CN100518684C - Cold circulation microwave tumor therapeutic apparatus - Google Patents

Cold circulation microwave tumor therapeutic apparatus Download PDF

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CN100518684C
CN100518684C CN 200610085783 CN200610085783A CN100518684C CN 100518684 C CN100518684 C CN 100518684C CN 200610085783 CN200610085783 CN 200610085783 CN 200610085783 A CN200610085783 A CN 200610085783A CN 100518684 C CN100518684 C CN 100518684C
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microwave
circuit
control
puncture needle
needle
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CN 200610085783
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CN1868415A (en
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宁 舒
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南京福中信息产业集团有限公司
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Abstract

本发明涉及一种冷循环微波肿瘤治疗仪,属于医疗设备技术领域。 The present invention relates to a refrigeration cycle apparatus Microwave tumor therapy, a medical technical field devices. 该治疗仪由主机、穿刺针、冷却系统、以及测温装置构成。 The treatment device is constituted by the host, the puncture needle, a cooling system, and a temperature measuring device. 测温装置至少含有二只独立分布的热敏电阻,其中之一安置在病灶附近,另一安置在穿刺针的针杆上,穿刺针的微波发生电路含有电压调控电路,冷却系统含有流量控制器件,热敏电阻的信号输出端分别接微处理芯片的对应输入端,微处理芯片的第一控制输出端接穿刺针的微波发生电路的电压调控电路,第二控制输出端接冷却系统的流量控制器件。 Thermistor temperature measuring device comprising at least two independent distribution, which is disposed in the vicinity of one of the lesions, a further needle shaft disposed in the puncture needle, the puncture needle microwave generating circuit comprising a voltage regulation circuit, the cooling system comprising flow control device , the thermistor signal output terminal respectively connected to the corresponding input terminal of the microprocessor chip, the voltage regulation circuit controlling the first circuit, the output end of the puncture needle microwave microchips occurs, the control flow of the second output end of the cooling system control devices. 采用本发明后,可以准确监控病灶与皮肤处的温度,通过对输出电压与冷却液流量的控制,形成理想的温度场,在热凝肿瘤组织的同时,避免灼伤皮肤等正常组织,达到最佳的治疗效果。 With the present invention, can accurately monitor the temperature at the skin lesions and by controlling the output voltage of the coolant flow and temperature to form the desired field, while the thermosetting tumor tissue, normal tissue such as skin burns avoided, optimal the therapeutic effect.

Description

冷循环微波肿瘤治疗仪 Cool microwave Tumor Treatment

技术领域 FIELD

本发明涉及一种治疗仪,尤其是一种微波肿瘤治疗仪的改进,属于医疗设备技术领域。 The present invention relates to a treatment device, in particular an improved cancer treatment to a microwave instrument, a medical technical field devices. 背景技术 Background technique

恶性肺瘤是威胁人类健康和导致死亡的主要原因之一。 Malignant lung tumor is a threat to human health and one of the leading causes of death. 近年来, 微创治疗肿瘤因具有创伤小、并发症低、病人痛苦少等特点,而得到广泛关注。 In recent years, minimally invasive treatment of tumors due with less trauma and complications is low, less patient pain and so on, and received extensive attention. 这种治疗方法与传统的热疗、放疗等方法相比,可以对肿瘤瘤体直接产生摧毁作用,更易达到类似外科手术的根治效果。 This method of treatment as compared with conventional hyperthermia, radiation or the like, can be produced directly destroy tumor effect on tumor easier to achieve a similar effect of radical surgery.

目前,肿瘤微创治疗设备主要有射频、微波、氩氦刀、超声聚焦 Currently, cancer therapy equipment are minimally invasive RF, microwave, cryoablation, focused ultrasound

刀等。 Knives. 其治疗机理都是在B超、CT或MRI引导下,把能量聚集在肿瘤瘤体,用热凝或冷冻的方法使肿瘤组织变性、坏死。 Which are in the B-therapeutic mechanism, under CT or MRI guidance, the energy gathered in the tumor the tumor, the tumor tissue degeneration method using thermosetting or frozen necrosis.

其中,射频集束针在手术过程中存在穿刺不方便、损伤大等缺点。 Wherein the presence of the radio frequency needle puncture bundling inconvenient, injury and other shortcomings in the procedure. 氩氦刀、超声聚焦刀除了存在不能穿过骨骼治疗的缺陷外,均价格昂贵,难以在临床得到广泛应用。 Cryoablation, except that focused ultrasound through the bone defect treated outside, are expensive, difficult to use widely used in clinical. 相对而言,冷循环」微波刀安全性高, 复发率低,病人负担轻,因此具有较好的推广应用前景。 In contrast, the cold cycle "microwave safe knife, recurrence rate, patient burden light, so it has good application prospects.

据申请人了解,现有微波肺瘤治疗仪主要由主机、含微波发生器件的穿刺针(又称微波刀)以及测温装置等构成,主机主要由控制电路、电源电路和键盘/显示板电路构成。 It is understood Applicants, lung tumor prior microwave treatment instrument mainly by the host, the device comprising a microwave puncture needle (also known as microwave coagulation) occurs and the temperature measuring device and the like constituted mainly by a main control circuit, a power circuit and a keyboard / display circuit board constitution. 控制电路中含有微处理芯片以及电压调控电路,安置在病灶上作为测温装置的热电偶的信号输出端经A/D转换器件接微处理芯片的输入端,微处理芯片的控制输出端经电压调控电5^接穿刺针的微波发生器件。 The control circuit contains a microprocessor chip and a voltage regulation circuit, disposed on the lesion as thermocouple temperature measuring signal output means via the A / D conversion device connected to an input terminal of the microprocessor chip, control output voltage by microchips regulation ^ 5 is electrically connected to the puncture needle microwave devices occurs.

临床医疗实践表明,用热电偶作为测温器件,将温度信号通过A/D转换送入^:处理(89c51)芯片,不仅准确度4交差,抗干扰能力 Clinical practice has shown that as a thermocouple temperature measuring device, the temperature signal through A / D conversion into ^: Processing (89C51) chip, not only the accuracy of the cross 4, anti-interference ability

4弱,难以满足微波治疗仪要求精确掌控温度的应用需求,而且由于肺瘤病变组织与正常组织联系密切,只监控病灶处的温度,在治疗中无法形成理想的突变温度场,往往难免损伤正常组织,经常发生穿刺针灼伤皮肤等现象,既给病人带来额外的痛苦,又不利于治疗。 4 weak, can not meet the application requirements of microwave apparatus requires precise control of temperature, and because of lung tumor tissue and normal tissue lesions closely linked, only monitor the temperature of the lesions, can not form the desired changes in temperature in the treatment field, it is often hard to avoid damage to normal organization, often needle to burn the skin and other phenomena occur, not only bring additional suffering to the patient, the treatment does not help. 发明内容 SUMMARY

本发明的目的是:针对以上现有技术存在的缺点,提出一种可以精确控制温度的冷循环微波肿瘤治疗仪,从而既保证热凝胂瘤组织, 又避免灼伤皮肤等正常组织,以期达到最佳的治疗效果。 Object of the present invention is: for the above shortcomings of the prior art, the temperature can be precisely controlled to provide a refrigerating cycle of microwave Tumor Treatment, thereby both to ensure thermosetting arsine tumor tissue, such as skin burns and avoid normal tissues, in order to achieve the most good effect of treatment.

为了达到以上目的,本发明的冷循环微波肿瘤治疗仪由主机、含微波发生电路的穿刺针(又称微波刀)、接穿刺针进液口的冷却系统、 以及测温装置构成;所述主机主要由控制电路、电源电路和键盘/显示板电路构成,所述控制电路中含有微处理芯片;所述微波发生电路含有电压调控电路;所述测温装置至少含有二只独立分布的热敏电阻,其中之一用于安置在病灶附近,另一安置在穿刺针的针杆上;所述冷却系统含有流量控制器件;所述热敏电阻的信号输出端分别接微处理芯片的对应输入端,所述微处理芯片的第一控制输出端接所述穿刺针的微波发生电路的电压调控电路,第二控制输出端接冷却系统的流量控制器件。 To achieve the above object, a refrigerating cycle apparatus according to the present invention, the microwave treatment of tumors by the host, including the puncture needle microwave circuit (also known as microwave coagulation) occurs, then the cooling system of the liquid inlet needle, and a temperature measuring device configured; the host mainly by the control circuit, the power supply circuit and a keyboard / display panel circuit, said control circuit comprising microprocessor chip; said microwave generating circuit comprising a voltage regulation circuit; said temperature measuring means comprises at least two separate thermistor distribution , one of which is disposed in the vicinity of a lesion, placed at the other puncture needle of the needle bar; the cooling system comprises flow control means; the thermistor signal output terminal respectively connected to the corresponding input of the microprocessor chip, circuit voltage regulation circuit, a first control output of the microprocessor chip termination of the puncture needle microwave generator, the control flow of the second output end of the cooling system control means.

采用本发明的冷循环^b皮胂瘤治疗仪后,不^f义测温精度大大提高,抗干扰能力强,而且可以监控病灶与皮肤处的温度,通过分别对输出电压与冷却液流量的准确控制,形成理想的温度场,增加冷循环功能,有效的降低了穿刺针的杆温,在热凝肿瘤组织的同时,可靠避免灼伤皮肤等正常组织,从而达到最佳的治疗效果。 With the present invention, the refrigeration cycle ^ b arsine skin tumor treatment, no ^ f sense temperature measurement accuracy greatly improved anti-jamming capability, but also to monitor the temperature of the skin at the lesion, respectively, by the output voltage of the coolant flow accurate control over the temperature field is formed, to increase circulation of cold, effectively reducing the temperature of the puncture needle bar, while thermal coagulation of tumor tissue, such as skin burns reliably avoid normal tissue, so as to achieve the optimal therapeutic effect. 附图说明 BRIEF DESCRIPTION

下面结合附图对本发明作进一步的说明。 DRAWINGS The invention will be further described below in connection.

5图l是本发明一个实施例的整体框图图。 L FIG. 5 is a general block diagram view of an embodiment of the present invention.

图2是图1实施例中控制电路的电路原理图。 FIG 2 is a schematic circuit diagram of a control circuit in the embodiment of FIG.

图3是图1实施例含有调压电路的微波发生电路原理图。 FIG 3 is a schematic circuit diagram of the microwave embodiment of Figure 1 containing the voltage regulator circuit occurs.

图4是图1实施例的显示电路原理图。 FIG 4 is a schematic circuit diagram shows the embodiment of FIG. 1.

图5是图1实施例的穿刺针结构示意图。 FIG 5 is a schematic block diagram of the puncture needle 1 of the embodiment. 具体实施方式实施例一 DETAILED DESCRIPTION Example embodiments a

本实施例的微波治疗仪如图1所示,由主机、穿刺针、冷却系统、 以及测温装置构成。 Microwave apparatus of the present embodiment shown in Figure 1, is constituted by the host, the puncture needle, a cooling system, and a temperature measuring device. 主机通过同轴电缆接含樣"皮发生器件的穿刺针, 冷却系统接穿刺针的进液口和出液口,形成冷却循环,测温装置以热敏电阻作为传感探头,分别安置在病灶肿瘤组织和穿刺针上。 Host access via a coaxial cable like containing "skin puncture needle device occurs, then the cooling system of the needle inlet and a liquid outlet, a cooling cycle, the temperature measuring means as a thermistor sensing probes, respectively disposed at the lesion tumor tissue and on the puncture needle.

主机主要由控制电路、电源电路和键盘/显示板电路构成。 Host mainly by the control circuit, the power supply circuit and a keyboard / display circuit board. 其中, 控制电路如图2所示,含有两片并接的89C4051微处理芯片U1和U9。 Wherein the control circuit shown in Figure 2, and comprising two contact 89C4051 microprocessor chip U1 and U9. 测温装置采用测量范围在-50°C ~150°C、精度在土O. r'CNTC的热敏电阻作为测温元件,分别安置在病灶和针杆上,此二只独立分布热敏电阻之一输出的测温信号通过接插口JP3的1脚输入,经放大器U5 的2脚输入、6脚输出,被放大后由TLC25431模数转换芯片U2的6 脚输入;另一热敏电阻输出的测温信号经接插口JP3的7脚输入到TLC25431才莫数转换芯片U2的7脚。 Using the temperature measuring device measuring range -50 ° C ~ 150 ° C, accuracy of the thermistor as the temperature measuring O. r'CNTC earth elements, respectively disposed at the needle bar and the lesion, the distribution of two separate thermistor one of the output temperature signal input pin 1 of jack JP3 by contact, via the input amplifier U5, pin 2, the output pin 6, after being amplified by TLC25431 D conversion chip U2 pin 6 input; another thermistor output temperature signals JP3 pin modular jack 7 is input to pin 7 TLC25431 just Mo conversion chip U2. 此两测温信号经112模数转换后, 从16、 18脚输出,分别输入到微处理芯片Ul的17脚和U9的14脚, 并分别由其7脚和8脚将控制信号以低电平经二极管D7、 D8输出到接插口JP1的4脚和5脚。 This two temperature signal 112 after analog-digital conversion, from 16, 18-pin output, pin 17 are input to the Ul microprocessor chip 14 and the foot U9, respectively, 8 feet by 7 feet and the control signal to low level via the diode D7, D8 connected to the output jack JP1 5 feet and 4 feet. 由JP1将此两控制信号分别输出到穿刺针的微波发生调压电路(参见图3)和冷却系统的流量控制器件。 This output from the two control signals JP1 puncture needle to the microwave generator voltage regulator circuit (see FIG. 3) and the flow control means the cooling system.

图2中的两微处理芯片Ul和U9的显示输出口11、 13、 14、 15 脚经接插口JP2外接显示电路(参见图4 ),从而可以实现监测温度、输出功率等参数的显示输出。 Two microprocessor chip Ul in FIG. 2 and the display output U9 11, 13, 14, 15 feet by modular jack JP2 external display circuit (see FIG. 4), thereby displaying output parameters to monitor temperature, output power can be realized.

此外,图2中还含有如下辅助电路: Further, in FIG. 2 as an auxiliary circuit further comprises:

1、 电源电路——由图2左上角的D1、 U7、 U8整流稳压电路构成,向各器件提供电源。 1, a power supply circuit -, U7, U8 rectifier regulator circuit is constituted by the upper left corner D1 of FIG 2, provides the power to each device.

2、 运放电路——由图1右上角的2904四运放芯片U6构成。 2, the operational amplifier circuit - composed of a quad op amp 2904 in FIG chip U6 1 the upper right corner. 模数转换芯片U2的运放输出端5脚分别经阻容器件与运放芯片U6的输入端3脚和5脚连接,U6芯片的输出端1脚和7脚分别回接模数转换芯片U2的5脚和6脚。 D conversion chip U2 op amp output 5 feet were 3 feet and 5 pin connector via the input resistance of the container member and the op-amp chip U6 end, U6 chip output of 1 foot and 7 feet respectively tieback D conversion chip U2 5 feet and 6 feet. 这样,可以提高信号精度,有利于精确控制温度。 In this way, improved signal accuracy, facilitate precise temperature control.

3、 反倍压电路——主要由图1右下角的7660反倍压芯片U4构成, 其作用是提供负电压给U5和UIO芯片。 3, anti-doubling circuit - 7660 consists essentially of trans FIG voltage doubler chip U4 1 the lower right corner, its role is to provide a negative voltage to the chip U5 and UIO. 由电路提供的正电压信号进入到U4后,经过;故大反向,输出到U5和U10的第4脚,供应其负电压信号。 After the positive voltage signal supplied by the circuit into U4, via; reverse so large, the output of U5 and U10 pin 4, the negative supply voltage signal.

4、 稳压基准电路——由U4右侧的三极管TL431极其周围的可调电位计以及电容器件组合而成,通过调节可调电位计可以调整供应电压, 并使电压稳定的输出。 4, the regulator reference circuit - extremely around adjustable potentiometer and a capacitor element composition by transistors TL431 U4 from the right, the supply voltage potentiometer can be adjusted, and by adjusting the output voltage stabilization adjustable.

5、 看门狗电路——由Ul左下方的X5045存储芯片U3构成,用于锁定存储。 5, the watchdog circuit - composed of the lower left U3 Ul X5045 memory chip for storing the lock.

微波发生电路如图3所示,左上角的电源经过变压器T3的原边与该变压器副边的-兹控管Ml耦合。 Ml is coupled hereby Controls - upper left corner of the original power supply 3 through the transformer T3 of the transformer secondary side of the microwave generating circuit shown in FIG. 右上角来自控制电路的调压控制信号由接插口J5、 J6接入电压调控电路,经过光电耦合器U2接可控硅U1的控制极,所述可控硅的输出由接插口接变压器T3的原边,从而根据微处理芯片输出的控制信号调节磁控管M1输出到天线J7的微波发射电压,达到控制病灶处温度的目的。 Upper right corner of the regulator control signal from the control circuit by a connector located J5, J6 connection voltage regulation circuit, U2 connected via optocoupler U1 SCR control electrode of the SCR is connected from the output transformer T3 connection socket primary, thereby outputting the signal processing micro-control chip M1 outputs the magnetron is adjusted in accordance with the voltage to the microwave transmitting antenna J7, to control the temperature of the object at the focus.

图4中的显示电路中的数码管经显示驱动芯片由接插口接微处理芯片的显示输出口,与现有技术相同,故不详述。 FIG display circuit 4 through the digital display driver chip connected to the microprocessor by a connector located display output chip is the same as the prior art, it is not described in detail. 针的针尖内装有微波天线4,该微波天线的后端连有同轴电缆9。 The needle tip has a built-in microwave antenna 4, the rear end of the microwave antenna coaxial cable 9 is connected. 针杆内制有环状空腔7。 7 is formed with an annular cavity within the shank. 针把上的进液口外接冷却循环泵,出液口与空腔7连通,外接排液管。 The needle inlet opening communicating an external cooling circulation pump, the liquid outlet cavity 7, an external drain pipe. 在针杆内微波天线4周围的环状空腔7内固定有与进液口连通的毛细管8。 Needle bar in the annular cavity 4 around the microwave antenna 7 is fixed to the capillary tube 8 communicating with the liquid inlet. 作为测温探头的热敏电阻10固定在4十杆内环状空腔7的前端,该测温:寐头的信号输出端经安置在同轴电缆9内的信号线连接到图2的接插口JP3, 测量温度的精度可达到± 0. rc。 As the thermistor temperature probe 10 is fixed within the distal end 4 ten annular cavity 7, which temperature: signal output by the sleep soundly head disposed in the signal line 9 is connected to the coaxial cable of FIG. 2 socket JP3, temperature measurement accuracy can reach ± ​​0. rc.

工作时,具体测温控温过程如下:位于病灶和针杆上的两测温热敏电阻线接接插口JP3的1、 2两头,由于热敏电阻具有随温度升高电阻变小的特性,因此加在两端的电压会随着温度的增加而降低。 In operation, temperature measurement and control specific process is as follows: the needle bar is located in the lesion and two temperature measuring thermistor wire to connector JP3 contact 1, 2 two, since the thermistor has a characteristic with increasing temperature the resistance becomes smaller, Thus the voltage applied across decreases with increasing temperature. 测温电压信号经电阻进入OP07信号放大芯片U5的2、 3脚,经过放大后由第6脚输出。 Temperature into the voltage signal by the resistor 2, pin 3 OP07 chip U5 is amplified signal, after amplification by the output pin 6. 而后进入到TLC2543I芯片U2的5、 6脚进行A/D 转换,再接到主控制微处理芯片Ul或U9的89C4051芯片的17脚。 Then proceeds to 5, TLC2543I chip U2 pin 6 performs A / D conversion, and then to the main control chip Ul microprocessor 17 or the foot 89C4051 chip U9.

经此数据传输,测温数据进入到主程序,经过程序对数据的分析后,输出到显示电路,从而显示出测温探头所测量的温度值。 After this data transfer, the main routine proceeds to temperature data, after the data analysis program, output to the display circuit, thereby displaying the temperature value of the measured temperature probe. 同时微处理芯片比较测量温度与预设温度,并根据比较结果输出相应的控制信号,控制穿刺针的微波发射电压,调节病灶处的温度;并控制接冷却系统的泵流量,调节穿刺针对皮肤等正常组织的温度。 Microprocessor chip while comparing the measured temperature with a preset temperature, according to the comparison result and outputs a corresponding control signal to control the microwave emitter voltage puncture needle, adjusting the temperature of the lesions; and controlling the flow rate of a pump connected to the cooling system, skin and the like for adjusting the lancing temperature is normal tissues.

由于采用了敏感的热敏电阻,并分别由两组微处理芯片对病灶和 As a result of the sensitive thermistor, respectively by two microprocessor chip and lesions

正常组织的温度进行合理控制,因此测温精度高达土o. rc,可以形 Reasonable temperature control normal tissue, thus high temperature measurement accuracy Soil o. Rc, can be formed

成正常组织到肿瘤組织的突变温度场,从而获得最佳治疗效果。 To the normal tissue to tumor tissue mutations temperature field, so as to obtain the optimal therapeutic effect. 临床治疗证明,本实施例的微波治疗仪具有以下优点: 1、除灭活作用外,还有抑制效果——在B超、CT、 MRI或X光引导下,把穿刺针(又称微波刀)^肿瘤瘤体后,可以使其中的极性分子在微波场的作用下高速运动磨擦产生热量,由于温度控制准 Clinical proof, embodiment of the microwave apparatus of the present embodiment has the following advantages: 1, in addition to inactivation, as well as inhibitory effect - in the B, CT, MRI or X-ray guidance, the needle (also known as microwave knife ) ^ tumor after tumor, wherein the polar molecules can make high-speed movement under the effect of friction heat generated in the microwave field, because the temperature control registration

8确,因此不仅可以使肿瘤细胞的蛋白质变性凝固,逆坏死,而且灭活的肿瘤组织可生产热休克蛋白,刺激机体的免疫系统,提高机体的免 8 indeed, it is possible to not only tumor cells denature proteins coagulation, reverse necrosis, and inactivation of tumor tissue can produce heat shock proteins, stimulate the immune system, enhance the body's Free

疫功能,起到抑制肿瘤细胞扩散的作用。 Immune function, play a role in inhibiting tumor cell proliferation.

2、 消融范围大——由于对冷却系统的有效控制,不必担心正常 2, ablation large range - due to the effective control of the cooling system, normally do not worry

组织受损,因此可以充分发棒敞波效能,使肿瘤凝固治疗更快,灭活 Tissue damage, the rod can be made sufficiently open wave performance, faster coagulation therapy of the tumor, inactivated

范围更大,可原位灭活5cm直径的肿瘤。 Larger, in situ inactivation of 5cm diameter of the tumor.

3、 术中病人负担轻一一传统微波穿刺针的高杆温刺激肝包膜等组织,术中病人疼痛感强,常迫使手术停顿,有时不得不以全麻来解决,而本实施例可以确保穿刺针的杆温不超过体温,术中病人负担轻、 痛苦少,不会烫伤皮肤。 3, intraoperative patient lighten the burden of eleven traditional microwave needle bar high temperatures stimulate the liver capsule and other organizations, strong pain patient surgery, surgery often forced pause, sometimes general anesthesia had to be solved, but the present embodiment can ensure that the needle bar temperature does not exceed body temperature, lighten the burden of surgery patients, less pain, do not burn the skin.

4 、安全性高——高精度测温系统可在不切断微波输出的状态下实现同步探测和控制肿瘤核心的边缘温度,得到确实的灭活数据,测 4, high security - with high accuracy temperature measurement system can realize edge detection and synchronization control temperature in the core of the tumor without cutting the microwave output data obtained does inactivation measured

温精度高达土o.rc,安全保护功能强,可靠性高,针道创伤小,出血少,愈合快。 Temperature accuracy up soil o.rc, security features, high reliability, the needle tract trauma, less bleeding, faster healing.

5、使用范围广一一不仅可用于肝癌,也可用于肺癌,乳腺癌、 5, using a wide range of eleven not only for liver cancer, can also be used for lung cancer, breast cancer,

胰腺癌、前列腺癌、骨癌、子宫肌瘤等实体瘤的治疗。 Treatment of solid tumors of pancreatic cancer, prostate cancer, bone cancer, uterine fibroids.

除上述实施例外,本发明还可以有其他实施方式。 In addition to the above-described embodiment exceptions, the present invention is capable of other embodiments. 例如,冷却系 For example, the cooling system

统的流量控制器件可以是驱动冷却泵的调速电机,也可以是冷却管路 Conventional flow-control devices can be driven cooling pump motor speed, the cooling circuit may be

中的流量控制阀等等, The flow control valve and the like,

凡采用等同替换或等效变换形成的技术方案,均落在本发明要求 Where the use of equivalent replacement or equivalent transformation formed aspect, the present invention all fall in claim

的保护范围。 The scope of protection.

9 9

Claims (8)

1. 一种冷循环微波肿瘤治疗仪,由主机、含微波发生电路的穿刺针、接穿刺针进液口的冷却系统、以及测温装置构成;所述主机主要由控制电路、电源电路和键盘/显示板电路构成,所述控制电路中含有微处理芯片;所述微波发生电路含有电压调控电路;其特征在于:所述测温装置至少含有二只独立分布的热敏电阻,其中之一用于安置在病灶附近,另一安置在穿刺针的针杆上;所述冷却系统含有流量控制器件;所述热敏电阻的信号输出端分别接微处理芯片的对应输入端,所述微处理芯片的第一控制输出端接所述穿刺针的微波发生电路的电压调控电路,第二控制输出端接冷却系统的流量控制器件。 A microwave Cool Tumor Treatment, by the host, the puncture needle containing a microwave generating circuit, connected to the cooling system of the liquid inlet needle, and a temperature measuring device configured; the host mainly by the control circuit, the power supply circuit and a keyboard / display panel circuit, said control circuit comprising microprocessor chip; said microwave generating circuit comprising a voltage regulation circuit; characterized in that: said temperature measuring means comprises at least two thermistor independently distributed, with one of disposed in the vicinity of the lesion in the other needle shaft disposed in the puncture needle; the cooling system comprising a flow control device; and a signal output of the thermistor corresponding to input terminals respectively connected to the microprocessor chip, said microprocessor chip circuit voltage regulation circuit controlling the output end of said first puncture needle microwave generator, the control flow of the second output end of the cooling system control means.
2. 根据权利要求1所述冷循环微波肿瘤治疗仪,其特征在于: 还含有由运放芯片构成的运放电路,所述热敏电阻的信号输出经模数转换芯片接微处理芯片的对应输入端,所述模数转换芯片的运放输出端经阻容器件与运放芯片的输入端连接,所述运放芯片的输出端回接模数转换芯片。 1 according to the refrigeration cycle apparatus as claimed in claim Microwave tumor therapy, wherein: the operational amplifier circuit further comprises operational amplifier chip made of a corresponding signal output by the analog-digital conversion of the thermistor chip bonding microchips input, the analog to digital converter chip through the output terminal of the operational amplifier and the input of the container member resistor operational amplifier chip is connected, an output terminal of the operational amplifier chip tieback D conversion chip.
3. 根据权利要求1所述冷循环微波肝瘤治疗仪,其特征在于: 所述控制电路含有两片并接的微处理芯片,其输入端分别接用于安置在病灶附近和安置在穿刺针的针杆上的热敏电阻;所述输入端接安置在病灶附近热敏电阻的微处理芯片的控制输出端作为第一控制输出端,接所述穿刺针的微波发生电路的电压调控电路;所述输入端接安制输出端,接冷却系统的流量控制器件。 3. The refrigeration cycle as claimed in claim 1 hepatoma microwave therapeutic apparatus, wherein: said control circuit comprising two microchips and contact, respectively connected to an input terminal disposed in the vicinity of the lesion and disposed in the puncture needle thermistor needle rod; the control input terminal of the output end disposed in the vicinity of the microprocessor chip thermistor lesions as the first control output of the voltage regulation circuit connected to the circuit of the puncture needle microwave generator; An input terminal of the system output, the flow control means connected to the cooling system.
4. 根据权利要求2或3所述冷循环微波肿瘤治疗仪,其特征在于:所迷微波发'生电路的电源经过变压器的原边与该变压器副边的磁控管耦合,来自控制电路的调压控制信号经过光电耦合器接电压调控电路中可控硅的控制极,所述可控硅的输出由接所述变压器的原边。 The refrigeration cycle 2 or 3 Tumor Treatment Microwave claims, characterized in that: the fans microwave sent 'through the magnetron power supply generating circuit coupled to the primary side of the transformer secondary side of the transformer, from the control circuit voltage control signal through the optocoupler to the control voltage regulation circuit thyristor pole, said thyristor connected to the output of the primary side of the transformer.
5. 根据权利要求4所述冷循环微波肺瘤治疗仪,其特征在于: 所述穿剌针的针尖内装有微波天线,所述微波天线的后端连有同轴电缆。 The refrigeration cycle of the 4 lung tumor microwave therapeutic apparatus as claimed in claim, characterized in that: said puncture needle tip of a microwave antenna that has the rear end of the microwave antenna connected coaxial cable.
6. 根据权利要求5所述冷循环微波肿瘤治疗仪,其特征在于: 所述穿刺针的针杆内制有环状空腔,针把上的进液口外接冷却循环泵,出液口与所述空腔连通,外接排液管。 5 according to the refrigeration cycle apparatus as claimed in claim microwave treatment of tumors, characterized in that: said cavity is formed with an annular inner needle puncture needle bar, a needle to an external cooling liquid inlet of the circulation pump, and a liquid outlet communicating said cavity, an external drain pipe.
7. 根据权利要求6所述冷循环微波肿瘤治疗仪,其特征在于: 所述穿刺针的针杆内的环状空腔固定有与进液口连通的毛细管,作为测温探头的热敏电阻固定在针杆内环状空腔的前端。 7. Cool the microwave 6 Tumor Treatment according to claim, characterized in that: said annular cavity within the needle puncture needle bar is fixed to the capillary tube in communication with the liquid inlet, a thermistor temperature probe fixing the distal end of the annular cavity in the needle bar.
8. 根据权利要求7所述冷循环微波肿瘤治疗仪,其特征在于: 所述测温探头的信号输出端经安置在同轴电缆内的信号线连接J'j微处理芯片。 According to claim 7 Cool microwave Tumor Treatment, characterized in that: said temperature signal output terminal via probe disposed in the signal line of the coaxial cable J'j microprocessor chip.
CN 200610085783 2006-06-30 2006-06-30 Cold circulation microwave tumor therapeutic apparatus CN100518684C (en)

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CN104224434B (en) * 2010-11-10 2016-09-14 余丽 Precise temperature control for Tumor Treatment
CN101972188A (en) * 2010-11-10 2011-02-16 韩俊江;琚力强 Precise temperature-controlling tumor therapeutic apparatus and control method thereof
CN102551873A (en) * 2010-12-10 2012-07-11 韩俊峰 Accurate temperature control tumor therapeutic apparatus and control method thereof
CN106037929A (en) * 2016-05-23 2016-10-26 方崇亮 Thyroid nodule and tumor color Doppler imaging microwave treatment system and needle selection method
WO2019041217A1 (en) * 2017-08-31 2019-03-07 Covidien Lp Systems and methods for sensing temperature at different locations on a microwave antenna using multiple fiber sensors

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