CN102743536A - Traditional Chinese medicine granula for preventing and treating rabbit coccidiosis and preparation method thereof - Google Patents
Traditional Chinese medicine granula for preventing and treating rabbit coccidiosis and preparation method thereof Download PDFInfo
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- CN102743536A CN102743536A CN2012102664065A CN201210266406A CN102743536A CN 102743536 A CN102743536 A CN 102743536A CN 2012102664065 A CN2012102664065 A CN 2012102664065A CN 201210266406 A CN201210266406 A CN 201210266406A CN 102743536 A CN102743536 A CN 102743536A
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Abstract
The invention provides a traditional Chinese medicine granula for preventing and treating rabbit coccidiosis and a preparation method thereof. The traditional Chinese medicine granula is composed of raw materials by weight, 2-5 parts of cortex meliae, 1-4 parts of fruits of rangoon creeper, 1-2 parts of betel nuts and 1-2 parts of rheum officinale. The traditional Chinese medicine granula is prepared by adding cane sugar after decoction. The traditional Chinese medicine granula for preventing and treating the rabbit coccidiosis reasonably organizes traditional Chinese medicines, has effects of desinsectization and removing pattogenic heat from the blood and toxic material from the body, provides an effective therapeutic drug for the rabbit coccidiosis, and has advantages of being rapid in effect, real in curative effect, free of medicine residual and free of any toxic and side effects. In addition, the preparation method of the traditional Chinese medicine granula is simple and suitable to needs of large-scale industrial production.
Description
Technical field
The present invention relates to a kind of Chinese medicine granules and preparation method thereof, especially a kind of Chinese medicine granules of preventing and treating rabbit coccidiosis and preparation method thereof.
Background technology
Rabbit coccidiosis is that rabbit is the most common and endanger serious a kind of protozoacide, and the rabbit infection rate in the 4-5 monthly age can reach 100%, and mortality rate reaches 70%, and the rabbit growth promoter of anti-mistake is had a strong impact on, loss of weight 12%-27%.This disease clinical manifestation is loss of appetite or gives up and cut off that spirit is depressed, backwardness, and it is motionless to lie prostrate, the pale or xanthochromia of eye conjunctiva, diarrhoea or constipation, the tabletting microscopy is it is thus clear that there are a large amount of egg capsules.Therefore utilize the natural resources of Chinese medicinal materials of China's abundant,, be used to treat rabbit coccidiosis and will have very important production practices meaning through Chinese medicine is rationally screened and prescription.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine granules of preventing and treating rabbit coccidiosis.
Another technical problem to be solved by this invention is to provide the method for preparing of the Chinese medicine granules of above-mentioned control rabbit coccidiosis.
For solving the problems of the technologies described above, technical scheme of the present invention is:
A kind of Chinese medicine granules of preventing and treating rabbit coccidiosis is made up of Cortex Meliae, Fructus Quisqualis, Semen Arecae and Radix Et Rhizoma Rhei, by its parts by weight Cortex Meliae 2-5 part, Fructus Quisqualis 1-4 part, Semen Arecae 1-2 part, Radix Et Rhizoma Rhei 1-2 part.
Preferably, the Chinese medicine granules of above-mentioned control rabbit coccidiosis is by its parts by weight Cortex Meliae 3-4 part, Fructus Quisqualis 2-3 part, Semen Arecae 1-2 part, Radix Et Rhizoma Rhei 1-1.5 part.
Preferably, the Chinese medicine granules of above-mentioned control rabbit coccidiosis, by 3 parts of its parts by weight Cortex Meliaees, 3 parts of Fructus Quisqualis, 1 part of Semen Arecae, 1 part of Radix Et Rhizoma Rhei.
The method for preparing of the Chinese medicine granules of above-mentioned control rabbit coccidiosis, concrete preparation process is following:
(1) taking by weighing Cortex Meliae 2-5 part, Fructus Quisqualis 1-4 part, Semen Arecae 1-2 part, Radix Et Rhizoma Rhei 1-2 part by weight is raw material;
(2) water of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time; Decocted 1.5 hours for the second time, collecting decoction filters; Filtrating was left standstill 24 hours, got under 1.28,80 ℃ of conditions of supernatant concentration to relative density and obtained concentrated extract;
(3) step (2) gained concentrated extract is dried the back under 60-70 ℃ of condition and pulverize, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, process granule and cross 10 mesh sieves with 85% (v/v) ethanol, 60 ℃ of oven dry promptly get after 10 mesh sieves.
Preferably, extract powder and sucrose are by 1 part of its parts by weight extract powder, sucrose 2-7 part in the method for preparing of the Chinese medicine granules of above-mentioned control rabbit coccidiosis, said step (3).
Preferably, extract powder and sucrose are by 1 part of its parts by weight extract powder, 2 parts of sucrose in the method for preparing of the Chinese medicine granules of above-mentioned control rabbit coccidiosis, said step (3).
Above-mentioned relative density is meant the proportion of this supernatant.
The consumption of the Chinese medicine granules of above-mentioned control rabbit coccidiosis lets rabbit freely drink in drinking-water the Chinese medicine granules mixing for the ratio in the said Chinese medicine granules of 5g in every 1000kg water, and logotype 3～5 days was a course of treatment.
The invention has the beneficial effects as follows:
The Chinese medicine granules of above-mentioned control rabbit coccidiosis; With the Chinese medicine reasonable formula; Effect with anthelmintic, removing pathogenic heat from blood and toxic substance from the body, for rabbit keeping provides a kind of effective medicine of rabbit coccidiosis, have instant effect, curative effect really, no drug residue, characteristics without any side effects; Its preparation method is simple, is fit to requirements of large-scale industrial production.
The specific embodiment
Below in conjunction with specific embodiment technical scheme according to the invention is further described.
Embodiment 1
A kind of Chinese medicine granules of preventing and treating rabbit coccidiosis is made up of Cortex Meliae, Fructus Quisqualis, Semen Arecae and Radix Et Rhizoma Rhei, wherein Cortex Meliae 3kg, Fructus Quisqualis 3kg, Semen Arecae 1kg, Radix Et Rhizoma Rhei 1kg.
The method for preparing of the Chinese medicine granules of above-mentioned control rabbit coccidiosis, concrete preparation process is following:
(1) taking by weighing Cortex Meliae 3kg, Fructus Quisqualis 3kg, Semen Arecae 1kg, Radix Et Rhizoma Rhei 1kg is raw material;
(2) water of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time; Decocted 1.5 hours for the second time, collecting decoction filters; Filtrating was left standstill 24 hours, got under 1.28,80 ℃ of conditions of supernatant concentration to relative density and obtained concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 67 ℃ of conditions pulverizes; Obtain extract powder; In this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are processed granule and are crossed 10 mesh sieves with 85% (v/v) ethanol by 1 part of its parts by weight extract powder, 2 parts of sucrose; 60 ℃ of oven dry promptly get after 10 mesh sieves.
Embodiment 2
A kind of Chinese medicine granules of preventing and treating rabbit coccidiosis is made up of Cortex Meliae, Fructus Quisqualis, Semen Arecae and Radix Et Rhizoma Rhei, wherein Cortex Meliae 2kg, Fructus Quisqualis 4kg, Semen Arecae 2kg, Radix Et Rhizoma Rhei 1kg.
The method for preparing of the Chinese medicine granules of above-mentioned control rabbit coccidiosis, concrete preparation process is following:
(1) taking by weighing Cortex Meliae 2kg, Fructus Quisqualis 4kg, Semen Arecae 2kg, Radix Et Rhizoma Rhei 1kg is raw material;
(2) water of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time; Decocted 1.5 hours for the second time, collecting decoction filters; Filtrating was left standstill 24 hours, got under 1.28,80 ℃ of conditions of supernatant concentration to relative density and obtained concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 70 ℃ of conditions pulverizes; Obtain extract powder; In this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are processed granule and are crossed 10 mesh sieves with 85% (v/v) ethanol by 1 part of its parts by weight extract powder, 7 parts of sucrose; 60 ℃ of oven dry promptly get after 10 mesh sieves.
Embodiment 3
A kind of Chinese medicine granules of preventing and treating rabbit coccidiosis is made up of Cortex Meliae, Fructus Quisqualis, Semen Arecae and Radix Et Rhizoma Rhei, wherein Cortex Meliae 5kg, Fructus Quisqualis 1kg, Semen Arecae 1kg, Radix Et Rhizoma Rhei 2kg.
The method for preparing of the Chinese medicine granules of above-mentioned control rabbit coccidiosis, concrete preparation process is following:
(1) taking by weighing Cortex Meliae 5kg, Fructus Quisqualis 1kg, Semen Arecae 1kg, Radix Et Rhizoma Rhei 2kg is raw material;
(2) water of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time; Decocted 1.5 hours for the second time, collecting decoction filters; Filtrating was left standstill 24 hours, got under 1.28,80 ℃ of conditions of supernatant concentration to relative density and obtained concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 60 ℃ of conditions pulverizes; Obtain extract powder; In this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are processed granule and are crossed 10 mesh sieves with 85% (v/v) ethanol by 1 part of its parts by weight extract powder, 5 parts of sucrose; 60 ℃ of oven dry promptly get after 10 mesh sieves.
Embodiment 4
A kind of Chinese medicine granules of preventing and treating rabbit coccidiosis is made up of Cortex Meliae, Fructus Quisqualis, Semen Arecae and Radix Et Rhizoma Rhei, wherein Cortex Meliae 3kg, Fructus Quisqualis 3kg, Semen Arecae 2kg, Radix Et Rhizoma Rhei 1kg.
The method for preparing of the Chinese medicine granules of above-mentioned control rabbit coccidiosis, concrete preparation process is following:
(1) taking by weighing Cortex Meliae 3kg, Fructus Quisqualis 3kg, Semen Arecae 2kg, Radix Et Rhizoma Rhei 1kg is raw material;
(2) water of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time; Decocted 1.5 hours for the second time, collecting decoction filters; Filtrating was left standstill 24 hours, got under 1.28,80 ℃ of conditions of supernatant concentration to relative density and obtained concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 65 ℃ of conditions pulverizes; Obtain extract powder; In this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are processed granule and are crossed 10 mesh sieves with 85% (v/v) ethanol by 1 part of its parts by weight extract powder, 3 parts of sucrose; 60 ℃ of oven dry promptly get after 10 mesh sieves.
Embodiment 5
A kind of Chinese medicine granules of preventing and treating rabbit coccidiosis is made up of Cortex Meliae, Fructus Quisqualis, Semen Arecae and Radix Et Rhizoma Rhei, wherein Cortex Meliae 4kg, Fructus Quisqualis 2kg, Semen Arecae 1kg, Radix Et Rhizoma Rhei 1.5kg.
The method for preparing of the Chinese medicine granules of above-mentioned control rabbit coccidiosis, concrete preparation process is following:
(1) taking by weighing Cortex Meliae 4kg, Fructus Quisqualis 2kg, Semen Arecae 1kg, Radix Et Rhizoma Rhei 1.5kg is raw material;
(2) water of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time; Decocted 1.5 hours for the second time, collecting decoction filters; Filtrating was left standstill 24 hours, got under 1.28,80 ℃ of conditions of supernatant concentration to relative density and obtained concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 64 ℃ of conditions pulverizes; Obtain extract powder; In this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are processed granule and are crossed 10 mesh sieves with 85% (v/v) ethanol by 1 part of its parts by weight extract powder, 4 parts of sucrose; 60 ℃ of oven dry promptly get after 10 mesh sieves.
Embodiment 6
A kind of Chinese medicine granules of preventing and treating rabbit coccidiosis is made up of Cortex Meliae, Fructus Quisqualis, Semen Arecae and Radix Et Rhizoma Rhei, wherein Cortex Meliae 3.5kg, Fructus Quisqualis 2.5kg, Semen Arecae 1.5kg, Radix Et Rhizoma Rhei 1kg.
The method for preparing of the Chinese medicine granules of above-mentioned control rabbit coccidiosis, concrete preparation process is following:
(1) taking by weighing Cortex Meliae 3.5kg, Fructus Quisqualis 2.5kg, Semen Arecae 1.5kg, Radix Et Rhizoma Rhei 1kg is raw material;
(2) water of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time; Decocted 1.5 hours for the second time, collecting decoction filters; Filtrating was left standstill 24 hours, got under 1.28,80 ℃ of conditions of supernatant concentration to relative density and obtained concentrated extract;
(3) step (2) gained concentrated extract being dried the back under 62 ℃ of conditions pulverizes; Obtain extract powder; In this extract powder, add sucrose and mix homogeneously, wherein extract powder and sucrose are processed granule and are crossed 10 mesh sieves with 85% (v/v) ethanol by 1 part of its parts by weight extract powder, 2 parts of sucrose; 60 ℃ of oven dry promptly get after 10 mesh sieves.
The said Chinese crude drug of one of embodiment 1-6 is the commercially available prod, and each amounts of components is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
The said Chinese crude drug of embodiment 1-6 all meets " Chinese veterinary drug allusion quotation " version two ministerial standards in 2010.
The composition principle of Chinese medicine oral liquid according to the invention is: Cortex Meliae parasite killing in the side; The Fructus Quisqualis killing insect and eliminating accumulation; The Semen Arecae killing insect and eliminating accumulation, circulation of qi promoting, diuretic cuts cruel; The Radix Et Rhizoma Rhei heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body; All medicines share, and Synergistic is remarkably productive to the control rabbit coccidiosis each other, especially adopts embodiment 1 said proportioning, and the effect of anthelmintic, removing pathogenic heat from blood and toxic substance from the body is very remarkable, particularly is fit to the control of rabbit coccidiosis.
The clinical trial example:
The consumption of the Chinese medicine granules of above-mentioned control rabbit coccidiosis lets laying hen freely drink in drinking-water the Chinese medicine granules mixing for the ratio in the said Chinese medicine granules of 5g in every 1000kg water, and logotype 5 days was a course of treatment.Oral back absorbs the purpose that reaches the treatment disease through gastrointestinal.
In July, 2010, the rabbit invasion in 4200 4 ages at monthly age that the foster rabbit in Tianjin specialist raises, clinical symptoms: loss of appetite or useless exhausted, spirit is depressed; Backwardness, it is motionless to lie prostrate, the pale or xanthochromia of eye conjunctiva; Diarrhoea or constipation, the visible a large amount of egg capsules of tabletting microscopy are diagnosed as coccidiosis.Satisfy with the embodiment of the invention 1 said Chinese medicine granules treatment, medication is after 5 days, and the state of an illness is effectively controlled, week back feed intake increase, and mental restoration is normal, and the excrement inspection does not see that egg capsule is arranged.
Above-mentioned detailed description of this a kind of Chinese medicine granules of preventing and treating rabbit coccidiosis and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (6)
1. a Chinese medicine granules of preventing and treating rabbit coccidiosis is characterized in that: be made up of Cortex Meliae, Fructus Quisqualis, Semen Arecae and Radix Et Rhizoma Rhei, by its parts by weight Cortex Meliae 2-5 part, Fructus Quisqualis 1-4 part, Semen Arecae 1-2 part, Radix Et Rhizoma Rhei 1-2 part.
2. the Chinese medicine granules of control rabbit coccidiosis according to claim 1 is characterized in that: by its parts by weight Cortex Meliae 3-4 part, Fructus Quisqualis 2-3 part, Semen Arecae 1-2 part, Radix Et Rhizoma Rhei 1-1.5 part.
3. the Chinese medicine granules of control rabbit coccidiosis according to claim 1 and 2 is characterized in that: by 3 parts of its parts by weight Cortex Meliaees, and 3 parts of Fructus Quisqualis, 1 part of Semen Arecae, 1 part of Radix Et Rhizoma Rhei.
4. the method for preparing of the Chinese medicine granules of the described control rabbit coccidiosis of one of claim 1-3 is characterized in that: concrete preparation process is following:
(1) taking by weighing Cortex Meliae 2-5 part, Fructus Quisqualis 1-4 part, Semen Arecae 1-2 part, Radix Et Rhizoma Rhei 1-2 part by weight is raw material;
(2) water of 10 times of amounts of adding medical material gross weight in above-mentioned four flavor Chinese medicines decocts 2 times, decocts 2.0 hours for the first time; Decocted 1.5 hours for the second time, collecting decoction filters; Filtrating was left standstill 24 hours, got under 1.28,80 ℃ of conditions of supernatant concentration to relative density and obtained concentrated extract;
(3) step (2) gained concentrated extract is dried the back under 60-70 ℃ of condition and pulverize, obtain extract powder, in this extract powder, add sucrose and mix homogeneously, process granule and cross 10 mesh sieves with 85% (v/v) ethanol, 60 ℃ of oven dry promptly get after 10 mesh sieves.
5. the method for preparing of the Chinese medicine granules of control rabbit coccidiosis according to claim 4 is characterized in that: extract powder and sucrose are by 1 part of its parts by weight extract powder, sucrose 2-7 part in the said step (3).
6. according to the method for preparing of the Chinese medicine granules of claim 4 or 5 described control rabbit coccidiosis, it is characterized in that: extract powder and sucrose are by 1 part of its parts by weight extract powder, 2 parts of sucrose in the said step (3).
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055075A (en) * | 2012-12-04 | 2013-04-24 | 青岛绿曼生物工程有限公司 | Pure Chinese medicinal composition for treating nematodosis and taeniasis of fish and preparation method of pure Chinese medicinal composition |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055075A (en) * | 2012-12-04 | 2013-04-24 | 青岛绿曼生物工程有限公司 | Pure Chinese medicinal composition for treating nematodosis and taeniasis of fish and preparation method of pure Chinese medicinal composition |
| CN103055075B (en) * | 2012-12-04 | 2015-07-29 | 青岛绿曼生物工程有限公司 | Pure Chinese medicine composition for the treatment of fishing line parasitosis and taeniasis and preparation method thereof |
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Application publication date: 20121024 |