CN102763729A - Composite bovine colostrum powder for improving bone mineral density - Google Patents
Composite bovine colostrum powder for improving bone mineral density Download PDFInfo
- Publication number
- CN102763729A CN102763729A CN2012102397346A CN201210239734A CN102763729A CN 102763729 A CN102763729 A CN 102763729A CN 2012102397346 A CN2012102397346 A CN 2012102397346A CN 201210239734 A CN201210239734 A CN 201210239734A CN 102763729 A CN102763729 A CN 102763729A
- Authority
- CN
- China
- Prior art keywords
- powder
- bovine colostrum
- compound
- micro
- colostrum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The invention discloses a composite bovine colostrum powder for improving bone mineral density. The formula is that each 100g of the composite bovine colostrum powder comprises 37-45g of bovine colostrum powder, 15-22g of chitosan powder, 11-19g of ossein albumen powder, 7-14g of calcium acetate and 0.014-0.018g of vitamin D3 micro-capsule powder (500 thousand IU/g), and the balance of defatted milk powder. Compared with the prior art, the composite bovine colostrum powder for modifying the retrogressive osteoporosis and improving the bone mineral density, provided by the scheme of the invention, belongs to the health-care products; after being used, the bovine colostrum powder has no toxic or side effects; and the composite bovine colostrum powder has the functions of conditioning the immune level of a human body, improving the acid-base balance of the human body, replenishing the organic acid calcium, enhancing the calcium absorption, increasing the osteogenesis level and the like, and is particularly applicable for being taken by patients of retrogressive osteoporosis.
Description
Technical field
The invention belongs to the health food technology field, be specifically related to a kind of compound bovine colostrum.
Background technology
Contain extremely abundant bioactivator in the colostrum, like immune factor and growth factor.The content of the immune factor in the colostrum be normal Ruzhong 5-10 doubly, also be one of the living resources of intensive immune factor of occurring in nature, the para-insulin sex factor and the EGF that are rich in the colostrum, obvious to the facilitation of tissue growth.Through scientific experiment proof colostrum and goods thereof immunological regulation arranged, improve enteron aisle, in and enterotoxin, promotion grow, delay senility, suppress a series of physiological functions such as multiple germ, control agent inner equilibrium.
Along with the increase of China's elderly population, osteoporosis (osteoporosls) incidence of disease is in ascendant trend.The degeneration osteoporosis is a kind of physiological osteoporosis pathology that takes place with the growth at age.The degeneration osteoporosis shows as: the bone amount reduces, the microstructure degeneration of bone, and the fragility of bone increases and is easy to fracture.The degeneration osteoporosis is the basic law of skeleton development, growth, aging, causes that the reason of this disease is a lot, and wherein the shortage of calcium is the factor of generally acknowledging.Along with the development of medical science and going deep into to osteoporosis research; Increasing research confirms; For keeping the acid-base balance of body fluid in the body; Health can be employed in the alkaline matter and acidic materials, and calcareous be the maximum alkaline matter of in-vivo content, acidic constitution is calcium loss, osteoporotic major reason.Whether osteoporosis suffers from the influence of many aspects factors such as also receiving immune state (whole body physique, disease), nutrition condition, hormone control level, gene, life style, motion mode, health care.If can strengthen health care consciousness early, carry out the science intervention, the degeneration osteoporosis possibly delay and prevent.The important indicator of osteoporosis is considered in the bone density conduct, the improvement of the raising meaning osteoporosis of bone density level.
The present colostrum product of exploitation, product component and function are single relatively, the most focus utilization of product development the immunological characteristic of colostrum, and other active constituent is not fully utilized effectively.
Based on this, be necessary to develop a kind of compound bovine colostrum, to improve immunity, increase bone density, and improve osteoporosis.
Summary of the invention
In order to solve the problems referred to above that exist in the prior art, further utilize colostrum to regulate human body basis balance, improve the characteristic of immunocompetence, improve bone density, improve osteoporosis, the present invention proposes a kind of compound bovine colostrum that improves bone density.
The present invention is beneficial to Ruzhong active factors just, regulates immunity, regulates isohydria, the shitosan of auxiliary improvement physique acid-base balance; Preparation high-quality calcium source and the component that promotes that calcium absorbs, calcium adheres to; Form one group of compound bovine colostrum that improves bone density, concrete technical scheme is following
A kind of compound bovine colostrum that improves bone density; Its prescription is that this compound bovine colostrum of every 100g comprises: bovine colostrum 37-45g, chitosan powder 15-22g; Bone collagen powder 11-19g; Calcium acetate 7-14g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.014-0.018g, surplus is a skimmed milk power.
In this prescription, bovine colostrum is the vacuum freeze drying powder; Shitosan is the bake drying powder; Bone collagen powder is the enzymolysis spray dried powder; Cholecalciferol micro-capsule powder is 100% xeraphium through 40 mesh standard sieves.
The main component of shitosan described in the above-mentioned compound bovine colostrum is the derivative behind the chitin deacetylase base, and chitin is the straight-chain polysaccharide of N-acetyl group-D-pyran glucosamine polymerization.
Said bone collagen is the product of corium fabric cell enzymolysis.
Said calcium acetate ［ (CH
3COO)
2CaH
2O ］ calcium content be 25%, absorptivity is 32%.
The optimization formula scheme of a kind of compound bovine colostrum that improves bone density of the present invention is following:
Prescription 1: the compound bovine colostrum of every 100g contains bovine colostrum 37g, chitosan powder 22g, and bone collagen powder 13g, calcium acetate 7g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.014g, surplus is a skimmed milk power.
Prescription 2: the compound bovine colostrum of every 100g contains bovine colostrum 39g, chitosan powder 15g, and bone collagen powder 15g, calcium acetate 14g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.018g, surplus is a skimmed milk power.
Prescription 3: the compound bovine colostrum of every 100g contains bovine colostrum 41g, chitosan powder 21g, and bone collagen powder 11g, calcium acetate 9g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.015g, surplus is a skimmed milk power.
Prescription 4: the compound bovine colostrum of every 100g contains bovine colostrum 43g, chitosan powder 19g, and bone collagen powder 17g, calcium acetate 12g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.016g, surplus is a skimmed milk power.
Prescription 5: the compound bovine colostrum of every 100g contains bovine colostrum 37g, chitosan powder 17g, and bone collagen powder 19g, calcium acetate 13g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.017g, surplus is a skimmed milk power.
Prescription 6: every 100g is compound, and bovine colostrum comprises: bovine colostrum 45g, and chitosan powder 15g, bone collagen powder 19g, calcium acetate 14g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.018g, surplus is a skimmed milk power.
In this compound bovine colostrum, used skimmed milk power be with fresh milk through degreasing, concentrate, powdery product that drying is processed, wherein fat has been reduced to 1%.
Compared with prior art; The compound bovine colostrum that improves degeneration osteoporosis, raising bone density that the present invention program provides belongs to health products, uses the back that human body is not had toxic and side effect; And this compound bovine colostrum has the human body of adjusting immune level, improves the health acid-base balance; Replenish calcium of organic acid, strengthen calcium and absorb, improve effects such as skeletonization level, be fit to very much the degeneration patients with osteoporosis and take.
The specific embodiment
Below in conjunction with specific embodiment the present technique scheme is further specified as follows:
A kind of compound bovine colostrum that improves bone density; Its prescription is that this compound bovine colostrum of every 100g comprises: bovine colostrum 37-45g, chitosan powder 15-22g; Bone collagen powder 11-19g; Calcium acetate 7-14g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.014-0.018g, surplus is a skimmed milk power.In this prescription, bovine colostrum is the vacuum freeze drying powder; Shitosan is the bake drying powder; Bone collagen powder is the enzymolysis spray dried powder; Cholecalciferol micro-capsule powder is 100% xeraphium through 40 mesh standard sieves.
Embodiment 1
A kind of compound bovine colostrum that improves bone density, the compound bovine colostrum of every 100g contains bovine colostrum 37g in its prescription, chitosan powder 22g, bone collagen powder 13g, calcium acetate 7g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.014g, surplus is a skimmed milk power.
Embodiment 2
A kind of compound bovine colostrum that delays the degeneration osteoporosis, the compound bovine colostrum of every 100g contains bovine colostrum 39g, chitosan powder 15g in its prescription; Bone collagen powder 15g; Calcium acetate 14g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.018g, surplus is a skimmed milk power.
Embodiment 3
A kind of compound bovine colostrum that improves bone density, the compound bovine colostrum of every 100g contains bovine colostrum 41g in its prescription, chitosan powder 21g, bone collagen powder 11g, calcium acetate 9g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.015g, surplus is a skimmed milk power.
Embodiment 4
A kind of compound bovine colostrum that improves bone density, the compound bovine colostrum of every 100g contains bovine colostrum 43g in its prescription, chitosan powder 19g, bone collagen powder 17g, calcium acetate 12g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.016g, surplus is a skimmed milk power.
Embodiment 5
A kind of compound bovine colostrum that improves bone density, the compound bovine colostrum of every 100g contains bovine colostrum 37g in its prescription, chitosan powder 17g, bone collagen powder 19g, calcium acetate 13g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.017g, surplus is a skimmed milk power.
Embodiment 6
A kind of compound bovine colostrum that improves bone density, the compound bovine colostrum of every 100g comprises in its prescription: bovine colostrum 45g, chitosan powder 15g; Bone collagen powder 19g; Calcium acetate 14g, cholecalciferol micro-capsule powder (500,000 IU/g) 0.018g, surplus is a skimmed milk power.
Among the above embodiment, the colostrum freeze-dried powder is that milk cow produces the milk in back 48 hours, after PROCESS FOR TREATMENT such as clean breast, film degerming, multistage membrane microfiltration, obtains active factors stoste, again the product after vacuum freeze drying.Colostrum freeze-dried powder height has kept active immune globulin (IGg), lactoferrin (LF) and each growth factor isoreactivity material in first Ruzhong.G type globulin wherein accounts for more than 70% of immune protein total amount, is to reply the most lasting, most important antibody in the colostrum immune, in anti-infective, plays main force; IgA, IgM have the Respirovirus of slowing down breeding respectively, sterilization, bacteriolyze, engulf, effect such as aggegation.Just immune factor and other component in Ruzhong have determined colostrum and products thereof to have and have regulated function immune, that improve multinomial special physiologicals such as intestinal absorption, control agent inner equilibrium.
Utilize this compound bovine colostrum to improve the experiment of the big white mouse of bone density, specific as follows:
One, experimental technique
1, the Kunming big white mouse of selecting Nanjing University mouse experiment center to provide, requirement is about 20 ages in days, body weight 55g, each 16 of male and female; Principle by random sampling; Be divided into two groups each 16, every group of male and female half and half are confirmed experimental group and control group (model group) by randomized.
2, cause the osteoporosis test, the white mouse of experimental group and control group is pressed 60mg/kg.d equally, once a day, perfusion dimension A acid, continuous 15 days.
3, the feed mouse grain of same recipe of two groups of big white mouse is fed by 4g/100g body weight (24 hours) standard, gives supplementary feeding to experimental group and control group simultaneously, the compound colostrum powder and the whole milk powder of use-case 1 prescription respectively, and the supplementary feeding amount is the 2mg/100g body weight.
4, the mouse safety test of feeding.
Two, mensuration project and method:
(1) mensuration project
1, measures the rat serum calcium content, 2, measure the rat bone density level.
(2) assay method
At the 16th day, the 31st day, the 61st day of the experiment beginning, measure rat blood calcium and level of density respectively.
Hitachi-T600 automatic clinical chemistry analyzer is adopted in blood calcium determination, obtains the blood calcium value; Bone density detects and adopts micro-CT to measure right side DF cancellous bone and cortex bone microstructure parameters, and X line borne densitometers (DXA) is measured the left side femoral bmd.
Three, statistical analysis experimental data is used method of analysis of variance, F check comparative group differences property.
Four, experimental result shows:
1, at the 16th day of experiment day, the blood calcium average level of two groups of rats was respectively experimental group (1.97 ± 0.05) mmol/L and control group (1.97 ± 0.08) mmol/L;
The 31st day, experimental group mean value (2.21 ± 0.06) mmol/L control group (2.17 ± 0.06) mmol/L;
The 61st day, experimental group mean value (2.51 ± 0.08) mmol/L, control group (2.20 ± 0.05) mmol/L.
In experiment the 16th day the time, two groups of calcium levels much at one, no significant difference.In the time of the 31st day, the experimental group calcium level reaches lower limits of normal, and control group is lower than normal value.In the time of the 61st day, the experimental group calcium level is in the medium level on the upper side of normal range (NR), and control group is a little less than normal value, and difference is extremely remarkable.
2, at experiment day the 16th day and measurement rat bone density on the 61st, experiment day two groups of overall bone density levels on the 16th do not have the statistics gap, and VBMD is-2.5SD; In the time of 61 days, the experimental group bone density is VBMD+1SD, and control group is that VBMD is-2.0SD.
In the time of the 61st day, the VBMD of experimental group and the BMC of experimental group have strong correlation, and coefficient correlation is 0.944; The male and female mouse X sheet of experimental group shows that the drug-induced osteoporosis has the improvement of obviously becoming better.
3,30 days feeding experiments show, mix the compound colostrum powder that instance 1 is filled a prescription by 50mg/100g and 100mg/100g b.w in the basal feed, and this sample does not have obvious illeffects to big white mouse each item index, and the NOAEL value of feeding in 30 days is 180mg/100g.
Equally; Prescription in the use-case 2～6 experimentizes respectively; Can obtain similar conclusion equally: these article use the back that small white mouse is not had toxic and side effect; This compound bovine colostrum has the immunity of organism of adjusting level, improves the health acid-base balance, replenishes calcium of organic acid, strengthens the effects such as level of calcium absorption, skeletonization.
Claims (8)
1. compound bovine colostrum that improves bone density; It is characterized in that its prescription is: the compound bovine colostrum of every 100g contains bovine colostrum 37-45g; Chitosan powder 15-22g, bone collagen powder 11-19g, calcium acetate 7-14g; Cholecalciferol micro-capsule powder (500,000 IU/g) 0.014-0.018g, surplus is a skimmed milk power.
2. a kind of compound bovine colostrum that improves bone density according to claim 1 is characterized in that bovine colostrum is the vacuum freeze drying powder; Shitosan is the bake drying powder; The bone collagen powder is the enzymolysis spray dried powder; Cholecalciferol micro-capsule powder is 100% xeraphium through 40 mesh standard sieves.
3. a kind of compound bovine colostrum that improves bone density according to claim 1 and 2; It is characterized in that its prescription is: the compound bovine colostrum of every 100g contains bovine colostrum 37g; Chitosan powder 22g, bone collagen powder 13g, calcium acetate 7g; Cholecalciferol micro-capsule powder (500,000 IU/g) 0.014g, surplus is a skimmed milk power.
4. a kind of compound bovine colostrum that improves bone density according to claim 1 and 2; It is characterized in that its prescription is: the compound bovine colostrum of every 100g contains bovine colostrum 39g; Chitosan powder 15g, bone collagen powder 15g, calcium acetate 14g; Cholecalciferol micro-capsule powder (500,000 IU/g) 0.018g, surplus is a skimmed milk power.
5. a kind of compound bovine colostrum that improves bone density according to claim 1 and 2; It is characterized in that its prescription is: the compound bovine colostrum of every 100g contains bovine colostrum 41g; Chitosan powder 21g, bone collagen powder 11g, calcium acetate 9g; Cholecalciferol micro-capsule powder (500,000 IU/g) 0.015g, surplus is a skimmed milk power.
6. a kind of compound bovine colostrum that improves bone density according to claim 1 and 2; It is characterized in that its prescription is: the compound bovine colostrum of every 100g contains bovine colostrum 43g; Chitosan powder 19g, bone collagen powder 17g, calcium acetate 12g; Cholecalciferol micro-capsule powder (500,000 IU/g) 0.016g, surplus is a skimmed milk power.
7. a kind of compound bovine colostrum that improves bone density according to claim 1 and 2; It is characterized in that its prescription is: the compound bovine colostrum of every 100g contains bovine colostrum 37g; Chitosan powder 17g, bone collagen powder 19g, calcium acetate 13g; Cholecalciferol micro-capsule powder (500,000 IU/g) 0.017g, surplus is a skimmed milk power.
8. a kind of compound bovine colostrum that improves bone density according to claim 1 and 2; It is characterized in that its prescription is: the compound bovine colostrum of every 100g contains bovine colostrum 45g; Chitosan powder 15g, bone collagen powder 19g, calcium acetate 14g; Cholecalciferol micro-capsule powder (500,000 IU/g) 0.018g, surplus is a skimmed milk power.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210239734 CN102763729B (en) | 2012-07-11 | 2012-07-11 | Composite bovine colostrum powder for improving bone mineral density |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210239734 CN102763729B (en) | 2012-07-11 | 2012-07-11 | Composite bovine colostrum powder for improving bone mineral density |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102763729A true CN102763729A (en) | 2012-11-07 |
| CN102763729B CN102763729B (en) | 2013-09-04 |
Family
ID=47091493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210239734 Expired - Fee Related CN102763729B (en) | 2012-07-11 | 2012-07-11 | Composite bovine colostrum powder for improving bone mineral density |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102763729B (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104026239A (en) * | 2014-06-26 | 2014-09-10 | 光明乳业股份有限公司 | Bone-strengthened milk and preparation method thereof |
| CN104939098A (en) * | 2014-03-26 | 2015-09-30 | 营养屋(成都)生物医药有限公司 | Health food capable of enhancing bone immunity and supplementing and locking calcium and preparation method of health food |
| US20160296567A1 (en) * | 2013-12-02 | 2016-10-13 | Julius-Maximilians-Universität Würzburg | Pharmaceutical composition for the prophylaxis and/or treatment of diseases in which LPS- and/or apoptosis regulation is disturbed |
| CN110720515A (en) * | 2019-10-25 | 2020-01-24 | 李玉保 | Bone collagen polypeptide composite nutrient for improving bone mineral density and preparation method thereof |
| RU2726438C2 (en) * | 2018-11-14 | 2020-07-14 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СтГМУ Минздрава России) | Method for production of a dry high protein milk mixture for prevention of osteopenia in children and adolescents with gee's disease |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1413596A (en) * | 2002-03-16 | 2003-04-30 | 赵伟洁 | Yoghurt containing ossein protein capsule, chewing tablet and its preparation method |
| US20030124198A1 (en) * | 1998-06-10 | 2003-07-03 | Albert Crum | Nutritional or therapeutic supplement and method |
| CN101213992A (en) * | 2007-12-28 | 2008-07-09 | 内蒙古伊利实业集团股份有限公司 | Bone strengthening milk powder and producing method thereof |
| CN101695318A (en) * | 2009-09-14 | 2010-04-21 | 蔡晓东 | Milk calcium tablet |
-
2012
- 2012-07-11 CN CN 201210239734 patent/CN102763729B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030124198A1 (en) * | 1998-06-10 | 2003-07-03 | Albert Crum | Nutritional or therapeutic supplement and method |
| CN1413596A (en) * | 2002-03-16 | 2003-04-30 | 赵伟洁 | Yoghurt containing ossein protein capsule, chewing tablet and its preparation method |
| CN101213992A (en) * | 2007-12-28 | 2008-07-09 | 内蒙古伊利实业集团股份有限公司 | Bone strengthening milk powder and producing method thereof |
| CN101695318A (en) * | 2009-09-14 | 2010-04-21 | 蔡晓东 | Milk calcium tablet |
Non-Patent Citations (2)
| Title |
|---|
| 李新玲等: "活性牛初乳钙片的研制与生产", 《中国乳业》 * |
| 李晓东等: "儿童营养酸奶的研制", 《中国供销商情.乳业导刊》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160296567A1 (en) * | 2013-12-02 | 2016-10-13 | Julius-Maximilians-Universität Würzburg | Pharmaceutical composition for the prophylaxis and/or treatment of diseases in which LPS- and/or apoptosis regulation is disturbed |
| US10350244B2 (en) * | 2013-12-02 | 2019-07-16 | Martin Gasser | Pharmaceutical composition for the treatment of diseases in which LPS- and/or apoptosis regulation is disturbed |
| CN104939098A (en) * | 2014-03-26 | 2015-09-30 | 营养屋(成都)生物医药有限公司 | Health food capable of enhancing bone immunity and supplementing and locking calcium and preparation method of health food |
| CN104026239A (en) * | 2014-06-26 | 2014-09-10 | 光明乳业股份有限公司 | Bone-strengthened milk and preparation method thereof |
| RU2726438C2 (en) * | 2018-11-14 | 2020-07-14 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СтГМУ Минздрава России) | Method for production of a dry high protein milk mixture for prevention of osteopenia in children and adolescents with gee's disease |
| CN110720515A (en) * | 2019-10-25 | 2020-01-24 | 李玉保 | Bone collagen polypeptide composite nutrient for improving bone mineral density and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102763729B (en) | 2013-09-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102763729B (en) | Composite bovine colostrum powder for improving bone mineral density | |
| CN111602720A (en) | Formula milk powder for middle-aged and old people | |
| MXPA99008953A (en) | Nutritional formulations containing oligosaccharides | |
| CN103039976A (en) | Healthcare food for increasing bone density and preparation method thereof | |
| Mehaba et al. | Heat stress affects some physiological and productive variables and alters metabolism in dairy ewes | |
| EP4164414A1 (en) | Nutritional formula | |
| US11701404B2 (en) | Human milk fortifier composition | |
| WO2013008155A1 (en) | Therapeutic composition and uses thereof | |
| CN105079028A (en) | Health care product capable of improving bones and joints and preparation method of health care product | |
| CN107494963A (en) | Pet calcium cream and preparation method thereof | |
| CN101279089B (en) | Donkey-hide gelatin calcium composition and preparing process thereof | |
| Kruger et al. | Postprandial metabolic responses of serum calcium, parathyroid hormone and C-telopeptide of type I collagen to three doses of calcium delivered in milk | |
| KR101388395B1 (en) | Composition for improving nutritional status, reducing frequency of fever and/or increasing immunocompetence of elderly | |
| CN108703378A (en) | A kind of fro diabetic many polymerizers of the EA | |
| CN102018220A (en) | CPP (Casein Phospho Peptides) protein powder food and processing process thereof | |
| WO2023241110A1 (en) | Nutritional composition, food comprising same, and use of nutritional composition | |
| CN103211228A (en) | Composition for increasing bone mineral density | |
| Rashid et al. | Studies on the nutritional composition of goat (Beetal) colostrum and its mature milk | |
| CN101152188B (en) | Vitamin D* solid dispersion peridium patch and method for preparing the same | |
| US20220054514A1 (en) | Human milk fortifier composition | |
| Geddes et al. | 7 Human Milk: Bioactive Components and Their Effects on the Infant and Beyond | |
| CN104939098A (en) | Health food capable of enhancing bone immunity and supplementing and locking calcium and preparation method of health food | |
| CN103976216A (en) | Health-protection product with functions of supplementing calcium and enhancing immunity and preparation method for health-protection product | |
| KR20040085848A (en) | Method for producing honey of high functional and high quality | |
| CN109645486A (en) | A kind of effective prescription and preparation method for supplementing maternal nutritional and promoting infants growth and development |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130904 Termination date: 20170711 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |