CN102755500B - Basil ointment for treating scalding and preparation method thereof - Google Patents
Basil ointment for treating scalding and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a basil ointment for treating scalding and a preparation method thereof. The basil ointment is prepared by radix ampelopsis, long-leave garden burnet, lysimachia hemsleyana, leaf of shrubby baeckea, basil essential oil, grape seed oil and castor oil by weight. The basil ointment has effects of restraining, diminishing inflammation, removing corrosion, generating muscle andpulling heat-toxicity, is used for treating the scalding, and is rapid in effect, good in curative effect and high in cure rate.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of scald and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Scald is Body contact high temperature oil, gas, water or other objects and cause the damage of skin histology.The degree of scalding is divided into three degree.I-II is scalded and is skin surface or corium damage, and local congestion and swelling pain is obvious.It is subcutaneous that the III degree is scalded, and fat, muscle, skeleton have damage, and serious sensitive part is scalded, and particularly women's head-ornaments, cervical region all can cause shock at any time.At present, doctor trained in Western medicine is taken antibiotics treatment mostly, and preventing wound infection, but unsatisfactory curative effect is particularly taken antibiotics for a long time to the severe infections person, easily causes a lot of untoward reaction, and more side effect is arranged.Therefore, there is great demand in people to the Chinese medicine medicine of effective treatment scald.
Summary of the invention
The inventor is according to the research of theory of Chinese medical science and clinical repeatedly test and checking, the Chinese medicine medicine that has found effective treatment to scald finally, thus finished the present invention.
Purpose of the present invention just provides a kind of Chinese medicine composition medicine that can effectively treat scald.
Another object of the present invention has just provided the preparation method of this composition of medicine.
Medicine of the present invention is selected Radix Ampelopsis for use, the Radix Sanguisorbae that comes into leaves (Radix Sanguisorbae), select gland Lysimachia christinae Hance (Herba Lysimachiae), Folium Baeckeae, kincup, Herba Hyperici perforati, Aloe ferox Miller, Radix angelicae dahuricae, ajuga decumbens and Herba Ocimi (Herba Ocimi Pilosi) quintessence oil, Oleum Vitis viniferae, Oleum Ricini and make up, make each efficacy of drugs produce synergism these drug regimens, thereby can treat scald fast.Wherein select for use Radix Ampelopsis to be because its nature and flavor hardship, sweet, hot, cool in nature has heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, granulation promoting, the function of pain relieving.Be used for carbuncle sore tumefacting virus, carbuncle on the back is treated skin ulcer, and scrofula is scalded, and sprains dysentery, hemorrhoidal hamorrhage.Selecting the Radix Sanguisorbae that comes into leaves for use is that cold nature has cooling blood for hemostasis, heat-clearing and toxic substances removing, the function of promoting tissue regeneration and ulcer healing because of its nature and flavor hardship, acid.Be used for having blood in stool bleeding hemorrhoids, dysentery, hematuria, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus.Select for use a gland Lysimachia christinae Hance to be because its nature and flavor are light, cold nature has heat clearing away, function of gallbladder promoting, diuresis and expelling stone, detoxifcation, the function of promoting blood circulation to remove blood stasis.Be used for cholelithiasis, the sacculation inflammation, icterohepatitis, urinary system calculus, edema, venom, poisonous fungus and drug intoxication, suppurative inflammation is controlled in external, burn and scald.Selecting Folium Baeckeae for use is because of its nature and flavor suffering, hardship, cold in nature, and eliminating damp-heat is arranged, the function of killing parasites for relieving itching, and root has expelling wind and removing dampness, and function is looked in the detoxifcation diuresis.Twig, leaf are used for acute gastroenteritis, bacillary dysentery, and hepatitis is used for trichomonal vaginitis, skin eczema, venom, burn outward; Root is used for cold, fever, icterohepatitis, stomachache, enteritis, rheumatic arthralgia, beriberi, cystitis, dysuria.Selecting kincup for use is because of its nature and flavor suffering, little hardship, cool in nature, clearing away heat-damp and promoting diuresis is arranged, the function of detoxifcation.Be used for heatstroke, urinary tract infection; Outer burn and scald, the venom of being used for.Selecting Herba Hyperici perforati for use is because its nature and flavor bitterness, and property is flat, and heat-clearing and toxic substances removing is arranged, astringing to arrest bleeding, the function of dampness removing is used for rheumatic ostalgia, mouth and nose are given birth to skin ulcer, toxic swelling, spitting of blood is spitted blood, discharging fresh blood stool, scald hemorrhage, dizziness and red eyes, urinary tract infection, menoxenia.Select for use Aloe ferox Miller to be because its nature and flavor hardship is cold in nature, removing heat from the liver is arranged, the function of relieving constipation is used for the dizziness of Liver Channel excess-heat, headache, and tinnitus, agitation, constipation, pediatric epilepsy scared, dental caries is controlled in external, furuncle carbuncle poison, burn and scald, exudative dermatitis.Select for use Radix angelicae dahuricae to be because its nature and flavor suffering is warm in nature, dispel the wind cold relieving, dampness, understand things pain-stopping, the function of detumescence and apocenosis.Be used for the anemofrigid cold headache, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.Select for use ajuga decumbens to be because its nature and flavor hardship is cold in nature, heat-clearing and toxic substances removing is arranged, reducing swelling and alleviating pain, the function of removing heat from blood suppressing the hyperactive liver.Be used for upper respiratory tract infection, tonsillitis, pharyngitis, bronchitis, pneumonia, lung abscess, gastroenteritis, hepatitis, appendicitis, mastitis, acute conjunctivitis, hypertension.Traumatic injury is controlled in external, traumatic hemorrhage, carbuncle furuncle infections, burn and scald, venom.Select for use the Herba Ocimi (Herba Ocimi Pilosi) quintessence oil to be because its main component is ocimene (Ocimene), australene (α-Pinene), 1,8-cineole (1,8-Cineole, Eucalyptole), labor Camphor tree alcohol (Linalool), Mang geraniol (Geraniol), limonene (Limonene), carene-3 (⊿ 3-Carene), estragole (Methylchavicol), eugenol (Eugenol), methyleugenol (Eugenol methyl ether), methoxybenzene (Anethole), methyl cinnamate (Methyl cinnaminate), hexene-3-ol-1(3-Hexen-1-ol), octanone-3(3-Octanone) and furfural (Furfural) etc., contain volatile oil 0.02-0.04%, the extraction of Herba Ocimi (Herba Ocimi Pilosi) quintessence oil is from blade and fresh idea, be colourless quintessence oil, abnormal smells from the patient is refrigerant, nervous system there is very strong stimulation, use when tired and inspire enthusiasm immediately, focus one's attention on, mouthfeel is fresh and sweet, slightly hot flavor.The Herba Ocimi (Herba Ocimi Pilosi) quintessence oil also has the improvement of tightening up and blocks skin, the control acne, control head and migraine, flu, unusual, the myalgia of digestion, can stimulate the estrogen secretion, be used for opsomenorrhea, prolonged not following, also can be used for cough, rheumatism, puerpera's postpartum lactescence quantity not sufficient, carsickness is seasick etc., it can treat various respiratory tract infection, also can alleviate stomach spasm or reduce dysmenorrhea.Dryness hydropenia or aging skin coarse, wrinkle there are the effect of moistening, also can be used for frequent overtime work and long-term black eye, eye pouch in the face of the computer appearance.The Herba Ocimi (Herba Ocimi Pilosi) quintessence oil has stronger medical value, its nature and flavor suffering, temperature, has relieving the exterior syndrome by diaphoresis, expelling wind and removing dampness, the function of eliminating stasis to stop pain, be used for anemofrigid cold, headache, pipe abdomen fullness, dyspepsia, stomachache, enteritis, diarrhea, treating swelling and pain by traumatic injury, rheumatic arthritis, external curing venom, eczema, dermatitis.Select for use Oleum Vitis viniferae to be because Oleum Vitis viniferae contains linoleic acid and proanthocyanidin.Linoleic acid can be resisted free radical, and aging resistance helps to absorb vitamin C and E, strengthens the elasticity of blood circulation, reduces ultraviolet injury, and the collagen protein in the protection skin improves venous engorgement and edema, the prevention melanin deposition.Proanthocyanidin has the protection blood vessel elasticity, and the protection skin avoids ultraviolet afflicting with great suffering torment, and the destruction of prevention collagen fiber and elastic fiber makes skin keep due elasticity and tension force, avoids skin sagging and wrinkle to produce.Penetration is strong, and salubrious non-greasy is very easily by skin absorbs.Select for use Oleum Ricini to be because the sweet suffering of its nature and flavor is flat, poisonous.Go into large intestine, lung meridian.Detumescence and drawing out poison is arranged, rush down the logical function that stagnates down.Control constipation due to dry stool, skin ulcer scabies, burn.
The drug dose of the present invention's combination also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has better curative effect in following weight range:
Radix Ampelopsis 3-10 restrains Radix Sanguisorbae 8-15 gram point gland Lysimachia christinae Hance 4-6 grams that come into leaves
Folium Baeckeae 3-7 gram kincups 5-8 gram Herba Hyperici perforatis 3-5 grams
Aloe ferox Miller 3-5 gram Radix angelicae dahuricae 5-10 gram ajuga decumbenses 4-8 grams
Herba Ocimi (Herba Ocimi Pilosi) quintessence oil 5-10 gram Oleum Vitis viniferaes 20-30 gram Oleum Ricini 20-30 grams
Preferable amount is:
Radix Ampelopsis 5 restrains Radix Sanguisorbae 10 gram point gland Lysimachia christinae Hance 5 grams that come into leaves
Folium Baeckeae 6 gram kincups 7 gram Herba Hyperici perforatis 4 grams
Aloe ferox Miller 4 gram Radix angelicae dahuricae 8 gram ajuga decumbenses 6 grams
Herba Ocimi (Herba Ocimi Pilosi) quintessence oil 8 gram Oleum Vitis viniferaes 25 gram Oleum Ricini 25 grams
The preparation method of medicine of the present invention is as follows
One, gets the raw materials ready
1, Radix Ampelopsis: remove stem and thin fibrous root, clean, section is dried;
2, the Radix Sanguisorbae that comes into leaves: choose decontamination, except the dedust bits;
3, some gland Lysimachia christinae Hance: choose decontamination, except the dedust bits;
4, Folium Baeckeae: remove impurity and ash bits;
5, kincup: choose decontamination, except dedust bits, drying;
6, Herba Hyperici perforati: choose decontamination, except the dedust bits;
7, Aloe ferox Miller: wash, dry;
8, Radix angelicae dahuricae: choose decontamination, wash, soak, pull out and run through, slightly shine when not having soapy feeling to crust, again behind the moistening, chip drying;
9, ajuga decumbens: choose decontamination, wash, dry;
10, Herba Ocimi (Herba Ocimi Pilosi) quintessence oil: get Herba Ocimi (Herba Ocimi Pilosi) stem leaves of plants, flower core herb, remove root, mud, rotted leaf, impurity, dry, extract quintessence oil;
11, Oleum Vitis viniferae: the Semen Vitis viniferae that will remove epidermis sarcocarp is chosen only and is dried, oil expression;
12, Oleum Ricini: break kind of a subshell into pieces, choose and get kernel, oil expression.
Two, preparation
1, with the Radix Ampelopsis of described weight, the Radix Sanguisorbae that comes into leaves, some gland Lysimachia christinae Hance, kincup, Herba Hyperici perforati, Radix angelicae dahuricae grind into powder;
2, Aloe ferox Miller, Folium Baeckeae, ajuga decumbens are decocted with water, for the first time add 4 times of amounts of water, soaks after 60 minutes, intense fire decocts boiling 10 minutes, the reuse slow fire boiling time decoction liquor of namely winning in 20 minutes, will the first time decoction liquor pour in the container; Medicinal residues after filtering are for the first time added 2 times of amounts of water, boil with high heat earlier, reuse slow fire boiling 20 minutes, decoction liquor is poured in the container for the second time.Twice decoction liquor carried out mixing and stirring, and reuse slow fire boiling 20 minutes gets mixed liquor;
3, Herba Ocimi (Herba Ocimi Pilosi) quintessence oil: get Herba Ocimi (Herba Ocimi Pilosi) plant stem-leaf, pistil herb, remove root mud rotted leaf and impurity.Steep 2-3h with the Alumen water logging in the Herba Ocimi (Herba Ocimi Pilosi) input sedimentation tank with drying, the weight ratio of water and Alumen is 1:0.0002; With putting into boiler after the clean water cleaning, the addition of raw material is 80-90% of boiler volume, and amount of water was as the criterion to soak raw material, and Herba Ocimi (Herba Ocimi Pilosi) plant fresh and drying will be distinguished steaming and decocting; To heating at the bottom of the boiler, carry out vapor distillation, the stirring impeller of opening simultaneously in the boiler overturns to raw material stirring, along with increasing of temperature, Herba Ocimi (Herba Ocimi Pilosi) quintessence oil in the plant material enters in the condenser along with steam produces the gas that mixes with water respectively through pot top gooseneck conduit, convert oil-water mixture to through condenser condenses and be disposed in the oil water separator, distillation time is 60-80 minutes; Collect the upper strata oil reservoir that oil water separator is separated, contain a spot of quintessence oil in the water of lower floor, be collected in the container back warp and cross repetition distillation extraction recovery quintessence oil wherein, pass through purification filtering again, namely obtain pure natural Herba Ocimi (Herba Ocimi Pilosi) quintessence oil;
4, Semen Vitis viniferae, castor bean are put into squeezer respectively, get its oil, get Oleum Vitis viniferae, Oleum Ricini respectively;
5, the powder that said medicine is ground, the mixed liquor of extraction, the Herba Ocimi (Herba Ocimi Pilosi) quintessence oil of distillation and the Oleum Vitis viniferae of squeezing and Oleum Ricini mixing and stirring are made ointment, namely get Herba Ocimi (Herba Ocimi Pilosi) ointment of the present invention.
The effect that medicine of the present invention has convergence, antiinflammatory, removing the necrotic tissue and promoting granulation, pulls out pyretic toxicity is used for the treatment of scald, can make the injury rapidly, heat radiation up hill and dale, skin heart is shunk, reduce and ooze out and edema, alleviating pain reduces blister and forms, and prevents that wound surface from forming cicatrix.Prevent wound infection, can impel the affected part to form dry crusts rapidly, scald the affected part and heal rapidly.
The specific embodiment
Below further sets forth the beneficial effect of medicine of the present invention by testing example, these are tested the routine animal toxicity test of medicine of the present invention that comprised and report and clinical observation material.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get 30 of rabbit, male and female dual-purpose, body weight 2.0-2.4kg, be pressed in the rabbit abdominal part of dialling the clean rabbit hair and made film in 20 minutes with being immersed in cotton swab in the acetic acid, make the diameter 5mm of mucosa ulcer, divide two groups with rabbit after making film, every group 15, wherein one group is the overdose test group, and another group is the normal amount test group; The super quantity group is every day 6 times, and normal amount is every day 3 times, and administering mode is the application administration, connects to apply 7 days, observes the administration reaction every day, and the result shows that two groups of rabbit activities, diet are normal, and medicine does not have bad toxic and side effects.
The clinical observation material that [test example 2] Drug therapy of the present invention is scalded:
1, physical data
Accept out-patient's totally 391 examples for medical treatment, wherein I-II degree is scalded patient's 228 examples, and the III degree is scalded patient's 163 examples.
2, diagnostic criteria
I-II degree is scalded: skin surface or corium damage, the affected part congestion and swelling pain is obvious.
The III degree is scalded: subcutaneous fat, muscle have damage, and the symptom of having a fever appears in patient, and the pain increased for affected part, fester, suppurate.
3, Therapeutic Method
Select above-mentioned ointment for use, be applied to the affected part to the patient.I-II degree is scalded patient's external application every day 2 times, and early, respectively smear 1 time evening, 7 days is a course for the treatment of, continuously 2 courses for the treatment of of external application.The III degree is scalded patient's external application every day 3 times, every day early, middle and late respectively smearing 1 time, 7 days is a course for the treatment of, continuously external application 4-5 course for the treatment of.During use, clean wound surface, ointment is spread on affected part, need not the sterilizing room operation.
4, efficacy assessment standard
Produce effects: treatment back clinical symptom disappearance, it is normal that body constitution is recovered, and observes and do not have the recidivist half a year;
Take a turn for the better: clinical symptoms is obviously improved, and body constitution is progressively recovered;
Invalid: clinical partial symptoms disappears or does not have change, does not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, scald patient's 391 examples with Drug therapy of the present invention, wherein I-II degree is scalded patient's 228 examples, produce effects 220 examples as a result, obvious effective rate is 96.49%, 8 examples that take a turn for the better, improvement rate is 3.5%, total effective rate is 100%.The III degree is scalded patient's 163 examples, produce effects 140 examples as a result, and obvious effective rate is 85.89%, 20 examples that take a turn for the better, improvement rate is 12.27%, total effective rate is 98.16%.
Claims (3)
1. Herba Ocimi (Herba Ocimi Pilosi) ointment for the treatment of scald, it is characterized in that: it is to be made by the crude drug in the following weight scope:
Radix Ampelopsis 3-10 restrains Radix Sanguisorbae 8-15 gram point gland Lysimachia christinae Hance 4-6 grams that come into leaves
Folium Baeckeae 3-7 gram kincups 5-8 gram Herba Hyperici perforatis 3-5 grams
Aloe ferox Miller 3-5 gram Radix angelicae dahuricae 5-10 gram Herba Ajugaes 4-8 grams
Herba Ocimi (Herba Ocimi Pilosi) quintessence oil 5-10 gram Oleum Vitis viniferaes 20-30 gram Oleum Ricini 20-30 grams.
2. according to the Herba Ocimi (Herba Ocimi Pilosi) ointment of the described treatment scald of claim 1, it is characterized in that: wherein the consumption of each crude drug is:
Radix Ampelopsis 5 restrains Radix Sanguisorbae 10 gram point gland Lysimachia christinae Hance 5 grams that come into leaves
Folium Baeckeae 6 gram kincups 7 gram Herba Hyperici perforatis 4 grams
Aloe ferox Miller 4 gram Radix angelicae dahuricae 8 gram Herba Ajugaes 6 grams
Herba Ocimi (Herba Ocimi Pilosi) quintessence oil 8 gram Oleum Vitis viniferaes 25 gram Oleum Ricini 25 grams.
3. according to the Herba Ocimi (Herba Ocimi Pilosi) ointment of claim 1 or 2 described treatments scalds, it is characterized in that: it comprises the following steps:
(1) gets the raw materials ready
(1) Radix Ampelopsis: remove stem and thin fibrous root, clean, section is dried;
(2) Radix Sanguisorbae that comes into leaves: choose decontamination, except the dedust bits;
(3) some gland Lysimachia christinae Hance: choose decontamination, except the dedust bits;
(4) Folium Baeckeae: remove impurity and ash bits;
(5) kincup: choose decontamination, except dedust bits, drying;
(6) Herba Hyperici perforati: choose decontamination, except the dedust bits;
(7) Aloe ferox Miller: wash, dry;
(8) Radix angelicae dahuricae: choose decontamination, wash, soak, pull out and run through, slightly shine when not having soapy feeling to crust, again behind the moistening, chip drying;
(9) Herba Ajugae: choose decontamination, wash, dry;
(10) Herba Ocimi (Herba Ocimi Pilosi) quintessence oil: get Herba Ocimi (Herba Ocimi Pilosi) stem leaves of plants, pistil herb, remove root, mud, rotted leaf, impurity, dry, extract quintessence oil;
(11) Oleum Vitis viniferae: the Semen Vitis viniferae that will remove epidermis sarcocarp is chosen only and is dried, oil expression;
(12) Oleum Ricini: break kind of a subshell into pieces, choose and get kernel, oil expression;
(2) preparation
(1) with the Radix Ampelopsis of described weight, the Radix Sanguisorbae that comes into leaves, some gland Lysimachia christinae Hance, kincup, Herba Hyperici perforati, Radix angelicae dahuricae grind into powder;
(2) Aloe ferox Miller, Folium Baeckeae, Herba Ajugae are decocted with water, for the first time add 4 times of amounts of water, soaks after 60 minutes, intense fire decocts boiling 10 minutes, the reuse slow fire boiling time decoction liquor of namely winning in 20 minutes, will the first time decoction liquor pour in the container; Medicinal residues after filtering are for the first time added 2 times of amounts of water, boil with high heat earlier, reuse slow fire boiling 20 minutes, decoction liquor is poured in the container for the second time, and twice decoction liquor carried out mixing and stirring, and reuse slow fire boiling 20 minutes gets mixed liquor;
(3) Herba Ocimi (Herba Ocimi Pilosi) quintessence oil: get Herba Ocimi (Herba Ocimi Pilosi) plant stem-leaf, pistil herb, remove root mud rotted leaf and impurity, steep 2-3h with the Alumen water logging in the Herba Ocimi (Herba Ocimi Pilosi) input sedimentation tank with drying, the weight ratio of water and Alumen is 1:0.0002; With putting into boiler after the clean water cleaning, the addition of raw material is 80-90% of boiler volume, and amount of water was as the criterion to soak raw material, and Herba Ocimi (Herba Ocimi Pilosi) plant fresh and drying will be distinguished steaming and decocting; To heating at the bottom of the boiler, carry out vapor distillation, the stirring impeller of opening simultaneously in the boiler overturns to raw material stirring, along with increasing of temperature, Herba Ocimi (Herba Ocimi Pilosi) quintessence oil in the plant material enters in the condenser along with steam produces the gas that mixes with water respectively through pot top gooseneck conduit, convert oil-water mixture to through condenser condenses and be disposed in the oil water separator, distillation time is 60-80 minutes; Collect the upper strata oil reservoir that oil water separator is separated, contain a spot of quintessence oil in the water of lower floor, be collected in the container back warp and cross repetition distillation extraction recovery quintessence oil wherein, pass through purification filtering again, namely obtain pure natural Herba Ocimi (Herba Ocimi Pilosi) quintessence oil;
(4) Semen Vitis viniferae, castor bean are put into squeezer respectively, get its oil, get Oleum Vitis viniferae, Oleum Ricini respectively;
(5) powder that said medicine is ground, the mixed liquor of extraction, the Herba Ocimi (Herba Ocimi Pilosi) quintessence oil of distillation and the Oleum Vitis viniferae of squeezing and Oleum Ricini mixing and stirring are made ointment, namely get Herba Ocimi (Herba Ocimi Pilosi) ointment of the present invention.
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| CN 201210279478 CN102755500B (en) | 2012-08-08 | 2012-08-08 | Basil ointment for treating scalding and preparation method thereof |
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| CN 201210279478 CN102755500B (en) | 2012-08-08 | 2012-08-08 | Basil ointment for treating scalding and preparation method thereof |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1689623A (en) * | 2004-04-24 | 2005-11-02 | 冯春 | Externally applied ointment for burns and scalds |
| CN102266441A (en) * | 2011-06-29 | 2011-12-07 | 李宏干 | Chinese medicinal ointment for treating burns and scalds |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1689623A (en) * | 2004-04-24 | 2005-11-02 | 冯春 | Externally applied ointment for burns and scalds |
| CN102266441A (en) * | 2011-06-29 | 2011-12-07 | 李宏干 | Chinese medicinal ointment for treating burns and scalds |
Non-Patent Citations (2)
| Title |
|---|
| 外用中药治疗烧烫伤的研究进展;袁汀;《光明中医》;20101130;第25卷(第11期);第2151-2153页 * |
| 袁汀.外用中药治疗烧烫伤的研究进展.《光明中医》.2010,第25卷(第11期),2151-2153页. |
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