CN208447764U - A kind of compound ablation system of freezing microwave - Google Patents

A kind of compound ablation system of freezing microwave Download PDF

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Publication number
CN208447764U
CN208447764U CN201721221292.7U CN201721221292U CN208447764U CN 208447764 U CN208447764 U CN 208447764U CN 201721221292 U CN201721221292 U CN 201721221292U CN 208447764 U CN208447764 U CN 208447764U
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microwave
freezing
ablation
gas
solenoid valve
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刘剑鹏
崔佳星
杨光远
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Beijing Sunlight Yi Bang Medical Science And Technology Co Ltd
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Beijing Sunlight Yi Bang Medical Science And Technology Co Ltd
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Abstract

The utility model discloses a kind of compound ablation systems of freezing microwave, belong to technical field of medical equipment.The system comprises display equipment, host, input equipment, control panel, microwave power source, freezing control gas circuit, power supply, ablation needle, argon gas source and helium gas sources;Display equipment and input equipment are electrically connected with host respectively;Host is electrically connected with control panel;Control panel is electrically connected with microwave power source and ablation needle respectively;Microwave power source is electrically connected by cable with ablation needle;Argon gas source and helium gas source pass through air delivering pipeline respectively and connect with the air inlet of freezing control gas circuit;The gas outlet of freezing control gas circuit is connected by the air inlet of air delivering pipeline and ablation needle;Power supply is electrically connected with host, control panel and microwave power source respectively.The compound ablation system of freezing microwave provided by the utility model can make the case where doctor is for different patients, select cryoablation, microwave ablation or the freezing compound ablation mode of microwave.

Description

A kind of compound ablation system of freezing microwave
Technical field
The utility model relates to technical field of medical equipment, the in particular to a kind of compound ablation system of freezing microwave.
Background technique
The case that tumour is suffered from China and the world in recent years sharply rises.By taking liver cancer as an example, according to the statistics of the World Health Organization, cut Only there are about 400,000,000 chronic hepatitis Bs and hepatitis C infections person for the whole world in 2014, and there are about 1,400,000 people to die of hepatites virus infections, liver cancer every year There is 80% to be caused in death by hepatitis B and hepatitis.The existing chronic hepatitis B of China and hepatitis C infections person account for the whole world four/ One, liver cancer case accounts for global half.China is high liver cancer incidence area, morbidity and the death rate especially male be located at the world compared with High level.Although the morbidity of liver cancer and the death rate are relatively stable in recent years, survival rate is located at world's higher level, but still relatively It is low.It is expected that the onset of liver cancer and the death rate of future world and China will continue growing.
Currently, there are many kinds of the methods for the treatment of cancer, it is main to disappear including operation excision, interventional therapy, drug therapy, part Melt treatment etc..For last decade with the appearance of various ablation Medical Devices, local ablation therapy has obtained quick development, clinical Mainly there are three kinds of RF ablation (RFA), microwave ablation (MWA) and cryoablation (Cryoablation, cryoprobe) using upper.Office Portion's ablation method has the characteristics that wound is small, treatment is accurate, it is fast to restore, operation risk is low and low-cost.Local ablation Treatment according to its treat principle be divided into cold ablation and heating ablation (RF ablation and microwave ablation belong to heating ablation scope, but due to The heating speed of microwave is fast, and ablation range is big, and operation convenience relatively gradually has the tendency that banning RF ablation).Disappear compared to heat Melt, cryoablation has the advantages that
1) working principle of heating ablation operation is so that protein coagulating is even carbonized and reach inactivation mesh cancerous issue calcination , temperature is even higher up to 100 DEG C, and patient may feel that very pain, poor resistance;And in cryoablation surgical procedure In, since freezing itself has the function of analgesic, patient does not have the feeling of severe pain.
2) the inactivation range of heating ablation only has 2cm or so, and solid tumor of such diameter greater than 2cm can not all be gone out It is living, lead to high recurrence rate, and since its principle is limited, it is more difficult to realize that spininess is used in combination.And cryoablation can inactivate directly The solid tumor of diameter 2cm or more, and can be used in combination with spininess, keep inactivation range bigger, can achieve heating ablation inactivation 5~6 times of range.
3) if knub position is close to blood vessel, heating ablation is not available for treating;The reason is that, heating ablation can be by blood vessel calcination Perforation, leads to big bleeding.And cryoablation can carry out ablation to the tumour beside blood vessel, since blood vessel is by connective tissue Tolerance low temperature is constituted, therefore cryoablation can be carried out.If knub position disappears close to the tumour at abdominal cavity edge or diaphram, heat Melt and is not available for treating, and cryoablation can treat.It can be seen that the indication range of cryoablation is wider.
4) cryoablation has immunology effect: freezing disturbs the biological activity of oncocytology and remains tumour The immune response of specificity antineoplastic can be improved in the structure of antigen protein, while ablation tissue liquefaction is easy to sponge.And Heating ablation is that indifference ablation can make tissue protein solidification even " carbonization " improve the immune response of specificity antineoplastic not Significantly, while carbide texture caused by heating ablation is difficult to absorb, and patient has the presence of foreign body sensation and non-infectious inflammation for a long time.
Although cryoablation have many advantages, such as it is above-mentioned, cryoablation have certain ablation needle gastrointestinal hemorrhage risk, it is cold Only can be by temperature rewarming to 40 DEG C when freezing rewarming, cannot making blood coagulating protein coagulation, (protein coagulating temperature is usually 57 ℃).And heating ablation, when being performed the operation, temperature can reach 90 DEG C or more, and blood coagulating protein can be made to solidify, and play the role of hemostasis. Therefore, how to make full use of the advantages of cryoablation and heating ablation, so as to it is safer, treat tumour to a greater extent, be medical treatment The problem of technical staff pays special attention to.
Utility model content
In order to solve the limitation that cryoablation and microwave ablation are individually present, it is micro- that the utility model provides a kind of freezing The compound ablation system of wave, including display equipment, host, input equipment, control panel, microwave power source, freezing control gas circuit, electricity Source, ablation needle, argon gas source and helium gas source;The display equipment and the input equipment are electrically connected with the host respectively;It is described Host is electrically connected with the control panel;The control panel is electrically connected with the microwave power source and the ablation needle respectively;It is described Microwave power source is electrically connected by cable with the ablation needle;The argon gas source and helium gas source pass through respectively air delivering pipeline with it is described The air inlet connection of freezing control gas circuit;The gas outlet of the freezing control gas circuit by air delivering pipeline and the ablation needle into Port connection;The power supply is electrically connected with the host, the control panel and the microwave power source respectively.
The freezing control gas circuit includes relay, first filter, the first safety valve, the first solenoid valve, the second filtering Device, the second safety valve, second solenoid valve, third solenoid valve and gas distribute branch;The output end of the control panel and it is described after The input terminal of electric appliance is electrically connected, the output end of the relay respectively with the first solenoid valve, second solenoid valve, described Third solenoid valve and gas distribution branch electrical connection;The entrance of the first filter passes through air delivering pipeline and the argon gas Source connection, the outlet of the first filter is connect with the arrival end of first safety valve;The outlet of first safety valve End is connect with the arrival end of first solenoid valve;The entrance of the outlet end of first solenoid valve and gas distribution branch End connection;The entrance of second filter is connect by air delivering pipeline with the helium gas source, the outlet of second filter It is connect with the arrival end of second safety valve;The outlet end of second safety valve and the arrival end of the second solenoid valve connect It connects, the outlet end of the second solenoid valve is connect with the arrival end of gas distribution branch;The gas distribution branch goes out Mouth end is connect with the air inlet of the ablation needle;The outlet end of the arrival end of the third solenoid valve and first safety valve connects It connects;The outlet end of the third solenoid valve connects exhaust outlet.
The gas distribution branch routes multiple gas distribution members parallel with one another and constitutes;The gas distribution member includes First gas distributes solenoid valve, second gas distribution solenoid valve, cooling gas check valve and gas and distributes filter;The first gas The arrival end of distribution solenoid valve is connect with the outlet end of the arrival end of the cooling gas check valve and first solenoid valve respectively;Institute The arrival end of second gas distribution solenoid valve is stated to go out with the outlet end of the cooling gas check valve and the second solenoid valve respectively The connection of mouth end;The outlet of the first gas distribution solenoid valve and second gas distribution solenoid valve and the gas distributed The arrival end of filter connects;The outlet end of the gas distribution filter is connect with the air inlet of the ablation needle.
The ablation needle include needle ontology, snorkel, radiation head, felt pad, transmission cable, thermal insulation layer, shell, handle and Thermocouple;The tip of the snorkel is provided with throttle orifice;The needle ontology and the cage connection;The inner wall of the shell is set It is equipped with the thermal insulation layer;The tail end of the shell is connect with the handle;The snorkel is arranged in parallel with the transmission cable In the shell, and extend in the handle;The radiation head is set at the tip of the needle ontology, and with it is described Transmission cable connection;The junction of the transmission cable and the radiation head is provided with the felt pad;The thermocouple setting In in the shell.
The control panel include central controller, A/D converter, the first temperature acquisition interface, multi-channel PWM output module, Communication module and PID modulator;The first temperature acquisition interface is electrically connected with the thermocouple;First temperature acquisition connects Mouth is electrically connected with the A/D converter;The A/D converter is electrically connected with the central controller;The PID modulator difference It is electrically connected with the central controller and the microwave power source;The communication module respectively with the central controller and described Host electrical connection;The multi-channel PWM output module is electrically connected with the central controller and the relay respectively.
Further, the system also includes thermoprobe, the thermoprobe is electrically connected with the control panel.
Further, the control panel further includes second temperature acquisition interface;The second temperature acquisition interface respectively with The thermoprobe and A/D converter electrical connection.
The microwave power source includes the first microwave power source and the second microwave power source;First microwave power source Frequency is 915MHz, and the frequency of second microwave power source is 2450MHz.
The input equipment includes keyboard or mouse.
The display equipment includes liquid crystal display or touch liquid crystal display.
The compound ablation system of freezing microwave provided by the utility model can make the case where doctor is for different patients, selection Cryoablation, microwave ablation or the freezing compound ablation of microwave, realize the Integration Design of cryoablation and microwave ablation, reduce The purchase cost of ablation apparatus, easy to use, high degree of automation significantly reduce expenses of surgical treatment, greatly push away Into the fast development of Minimally Invasive Surgery.The compound ablation system of freezing microwave provided by the utility model, can be to the temperature of ablation needle It is accurately controlled, injury normal tissue not only can be prevented, but also can avoid tumour cell and be seriously carbonized.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model embodiment freezing compound ablation system of microwave;
Fig. 2 is the structural schematic diagram of the utility model embodiment ablation needle;
Fig. 3 is the application implementation of the utility model embodiment freezing compound ablation system of microwave;
Fig. 4 is the structural schematic diagram of the utility model embodiment control panel;
Fig. 5 is the composition schematic diagram of the utility model embodiment PID modulator.
Specific embodiment
With reference to the accompanying drawings and examples, technical solutions of the utility model are further described.
Cryoablation technology has been widely used in the diseases such as clinical treatment tumour.Cryoablation technology belongs to pure physics and controls It treats, so that target area is reached -150 DEG C, then be rapidly heated to 40 DEG C, wipe out tumour cell, therapeutic effect is definite, will not lead Carcinogenic cells diffusion, the minimally invasive no pain of process restore fast, do not damage normal tissue, have no toxic side effect, improve antineoplastic immune because Son.Existing cryoprobe utilizes Joule-Thomson principle, and cryoprobe is inserted into position to be treated and is treated, high pressure argon Gas achievees the purpose that fast-refrigerating by the throttling of the throttle orifice of probe interior front end, then is reached by high-pressure helium and be rapidly heated Purpose.
Microwave ablation techniques be a kind of pair of tumor tissues have efficiently, quickly, be evenly heated, thermocoagulation thoroughly, user Just, safe treatment method, is widely used to clinic for many years.It is by the microwave needle of a Gent, percutaneous puncture to tumour Central area, " miniature micro-wave oven " containing 1 mm in size on the certain point of microwave needle, the microwave magnetic field discharged by it It can make the molecule high speed rotary motion of surrounding and friction generates heat;When temperature is increased to 60 DEG C or more, tumour cell Protein denaturation solidification, changes environment locating for tumour cell, and it is downright bad to lead to its irreversibility, to make tissue coagulation, dehydration Necrosis achievees the purpose that treatment.Simultaneously as the heat that microwave ablation generates can make protein coagulating, there is hemostasis well Effect.
Referring to Fig. 1, the advantages of the utility model embodiment utilizes cryoablation and microwave ablation, providing one kind can be into The system that row cryoablation can carry out microwave ablation again, in order to make the case where doctor is for different patients, select cryoablation, Microwave ablation or the freezing compound ablation of microwave.The compound ablation system of freezing microwave provided by the embodiment of the utility model includes display Equipment 1, input equipment 2, host 3, control panel 4, microwave power source 5, freezing control gas circuit 6, power supply 7, ablation needle 8, argon gas source 9 With helium gas source 10.Wherein, show that equipment 1 and input equipment 2 are electrically connected with host 3 respectively;Host 3 is electrically connected with control panel 4;Control Making sheet 4 is electrically connected with microwave power source 5 and ablation needle 8 respectively;Microwave power source 5 is electrically connected by cable with ablation needle 8;Argon gas Source 9 and helium gas source 10 are connect by air delivering pipeline with the air inlet of freezing control gas circuit 6 respectively;The outlet of freezing control gas circuit 6 Mouth is connect by air delivering pipeline with the air inlet of ablation needle 8;Power supply 7 is electrically connected with host 3, control panel 4 and microwave power source 5 respectively It connects.
Referring to Fig. 1, the utility model embodiment freezing control gas circuit 6 includes relay 601, filter 602, safety valve 603, solenoid valve 604, filter 605, safety valve 606, solenoid valve 607, solenoid valve 608 and gas distribute branch;Control panel 4 Output end is electrically connected with the input terminal of relay 601, the output end of relay 601 respectively with solenoid valve 604, solenoid valve 607, electricity Magnet valve 608 and gas distribution branch electrical connection;The entrance of filter 602 is connect by air delivering pipeline with argon gas source 9, filter 602 outlet is connect with the arrival end of safety valve 603;The outlet end of safety valve 603 is connect with the arrival end of solenoid valve 604;Electricity The outlet end of magnet valve 604 is connect with the arrival end of gas distribution branch;The entrance of filter 605 passes through air delivering pipeline and helium gas source 10 connections, the outlet of filter 605 is connect with the arrival end of safety valve 606;The outlet end of safety valve 606 and solenoid valve 607 The outlet end of arrival end connection, solenoid valve 607 is connect with the arrival end of gas distribution branch;Gas distribute branch outlet end with The air inlet of ablation needle 8 connects;The arrival end of solenoid valve 608 is connect with the outlet end of safety valve 603;The outlet of solenoid valve 608 End connection exhaust outlet.Further, the gas distribution branch of the present embodiment routes multiple gas distribution members parallel with one another and constitutes, Each gas distribution member includes gas distribution solenoid valve 609, gas distribution solenoid valve 610, cooling gas check valve 611 and gas point With filter 612;Gas distribute the arrival end of solenoid valve 609 respectively with the arrival end of cooling gas check valve 611 and solenoid valve 604 Outlet end connection;Gas distribute the arrival end of solenoid valve 610 respectively with the outlet end of cooling gas check valve 611 and solenoid valve 607 Outlet end connection;The outlet of gas distribution solenoid valve 609 and gas distribution solenoid valve 610 enters with gas distribution filter 612 The connection of mouth end;The outlet end of gas distribution filter 612 is connect with the air inlet of ablation needle 8.In practical applications, filter 602, filter 605 and gas distribution filter 612 are used to impurity and steam in filtering gas.It should be understood that being It realizes and ablation needle temperature is accurately controlled, avoid the injury of normal tissue, gas distribution branch should use 8 tunnels, 10 tunnels Or 12 multichannels gas distribution channel such as tunnel;For example, the present embodiment uses 8 road gas distribution channels, by control panel 4 to 8 road gas distribution channels Solenoid valve carries out alternately control, realizes the adjusting of freezing power, and then accurately controls the temperature of ablation needle 8.
Referring to fig. 2, the ablation needle 8 of the utility model embodiment has the function of freezing and microwave radiation, including needle ontology 81, snorkel 82, radiation head 83, felt pad 84, transmission cable 85, thermal insulation layer 86, shell 87, handle 88 and thermocouple 89.Its In, the tip of snorkel 82 is provided with throttle orifice;Needle ontology 81 is connect with shell 87;The inner wall of shell 87 is provided with thermal insulation layer 86;The tail end of shell 87 is connect with handle 88;Snorkel 82 and transmission cable 85 are arranged in parallel in shell 87, and extend to hand In handle 88;Radiation head 83 is set at the tip of needle ontology 81, and is connect with transmission cable 85;Transmission cable 85 and radiation head 83 junction is provided with felt pad 84;Thermocouple 89 is set in shell 87.Ablation needle 8 both can be using Joule-Thomson Principle carries out cryoablation, can also carry out heating ablation by microwave.For ablation needle 8 when being freezed, high pressure argon gas is in ablation needle Point throttle effect occurs, generate cooling capacity, reflux gas flows back out of ablation needle;When carrying out microwave heating, power source It is transferred to radiation head 83, the part between the tip of needle ontology 81 is arrived to felt pad 84 causes tissue element hot to external radiation Movement generates heat.Thermocouple 89 for acquiring the temperature inside ablation needle 8 in real time.Thermal insulation layer 86 can prevent 87 frostbite of shell Or normal tissue of burning.
Referring to fig. 4, the utility model embodiment control panel 4 is adopted including central controller MCU41, A/D converter 42, temperature Collect interface 43, multi-channel PWM output module 44, communication module 45 and PID modulator 46.Wherein, temperature acquisition interface 43 and thermoelectricity Even 89 are electrically connected;Temperature acquisition interface 43 is electrically connected with A/D converter 42;A/D converter 42 is electrically connected with central controller 41; PID modulator 46 is electrically connected with central controller 41 and microwave power source 5 respectively;Communication module 45 respectively with central controller 41 It is electrically connected with host 3;Multi-channel PWM output module 44 is electrically connected with central controller 41 and relay 601 respectively.
In practical applications, microwave power source 5 includes microwave power source 51 and microwave power source 52, as shown in Figure 1;Microwave The frequency of power source 51 is 915MHz, and the frequency of microwave power source 52 is 2450MHz;Doctor can select according to different lesions Select the microwave power source of different frequency.Show that equipment 1 may include liquid crystal display or touch liquid crystal display etc., for showing Freezing state, freezing power, time, ablation needle temperature, real-time working air pressure, microwave frequency selection, microwave power, false alarm Etc. system informations.Input equipment 3 may include keyboard or mouse etc., and the service aisle different for doctor's operation unlatching, adjusting are cold Freeze power, selection rewarming mode, selection microwave frequency, selection microwave power etc..
In addition, the compound ablation system of freezing microwave provided by the embodiment of the utility model can also further comprise thermoprobe 11, thermoprobe 11 is electrically connected with control panel 4, for measuring the temperature of cryoablation or microwave ablation range, and then is monitored cold Jelly or heating ablation regional temperature avoid the injury of normal tissue and determine ablation range.Correspondingly, control panel 4 further wraps Temperature acquisition interface 47 is included, temperature acquisition interface 47 is electrically connected with thermoprobe 11 and A/D converter 42 respectively.
In practical applications, T-type thermocouple can be used in thermoprobe 11.It should be understood that in order to more accurately sentence The temperature of disconnected cryoablation or microwave ablation range can use 8 tunnels, 10 tunnels or 12 tunnels to avoid the injury of normal tissue The mode of equal multichannel temperature measurements;For example, the present embodiment selects 8 tunnel temperature measurement methods, i.e., constituted using 8 T-type thermocouples Thermoprobe, 8 T-type thermocouples are separately positioned on the different location of cryoablation or microwave ablation range, to realize multiple spot Temperature monitoring.
Referring to Fig. 3, the compound ablation system of freezing microwave provided by the embodiment of the utility model has multiple-working mode.? Before doctor implements operation, the concrete condition according to ablation lesion is needed, cryoablation, microwave ablation or both is selected to combine Compound ablation mode.The working principle of above-mentioned three kinds of operating modes is simply summarized below:
1) cryoablation mode: low temperature can be generated after throttling using high pressure argon gas, and can generate liter after high-pressure helium throttling The physical characteristic of temperature;Gas (argon gas and helium) enters ablation needle 8 after flowing through freezing control gas circuit 6, in the tip of ablation needle 8 position Set generation throttle effect.For the utility model embodiment when controlling cryoablation, control panel 4 receives input equipment 2 by host 3 The operational order issued, control relay 601 is turned on and off, and then relay 601 controls solenoid valve 604 or solenoid valve 607 On-off, realize control to gas on-off.The cryoablation mode of the utility model embodiment has adjustment freezing power Function, specific implementation are the make-and-break times of the adjusting solenoid valve within an electromagnetic valve work period, such as: it is within setting 5 seconds The duty cycle of one solenoid valve, setting is by 0%~100%, stepped intervals 5%, totally 20 different power grades;If The freezing power of selection 5%, as 1/20 electromagnetic valve work period, as 0.25 second, then in 5 seconds electromagnetic valve work In period, relay 601 will be opened 0.25 second, be closed 4.75 seconds, and control solenoid valve is ventilated 0.25 second, closed 4.75 seconds.
2) microwave ablation mode: the utility model embodiment integrates two independent microwave power sources, i.e. microwave power source 51 and microwave power source 52, output frequency be respectively 915MHz and 2450MHz, two power sources are that 0~300 watt of dynamic is adjustable Type.Microwave power source exports the microwave of 915MHz or 2450MHz frequency, is transmitted through the cable to ablation needle 8, in ablation needle 8 Radiation head can make the overturning of the molecule near its tip location, and friction generates heat.It is melted with different frequency, therapeutic effect is not Together;915MHz can reach bigger ablated volume, and 2450MHz heating rate is faster.Doctor can according to the different situations of patient, Select " quick mode " of 2450MHz or " general modfel " of 915MHz.The utility model embodiment is that doctor sets " certainly It is dynamic " and " manual " two kinds of working methods;When selection " automatic " working method, doctor can be according to puncture position, size of tumor, week It encloses tissue etc. to set the process of ablation, i.e. setting microwave time, power, the parameters such as temperature, system is according to the work of setting Make process and carries out microwave ablation;When selection " manual " working method, doctor can pass through CT or the focal ablation of color ultrasound reflection Degree and display on ablation needle temperature, in real time adjust microwave power source power.During microwave ablation, pass through PID modulator carries out adaptive dynamic power adjusting, realizes and carries out accurate temperature control to ablation needle, to prevent temperature excessively high The adhesion of caused carbonized and ablation tissue and ablation needle, ablation caused by overcoming temperature too low are not thorough;Doctor according to Different lesions is controlled using different accurate temperature, as shown in Figure 4: inside the ablation needle that A/D converter acquires thermocouple Temperature value be converted into digital signal, and PID modulator is given in output after central controller MCU processing;PID modulator will be adjusted Signal processed is sent to microwave power source;Microwave power source adjusts output power according to the modulated signal received.PID modulator by than Example unit P, integral unit I and differentiation element D composition, as shown in Figure 5;Proportional unit P adjusts temperature controlled degree of error, Kp number Value is bigger, and error is smaller, but will lead to system response time lengthening, so integral unit I is needed to increase response speed, while benefit It is filtered with differentiation element D, three parameter Kp、KiAnd KdIt complements each other, is precisely controlled to reach optimal temperature.
In practical applications, since ablation needle individual itself has differences and ablation locations are different, it will lead to and disappear Melt that needle load is different, this just needs to adjust the parameter of PID modulator.By many experiments early period, research finds that microwave disappears When melting heating, the heating rate of ablation needle can reflect its performance difference and load difference.Accordingly, the utility model embodiment is logical The heating rate for spending 30 seconds before acquiring microwave ablation, calculates three optimal parameters of PID modulator.Choose different heating rates Ablation needle tested, collect experimental data, carry out three parameters data fitting.Set initial 30 seconds heating rates as V, i.e. V are equal to temperature inversion value Δ TemDivided by time t (t is equal to 30 seconds), three pre-set parameters of PID modulator are Kp、Ki And Kd, using secondary power, the method for three supplemental characteristics fitting, empirical curve is returned, and then find out three parameters is Number, if its coefficient is (AP1, AP2, AP3), (Ai1, Ai2, Ai3), (Ad1, Ad2, Ad3), then
It is fitted by 2 power data, has found out the coefficient of correspondence of three parameters of PID modulator.It heated up carrying out microwave Cheng Zhong finds out three parameter value K of corresponding optimal PID modulator according to 30 seconds before ablation needle rate of temperature fall Vp、KiWith Kd
Since ablation needle is there are individual configurations difference, heating rate is different.Doctor can only be passed through at the time of surgery, Raw subjective judgement manually adjusts microwave power source power.And perform the operation for microwave ablation, the temperature of ablation needle has very big Meaning.Due to microwave heating rate quickly, up to a hundred degrees Celsius of high temperature can be reached in tens seconds, if temperature is excessively high, no It will result only in tumour perienchyma scald, also result in tumour cell and be seriously carbonized, patient has serious feeling of pain, and tight The tissue being carbonized again, body are difficult to absorb, and patient has foreign body sensation, it is possible to create the adverse reactions such as repulsion.The present embodiment center Controller calculates optimal pid parameter according to the temperature value inside the ablation needle of acquisition, and the parameter is exported and gives PID tune Device, and then the output power of dynamic regulation microwave power source are saved, realization is precisely controlled microwave ablation temperature, not only may be used in this way To prevent injury normal tissue, but also it can avoid tumour cell and be seriously carbonized.
3) freeze the compound ablation mode of microwave: the utility model embodiment is by the means using freezing as cell inactivation, again Lesion is carried out secondary inactivation, while can also stopped blooding for needle track by applied microwave when warm.This operating mode, which can effectively improve, to disappear The whole inactivation ratio melted reduces the risk of residual activity and tissue transfer.
When melting beginning, doctor's operation input equipment chooses three kinds of different operating modes (cryoablations, microwave ablation Or the freezing compound ablation of microwave).In cryoablation, gas is passed through ablation needle through solenoid valve by gas cylinder and realizes refrigeration;Control panel The instruction that input equipment issues is received by host, controls relay, and then control solenoid valve on-off, realization is passed through gas Control;Meanwhile by adjusting the opening and closing time of solenoid valve, refrigeration work consumption is adjusted;The inside of ablation needle has thermocouple, Control panel carries out temperature acquisition to it, and is transferred to host, and then the real time temperature of ablation needle is shown on the display device.? When microwave ablation, doctor can choose " quick mode " or " general modfel " according to different lesion situations;" quick mode " is using defeated Frequency is the microwave power source of 2450MHz out, and " general modfel " uses output frequency for the microwave power source of 915MHz;Two kinds of works Operation mode all has " automatic " and " manual " working method.In the compound ablation of freezing microwave, the ablation needle of the present embodiment is not only It can be worked, but also can be worked with microwave mode with freezing mode;When freezing, the present embodiment system is realized by gas throttling and is made It is cold;When rewarming, the present embodiment exports microwave signal using microwave power source, and can increase rewarming time;What is stopped blooding for needle track Meanwhile can also secondary ablation be carried out to needle path, prevent needle track implantation from shifting.
The compound ablation system of freezing microwave provided by the embodiment of the utility model can make doctor be directed to the feelings of different patients Condition selects cryoablation, microwave ablation or the freezing compound ablation of microwave.Such as patient tumors are located proximate to big blood vessel, such as with micro- The heating ablations mode such as wave, radio frequency, meeting injuring tumor periphery blood vessel lead to big bleeding, and doctor uses the utility model embodiment System, may be selected cryoablation mode tumour can be subjected to ablation inactivation under the premise of not damaging blood vessel;In another example When treating hemangioma, because its blood supply is abundant, cryoablation is such as applied, has bleeding risk, and doctor is real using the utility model Microwave ablation mode can be selected in the system for applying example, while treatment, can achieve the effect of hemostasis.In addition, doctor uses this The system of utility model embodiment may be selected the freezing compound ablation mode of microwave, be melted using freezing, and applied microwave carries out Needle track hemostasis and the secondary ablation of needle track, hemostasis while, can also prevent Implantation matastasis.Freezing provided by the embodiment of the utility model The compound ablation system of microwave, realizes the Integration Design of cryoablation and microwave ablation, reduce the buying of ablation apparatus at This, easy to use, high degree of automation significantly reduces expenses of surgical treatment, greatly advances the quick of Minimally Invasive Surgery Development.
Particular embodiments described above has carried out into one the purpose of this utility model, technical scheme and beneficial effects Step is described in detail, it should be understood that being not limited to this foregoing is merely specific embodiment of the utility model Utility model, within the spirit and principle of the utility model, any modification, equivalent substitution, improvement and etc. done should all wrap Containing being within the protection scope of the utility model.

Claims (10)

1. a kind of compound ablation system of freezing microwave, which is characterized in that including display equipment, host, input equipment, control panel, Microwave power source, freezing control gas circuit, power supply, ablation needle, argon gas source and helium gas source;The display equipment and the input equipment It is electrically connected respectively with the host;The host is electrically connected with the control panel;The control panel respectively with the microwave power Source and ablation needle electrical connection;The microwave power source is electrically connected by cable with the ablation needle;The argon gas source and helium Gas source passes through air delivering pipeline respectively and connect with the air inlet of the freezing control gas circuit;The gas outlet of the freezing control gas circuit is logical Air delivering pipeline is crossed to connect with the air inlet of the ablation needle;The power supply respectively with the host, the control panel and described micro- The electrical connection of wave power source.
2. the freezing compound ablation system of microwave as described in claim 1, which is characterized in that the freezing control gas circuit include after Electric appliance, first filter, the first safety valve, the first solenoid valve, the second filter, the second safety valve, second solenoid valve, third electricity Magnet valve and gas distribute branch;The output end of the control panel is electrically connected with the input terminal of the relay, the relay Output end is electric with first solenoid valve, the second solenoid valve, the third solenoid valve and the gas distribution branch respectively Connection;The entrance of the first filter is connect by air delivering pipeline with the argon gas source, the outlet of the first filter and The arrival end of first safety valve connects;The arrival end of the outlet end of first safety valve and first solenoid valve connects It connects;The outlet end of first solenoid valve is connect with the arrival end of gas distribution branch;The entrance of second filter It is connect by air delivering pipeline with the helium gas source, the outlet of second filter connects with the arrival end of second safety valve It connects;The outlet end of second safety valve is connect with the arrival end of the second solenoid valve, the outlet end of the second solenoid valve It is connect with the arrival end of gas distribution branch;The outlet end of the gas distribution branch and the air inlet of the ablation needle connect It connects;The arrival end of the third solenoid valve is connect with the outlet end of first safety valve;The outlet end of the third solenoid valve Connect exhaust outlet.
3. the freezing compound ablation system of microwave as claimed in claim 2, which is characterized in that the gas distribution branch routing is multiple Gas distribution member parallel with one another is constituted;The gas distribution member includes first gas distribution solenoid valve, second gas point Filter is distributed with solenoid valve, cooling gas check valve and gas;The arrival end of first gas distribution solenoid valve respectively with it is described The arrival end of cooling gas check valve is connected with the outlet end of first solenoid valve;The arrival end of the second gas distribution solenoid valve It is connect respectively with the outlet end of the outlet end of the cooling gas check valve and the second solenoid valve;The first gas distributes electromagnetism The outlet of valve and second gas distribution solenoid valve is connect with the arrival end of gas distribution filter;The gas distribution The outlet end of filter is connect with the air inlet of the ablation needle.
4. as claimed in claim 3 freezing the compound ablation system of microwave, which is characterized in that the ablation needle include needle ontology, Snorkel, radiation head, felt pad, transmission cable, thermal insulation layer, shell, handle and thermocouple;The tip of the snorkel is provided with Throttle orifice;The needle ontology and the cage connection;The inner wall of the shell is provided with the thermal insulation layer;The tail end of the shell It is connect with the handle;The snorkel and the transmission cable are arranged in parallel in the shell, and extend to the handle It is interior;The radiation head is set at the tip of the needle ontology, and connect with the transmission cable;The transmission cable and institute The junction for stating radiation head is provided with the felt pad;The thermocouple is set in the shell.
5. the freezing compound ablation system of microwave as claimed in claim 4, which is characterized in that the control panel includes center control Device, A/D converter, the first temperature acquisition interface, multi-channel PWM output module, communication module and PID modulator;First temperature Degree acquisition interface is electrically connected with the thermocouple;The first temperature acquisition interface is electrically connected with the A/D converter;The A/ D converter is electrically connected with the central controller;The PID modulator respectively with the central controller and the microwave power Source electrical connection;The communication module is electrically connected with the central controller and the host respectively;The multi-channel PWM output module It is electrically connected respectively with the central controller and the relay.
6. the freezing compound ablation system of microwave as claimed in claim 5, which is characterized in that the system also includes thermometric spies Needle, the thermoprobe are electrically connected with the control panel.
7. the freezing compound ablation system of microwave as claimed in claim 6, which is characterized in that the control panel further includes the second temperature Spend acquisition interface;The second temperature acquisition interface is electrically connected with the thermoprobe and the A/D converter respectively.
8. the compound ablation system of freezing microwave as described in claim 5 or 7, which is characterized in that the microwave power source includes First microwave power source and the second microwave power source;The frequency of first microwave power source is 915MHz, second microwave The frequency of power source is 2450MHz.
9. the compound ablation system of freezing microwave as described in claim 5 or 7, which is characterized in that the input equipment includes key Disk or mouse.
10. the compound ablation system of freezing microwave as described in claim 5 or 7, which is characterized in that the display equipment includes liquid Crystal display screen or touch liquid crystal display.
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107485443A (en) * 2017-09-21 2017-12-19 北京阳光易帮医疗科技有限公司 One kind freezing compound ablation system of microwave
CN111643178A (en) * 2019-05-20 2020-09-11 上海申赞科贸有限公司 Tumor ablation cold-hot alternate treatment equipment
CN111671512A (en) * 2020-06-18 2020-09-18 沈阳鹏悦科技有限公司 Freezing electricity blocking system
CN112263321A (en) * 2020-06-23 2021-01-26 上海微创电生理医疗科技股份有限公司 Cryoablation temperature control method, system and medium
CN113081230A (en) * 2021-03-23 2021-07-09 上海导向医疗系统有限公司 Temperature measurement and rewarming integrated device and cryotherapy system

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107485443A (en) * 2017-09-21 2017-12-19 北京阳光易帮医疗科技有限公司 One kind freezing compound ablation system of microwave
CN111643178A (en) * 2019-05-20 2020-09-11 上海申赞科贸有限公司 Tumor ablation cold-hot alternate treatment equipment
CN111671512A (en) * 2020-06-18 2020-09-18 沈阳鹏悦科技有限公司 Freezing electricity blocking system
CN111671512B (en) * 2020-06-18 2024-02-09 沈阳鹏悦科技有限公司 Freezing electricity blocking system
CN112263321A (en) * 2020-06-23 2021-01-26 上海微创电生理医疗科技股份有限公司 Cryoablation temperature control method, system and medium
CN112263321B (en) * 2020-06-23 2022-04-01 上海微创电生理医疗科技股份有限公司 Cryoablation temperature control method, system and medium
CN113081230A (en) * 2021-03-23 2021-07-09 上海导向医疗系统有限公司 Temperature measurement and rewarming integrated device and cryotherapy system

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