CN102755623A - Medicine for treating acute gastroenteritis and preparation method thereof - Google Patents
Medicine for treating acute gastroenteritis and preparation method thereof Download PDFInfo
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- CN102755623A CN102755623A CN2012102790034A CN201210279003A CN102755623A CN 102755623 A CN102755623 A CN 102755623A CN 2012102790034 A CN2012102790034 A CN 2012102790034A CN 201210279003 A CN201210279003 A CN 201210279003A CN 102755623 A CN102755623 A CN 102755623A
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Abstract
The invention relates to medicine for treating acute gastroenteritis and a preparation method thereof. The medicine is composed of 17 species of traditional Chinese medicine including kudzu vine root, agastache rugosus, rhizoma atractylodis, fructus amomi and the like. The dosage form of the medicine includes oral liquid, capsule, tablet and the like. The acute gastroenteritis is an acute gastrointestinal tract disease caused by various reasons including bacteria, virus, chemical drugs, residual pesticide, impure deteriorating toxic food, intemperance, engorgement and the like. Symptoms appear within 24 hours in most time. Main clinical features includes midsection discomfort, stomachache, bellyache, turgor, nausea, vomiting, diarrhea, watery stool and even paroxysmal gastrointestinal colic. Severely, patients have nausea, vomit, have diarrhea continuously and quickly have the critical symptoms of dehydration, acidosis, shock, exhaustion, collapse and the like. The treating principle of the acute gastroenteritis includes coursing the exterior, scattering cold, clearing heat and dampness, warming the middle, strengthening the spleen and the stomach, regulating vital energy and facilitating urination. The prescription of the medicine is formed by summarizing clinical practices in long time, no similar pure traditional Chinese medicine exists in the existing documents by search, and the medicine is a practical medicament for first aid for clinical use, household use and travel use.
Description
One, technical field:
The present invention is a kind of medicine of treating acute gastroenteritis and preparation method thereof, belongs to tcm field.
Two, background technology
Acute gastroenteritis is the acute gastroenteropathy that is caused by multiple factors such as antibacterial, virus, chemicals, residual pesticide, unclean rotten poisonous food, excessive drinking, eating and drinking too much at one meal; General how in 24h, the morbidity; Main clinical manifestation is: epigastric discomfort, stomachache, stomachache, distension, nausea and vomiting, diarrhoea watery stool, and very then paroxysmal gastrointestinal angor exactly likes typhlitic bottom right abdomen severe pain; Serious nausea and vomiting; Acute diarrhea is more than, rushes down the back pain relief, occurs critical symptoms such as dehydration, acidosis, shock, depletion, collapse very soon.
Primary disease all can take place throughout the year, but with spring, summer, early autumn weather warm, the rain Sheng that wet, heat-damp in summer is invaded gastrointestinal; And damp and hotly accumulate steaming, favourable bacterial virus grows breeding very soon, and food, vegetable, fruit is easy to go bad, again because weather is hot; Eating cold and uncooked food excessively melon and fruit, or the greedy cool wind of working as, low-temperature air conditioner, fan etc. causes wind and cold invasion and attack, impairing the spleen and stomach intestinal internal organs yang-energy; Cause dyspepsia not changed, dysfunction of the spleen in transportation and transformation, and acute gastrointestinal disease appears.
(medicine) being taken before meal is with bigcatkin willow acids antipyretic analgesic, Operand, sulfonamides, metronidazole, ofloxacin class antibiotic medicine, and prednisone class medicine, spirits and maror too, parlkaline, peracidity food all very easily cause the acute gastroenteritis disease.
Mostly the pathogenic bacterium of primary disease are Salmonella or Halobacterium, bacteriotoxin with staphylococcus aureus, colitoxin for seeing more, Causative virus with rotavirus, mycete or protozoon viral infection for seeing more.
Acute gastroenteritis belongs to sick categories such as traditional Chinese medical science vomiting, stomachache, diarrhoea, and its cause of disease is comparatively complicated:
1, unhygienic diet: eat poisonous food by mistake, the pesticide residues vegetables and fruits, rotten food damages gastrointestinal function very soon, causes the taste abnormal ascending-descending of QI, clear QI being mixed up with turbid QI, functional activity of QI being not smooth forms primary disease.
2, diseases caused by exogenous pathogenic factor cold-damp is invaded gastrointestinal in the damp and hot heresy, is stranded the resistance taste, spleen preferring dryness to dampness; Pathogenic factor impairing the spleen and stomach yang-energies such as cold, wet, heat, turbid damp is handed over burnt mechanism of qi in the resistance, clear QI being mixed up with turbid QI; Superinverse and be gastropathy vomiting, suffering from diarrhoea appears in strongly fragrant resistance intestinal and stomachache occurs, mix and descend; The exterior tightened by exogenous pathogens and have fever with chills, headache dusk heavy, the whole body sleepiness is unable, and loss of appetite is detested symptoms such as greasy.
3, (medicine) being taken before meal is used the chemicals that gastrointestinal mucosa is stimulated damage; Pungent, spirits, raw and cold melon and fruit, or eating and drinking too much at one meal impairing the spleen and stomach cause gastrointestinal dysfunction; Mucous hyperemia inflammation and violent nausea and vomiting, stomachache, stomachache, distension occur, the more than serious symptoms of diarrhoea watery stool.
According to the sick position of primary disease, the cause of disease, pathogenesis and clinical symptoms thereof, its Therapeutic Principle is the relieving the exterior syndrome cold expelling, Qinghua is damp and hot, warming middle-JIAO and strengthening the spleen stomach function regulating, regulating functional activities of qi dampness removing.
Three, summary of the invention:
1, medicine of the present invention and weight proportion thereof are:
Radix Puerariae 20-50 part, windproof 15-50 part, Radix Angelicae Dahuricae 15-40 part, Herba Pogostemonis 15-50 part, Rhizoma Atractylodis 20-60 part, Radix Scutellariae 20-50 part, Rhizoma Pinelliae 20-50 part, Pericarpium Citri Reticulatae 10-40 part, Poria 20-60 part, Fructus Amomi 10-40 part, Fructus Amomi Rotundus 10-30 part, Fructus Aurantii Immaturus 10-30 part Radix Linderae 10-40 part, Cortex Magnoliae Officinalis 10-40 part, Rhizoma Zingiberis 10-40 part, Radix Paeoniae Alba 15-50 part, Radix Glycyrrhizae 10-30 part.
2, the preferred weight proportioning of medicine of the present invention is:
Radix Puerariae 15-50 part, windproof 15-50 part, Radix Angelicae Dahuricae 10-40 part, Herba Pogostemonis 15-50 part, Rhizoma Atractylodis 15-60 part, Radix Scutellariae 15-50 part, Rhizoma Pinelliae 15-50 part, Pericarpium Citri Reticulatae 10-30 part, Poria 20-50 part, Fructus Amomi 10-30 part, Fructus Amomi Rotundus 10-30 part, Fructus Aurantii Immaturus 10-30 part Radix Linderae 10-30 part, Cortex Magnoliae Officinalis 10-30 part, Rhizoma Zingiberis 10-40 part, Radix Paeoniae Alba 15-40 part, Radix Glycyrrhizae 10-30 part.
3, the optimum weight proportioning of medicine of the present invention is:
40 parts of Radix Puerariaes, windproof 30 parts, 30 parts of the Radixs Angelicae Dahuricae, 40 parts of Herba Pogostemoniss, 50 parts of Rhizoma Atractylodis, 40 parts of Radix Scutellariaes, 50 parts of the Rhizoma Pinelliaes, 30 parts of Pericarpium Citri Reticulataes, 50 parts in Poria, 30 parts of Fructus Amomis, 20 parts of Fructus Amomi Rotunduss, 15 parts of Fructus Aurantii Immaturuss, 20 parts of the Radixs Linderae, 20 parts of Cortex Magnoliae Officinalis, 30 parts of Rhizoma Zingiberiss, 40 parts of the Radix Paeoniae Albas, 30 parts in Radix Glycyrrhizae.
4, pharmaceutical formulation side of the present invention separates:
The present invention fills a prescription and adopts Radix Puerariae, windproof, the Radix Angelicae Dahuricae, Herba Pogostemonis to discongest pathogenic factor in the exterior, and dispelling cold and removing dampness, is stranded exterior syndromes such as weight, fever with chills all over the body at the dizzy heavy pain of treatment; Damp and hot with Rhizoma Atractylodis, Radix Scutellariae Qinghua; Rhizoma Zingiberis, the Rhizoma Pinelliae, Pericarpium Citri Reticulatae, Fructus Amomi, Fructus Amomi Rotundus warming middle-JIAO and strengthening the spleen stomach function regulating, fragrant removing dampness is turbid, treatment nausea and vomiting, distension; With the relieving distension of regulating the flow of vital energy of Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, the Radix Linderae, sending down the abnormal ascending QI closes the Poria dampness removing, with the Radix Paeoniae Alba, Radix Glycyrrhizae relieving spasm to stop pain, sour and sweet drugs can transforme into YIN.We contain GEGEN QINLIAN TANG, huoxiang zhengqi powder, leaves of pulse plants Piao Xia Siberian cocklebur soup, sand half lizhong decoction, peony and licorice decoction, and full side collection five side's quintessences add and simplify sanction, are treatment acute gastroenteritis compound recipes evident in efficacy.
The present invention's prescription is to sum up through clinical prolonged application to form, and according to the available data retrieval, finds as yet and the similar pure Chinese medicinal preparation of the present invention, is the practical medicament of clinical emergency with travelling indispensability at home commonly used.
5, the main effect of prescription drug of the present invention:
Radix Puerariae: these article are sweet, hot, cool, go into the taste warp, dispelling exopathogens from superficies of the body, and expelling pathogenic factors from muscles for reducing heat, for controlling the principal agent of the lossless headache stiffness of the nape of exterior heat, kind sending up the lucid YANG is inspired gas rising and promoting the production of body fluid to quench thirst, the antidiarrheal dysentery relieving of the clear sun of taste.Windproof: the hot sweet tepor of these article, go into liver, spleen channel, the benefaction whole body is main to dispel the wind, wind and cold wind heat exterior syndrome all can be used, again can removing dampness to relieve pain, expelling wind and relieving convulsion regulating the liver and spleen.The Radix Angelicae Dahuricae: the hot temperature aroma of these article is strong, the diffusing cold relieving of row, and the dry dehumidifying of property, fragrance is walked to scurry and is reached, the both kind Yangming Channel wind and cold that looses, damp, kind again clearing the nasal passage pain relieving is for controlling neck pain, nasal sinusitis, toothache key medicine.Herba Pogostemonis: hot the loosing of these article fragrance and not dry strong, the taste lung meridian is gone in tepor removing dampness and not scorching, and the kind removing dampness of merit is amusing; With middle preventing or arresting vomiting, expelling summer-heat is delivered, all middle burnt wet resistance feeling of fullness vomiting and nausea, and anorexia is not hungry; The summer Sunstroke wets, the cold and heat headache that the sense cold fluid-retention is cold, and chest and diaphragm is full vexed, stomachache vomiting and diarrhoea etc.Rhizoma Atractylodis: this moral character warm-dryness syndrome looses, and goes into the taste warp, but turbid strongly fragrant of interior removing dampness, the external enwergy heresy of rheumatism of loosing, thus the merit that drying damp and strengthening spleen, wind-damp dispelling is arranged and deliver, no matter all damps are about the disease the exterior and the interior, all can use.Radix Scutellariae: these article bitter cold, heat clearing and damp drying, damp-heat in upper-JIAO and lung-fire during You Shanqing lets out, for control hygropyrexia, heat-damp in summer, breast gastral cavity painful abdominal mass is vexed and cough due to lung-heat's key medicine.The Rhizoma Pinelliae: the hot temperature of these article and dry, it is wet and reduce phlegm turbidly to be longer than dry spleen, and gastric qi falls in warming the lung and change cold-phlegm and preventing or arresting vomiting is told, for controlling the key medicine of damp-phlegm, cold-phlegm and vomiting.Pericarpium Citri Reticulatae: the arduous temperature of these article, its gas fragrance, hot row hardship is fallen, and can nurse one's health spleen lung qi machine, and merit is apt to regulating qi-flowing for strengthening spleen, and drying dampness to eliminate phlegm is the good merchantable brand of activating QI to eliminate phlegm, relieving distension, preventing or arresting vomiting.Poria: sweet the providing additional supplies of these article oozed, and acts on gentlely, and no cold and heat are partially, and diuretic and just not hindering is the promoting diuresis to eliminate damp pathogen key medicine.Fructus Amomi: the hot fragrant temperature of these article is diffusing, burnt turbid damp in the aromatization, and the gas that stagnates of temperature reason taste has good removing dampness appetizing, and is warming spleen and stopping diarrha, and the antiabortive effect of regulating the flow of vital energy is apt to control the wet wrist distention and fullness in the abdomen that is stranded spleen soil and stagnation of QI in spleen and stomach, anorexia, the kind again vomiting and diarrhoea of controlling Deficiency and coldness of spleen and stomach.Fructus Amomi Rotundus: the hot fragrant warm-dryness syndrome of these article, merit is apt to the dampness circulation of qi promoting, and warming middle-JIAO to arrest vomiting both had been suitable for stagnation of cold-damp in middle-JIAO, the coldness and pain in the epigastrium due to the stagnation of QI in spleen and stomach, nausea and vomiting can be controlled the insufficiency of the spleen wet chronic diarrhea of cold folder that has again.Fructus Aurantii Immaturus: these article toil is slightly cold, and it is strong that row stagnate to remove the power of letting out, and is longer than broken the gas that stagnates, and removing food stagnancy stagnates, and removes feeling of fullness, is taste edema caused by disorder of QI medicine, stops in all QI-mass are stagnant, and mechanism of qi is obstructed and heavily waits disease after seeing breast abdomen feeling of fullness distending pain, constipation or dysentery, no matter but QI and blood phlegm-damp fit applications all.The Radix Linderae: the hot row temperature of these article is logical, on walk the gas that the spleen lung is unclogged and readjusted the breast abdomen, assign kidney and bladder, can remove bladder cold air by warming kidney for dispelling cold, chest and abdomen swelling and pain, hernia, the dysmenorrhes of all cold strongly fragrant stagnation of QIs, the frequent urination and enuresis of deficiency-cold in the urinary bladder is medicine commonly used.Mangnolia officinalis: the bitter ability of these article therapeutic method to keep the adverse QI flowing downwards, hot ability eliminating stagnation, but temperature dampness can descend tangible reality full; Can remove invisible wet fullly again, merit is apt to dampness, circulation of qi promoting, removing food stagnancy, relievings asthma all food stagnations; Wet stopping, expectorant is stopped up, all cards due to the stagnation of QI, retention of dampness in middle-JIAO; Gastral cavity painful abdominal mass due to the stagnation of QI in spleen and stomach is indigestion and loss of appetite, the constipation that the intestines and stomach is stagnant, and the cough with asthma QI rising in reverse order of lung-QI being unable to descend all can come into operation.Rhizoma Zingiberis: the hot and cold-evil of the taste of dispelling of these article, can help the yang-energy of taste again, be the warming spleen and stomach for dispelling cold key medicine, no matter be the excess-cold of invading in the exogenous cold, or the deficiency and coldness of taste YANG QI deficiency all can use, and hot kind logical heart-yang and recuperating depleted YANG is promoted blood circulation.The Radix Paeoniae Alba: sweet being slightly cold of these article acid, go into the liver spleen channel, merit is apt to nourishing blood to suppress the hyperactive liver, invigorating YIN to suppress YANG, the gastral cavity abdomen spasm of the limbs of treating the liver spleen imbalance is had a pain, dysentery stomachache.Radix Glycyrrhizae: these article are given birth to sweet flat, process and use sweet temperature, have effects such as spleen reinforcing, lung moistening, detoxifcation, emergency, coordinating the actions of various ingredients in a prescription, are used for the heart, lung, taste deficiency of QI in middle-JIAO, control sore and toxic, and food, drug intoxication are separated hundred poison of drug, alleviate spasm of the limbs, diseases such as stomachache contracture.
Four, method for preparing:
1,, claims sufficient deal splendid attire respectively, drying for standby by the optimum weight proportioning with each drug purification of the present invention.
2, Radix Scutellariae, the Radix Paeoniae Alba are pressed process of preparing standard wine and fry subsequent usely, it is subsequent use to chapping that Fructus Aurantii Immaturus is fried bubble.
3, whole medicines are closed the even broken coarser powder that is, add 8 times of amounts of drinking water and soak 24h, whenever stir once at a distance from 8h.
4, will soak medicamental pulverata and water heated and boiled 1.5h behind the 24h, leaching liquid is crossed in cooling; Medicinal residues are added 6 times of amounts of water heated and boiled 2h, cross leaching liquid, twice gained medicinal liquid closed the even 1h that boils, cross the clarification of leaching liquid.
5, will clarify the method for preparing that medicinal liquid is pressed oral liquid, be prepared as oral liquid, the vial packing, every bottle of 15ml, the sealing sterilization, per 5 is a box, it is box-packed to be equipped with suction pipe.
6, method for preparing the 1st, 2 purifications, the process of preparing Chinese medicine, drying for standby medicines are closed even, adopt superfine communication technique, pulverize and be fine powder.
7, the micropowders packing there is not toxic capsule, every 0.5g, per 100 bottled sterilization sealings.
8, micropowders is added amylum adhesive, be pressed into tablet, the heavy 0.5g of sheet, per 100 bottled sterilization sealings.
9, the oral liquid of medication preparation of the present invention, capsule, tablet are said dosage forms on any pharmaceutics.
Claims (9)
1. the invention discloses a kind of medicine of treating acute gastroenteritis and preparation method thereof, it is made up of following medicine and weight proportion thereof: Radix Puerariae 20-50 part, windproof 15-50 part, Radix Angelicae Dahuricae 15-40 part, Herba Pogostemonis 15-50 part, Rhizoma Atractylodis 20-60 part, Radix Scutellariae 20-50 part, Rhizoma Pinelliae 20-50 part, Pericarpium Citri Reticulatae 10-40 part, Poria 20-60 part, Fructus Amomi 10-40 part, Fructus Amomi Rotundus 10-30 part, Fructus Aurantii Immaturus 10-30 part, Radix Linderae 10-40 part, Cortex Magnoliae Officinalis 10-40 part, Rhizoma Zingiberis 10-40 part, Radix Paeoniae Alba 15-50 part, Radix Glycyrrhizae 10-30 part.
2. the preferred weight proportioning of medicine of the present invention is:
Radix Puerariae 15-50 part, windproof 15-50 part, Radix Angelicae Dahuricae 10-40 part, Herba Pogostemonis 15-50 part, Rhizoma Atractylodis 15-60 part, Radix Scutellariae 15-50 part, Rhizoma Pinelliae 15-50 part, Pericarpium Citri Reticulatae 10-30 part, Poria 20-50 part, Fructus Amomi 10-30 part, Fructus Amomi Rotundus 10-30 part, Fructus Aurantii Immaturus 10-30 part, Radix Linderae 10-30 part, Cortex Magnoliae Officinalis 10-30 part, Rhizoma Zingiberis 10-40 part, Radix Paeoniae Alba 15-40 part, Radix Glycyrrhizae 10-30 part.
3. the optimum weight proportioning of medicine of the present invention is:
40 parts of Radix Puerariaes, windproof 30 parts, 30 parts of the Radixs Angelicae Dahuricae, 40 parts of Herba Pogostemoniss, 50 parts of Rhizoma Atractylodis, 40 parts of Radix Scutellariaes, 50 parts of the Rhizoma Pinelliaes, 30 parts of Pericarpium Citri Reticulataes, 50 parts in Poria, 30 parts of Fructus Amomis, 20 parts of Fructus Amomi Rotunduss, 15 parts of Fructus Aurantii Immaturuss, 20 parts of the Radixs Linderae, 20 parts of Cortex Magnoliae Officinalis, 30 parts of Rhizoma Zingiberiss, 40 parts of the Radix Paeoniae Albas, 30 parts in Radix Glycyrrhizae.
4. with each drug purification of the present invention, claim sufficient deal splendid attire respectively, drying for standby by the optimum weight proportioning; Radix Scutellariae, the Radix Paeoniae Alba are pressed process of preparing standard wine fry subsequent usely, it is subsequent use to chapping that Fructus Aurantii Immaturus is fried bubble.
5. whole medicines are closed and spare the broken coarser powder that is, add 8 times of drinking waters and measure immersion 24h, every separated 8h stirs once, and medicamental pulverata and water heated and boiled 1.5h with behind the immersion 24h lower the temperature, and cross leaching liquid; Medicinal residues are added 6 times of amounts of water heated and boiled 2h, cross leaching liquid; Twice gained medicinal liquid closed the even 1h that boils, cross the clarification of leaching liquid.
6. will clarify the method for preparing that medicinal liquid is pressed oral liquid, be prepared as oral liquid, the vial packing, every bottle of 15ml, the sealing sterilization, per 5 is a box, it is box-packed to be equipped with suction pipe.
7. method for preparing the 1st, 2 purifications, the process of preparing Chinese medicine, drying for standby medicines are closed evenly, adopt superfine communication technique, pulverize and be fine powder the micropowders packing not to be had toxic capsule, every 0.5g, per 100 bottled sterilizations sealings.
8. micropowders is added amylum adhesive, be pressed into tablet, the heavy 0.5g of sheet, per 100 bottled sterilization sealings.
9. the oral liquid of medication preparation of the present invention, capsule, tablet are said dosage forms on any pharmaceutics, the prescription protection.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012102790034A CN102755623A (en) | 2012-07-27 | 2012-07-27 | Medicine for treating acute gastroenteritis and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104083695A (en) * | 2014-07-02 | 2014-10-08 | 卞佳林 | Traditional Chinese medicinal preparation for treating acute enteritis, and preparation method and application thereof |
| CN104645274A (en) * | 2013-11-21 | 2015-05-27 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicine composition for treating cow acute gastroenteritis and preparation method thereof |
| CN105288422A (en) * | 2015-11-09 | 2016-02-03 | 张健 | Traditional Chinese medicine preparation used for treating eilema syndromes and preparation method |
-
2012
- 2012-07-27 CN CN2012102790034A patent/CN102755623A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104645274A (en) * | 2013-11-21 | 2015-05-27 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicine composition for treating cow acute gastroenteritis and preparation method thereof |
| CN104083695A (en) * | 2014-07-02 | 2014-10-08 | 卞佳林 | Traditional Chinese medicinal preparation for treating acute enteritis, and preparation method and application thereof |
| CN105288422A (en) * | 2015-11-09 | 2016-02-03 | 张健 | Traditional Chinese medicine preparation used for treating eilema syndromes and preparation method |
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Application publication date: 20121031 |