 liquid Substances 0.000 claims description 13
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 12
- 230000001194 anti-hemostatic effect Effects 0.000 claims description 12
- 229910052710 silicon Inorganic materials 0.000 claims description 12
- 239000010703 silicon Substances 0.000 claims description 12
- 238000003672 processing method Methods 0.000 claims description 6
- 210000000988 bone and bone Anatomy 0.000 claims description 5
- 239000011248 coating agent Substances 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- 239000006260 foam Substances 0.000 abstract description 6
- 230000035699 permeability Effects 0.000 abstract description 4
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 238000002791 soaking Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 description 9
- 238000010276 construction Methods 0.000 description 6
- 239000008213 purified water Substances 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 239000002904 solvent Substances 0.000 description 4
- 241000973497 Siphonognathus argyrophanes Species 0.000 description 3
- 238000005119 centrifugation Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000000701 coagulant Substances 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 239000002985 plastic film Substances 0.000 description 2
- 229920006255 plastic film Polymers 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 1
- 210000003677 hemocyte Anatomy 0.000 description 1
- 229940000351 hemocyte Drugs 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
Abstract
The invention provides a treatment method and a solution of a human body vein blood specimen collection container for preventing blood from being remained on a wall. The method comprises the following steps of: a cleaning step, a silicification agent layer preparation step, a drying step, an additive adding step, a vacuumizing step, a sealing step, a labeling step and a packaging step which are sequentially carried out, wherein the silicification agent layer preparation step is characterized by preparing the solution according to the proportion of water-soluble silicification agent to absolute ethyl alcohol being 1:(100-1000), then completely soaking a cleaned test tube into the solution for 1-3min, taking the test tube out, and draining. According to the method, the absolute ethyl alcohol is used as a dissolvent to prepare a silicification agent layer, has better volatility, is easy to dry, cannot enable the silicification agent layer to form a firm structure on the surface of the test tube, and has better permeability; and foam cannot be generated after the water-soluble silicification agent is dissolved in the absolute ethyl alcohol, so that the silicification uniformity is better, and the phenomenon that blood is remained on the wall after blood drawing through the test tube can be well eliminated.
Description
[technical field]
The present invention relates to a kind of processing method and Treatment Solution of anti-Hemostatic Oral Liquid wall built-up of human vein blood specimen collection container.
[background technology]
In the preparation process of disposable human vein blood specimen collection container, comprise the following steps:
1, clean: by test tube cleaning;
2, preparation silication agent layer: the test tube of cleaning is soaked in to 1-3min in the solution that water-soluble silicon agent and purified water prepare, prepares a coating with wall in vitro, in case Hemostatic Oral Liquid wall cling phenomenon;
3, dry: under the condition of 180 DEG C, dry 2 hours;
4, doping: add coagulant;
5, evacuation: then by test tube extracting vacuum;
6, sealing: cover safety head and seal;
7, labeling: on test tube outer wall, stick paper labels,
8, packaging: test tube is arranged in foam pallet fixing, finally complete with plastic film packaging.
But the solution that above-mentioned preparation method is prepared in silication agent layer with regard to using water-soluble silicon agent and purified water preparation is prepared, and can have the following defect that cannot overcome at present: be difficult for dry; Silication agent layer after dry solidification can form strong construction in test tube surface, and when use, hemocyte adheres to rear difficult drop-off, namely causes blood wall cling phenomenon; The silication uniformity is poor;
Find after deliberation, above-mentioned defect is because silication agent layer is to use purified water to be prepared and to cause as solvent: purified water volatility is poor, cause baking temperature to need higher, therefore the silication agent layer after high temperature drying is solidified can form strong construction in test tube surface; In addition, purified water is poor as its permeability of solvent, affects the silication uniformity; And water-soluble silicon agent can produce foam after being dissolved in purified water, and lather collapse place can produce silication non-uniform phenomenon.
[summary of the invention]
One of the technical problem to be solved in the present invention, be the processing method of the anti-Hemostatic Oral Liquid wall built-up that a kind of human vein blood specimen collection container is provided, easily dry, can not make silication agent layer form strong construction in test tube surface, and the silication uniformity is better, eliminate preferably the blood wall cling phenomenon of test tube.
One of the technical problem to be solved in the present invention is achieved in that a kind of processing method of anti-Hemostatic Oral Liquid wall built-up of human vein blood specimen collection container, comprise the cleaning step, preparation silication agent layer step, drying steps, doping step, evacuation step, sealing step, labeling step and the packaging step that carry out successively, the ratio obtain solution that described preparation silication agent layer step is is first 1:100 ~ 1000 in water-soluble silicon agent and dehydrated alcohol ratio, then the test tube of cleaning is soaked in completely to this solution 1 ~ 3min, take out test tube, and drain.
Further, described drying steps is that the test tube after draining is placed in drying baker, uses and is not dried higher than the temperature of 100 DEG C, until bone dry.
Two of the technical problem to be solved in the present invention, be the Treatment Solution of the anti-Hemostatic Oral Liquid wall built-up that a kind of human vein blood specimen collection container is provided, be used for making inboard wall of test tube to prepare after silication agent layer, easily dry, can not make silication agent layer form strong construction in test tube surface, and the silication uniformity is better, eliminate preferably the blood wall cling phenomenon of test tube.
The ratio that described Treatment Solution is is 1:100 ~ 1000 in water-soluble silicon agent and dehydrated alcohol ratio is prepared the solution obtaining, and described Treatment Solution is for the preparation of the coating of human vein blood specimen collection container.
Tool of the present invention has the following advantages: the present invention uses dehydrated alcohol to be prepared silication agent layer as solvent, the dehydrated alcohol property sent out is better, easily dry, use lower than the temperature of 100 DEG C and be dried, can not make silication agent layer form strong construction in test tube surface, and dehydrated alcohol permeability is better, and water-soluble silicon agent can not produce foam after being dissolved in dehydrated alcohol, make the silication uniformity better, eliminate preferably the blood wall cling phenomenon of test tube.
[detailed description of the invention]
Introduce in detail several embodiment below so that the present invention is further illustrated.Each embodiment all comprises Treatment Solution and method two parts of the anti-Hemostatic Oral Liquid wall built-up of human vein blood specimen collection container of the present invention:
Embodiment mono-
1, cleaning step: by test tube cleaning;
2, preparation silication agent layer step: the ratio obtain solution that is first 1:1000 in water-soluble silicon agent and dehydrated alcohol ratio, as the Treatment Solution of anti-Hemostatic Oral Liquid wall built-up, is then soaked in the test tube of cleaning this solution 3min completely, takes out test tube, and drains;
3, drying steps: the test tube after draining is placed in drying baker, uses the temperature of 100 DEG C to be dried, until bone dry;
4, doping step: add coagulant;
5, evacuation step: then by test tube extracting vacuum;
6, sealing step: cover safety head and seal;
7, labeling step: on test tube outer wall, stick paper labels,
8, packaging step: test tube is arranged in foam pallet fixing, finally complete with plastic film packaging.
Effect proves:
1, get 5, disposable end user's vena systemica blood specimen collection container of preparing by above-mentioned steps, extract blood donor's blood the most pure virginity spatial capacity;
2, by the test tube mouth of pipe upward, while waiting blood upper strata to have more amount serum to separate out, (general 15-20 minute), carries out centrifugally operated (the centrifugal relative centrifugal force(RCF) that requires arranges 3000 grams, and centrifugation time arranges 5-15 minute).
3, centrifugal rear observation serum state, can find that serum is bright, does not have any wall cling phenomenon.
Embodiment bis-
1, cleaning step: by test tube cleaning;
2, preparation silication agent layer step: the ratio obtain solution that is first 1:500 in water-soluble silicon agent and dehydrated alcohol ratio, as the Treatment Solution of anti-Hemostatic Oral Liquid wall built-up, is then soaked in the test tube of cleaning this solution 2min completely, takes out test tube, and drains;
3, drying steps: the test tube after draining is placed in drying baker, uses and be not dried higher than the temperature of 80 DEG C, until bone dry;
Other step is with embodiment mono-.
Effect proves:
1, get 5, disposable end user's vena systemica blood specimen collection container of preparing by above-mentioned steps, extract blood donor's blood the most pure virginity spatial capacity;
2, by the test tube mouth of pipe upward, while waiting blood upper strata to have more amount serum to separate out, (general 15-20 minute), carries out centrifugally operated (the centrifugal relative centrifugal force(RCF) that requires arranges 3000 grams, and centrifugation time arranges 5-15 minute).
3, centrifugal rear observation serum state, can find that serum is bright, does not have any wall cling phenomenon.
Embodiment tri-
1, cleaning step: by test tube cleaning;
2, preparation silication agent layer step: the ratio obtain solution that is first 1:100 in water-soluble silicon agent and dehydrated alcohol ratio, as the Treatment Solution of anti-Hemostatic Oral Liquid wall built-up, is then soaked in the test tube of cleaning this solution 1min completely, takes out test tube, and drains;
3, drying steps: the test tube after draining is placed in drying baker, uses and be not dried higher than the temperature of 50 DEG C, until bone dry;
Other step is with embodiment mono-.
Effect proves:
1, get 5, disposable end user's vena systemica blood specimen collection container of preparing by above-mentioned steps, extract blood donor's blood the most pure virginity spatial capacity;
2, by the test tube mouth of pipe upward, while waiting blood upper strata to have more amount serum to separate out, (general 15-20 minute), carries out centrifugally operated (the centrifugal relative centrifugal force(RCF) that requires arranges 3000 grams, and centrifugation time arranges 5-15 minute).
3, centrifugal rear observation serum state, can find that serum is bright, does not have any wall cling phenomenon.
As previously mentioned, the present invention uses dehydrated alcohol to be prepared silication agent layer as solvent, the dehydrated alcohol property sent out is better, easily dry, use lower than the temperature of 100 DEG C and be dried, can not make silication agent layer form strong construction in test tube surface, and dehydrated alcohol permeability is better, and water-soluble silicon agent can not produce foam after being dissolved in dehydrated alcohol, makes the silication uniformity better, eliminates preferably the blood wall cling phenomenon of test tube.
Although more than described the specific embodiment of the present invention; but being familiar with those skilled in the art is to be understood that; our described specific embodiment is illustrative; instead of for the restriction to scope of the present invention; those of ordinary skill in the art are in equivalent modification and the variation done according to spirit of the present invention, all should be encompassed in the scope that claim of the present invention protects.
Claims (3)
1. the processing method of the anti-Hemostatic Oral Liquid wall built-up of human vein blood specimen collection container, comprise the cleaning step, preparation silication agent layer step, drying steps, doping step, evacuation step, sealing step, labeling step and the packaging step that carry out successively, it is characterized in that:
The ratio obtain solution that described preparation silication agent layer step is is first 1:100 ~ 1000 in water-soluble silicon agent and dehydrated alcohol ratio, is then soaked in the test tube of cleaning this solution 1 ~ 3min completely, takes out test tube, and drains.
2. the processing method of the anti-Hemostatic Oral Liquid wall built-up of a kind of human vein blood specimen collection container according to claim 1, it is characterized in that: described drying steps is that the test tube after draining is placed in drying baker, use and be not dried higher than the temperature of 100 DEG C, until bone dry.
3. the Treatment Solution of the anti-Hemostatic Oral Liquid wall built-up of human vein blood specimen collection container, it is characterized in that: the ratio that described Treatment Solution is is 1:100 ~ 1000 in water-soluble silicon agent and dehydrated alcohol ratio is prepared the solution obtaining, and described Treatment Solution is for the preparation of the coating of human vein blood specimen collection container.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210276454.2A CN102783952B (en) | 2012-08-03 | 2012-08-03 | Treatment method and solution of human body vein blood specimen collection container for preventing blood from being remained on wall |
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| CN201210276454.2A CN102783952B (en) | 2012-08-03 | 2012-08-03 | Treatment method and solution of human body vein blood specimen collection container for preventing blood from being remained on wall |
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| CN102783952B true CN102783952B (en) | 2014-10-22 |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102785799B (en) * | 2012-09-04 | 2014-04-23 | 吴忠市嘉信塑料制品制造有限公司 | Detecting/counting equipment for bendable drinking straw |
| CN103690177B (en) * | 2013-12-27 | 2015-06-10 | 迈得医疗工业设备股份有限公司 | Automatic assembling process for medical vacuum blood collection tubes |
| CN106005605A (en) * | 2016-05-13 | 2016-10-12 | 江西广炅中药饮片有限公司 | Treatment method for traditional Chinese medicine accommodation bottles |
| CN107670145B (en) | 2016-08-01 | 2021-09-14 | 北京唐颐惠康生物医学技术有限公司 | Infusion pump and infusion method special for stem cells |
| CN116426189A (en) * | 2023-04-04 | 2023-07-14 | 安徽信灵检验医学科技股份有限公司 | Wall-hanging prevention treatment fluid and preparation method and application thereof |
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| US3941876A (en) * | 1973-04-25 | 1976-03-02 | Gte New Ventures Corporation | In vitro method for determining allergic hypersensitivity |
| CN101099969A (en) * | 2006-07-04 | 2008-01-09 | 深圳迈瑞生物医疗电子股份有限公司 | Wiper for cleaning sampling needle |
| CN101543640A (en) * | 2008-03-27 | 2009-09-30 | 张博 | Absorbable, conglutination preventing and styptic power product and preparation method thereof |
| CN201997431U (en) * | 2010-12-22 | 2011-10-05 | 衡阳鑫山机械设备制造有限公司 | Test tube flushing and liquid masking machine |
| CN202185434U (en) * | 2011-07-28 | 2012-04-11 | 湖南邦华医疗用品有限公司 | Ultrasonic cleaning siliconization machine for blood collection tube |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007063180A (en) * | 2005-08-31 | 2007-03-15 | Frontier Kenkyusho:Kk | Method of detecting new quinolone antibacterial agent |
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2012
- 2012-08-03 CN CN201210276454.2A patent/CN102783952B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3941876A (en) * | 1973-04-25 | 1976-03-02 | Gte New Ventures Corporation | In vitro method for determining allergic hypersensitivity |
| CN101099969A (en) * | 2006-07-04 | 2008-01-09 | 深圳迈瑞生物医疗电子股份有限公司 | Wiper for cleaning sampling needle |
| CN101543640A (en) * | 2008-03-27 | 2009-09-30 | 张博 | Absorbable, conglutination preventing and styptic power product and preparation method thereof |
| CN201997431U (en) * | 2010-12-22 | 2011-10-05 | 衡阳鑫山机械设备制造有限公司 | Test tube flushing and liquid masking machine |
| CN202185434U (en) * | 2011-07-28 | 2012-04-11 | 湖南邦华医疗用品有限公司 | Ultrasonic cleaning siliconization machine for blood collection tube |
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| CN102783952A (en) | 2012-11-21 |
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Denomination of invention: Treatment method and solution of human body vein blood specimen collection container for preventing blood from being remained on wall Effective date of registration: 20190923 Granted publication date: 20141022 Pledgee: China Exim Bank Fujian branch Pledgor: FUZHOU CHANGGENG MEDICAL DEVICES CO.,LTD. Registration number: Y2019350000027 |
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Denomination of invention: Treatment method and solution of preventing blood from hanging on the wall of human venous blood collection container Effective date of registration: 20200910 Granted publication date: 20141022 Pledgee: China Exim Bank Fujian branch Pledgor: FUZHOU CHANGGENG MEDICAL DEVICES Co.,Ltd. Registration number: Y2020350000107 |
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Denomination of invention: Treatment method and solution for preventing blood from hanging on the wall of human venous blood sample collection container Effective date of registration: 20211019 Granted publication date: 20141022 Pledgee: China Exim Bank Fujian branch Pledgor: FUZHOU CHANGGENG MEDICAL DEVICES Co.,Ltd. Registration number: Y2021350000140 |
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Denomination of invention: Treatment methods and solutions for preventing blood from hanging on the wall of human venous blood sample collection containers Effective date of registration: 20231011 Granted publication date: 20141022 Pledgee: China Exim Bank Fujian branch Pledgor: FUZHOU CHANGGENG MEDICAL DEVICES CO.,LTD. Registration number: Y2023980060461 |
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