CN102755190B - All-functional wide warm area low-temperature treatment equipment - Google Patents
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- CN102755190B CN102755190B CN201110104978.9A CN201110104978A CN102755190B CN 102755190 B CN102755190 B CN 102755190B CN 201110104978 A CN201110104978 A CN 201110104978A CN 102755190 B CN102755190 B CN 102755190B
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Abstract
The invention discloses all-functional wide warm area low-temperature treatment equipment, and relates to the technical field of medical equipment. The treatment equipment comprises a computer control system and a low-temperature processing system; the low-temperature processing system comprises a wide warm area refrigerating module, a low body temperature protecting module, a low temperature killing module and a thermal physiological parameter monitoring module; and the computer control system is used for receiving temperature information sent by the thermal physiological parameter monitoring module, generating a cold control command according to the temperature information and sending the cold control command to the low body temperature protecting module and the low temperature killing module. Function complementary refrigerating systems are integrated on the same treatment equipment, a proper refrigerating device and a proper refrigerating temperature can be selected according to the actual treatment condition, and all temperature areas required in clinical low-temperature treatment can be covered.
Description
Technical field
The present invention relates to technical field of medical equipment, particularly a kind of All-functional wide warm area low-temperature treatment equipment.
Background technology
Hypothermal medicine is the impact that research temperature reduces on human life's process, and the application branch of learning of cryogenic technique in the mankind struggle against with disease.It mainly comprises four large branches: body weight for humans wants the cryopreservation of cell tissue, organ, transplanting and clinical practice; Hypothermic anesthesia, brain hypothermia resuscitation; Hypothermia medical treatment; Cryosurgery tool is utilized to kill and wound abnormal structure as tumor etc.Except cryopreservation, other branches all belong to low temperature therapy category.Low temperature therapy is easy, easy and cheap, its first faced by problem be how to obtain the lower temperature matched with clinical object.As in hypothermic anesthesia, hypothermia medical treatment, brain hypothermia resuscitation and brain protection process, whole body or local temperature need be down to less than 37 DEG C and maintain certain hour.At present, according to body temperature, treatment temperature is fallen into 5 types in above-mentioned low temperature therapy: (1) profound low temperature: 0 ~ 5 DEG C; (2) ultra-deep low temperature: 5 ~ 10 DEG C; (3) profound hypothermia: 10 ~ 28 DEG C; (4) low temperature in: 28 ~ 32 DEG C; (5) mild hypothermia: 33 ~ 36 DEG C.And utilize cryosurgery tool to kill and wound abnormal structure, particularly during tumor tissues, for guaranteeing fragmentation effect, topical therapeutic temperature, generally lower than 0 DEG C, minimumly reaches-180 DEG C.
In modern science and technology, the method that can be used for freezing is a lot, as freezing by change of state, gas throttling refrigeration, semiconductor refrigerating, absorption refrigeration, immersion freezing type refrigeration, evaporation refrigeration, solid adsorption refrigeration and gas vortex effect refrigeration etc.Low temperature therapy and equipment thereof also have special requirement to refrigerating method, namely refrigeration system wants compact conformation, easy to use and reliable, efficiency is higher, have strict demand to cryogenic temperature and cold and control thereof, vibrate little, noise is low.Towards hypothermic anesthesia, hypothermia medical treatment, brain hypothermia resuscitation and brain protection time, temperature required a little less than body temperature, thus can adopt the methods such as the cold compress of multiple refrigeration principle or cryogenic liquid perfusion; And when utilizing cryosurgery to kill and wound abnormal structure, having of conventional refrigeration principle: (1) freezing by change of state; (2) gas throttling refrigeration; (3) semiconductor refrigerating.Develop dissimilar low temperature therapy apparatus based on these refrigerating methods, its Therapeutic Method is roughly divided into: (1) contact refrigeration; (2) insert freezing; (3) spray freezing, treatment system (Cryo-T) as cold in carbon dioxide, utilize the minimum treatment low temperature realizing-75 DEG C of the freezing by change of state effect of liquid carbon dioxide, range of application relates to beauty treatment, fracture, burn, rheumatism and postoperative rehabilitation etc.; The AK-1 cryosurgical treatment instrument that Cryoflex company produces, adopts nitrous oxide (N
2o) working medium throttling under 3.4 ~ 4.6MPa pressure can realize minimum probe temperature and is-89 DEG C, and therapeutic instrument can install various contact-type or ejection-type cryoprobe, directly liquid nitrous oxide can be injected into tissue and kill and wound; The SeedNetTM cryosurgery system that Galil Medical company produces, utilizes argon throttling refrigeration minimum temperature to reach-110 DEG C, is widely used in the treatment of prostate and tumor of kidney; The Hamilton etc. of Synerdyne company develops a kind of cryoprobe thermoelectric cooling combined with heat pipe, overcomes the shortcoming that thermoelectric cooling probe volume is excessive in the past, and the minimum temperature of its cryoprobe head can arrive-60 DEG C.In addition, the refrigeration plant of other principles also can be applied in cryosurgery, as the cold and hot compound armarium of immersion freezing type---the cold and hot therapeutic equipment of tumor micro-wound of Physical Chemistry Technology Inst., Chinese Academy of Sciences's development, first deep-frozen and high-temperature hot are melted combination, the rapid temperature transition between-180 DEG C and 80 DEG C can be realized, kill lesion tissue to greatest extent.
In sum, be not difficult to find, above-mentioned cryogenic refrigeration equipment all only possesses a kind of refrigeration principle, and operation temperature area is subject to the restriction of refrigeration principle and working medium self character, only can provide the therapeutic purposes of simple function.Up to the present, there is no a kind of low-temperature therapeutic equipment of global function molded breadth warm area both at home and abroad, all warm areas required in clinical low temperature therapy can be covered.
Summary of the invention
(1) technical problem that will solve
The technical problem to be solved in the present invention is: how to provide a kind of All-functional wide warm area low-temperature treatment equipment that can cover required all warm areas in clinical low temperature therapy.
(2) technical scheme
For solving the problems of the technologies described above, the invention provides a kind of All-functional wide warm area low-temperature treatment equipment, it comprises: computer operating system 100 and cryogenic process system 200; Described cryogenic process system 200 comprises: wide warm area refrigeration module 201, hypothermia protection module 202, low temperature kill and wound module 203 and hot physiological parameter monitoring module 204;
Described computer operating system 100, for receiving the temperature information that described hot physiological parameter monitoring module 204 sends, generates cold control command according to described temperature information, and is sent to described hypothermia protection module 202 and low temperature kills and wounds module 203;
Described wide warm area refrigeration module 201, connects described hypothermia protection module 202 and low temperature kills and wounds module 203, for generation of the cold needed for low temperature therapy;
Described hypothermia protection module 202, connects described computer operating system 100, for controlling the amount of the cold that described wide warm area refrigeration module 201 produces according to described cold control command, and exports described cold and carries out hypothermia protection;
Described low temperature kills and wounds module 203, connects described computer operating system 100, for controlling the amount of the cold that described wide warm area refrigeration module 201 produces according to described cold control command, and exports described cold and carries out low temperature and kill and wound;
Described hot physiological parameter monitoring module 204, for carrying out corresponding monitoring temperature, and is sent to described computer operating system 100 by the temperature information monitored.
Preferably, described cryogenic process system 200 also comprises power module 205;
Described power module 205 is for powering for other each modules of described cryogenic process system 200 and described computer operating system 100.
Preferably, described hypothermia protection module 202 comprises: the first cold input control device 2021 and the first cold output device 2022 be connected to each other;
Described first cold input control device 2021, in hypothermia protection process, controls the amount of the cold that described wide warm area refrigeration module 201 produces according to described cold control command;
Described first cold output device 2022, for exporting the cold that described wide warm area refrigeration module 201 produces in hypothermia protection process.
Preferably, described first cold output device 2022 comprises at least two kinds in body surface covering refrigerating plant, insertion type cryogen device for casting and cryogenic gas injection apparatus.
Preferably, described low temperature kills and wounds module 203 and comprises: the second cold input control device 2031 and the second cold output device 2032 be connected to each other;
Described second cold input control device 2031, in low temperature kill process, controls the cold of described wide warm area refrigeration module 201 generation according to described cold control command;
Described second cold output device 2032, for exporting the cold that described wide warm area refrigeration module 201 produces in low temperature kill process.
Preferably, described second cold output device 2032 comprises contact refrigeration device, insertion refrigerating plant, at least two kinds of spraying in refrigerating plant and insertion type refrigerating plant.
Preferably, described hot physiological parameter monitoring module 204 comprises, for carrying out the single point temperature measuring device 2041 of single point temperature measurement, and for carrying out the surface temperature measurement device 2042 of surface temperature measurement, measurement data is all sent to described computer operating system 100 by described single point temperature measuring device 2041 and described surface temperature measurement device 2042.
Preferably, described therapeutic equipment also comprises operating-table, and described cryogenic process system 200 is arranged on described operating-table.
Preferably, described wide warm area refrigeration module 201 comprises at least three kinds in phase-change refrigerating plant, gas throttling refrigerating plant, semiconductor cooling device, immersion freezing type refrigerating plant, absorption type refrigerating unit, solid adsorption refrigerating plant, evaporation refrigeration device and gas swirl refrigerating device.
Preferably, the refrigerant that described wide warm area refrigeration module 201 adopts is carbon dioxide, liquid nitrogen, Freon series cold-producing medium, nitrous oxide, argon, mist, hypothermic saline or thermoelectric material.
(3) beneficial effect
All-functional wide warm area low-temperature treatment equipment of the present invention, be integrated with the refrigeration system had complementary functions on the same device, suitable refrigerating plant and cryogenic temperature can be selected according to actual therapeutic situation, required all warm areas (temperature range for low temperature therapy :-180 DEG C ~ 36 DEG C) in clinical low temperature therapy can be covered.Secondly, this therapeutic equipment can implement hypothermia protection and low temperature killing ability simultaneously, thus is applied to efficiently as in the diseases that clinical difficulty is high, operation risk is large such as tumor near neurosurgery intracranial Posterior circle giant aneurysm, basis cranii brain stem.
Accompanying drawing explanation
Fig. 1 is the function structure chart of the All-functional wide warm area low-temperature treatment equipment described in the embodiment of the present invention;
Fig. 2 is the structure chart of the hypothermia protection module described in the embodiment of the present invention;
Fig. 3 is the structure chart that low temperature described in the embodiment of the present invention kills and wounds module;
Fig. 4 is the structure chart of the hot physiological parameter monitoring module described in the embodiment of the present invention.
Detailed description of the invention
Below in conjunction with drawings and Examples, the specific embodiment of the present invention is described in further detail.Following examples for illustration of the present invention, but are not used for limiting the scope of the invention.
Fig. 1 is the function structure chart of the All-functional wide warm area low-temperature treatment equipment described in the embodiment of the present invention.As shown in Figure 1, this equipment comprises computer operating system 100 and cryogenic process system 200.This cryogenic process system 200 comprises wide warm area refrigeration module 201, hypothermia protection module 202, low temperature kill and wound module 203, hot physiological parameter monitoring module 204 and power module 205.
Described computer operating system 100, for receiving the temperature information that described hot physiological parameter monitoring module 204 sends, and controls described hypothermia protection module 202 and low temperature according to this temperature information and kills and wounds module 203 and realize corresponding function.
Described wide warm area refrigeration module 201, connects described hypothermia protection module 202 and low temperature kills and wounds module 203, for generation of the cold needed for low temperature therapy.
Described hypothermia protection module 202, connects described computer operating system 100, and the cold produced for controlling and export described wide warm area refrigeration module 201 carries out hypothermia protection.
Described low temperature kills and wounds module 203, connects described computer operating system 100, and the cold produced for controlling and export described wide warm area refrigeration module 201 carries out low temperature and kills and wounds.
Described hot physiological parameter monitoring module 204, for carrying out corresponding monitoring temperature, and is sent to described computer operating system 100 by the temperature information monitored.
Described power module 205 is for powering for other each modules of described cryogenic process system 200 and described computer operating system 100.
This equipment also comprises operating-table, and each module of described cryogenic process system 200 is arranged on this operating-table.This operating-table is also provided with the mechanic adjustment unit can carrying out relative position adjustment according to targeted site position.Due to this operating-table and non-invention emphasis, do not repeat them here.
Fig. 2 is the structure chart of the hypothermia protection module 202 described in the embodiment of the present invention.As shown in Figure 2, described hypothermia protection module 202 comprises, the first cold input control device 2021 and the first cold output device 2022 be connected to each other.Described first cold input control device 2021, for controlling the cold that described wide warm area refrigeration module 201 produces in hypothermia protection process.Described first cold output device 2022; for exporting the cold that described wide warm area refrigeration module 201 produces in hypothermia protection process, it comprises at least two kinds in body surface covering refrigerating plant, insertion type cryogen device for casting and cryogenic gas injection apparatus.Often kind of cold output device all can be arranged in pairs or groups with any one refrigerating plant mutually.
Fig. 3 is the structure chart that low temperature described in the embodiment of the present invention kills and wounds module 203.As shown in Figure 3, described low temperature kills and wounds module 203 and comprises, the second cold input control device 2031 and the second cold output device 2032 be connected to each other.Described second cold input control device 2031, for controlling the cold that described wide warm area refrigeration module 201 produces in low temperature kill process.Described second cold output device 2032, for exporting the cold that described wide warm area refrigeration module 201 produces in low temperature kill process, it comprises contact refrigeration device, insertion refrigerating plant, at least two kinds of spraying in refrigerating plant and insertion type refrigerating plant.
Fig. 4 is the structure chart of the hot physiological parameter monitoring module 204 described in the embodiment of the present invention.As shown in Figure 4, described hot physiological parameter monitoring module 204 comprises, for carrying out the single point temperature measuring device 2041 of single point temperature measurement, and for carrying out the surface temperature measurement device 2042 of surface temperature measurement.Described single point temperature measuring device 2041 is thermoelectricity occasionally thermistor temperature detecting meter; Described surface temperature measurement device 2042 is the combination of one or more in infrared thermal imaging device, body surface coated with liquid crystal material, nuclear-magnetism thermal imaging temperature measuring equipment, microwave radiation temperature measuring device, velocity of sound temperature measuring equipment, ultrasonic temperature measurement device and CT temperature measuring equipment.Described computer operating system 100 receives the measurement data of self-heating physiological parameter monitoring module 204; generate cold control command according to this measurement data and be sent to hypothermia protection module 202 and kill and wound module 203 with low temperature, to adjust the duty that described hypothermia protection module 202 and low temperature kill and wound module 203.When temperature data measured by hot physiological parameter monitoring module 204 is in the normal value under therapeutic state, described hypothermia protection module 202 kills and wounds module 203 with low temperature and keeps work on hand state; When temperature data measured by hot physiological parameter monitoring module 204 is lower than normal value under therapeutic state, described hypothermia protection module 202 kills and wounds with low temperature the amount that module 203 reduces the cold that wide warm area refrigeration module 201 produces, thus the output of minimizing cold; When temperature data measured by hot physiological parameter monitoring module 204 is higher than normal value under therapeutic state, described hypothermia protection module 202 kills and wounds with low temperature the amount that module 203 increases the cold that wide warm area refrigeration module 201 produces, thus the output of increase cold.
Described wide warm area refrigeration module 201 comprises, at least three kinds in phase-change refrigerating plant, gas throttling refrigerating plant, semiconductor cooling device, immersion freezing type refrigerating plant, absorption type refrigerating unit, solid adsorption refrigerating plant, evaporation refrigeration device and gas swirl refrigerating device.
The refrigerant that described wide warm area refrigeration module 201 adopts is carbon dioxide, (mist is a kind of general name of refrigerant for liquid nitrogen, Freon series cold-producing medium, nitrous oxide, argon, mist, it is mixed by multiple gases, and refrigeration character is determined by gas component and proportioning.), hypothermic saline or thermoelectric material.
When the All-functional wide warm area low-temperature treatment equipment of the embodiment of the present invention is used in hypothermic anesthesia, hypothermia medical treatment, brain hypothermia resuscitation and brain protection process; temperature required a little less than body temperature; can according to refrigerating plant suitable in corresponding treatment thermal creep stress wide warm area refrigeration module 201, as semiconductor cooling device, evaporation refrigeration device etc.Now, enable suitable cold output device again according to enforcement occasion, as used body surface to cover refrigerating plant in hypothermic anesthesia with local hypothermia medical procedure; Insertion type cryogen device for casting and cryogenic gas injection apparatus is used in the medical treatment of whole body hypothermia, brain hypothermia resuscitation and brain protection process.
When the present invention is used in low temperature kill process, its topical therapeutic temperature, generally lower than 0 DEG C, minimumly reaches-180 DEG C.Now, suitable refrigerating plant and refrigeration working medium in wide warm area refrigeration module 201 is selected according to the details of focus.As treat conventional transdermal section, ophthalmology and otorhinolaryngology disease time, temperature-controllable is made as-40 DEG C ~ 0 DEG C, and refrigerating plant can select thermoelectric cooling unit, phase-change refrigerating plant, gas throttling refrigerating plant etc.; When treating various malignant tumor, the requirement of low temperature is more strict, and need control as-180 DEG C ~-100 DEG C, refrigerating plant can select gas throttling refrigerating plant, immersion freezing type refrigerating plant etc.After determining refrigerating plant, the histoorgan depended on according to focus and depth enable suitable cold output device, as when focus is positioned at body surface, can uses contact refrigeration device or spray refrigerating plant; When focus is positioned at human body natural's cavity, injecting type refrigerating plant or insertion type refrigerating plant can be used; When focus is positioned at human body deep, can uses and insert refrigerating plant or insertion type refrigerating plant.
When the present invention is used for the operation that clinical difficulty is higher, risk is larger, during as diseases such as tumors near neurosurgery intracranial Posterior circle giant aneurysm, basis cranii brain stem, first can enable in wide warm area refrigeration module 201 refrigerating plant and refrigeration working medium that can realize a little less than body temperature, thus realize the treatment of whole body Deep Hypothermia Circulatory Arrest; Enable refrigerating plant and the refrigeration working medium that killing tumor cells tissue temperature in wide warm area refrigeration module 201, can be realized again, and then destroy tumor tissues.Now, not only can realize the lethal effect of tumor tissues, can also realize the low-temperature protection of whole body vitals, surgical effect is better, and curative effect is more reliable.
Use the therapeutic equipment of the embodiment of the present invention, by computer operating system 100 and the first cold input control device 2021 and the second cold input control device 2031, refrigeration intensity and low temperature time are controlled in therapeutic process, and realize the monitoring of human body corresponding site single-point and surface temperature value by means of hot physiological parameter monitoring module 204.Described computer operating system 100 receives the measurement data of self-heating physiological parameter monitoring module 204, generate cold control command according to this measurement data and be sent to hypothermia protection module 202 and kill and wound module 203 with low temperature, to adjust the duty that described hypothermia protection module 202 and low temperature kill and wound module 203: when measured by hot physiological parameter monitoring module 204, temperature data is in the normal value under therapeutic state, described hypothermia protection module 202 kills and wounds module 203 with low temperature and keeps work on hand state; When temperature data measured by hot physiological parameter monitoring module 204 is lower than normal value under therapeutic state, described hypothermia protection module 202 kills and wounds with low temperature the amount that module 203 reduces the cold that wide warm area refrigeration module 201 produces, thus the output of minimizing cold; When temperature data measured by hot physiological parameter monitoring module 204 is higher than normal value under therapeutic state, described hypothermia protection module 202 kills and wounds with low temperature the amount that module 203 increases the cold that wide warm area refrigeration module 201 produces, thus the output of increase cold.Thus form a dynamic control process.
All-functional wide warm area low-temperature treatment equipment described in the embodiment of the present invention has following advantage.First, it is integrated with the refrigeration system had complementary functions on the same device first, mutually merge by phase-change refrigerating plant, gas throttling refrigerating plant, semiconductor cooling device, immersion freezing type refrigerating plant etc., select refrigerating plant and cryogenic temperature according to actual therapeutic situation; Secondly, described in the embodiment of the present invention hypothermia protection module 202 kill and wound in module 203 with low temperature and be configured with multiple cold output device simultaneously, utilize this therapeutic equipment can select suitable cold output device according to treatment situation, realize efficient low temperature therapy object; 3rd, this therapeutic equipment also can implement hypothermia protection and low temperature killing ability simultaneously, thus is applied to as in the diseases that clinical difficulty is high, operation risk is large such as tumor near neurosurgery intracranial Posterior circle giant aneurysm, basis cranii brain stem efficiently; Finally, it is in use more flexible that various traditional low temperature therapy equipment compared by therapeutic equipment described in the embodiment of the present invention, there is application scenario widely, also for medical personnel provide more easy instrumentation mode, thus overcome the deficiency of prior art existence to a certain extent.
Above embodiment is only for illustration of the present invention; and be not limitation of the present invention; the those of ordinary skill of relevant technical field; without departing from the spirit and scope of the present invention; can also make a variety of changes and modification; therefore all equivalent technical schemes also belong to category of the present invention, and scope of patent protection of the present invention should be defined by the claims.
Claims (8)
1. an All-functional wide warm area low-temperature treatment equipment, is characterized in that, comprising: computer operating system (100) and cryogenic process system (200); Described cryogenic process system (200) comprising: wide warm area refrigeration module (201), hypothermia protection module (202), low temperature kill and wound module (203) and hot physiological parameter monitoring module (204);
Described computer operating system (100), for receiving the temperature information that described hot physiological parameter monitoring module (204) sends, generate cold control command according to described temperature information, and be sent to described hypothermia protection module (202) and low temperature kills and wounds module (203);
Described wide warm area refrigeration module (201), connects described hypothermia protection module (202) and low temperature kills and wounds module (203), for generation of the cold needed for low temperature therapy;
Described hypothermia protection module (202), connect described computer operating system (100), for controlling the amount of the cold that described wide warm area refrigeration module (201) produces according to described cold control command, and export described cold and carry out hypothermia protection, described hypothermia protection module (202) comprising: the first cold input control device (2021) be connected to each other and the first cold output device (2022); Described first cold input control device (2021), in hypothermia protection process, controls the amount of the cold that described wide warm area refrigeration module (201) produces according to described cold control command; Described first cold output device (2022), for exporting the cold that described wide warm area refrigeration module (201) produces in hypothermia protection process; Described first cold output device (2022) comprises at least two kinds in body surface covering refrigerating plant, insertion type cryogen device for casting and cryogenic gas injection apparatus;
Described low temperature kills and wounds module (203), connect described computer operating system (100), for controlling the amount of the cold that described wide warm area refrigeration module (201) produces according to described cold control command, and export described cold and carry out low temperature and kill and wound;
Described hot physiological parameter monitoring module (204), for carrying out corresponding monitoring temperature, and is sent to described computer operating system (100) by the temperature information monitored.
2. therapeutic equipment as claimed in claim 1, it is characterized in that, described cryogenic process system (200) also comprises power module (205);
Described power module (205) is for being other each modules of described cryogenic process system (200) and described computer operating system (100) power supply.
3. therapeutic equipment as claimed in claim 1, it is characterized in that, described low temperature kills and wounds module (203) and comprising: the second cold input control device (2031) be connected to each other and the second cold output device (2032);
Described second cold input control device (2031), in low temperature kill process, according to the cold that the described wide warm area refrigeration module (201) of described cold control command control produces;
Described second cold output device (2032), for exporting the cold that described wide warm area refrigeration module (201) produces in low temperature kill process.
4. therapeutic equipment as claimed in claim 3, is characterized in that, described second cold output device (2032) comprises contact refrigeration device, insertion refrigerating plant, at least two kinds of spraying in refrigerating plant and insertion type refrigerating plant.
5. therapeutic equipment as claimed in claim 1, it is characterized in that, described hot physiological parameter monitoring module (204) comprises, for carrying out the single point temperature measuring device (2041) of single point temperature measurement, and for carrying out the surface temperature measurement device (2042) of surface temperature measurement, measurement data is all sent to described computer operating system (100) by described single point temperature measuring device (2041) and described surface temperature measurement device (2042).
6. therapeutic equipment as claimed in claim 1, it is characterized in that, described therapeutic equipment also comprises operating-table, and described cryogenic process system (200) is arranged on described operating-table.
7. therapeutic equipment as claimed in claim 1, it is characterized in that, described wide warm area refrigeration module (201) comprises at least three kinds in phase-change refrigerating plant, gas throttling refrigerating plant, semiconductor cooling device, immersion freezing type refrigerating plant, absorption type refrigerating unit, solid adsorption refrigerating plant, evaporation refrigeration device and gas swirl refrigerating device.
8. therapeutic equipment as claimed in claim 1, it is characterized in that, the refrigerant that described wide warm area refrigeration module (201) adopts is carbon dioxide, liquid nitrogen, Freon series cold-producing medium, nitrous oxide, argon, mist, hypothermic saline or thermoelectric material.
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Effective date of registration: 20181126 Address after: Room 3212, 3rd floor clubhouse, No. 18 East Zhongcun Road, Haidian District, Beijing Patentee after: Hejna (Beijing) medical instruments Co., Ltd. Address before: 100190 Beijing Haidian District Zhongguancun North No. 2 Patentee before: Technical Institute of Physics and Chemistry, CAS |
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