CN102772380B - 固体药物剂型 - Google Patents
固体药物剂型 Download PDFInfo
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- CN102772380B CN102772380B CN201210259721.5A CN201210259721A CN102772380B CN 102772380 B CN102772380 B CN 102772380B CN 201210259721 A CN201210259721 A CN 201210259721A CN 102772380 B CN102772380 B CN 102772380B
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- amino
- methyl
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- carbonyl
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61K9/20—Pills, tablets, discs, rods
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- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/650178 | 2003-08-28 | ||
| US10/650,178 US20050048112A1 (en) | 2003-08-28 | 2003-08-28 | Solid pharmaceutical dosage form |
| CN200480024748XA CN1901884B (zh) | 2003-08-28 | 2004-08-23 | 固体药物剂型 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200480024748XA Division CN1901884B (zh) | 2003-08-28 | 2004-08-23 | 固体药物剂型 |
Publications (2)
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|---|---|
| CN102772380A CN102772380A (zh) | 2012-11-14 |
| CN102772380B true CN102772380B (zh) | 2015-08-19 |
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| CN2012102597395A Pending CN102764244A (zh) | 2003-08-28 | 2004-08-23 | 固体药物剂型 |
| CN2010102227346A Ceased CN101919858B (zh) | 2003-08-28 | 2004-08-23 | 固体药物剂型 |
| CN201210259721.5A Ceased CN102772380B (zh) | 2003-08-28 | 2004-08-23 | 固体药物剂型 |
| CN200480024748XA Ceased CN1901884B (zh) | 2003-08-28 | 2004-08-23 | 固体药物剂型 |
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| CN201510531654.1A Pending CN105106104A (zh) | 2003-08-28 | 2004-08-23 | 固体药物剂型 |
| CN2012102597395A Pending CN102764244A (zh) | 2003-08-28 | 2004-08-23 | 固体药物剂型 |
| CN2010102227346A Ceased CN101919858B (zh) | 2003-08-28 | 2004-08-23 | 固体药物剂型 |
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Country Status (31)
| Country | Link |
|---|---|
| US (1) | US20050048112A1 (ja) |
| EP (6) | EP2258345B1 (ja) |
| JP (6) | JP4815348B2 (ja) |
| KR (5) | KR20150044031A (ja) |
| CN (5) | CN105106104A (ja) |
| AT (1) | ATE516017T1 (ja) |
| AU (3) | AU2004283087C1 (ja) |
| CA (2) | CA2689639C (ja) |
| CR (3) | CR8256A (ja) |
| CY (5) | CY1111981T1 (ja) |
| DK (5) | DK2258345T3 (ja) |
| EA (4) | EA033224B1 (ja) |
| EC (1) | ECSP066397A (ja) |
| ES (5) | ES2608720T3 (ja) |
| HK (4) | HK1094766A1 (ja) |
| HR (1) | HRP20110555T1 (ja) |
| HU (3) | HUE031153T2 (ja) |
| IL (3) | IL173939A (ja) |
| ME (2) | MEP17608A (ja) |
| MX (2) | MXPA06002346A (ja) |
| NO (3) | NO330282B1 (ja) |
| NZ (2) | NZ545499A (ja) |
| PL (5) | PL2258344T3 (ja) |
| PT (5) | PT2258346T (ja) |
| RS (2) | RS57663B1 (ja) |
| SG (3) | SG179401A1 (ja) |
| SI (5) | SI1663183T1 (ja) |
| TW (1) | TWI342221B (ja) |
| UA (1) | UA85564C2 (ja) |
| WO (1) | WO2005039551A2 (ja) |
| ZA (3) | ZA200801362B (ja) |
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| CN114146061B (zh) * | 2020-09-07 | 2023-06-30 | 歌礼生物科技（杭州）有限公司 | 包含固体分散体的蛋白酶抑制剂增效组合物及其制备方法 |
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-
2003
- 2003-08-28 US US10/650,178 patent/US20050048112A1/en not_active Abandoned
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2004
- 2004-08-23 EP EP10181264.2A patent/EP2258345B1/en not_active Revoked
- 2004-08-23 KR KR20157009392A patent/KR20150044031A/ko not_active Application Discontinuation
- 2004-08-23 NZ NZ545499A patent/NZ545499A/en not_active IP Right Cessation
- 2004-08-23 WO PCT/US2004/027401 patent/WO2005039551A2/en active Application Filing
- 2004-08-23 AU AU2004283087A patent/AU2004283087C1/en not_active Revoked
- 2004-08-23 PL PL10181250T patent/PL2258344T3/pl unknown
- 2004-08-23 CA CA2689639A patent/CA2689639C/en not_active Expired - Fee Related
- 2004-08-23 DK DK10181264.2T patent/DK2258345T3/en active
- 2004-08-23 EP EP15169378.5A patent/EP2942051B1/en not_active Revoked
- 2004-08-23 PL PL15169378T patent/PL2942051T3/pl unknown
- 2004-08-23 CN CN201510531654.1A patent/CN105106104A/zh active Pending
- 2004-08-23 PT PT101812683T patent/PT2258346T/pt unknown
- 2004-08-23 KR KR1020067004057A patent/KR101132602B1/ko active IP Right Grant
- 2004-08-23 EA EA201301045A patent/EA033224B1/ru not_active IP Right Cessation
- 2004-08-23 SI SI200431719T patent/SI1663183T1/sl unknown
- 2004-08-23 CA CA2536638A patent/CA2536638C/en not_active Expired - Fee Related
- 2004-08-23 ZA ZA200801362A patent/ZA200801362B/en unknown
- 2004-08-23 DK DK10181250.1T patent/DK2258344T3/da active
- 2004-08-23 EP EP10181268.3A patent/EP2258346B1/en not_active Revoked
- 2004-08-23 JP JP2006524782A patent/JP4815348B2/ja not_active Expired - Lifetime
- 2004-08-23 PL PL10181268T patent/PL2258346T3/pl unknown
- 2004-08-23 SI SI200432367A patent/SI2258345T1/sl unknown
- 2004-08-23 NZ NZ579622A patent/NZ579622A/en not_active IP Right Cessation
- 2004-08-23 EA EA201890737A patent/EA201890737A3/ru unknown
- 2004-08-23 CN CN2012102597395A patent/CN102764244A/zh active Pending
- 2004-08-23 EA EA200900292A patent/EA020992B1/ru not_active IP Right Cessation
- 2004-08-23 RS YU20060140A patent/RS57663B1/sr unknown
- 2004-08-23 PT PT101812642T patent/PT2258345T/pt unknown
- 2004-08-23 RS RS20181262A patent/RS59969B1/sr unknown
- 2004-08-23 CN CN2010102227346A patent/CN101919858B/zh not_active Ceased
- 2004-08-23 HU HUE10181264A patent/HUE031153T2/en unknown
- 2004-08-23 CN CN201210259721.5A patent/CN102772380B/zh not_active Ceased
- 2004-08-23 SI SI200432438T patent/SI2942051T1/en unknown
- 2004-08-23 PL PL04816820T patent/PL1663183T3/pl unknown
- 2004-08-23 KR KR1020127011945A patent/KR101457967B1/ko active IP Right Grant
- 2004-08-23 SG SG2012008959A patent/SG179401A1/en unknown
- 2004-08-23 HU HUE10181268A patent/HUE035985T2/hu unknown
- 2004-08-23 AT AT04816820T patent/ATE516017T1/de active
- 2004-08-23 ES ES10181264.2T patent/ES2608720T3/es not_active Expired - Lifetime
- 2004-08-23 MX MXPA06002346A patent/MXPA06002346A/es active IP Right Grant
- 2004-08-23 EP EP10181250A patent/EP2258344B1/en not_active Revoked
- 2004-08-23 KR KR1020117025014A patent/KR101281994B1/ko active IP Right Grant
- 2004-08-23 ES ES15169378.5T patent/ES2666390T3/es not_active Expired - Lifetime
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- 2004-08-23 ME MEP-176/08A patent/MEP17608A/xx unknown
- 2004-08-23 ES ES10181250T patent/ES2399810T3/es not_active Expired - Lifetime
- 2004-08-23 ES ES04816820T patent/ES2367173T3/es not_active Expired - Lifetime
- 2004-08-23 SG SG200805563-4A patent/SG145690A1/en unknown
- 2004-08-23 PT PT151693785T patent/PT2942051T/pt unknown
- 2004-08-23 DK DK04816820.7T patent/DK1663183T3/da active
- 2004-08-23 DK DK10181268.3T patent/DK2258346T3/da active
- 2004-08-23 PT PT04816820T patent/PT1663183E/pt unknown
- 2004-08-23 EA EA200600473A patent/EA011924B1/ru not_active IP Right Cessation
- 2004-08-23 ES ES10181268.3T patent/ES2653762T3/es not_active Expired - Lifetime
- 2004-08-23 KR KR1020147007592A patent/KR101563222B1/ko active IP Right Grant
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- 2004-08-23 DK DK15169378.5T patent/DK2942051T3/en active
- 2004-08-23 PT PT101812501T patent/PT2258344E/pt unknown
- 2004-08-23 UA UAA200603276A patent/UA85564C2/ru unknown
- 2004-08-23 EP EP04816820A patent/EP1663183B9/en not_active Revoked
- 2004-08-23 CN CN200480024748XA patent/CN1901884B/zh not_active Ceased
- 2004-08-23 ME MEP-2008-176A patent/ME00130B/me unknown
- 2004-08-23 PL PL10181264T patent/PL2258345T3/pl unknown
- 2004-08-23 SI SI200432412T patent/SI2258346T1/sl unknown
- 2004-08-23 MX MX2010013145A patent/MX358033B/es unknown
- 2004-08-23 EP EP17210362.4A patent/EP3354261A1/en not_active Withdrawn
- 2004-08-23 HU HUE15169378A patent/HUE038792T2/hu unknown
- 2004-08-27 TW TW093125927A patent/TWI342221B/zh active
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2006
- 2006-02-23 CR CR8256A patent/CR8256A/es unknown
- 2006-02-24 EC EC2006006397A patent/ECSP066397A/es unknown
- 2006-02-26 IL IL173939A patent/IL173939A/en active IP Right Grant
- 2006-02-27 ZA ZA200601718A patent/ZA200601718B/xx unknown
- 2006-03-24 NO NO20061342A patent/NO330282B1/no not_active Application Discontinuation
- 2006-12-06 HK HK06113444.9A patent/HK1094766A1/xx not_active IP Right Cessation
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2007
- 2007-12-19 AU AU2007249115A patent/AU2007249115B2/en not_active Revoked
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2008
- 2008-02-08 ZA ZA2008/01361A patent/ZA200801361B/en unknown
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2010
- 2010-03-15 NO NO20100367A patent/NO334418B1/no not_active Application Discontinuation
- 2010-07-27 IL IL207260A patent/IL207260A/en active IP Right Grant
- 2010-11-01 AU AU2010238573A patent/AU2010238573B2/en not_active Revoked
- 2010-12-30 HK HK10112283.9A patent/HK1145969A1/xx not_active IP Right Cessation
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2011
- 2011-02-18 JP JP2011032972A patent/JP5498411B2/ja not_active Expired - Lifetime
- 2011-07-06 JP JP2011149721A patent/JP5395125B2/ja not_active Expired - Lifetime
- 2011-07-25 HR HR20110555T patent/HRP20110555T1/hr unknown
- 2011-09-22 CY CY20111100923T patent/CY1111981T1/el unknown
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2012
- 2012-12-21 CR CR20120662A patent/CR20120662A/es unknown
- 2012-12-21 CR CR20120661A patent/CR20120661A/es unknown
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2013
- 2013-02-01 CY CY20131100093T patent/CY1113596T1/el unknown
- 2013-08-13 JP JP2013168001A patent/JP5903413B2/ja not_active Expired - Lifetime
- 2013-12-27 NO NO20131743A patent/NO335326B1/no not_active Application Discontinuation
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2015
- 2015-12-04 JP JP2015237449A patent/JP2016094433A/ja not_active Withdrawn
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2016
- 2016-05-10 HK HK16105307.9A patent/HK1217298A1/zh not_active IP Right Cessation
- 2016-12-19 CY CY20161101315T patent/CY1118505T1/el unknown
-
2017
- 2017-09-11 JP JP2017173733A patent/JP2018035163A/ja active Pending
- 2017-09-18 IL IL254581A patent/IL254581A0/en unknown
- 2017-11-03 CY CY20171101155T patent/CY1119651T1/el unknown
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2018
- 2018-04-17 CY CY20181100407T patent/CY1120138T1/el unknown
- 2018-12-19 HK HK18116294.9A patent/HK1257502A1/zh unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001034119A2 (en) * | 1999-11-12 | 2001-05-17 | Abbott Laboratories | Inhibitors of crystallization in a solid dispersion |
| WO2004032903A2 (de) * | 2002-10-09 | 2004-04-22 | Abbott Gmbh & Co. Kg | Herstellung von festen dosierungsformen unter verwendung eines vernetzten nicht-thermoplastischen trägers |
Also Published As
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| Publication | Publication Date | Title |
|---|---|---|
| CN102772380B (zh) | 固体药物剂型 | |
| US8268349B2 (en) | Solid pharmaceutical dosage form |
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