CN102771786A - Propolis and lucid ganoderma soft capsule with health care function and preparation method of propolis and lucid ganoderma soft capsule - Google Patents
Propolis and lucid ganoderma soft capsule with health care function and preparation method of propolis and lucid ganoderma soft capsule Download PDFInfo
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Abstract
The invention discloses a propolis and lucid ganoderma soft capsule with a health care function and a preparation method of the propolis and lucid ganoderma soft capsule. Filling materials of the propolis and lucid ganoderma soft capsule comprise the following ingredients in percent by weight: 15 to 17 percent of lucid ganoderma extracts, 13 to 15 percent of propolis extracts, 64 to 67 percent of soybean oil and 4 to 5 percent of beewax. A capsule case of the capsule comprises the following ingredients in percentage by weight: 41 to 42 percent of gelatin, 37 to 38 percent of purified water, 20.5 to 21.0 percent of glycerol and 0.5 to 0.7 percent of brown ferric oxide. The propolis and lucid ganoderma soft capsule reserves the prevention and treatment effects and health care functions of the propolis and the lucid ganoderma, including broad-spectrum antibiotic effect, anti-inflammatory and analgesic effect, tissue cell regeneration promotion, anti-tumor effect, hepatopathy prevention, gastric ulcer treatment, oral cavity diseases, triglyceride reduction, cholesterol, blood sugar regulation, insomnia and anti-aging effect, and in addition, the functions of improving the immune capability and reducing the blood sugar are also added.
Description
Technical field
The present invention relates to field of health care food, be specifically related to a kind of propolis ganoderma lucidum soft capsule that health care is arranged and preparation method thereof.
Background technology
The propolis resin (natural gum) that to be honeybee gather from plant gemma or trunk is sneaked into a kind of colloidal solid thing with aromatic odor that the secretion of palatine gland on it, wax gland processes.Contain the flavone compound more than 70 kinds, multiple alkene, terpenoid, amino acid, vitamin B complex, mineral matter and the trace element of trace, multiple organic acid etc. in the propolis, propolis has broad-spectrum antiseptic, anti-inflammatory and antalgic, the regeneration of promotion histocyte, antitumor, treatment gastric ulcer, the function of mouth disease, propolis to reduce the function of triglyceride, cholesterol and adjusting blood sugar in addition.Glossy ganoderma is a kind of large-scale medicinal fungi; Scientific research shows; The pharmaceutical component of glossy ganoderma is very abundant; Wherein active ingredient can be divided into ten big types, comprises GL-B, glossy ganoderma polypeptide, triterpenes, 16 seed amino acids (wherein containing seven kinds of essential amino acids), protein, steroid class, sweet mellow wine, coumarin glycosides, alkaloid, organic acid (the main fumaric acid that contains), and various trace elements etc.Glossy ganoderma has dual regulation to human body; To each systems such as cardiovascular and cerebrovascular, digestion, nerve, endocrine, breathing, motions; Especially to tumour, hepatic disease, insomnia and antidotal preventive and therapeutic effect very significantly, be human health care, the treasure of supplemental treatment.
The propolis ganoderma lucidum soft capsule is that the extract with propolis and glossy ganoderma processes according to scientific formula, though natural propolis and glossy ganoderma have stronger health protection and therapeutic action; The consumer can't directly eat; The propolis ganoderma lucidum soft capsule of the explained hereafter through advanced, science had both kept all active ingredient of propolis and glossy ganoderma, had solved the difficult problem that natural propolis and glossy ganoderma eat inconvenience again; Simultaneously; Through inventing prescription, increase this product and improved body immunity and the function that reduces blood sugar, give human health-care good product for enjoyment the Nature fast way is provided.
Summary of the invention
The invention provides a kind of propolis ganoderma lucidum soft capsule that health care is arranged and preparation method thereof.
Propolis ganoderma lucidum soft capsule of the present invention has also increased and has improved body immunity and the function that reduces blood sugar except that the health care of the broad-spectrum antiseptic that has kept propolis, glossy ganoderma, anti-inflammatory and antalgic, the regeneration of promotion histocyte, antitumor, hepatic disease, treatment gastric ulcer, mouth disease, reduction triglyceride, cholesterol and adjusting blood sugar, insomnia and antidotal preventive and therapeutic effect.
For realizing above-mentioned purpose, the present invention has adopted following technological preparation scheme:
The propolis ganoderma lucidum soft capsule of health care is arranged, and the weight proportion of its filler component is: Ganodenna Lucidum P.E 15-17%, propolis extract 13-15%, soybean oil 64-67%, beeswax 4-5%; The weight proportion of its softgel shell component is: gelatin 41-42%, purified water 37-38%, glycerine 20.5-21.0%, Brown Ferric Oxide 0.5-0.7%.
The propolis ganoderma lucidum soft capsule of health care is arranged, and the weight proportion of its filler component is: Ganodenna Lucidum P.E 16%, propolis extract 14%, soybean oil 65.5%, beeswax 4.5%; The weight proportion of its softgel shell component is: gelatin 41.4%, purified water 37.3%, glycerine 20.7%, Brown Ferric Oxide 0.6%.
The propolis ganoderma lucidum soft capsule that health care is arranged, the preparation method of propolis ganoderma lucidum soft capsule filler may further comprise the steps:
(1) assorts up-to-standard supplementary material by the prescription requirement, change in the clean area after checking, remove external packing;
(2) propolis extract, Ganodenna Lucidum P.E are crossed 100 mesh sieves respectively, subsequent use, propolis extract faces with facing with preceding deepfreeze and sieves;
(3) soybean oil of getting formula ratio drops into blend tank, adds the beeswax of formula ratio again, heat temperature raising to 70～80 ℃, and fusing stirs, and cooling must mix oil plant;
(4) propolis extract after will sieving, Ganodenna Lucidum P.E input are mixed in the oil plant and are mixed, and incorporation time 20 minutes is ground 2～3 times after colloid mill, vacuumize then and remove bubble, the soft capsule filler, subsequent use.
The propolis ganoderma lucidum soft capsule that health care is arranged, the preparation method of described propolis ganoderma lucidum soft capsule shell glue may further comprise the steps:
(1) with in the purified water of formula ratio, glycerine, Brown Ferric Oxide, the gelatin input glue jar successively;
(2) heat temperature raising to 70～80 ℃ while stirring are incubated 30 minutes;
(3) treat that gelatin all after the fusing, vacuumizes and removes bubble in the glue, cross 80 eye mesh screen plastic emittings, 50～60 ℃ of insulations are subsequent use.
The propolis ganoderma lucidum preparation of soft capsule method of health care is arranged, may further comprise the steps:
(1) under the environment of 18～26 ℃ of room temperatures, relative humidity 30～50%, the feed liquid and the softgel shell glue of content are put into respectively in the encapsulating machine, pelleting, the capsule and pill specification is the 0.5g/ grain;
(2) capsule and pill of producing came out of steamer through the supporting rolling cage type drying machine typing drying of encapsulating machine in 1～2 hour, evenly was positioned in the dry shallow bid, was temporarily stored between predry;
(3) the dried capsule and pill of typing is washed ball with 95% edible ethanol, and washing the rearmounted temperature of ball is 20～25 ℃, and relative humidity is under 25%～30% environment, after dry 24～48 hours, chooses ball, rejects special-shaped ball, defective works such as bubble or leakage of oil ball are arranged;
(4) qualified capsule and pill is sub-packed in the medicinal high-density polyethylene bottle of oral administration solid, every bottled 90, grab sample after the assay was approved, finished product vanning warehouse-in.
Characteristics of the present invention:
Propolis ganoderma lucidum soft capsule of the present invention has also increased and has improved body immunity and the function that reduces blood sugar except that the health care of the broad-spectrum antiseptic that has kept propolis, glossy ganoderma, anti-inflammatory and antalgic, the regeneration of promotion histocyte, antitumor, hepatic disease, treatment gastric ulcer, mouth disease, reduction triglyceride, cholesterol and adjusting blood sugar, insomnia and antidotal preventive and therapeutic effect.
The specific embodiment
Embodiment 1:
The weight proportion of its filler component of propolis ganoderma lucidum soft capsule is: Ganodenna Lucidum P.E 16%, propolis extract 14%, soybean oil 65.5%, beeswax 4.5%; The weight proportion of its softgel shell component is: gelatin 41.4%, purified water 37.3%, glycerine 20.7%, Brown Ferric Oxide 0.6%.
The preparation method of propolis ganoderma lucidum soft capsule filler may further comprise the steps:
(1) assorts up-to-standard supplementary material by the prescription requirement, change in the clean area after checking, remove external packing;
(2) propolis extract, Ganodenna Lucidum P.E are crossed 100 mesh sieves respectively, subsequent use, propolis extract faces with facing with preceding deepfreeze and sieves;
(3) soybean oil of getting formula ratio drops into blend tank, adds the beeswax of formula ratio again, heat temperature raising to 70～80 ℃, and fusing stirs, and cooling must mix oil plant;
(4) propolis extract after will sieving, Ganodenna Lucidum P.E input are mixed in the oil plant and are mixed; Incorporation time 20 minutes is ground 2～3 times after colloid mill, vacuumizes then that (vacuum 0.06～0.08Mpa) is removed bubble; Get the soft capsule filler, subsequent use.
The preparation method of propolis ganoderma lucidum soft capsule shell glue may further comprise the steps:
(1) with in the purified water of formula ratio, glycerine, Brown Ferric Oxide, the gelatin input glue jar successively;
(2) heat temperature raising to 70～80 ℃ while stirring are incubated 30 minutes;
(3) treat gelatin all after the fusing, vacuumize and remove bubble in the glue (vacuum 0.06～0.08Mpa) is crossed 80 eye mesh screen plastic emittings, and 50～60 ℃ of insulations are subsequent use.
The preparation method of propolis ganoderma lucidum soft capsule finished product may further comprise the steps:
(1) under the environment of 18～26 ℃ of room temperatures, relative humidity 30～50%, the feed liquid and the glue of content are put into respectively in the encapsulating machine, pelleting, the capsule and pill specification is the 0.5g/ grain;
(2) capsule and pill of producing came out of steamer through the supporting rolling cage type drying machine typing drying of encapsulating machine in 1～2 hour, evenly was positioned in the dry shallow bid, was temporarily stored between predry;
(3) the dried capsule and pill of typing is washed ball with 95% edible ethanol, and washing the rearmounted temperature of ball is 20～25 ℃, and relative humidity is under 25%～30% environment, after dry 24～48 hours, chooses ball, rejects special-shaped ball, defective works such as bubble or leakage of oil ball are arranged;
(4) qualified capsule and pill is sub-packed in the medicinal high-density polyethylene bottle of oral administration solid, every bottled 90, grab sample after the assay was approved, finished product vanning warehouse-in.
The present invention is as the clinical trial of auxiliary hyperglycemic:
With 100 routine hyperglycaemia volunteers, wherein test-meal group 50 examples, control group 50 examples; The test-meal group is taken propolis ganoderma lucidum capsule of the present invention; Viewing duration is former take the hypoglycemic medicine kind and dosage constant, before two groups of crowd's test-meals fasting blood sugars (FBG) and after the meal 2h blood glucose value (P2hBG) relatively, the difference not statistically significant; After taking 35 days; Fasting blood-glucose (FBG) on average descend difference and average rate of decrease, the test-meal group is respectively 0.98mmol/l and 9.33%, and control group is respectively-0.24mmol/l and-4.98%; On average descend difference and average rate of decrease of 2h blood sugar (P2hBG) after the meal, the test-meal group is respectively 1.83mmol/l and 16.37%, and control group is respectively-0.51 mmol/l and-6.29%.
Claims (5)
1. propolis ganoderma lucidum soft capsule that health care is arranged, it is characterized in that: the weight proportion of its filler component is: Ganodenna Lucidum P.E 15-17%, propolis extract 13-15%, soybean oil 64-67%, beeswax 4-5%; The weight proportion of its softgel shell component is: gelatin 41-42%, purified water 37-38%, glycerine 20.5-21.0%, Brown Ferric Oxide 0.5-0.7%.
2. the propolis ganoderma lucidum soft capsule that health care is arranged according to claim 1, it is characterized in that: the weight proportion of its filler component is: Ganodenna Lucidum P.E 16%, propolis extract 14%, soybean oil 65.5%, beeswax 4.5%; The weight proportion of its softgel shell component is: gelatin 41.4%, purified water 37.3%, glycerine 20.7%, Brown Ferric Oxide 0.6%.
3. the propolis ganoderma lucidum soft capsule that health care is arranged according to claim 1 is characterized in that: the preparation method of propolis ganoderma lucidum soft capsule filler may further comprise the steps:
(1) assorts up-to-standard supplementary material by the prescription requirement, change in the clean area after checking, remove external packing;
(2) propolis extract, Ganodenna Lucidum P.E are crossed 100 mesh sieves respectively, subsequent use, propolis extract faces with facing with preceding deepfreeze and sieves;
(3) soybean oil of getting formula ratio drops into blend tank, adds the beeswax of formula ratio again, heat temperature raising to 70～80 ℃, and fusing stirs, and cooling must mix oil plant;
(4) propolis extract after will sieving, Ganodenna Lucidum P.E input are mixed in the oil plant and are mixed, and incorporation time 20 minutes is ground 2～3 times after colloid mill, vacuumize then and remove bubble, the soft capsule filler, subsequent use.
4. the propolis ganoderma lucidum soft capsule that health care is arranged according to claim 1 is characterized in that: the preparation method of described propolis ganoderma lucidum soft capsule shell glue may further comprise the steps:
(1) with in the purified water of formula ratio, glycerine, Brown Ferric Oxide, the gelatin input glue jar successively;
(2) heat temperature raising to 70～80 ℃ while stirring are incubated 30 minutes;
(3) treat that gelatin all after the fusing, vacuumizes and removes bubble in the glue, cross 80 eye mesh screen plastic emittings, 50～60 ℃ of insulations are subsequent use.
5. the propolis ganoderma lucidum preparation of soft capsule method that health care is arranged as claimed in claim 1 is characterized in that may further comprise the steps:
(1) under the environment of 18～26 ℃ of room temperatures, relative humidity 30～50%, the feed liquid and the softgel shell glue of content are put into respectively in the encapsulating machine, pelleting, the capsule and pill specification is the 0.5g/ grain;
(2) capsule and pill of producing came out of steamer through the supporting rolling cage type drying machine typing drying of encapsulating machine in 1～2 hour, evenly was positioned in the dry shallow bid, was temporarily stored between predry;
(3) the dried capsule and pill of typing is washed ball with 95% edible ethanol, and washing the rearmounted temperature of ball is 20～25 ℃, and relative humidity is under 25%～30% environment, after dry 24～48 hours, chooses ball, rejects special-shaped ball, defective works such as bubble or leakage of oil ball are arranged;
(4) qualified capsule and pill is sub-packed in the medicinal high-density polyethylene bottle of oral administration solid, every bottled 90, grab sample after the assay was approved, finished product vanning warehouse-in.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210222521.2A CN102771786B (en) | 2012-06-29 | 2012-06-29 | Propolis and lucid ganoderma soft capsule with health care function and preparation method of propolis and lucid ganoderma soft capsule |
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| CN201210222521.2A CN102771786B (en) | 2012-06-29 | 2012-06-29 | Propolis and lucid ganoderma soft capsule with health care function and preparation method of propolis and lucid ganoderma soft capsule |
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| CN102771786A true CN102771786A (en) | 2012-11-14 |
| CN102771786B CN102771786B (en) | 2014-04-09 |
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| CN103815395A (en) * | 2013-12-25 | 2014-05-28 | 伊犁百信草原蜂业有限责任公司 | Propolis-safflower oil soft capsule and preparation method thereof |
| CN104000198A (en) * | 2014-06-13 | 2014-08-27 | 上海赫尔伯生物科技有限公司 | Compound capsules with kidney nourishing, essence replenishing, vitality invigorating and yang tonifying functions and preparation method thereof |
| CN104920933A (en) * | 2015-06-09 | 2015-09-23 | 江苏日高蜂产品有限公司 | Propolis soft capsules and preparation method thereof |
| CN106262790A (en) * | 2016-08-30 | 2017-01-04 | 开平健之源保健食品有限公司 | A kind of soft capsule of glossy ganoderma and preparation method thereof |
| CN106262990A (en) * | 2016-08-08 | 2017-01-04 | 江苏江大源生态生物科技股份有限公司 | A kind of astragalus polysaccharides selenium-rich capsule and preparation method thereof |
| CN106361790A (en) * | 2016-08-26 | 2017-02-01 | 湖北新阳蜂业有限公司 | Bee propolis capsule and preparation method thereof |
| CN108743744A (en) * | 2018-08-03 | 2018-11-06 | 东营广元生物科技股份有限公司 | A kind of bluish dogbane bee glue soft capsule and preparation method thereof |
| AU2017200872B2 (en) * | 2014-03-10 | 2019-01-31 | Paul Edward Stamets | Integrative fungal solutions for protecting bees |
| CN109329835A (en) * | 2018-12-05 | 2019-02-15 | 天津铸源健康科技集团有限公司 | A kind of bee glue soft capsule and preparation method thereof |
| CN110025685A (en) * | 2019-05-07 | 2019-07-19 | 王艳军 | A kind of composition liquid preparation containing propolis |
| CN110623261A (en) * | 2019-10-14 | 2019-12-31 | 安徽萨普丽生物医药有限公司 | Lucid ganoderma propolis capsule and preparation method thereof |
| US10813960B2 (en) | 2000-10-04 | 2020-10-27 | Paul Edward Stamets | Integrative fungal solutions for protecting bees and overcoming colony collapse disorder (CCD) |
| CN112076225A (en) * | 2020-09-27 | 2020-12-15 | 安徽鑫全康药业有限公司 | Ganoderma lucidum propolis soft capsule |
| CN115154583A (en) * | 2022-07-07 | 2022-10-11 | 北京美宝高科技有限责任公司 | Capsule for promoting gastrointestinal mucosa self-repair and protecting gastrointestinal function and preparation method thereof |
| CN115350245A (en) * | 2022-09-23 | 2022-11-18 | 晨日药业(辽宁)有限责任公司 | Composition with function of delaying senescence and preparation method thereof |
| US11752182B2 (en) | 2014-03-10 | 2023-09-12 | Turtle Bear Holdings, Llc | Integrative fungal solutions for protecting bees |
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| CN102488718A (en) * | 2011-12-27 | 2012-06-13 | 深圳市麦金利实业有限公司 | Fish oil soft capsule and its preparation method |
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| US10821145B2 (en) | 2000-10-04 | 2020-11-03 | Paul E. STAMETS | Integrative fungal solutions for protecting bees |
| US10813960B2 (en) | 2000-10-04 | 2020-10-27 | Paul Edward Stamets | Integrative fungal solutions for protecting bees and overcoming colony collapse disorder (CCD) |
| CN103815395A (en) * | 2013-12-25 | 2014-05-28 | 伊犁百信草原蜂业有限责任公司 | Propolis-safflower oil soft capsule and preparation method thereof |
| AU2017200872B2 (en) * | 2014-03-10 | 2019-01-31 | Paul Edward Stamets | Integrative fungal solutions for protecting bees |
| US11752182B2 (en) | 2014-03-10 | 2023-09-12 | Turtle Bear Holdings, Llc | Integrative fungal solutions for protecting bees |
| CN104000198B (en) * | 2014-06-13 | 2016-03-23 | 上海赫尔伯生物科技有限公司 | A kind of have kidney tonifying, essence replenishing, the emerging positive compound capsule acted on of benefit god and preparation method thereof |
| CN104000198A (en) * | 2014-06-13 | 2014-08-27 | 上海赫尔伯生物科技有限公司 | Compound capsules with kidney nourishing, essence replenishing, vitality invigorating and yang tonifying functions and preparation method thereof |
| CN104920933A (en) * | 2015-06-09 | 2015-09-23 | 江苏日高蜂产品有限公司 | Propolis soft capsules and preparation method thereof |
| CN106262990A (en) * | 2016-08-08 | 2017-01-04 | 江苏江大源生态生物科技股份有限公司 | A kind of astragalus polysaccharides selenium-rich capsule and preparation method thereof |
| CN106361790A (en) * | 2016-08-26 | 2017-02-01 | 湖北新阳蜂业有限公司 | Bee propolis capsule and preparation method thereof |
| CN106262790A (en) * | 2016-08-30 | 2017-01-04 | 开平健之源保健食品有限公司 | A kind of soft capsule of glossy ganoderma and preparation method thereof |
| CN108743744A (en) * | 2018-08-03 | 2018-11-06 | 东营广元生物科技股份有限公司 | A kind of bluish dogbane bee glue soft capsule and preparation method thereof |
| CN109329835A (en) * | 2018-12-05 | 2019-02-15 | 天津铸源健康科技集团有限公司 | A kind of bee glue soft capsule and preparation method thereof |
| CN110025685A (en) * | 2019-05-07 | 2019-07-19 | 王艳军 | A kind of composition liquid preparation containing propolis |
| CN110025685B (en) * | 2019-05-07 | 2021-08-17 | 王艳军 | A liquid preparation containing propolis composition |
| CN110623261A (en) * | 2019-10-14 | 2019-12-31 | 安徽萨普丽生物医药有限公司 | Lucid ganoderma propolis capsule and preparation method thereof |
| CN112076225A (en) * | 2020-09-27 | 2020-12-15 | 安徽鑫全康药业有限公司 | Ganoderma lucidum propolis soft capsule |
| CN115154583A (en) * | 2022-07-07 | 2022-10-11 | 北京美宝高科技有限责任公司 | Capsule for promoting gastrointestinal mucosa self-repair and protecting gastrointestinal function and preparation method thereof |
| CN115350245A (en) * | 2022-09-23 | 2022-11-18 | 晨日药业(辽宁)有限责任公司 | Composition with function of delaying senescence and preparation method thereof |
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