CN102727652B - Traditional Chinese medicine composition for enhancing memory as well as preparation method and application of Traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for enhancing memory as well as preparation method and application of Traditional Chinese medicine composition Download PDFInfo
- Publication number
- CN102727652B CN102727652B CN201210248283.2A CN201210248283A CN102727652B CN 102727652 B CN102727652 B CN 102727652B CN 201210248283 A CN201210248283 A CN 201210248283A CN 102727652 B CN102727652 B CN 102727652B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- medicine composition
- radix
- memory reinforcing
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention provides a traditional Chinese medicine composition and aims to achieve the purpose of enhancing the memory by nourishing yin and supplementing kidney, sedating and tranquilizing mind. To achieve the purpose, the technical scheme is adopted as follows: the active ingredients of the traditional Chinese medicine composition are prepared from the following raw materials: codonopsis pilosula, polygala tenuifolia, fructus gleditsiae, poria cocos, spina date seed, angelica sinensis and rehmannia glutinosa; and a corresponding preparation method is adopted as well. The traditional Chinese medicine composition has the effect of enhancing the memory.
Description
Technical field
The present invention relates to Chinese medicine preparation technical field, be specifically related to a kind of Chinese medicine composition for memory reinforcing and method for making and application.
Background technology
For the increase along with the age, the easy hypomnesis of old man, student is because nervous learning life also there will be the situation of hypomnesis, and hypomnesis is multifactorial, as old people's brain aging is degenerated, the multiple situations such as children's's malnutrition.At present, mostly the health food that improves memory on market be by fish oil, and main component is EPA, DHA, lecithin, aminoacid etc.Although health food has certain health-care effect to some aspect of hypomnesis on market, on the whole, ubiquity prevents that the effect of hypomnesis is not remarkable, fills a prescription more single.Existing market is badly in need of a kind of health product that improve hypomnesis.
Summary of the invention
Goal of the invention: in order to address the above problem, the object of the present invention is to provide a kind of Chinese medicine composition that can memory reinforcing.
Another object of the present invention is to provide a kind of preparation method and application of Chinese medicine composition that can memory reinforcing.
Technical scheme: the object of the invention is to realize by following scheme:
A Chinese medicine composition for memory reinforcing, its contained active component is extracted and is prepared from by following raw materials in part by weight medicine proportioning: Radix Codonopsis 10-30 part, Radix Polygalae 5-15 part, Fructus Gleditsiae Abnormalis 10-20 part, Poria 5-15 part, Semen Ziziphi Spinosae 10-20 part, Radix Angelicae Sinensis 10-30 part and Radix Rehmanniae Preparata 10-30 part.
The Chinese medicine composition of above-mentioned memory reinforcing, its contained active component is extracted and to be prepared from by following raw materials in part by weight medicine proportioning: 20 parts, 20 parts of Radix Codonopsis, 10 parts of Radix Polygalaes, 15 parts of Fructus Gleditsiae Abnormalis, 10 parts, Poria, 15 parts of Semen Ziziphi Spinosaes, 20 parts of Radix Angelicae Sinensis and Radix Rehmanniae Preparata.
The Chinese medicine composition of above-mentioned memory reinforcing, described crude drug adds adjuvant after extracting, and with conventional formulation method, makes oral liquid, tablet, capsule or granule.
The Chinese medicine composition of above-mentioned memory reinforcing, described adjuvant is one or more of dextrin, lactose, starch, sucrose, glucose, microcrystalline Cellulose, mannose, methylcellulose, hydroxypropyl cellulose, carboxymethyl cellulose, stevioside.
The method of the Chinese medicine composition of above-mentioned memory reinforcing, preparation process is: get described Radix Codonopsis, Radix Polygalae, Fructus Gleditsiae Abnormalis, Poria, Semen Ziziphi Spinosae, Radix Angelicae Sinensis and Radix Rehmanniae Preparata medical material merge, decoct with water twice, collecting decoction, while being concentrated into 65 ℃, relative density is 1.10-1.20, adding ethanol makes to reach 65-85% containing the percent by volume of alcohol amount, stir, standing, filter, when filtrate decompression is concentrated into 65 ℃, relative density is 1.20-1.30 and reclaims ethanol, obtain concentrated solution, add adjuvant and water is prepared into oral liquid, or concentrated solution spraying is dry, be ground into dry extract, add adjuvant, granulation agent, tablet or capsule.
The preparation method of the Chinese medicine composition of above-mentioned memory reinforcing, decocting condition is: the 8-12 that adds for the first time water and be medical material weight doubly measures, and decocts 1-2h, the 6-10 that adds for the second time water and be medical material weight doubly measures, and decocts 1-2h.
The preparation method of the Chinese medicine composition of above-mentioned memory reinforcing, described spraying drying condition is: inlet temperature is 100-120 ℃, and leaving air temp is 80-90 ℃, and temperature of charge is 70-90 ℃, and atomizing pressure is 0.2-0.4 MPa, spray velocity is 5-10ml/s.
By animal experiment study, find, Chinese medicine composition of the present invention has good memory reinforcing effect.Therefore, the present invention also provides the purposes of aforementioned pharmaceutical compositions, i.e. the application of the Chinese medicine composition of above-mentioned memory reinforcing in preparing memory reinforcing medicine.
Beneficial effect:
1, from theory of Chinese medical science, Radix Codonopsis invigorating the spleen and replenishing QI, enriching blood and promoting secretion of body fluid in we, the Radix Polygalae Fructus Alpiniae Oxyphyllae of calming the nerves, Fructus Gleditsiae Abnormalis eliminates the phlegm and has one's ideas straightened out, Radix Codonopsis, Radix Polygalae and Fructus Gleditsiae Abnormalis are monarch drug, enriching yin and nourishing kidney, mind tranquilizing and the heart calming, Poria spleen invigorating mind calming, inducing diuresis to remove edema, Semen Ziziphi Spinosae nourish heart the liver benefiting, the arresting sweating of calming the nerves, Poria and Semen Ziziphi Spinosae are ministerial drug, strengthen enriching yin and nourishing kidney, the mind tranquilizing and the heart calming effect of monarch drug, Chinese angelica blood supplementing regulating menstruation, the Radix Rehmanniae Preparata yin nourishing of enriching blood, life essence-filling, marrow-benefitting, Radix Angelicae Sinensis and Radix Rehmanniae Preparata are adjuvant, all medicines are harmonious, play altogether enriching yin and nourishing kidney, mind tranquilizing and the heart calming effect, for memory reinforcing.
2, Formulation of the present invention is reasonable, and compatibility is rigorous.
3, the present invention consists of Chinese crude drug, have no side effect, and low price.
The specific embodiment
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as to the scope of the above-mentioned theme of the present invention only limits to following example, all technology realizing based on foregoing of the present invention all belong to scope of the present invention.
1,, in conjunction with the specific embodiment, the present invention is further described as follows:
According to the form below, listed weight proportion takes raw material required for the present invention, unit: part
| Radix Codonopsis | Radix Polygalae | Fructus Gleditsiae Abnormalis | Poria | Semen Ziziphi Spinosae | Radix Angelicae Sinensis | Radix Rehmanniae Preparata | |
| 1 | 10 | 15 | 10 | 15 | 10 | 30 | 10 |
| 2 | 20 | 10 | 15 | 10 | 15 | 20 | 20 |
| 3 | 30 | 5 | 20 | 5 | 20 | 10 | 30 |
In Raw medicine of the present invention Fructus Gleditsiae Abnormalis by leguminous plant Fructus Gleditsia Gleditsia sinensis Lam. old and feeble or be hurt after the fruit tied, all the other all select Chinese Pharmacopoeia kind.
2, Preparation Example
More than showing Raw proportioning is example, comprises the following steps:
The preparation of granule:
Get Radix Codonopsis 30g, Radix Polygalae 5g, Fructus Gleditsiae Abnormalis 20g, Poria 5g, Semen Ziziphi Spinosae 20g, Radix Angelicae Sinensis 10g and Radix Rehmanniae Preparata 30g medical material also mix, decoct with water twice, adding for the first time water is 8 times of amounts of medical material weight, decoct lh, adding for the second time water is 6 times of amounts of medical material weight, decoct 1h, collecting decoction, filter, filtrate is concentrated into relative density 1.10 (65 ℃), adding appropriate ethanol makes to reach 65% containing alcohol amount (volume fraction), stir, standing 24 hours, filter, filtrate recycling ethanol, and be concentrated into the extractum of relative density 1.20 (65 ℃), obtain concentrated solution, it is spray-dried that (condition is that inlet temperature is 100 ℃, leaving air temp is 80 ℃, temperature of charge is 70 ℃, atomizing pressure is 0.2 MPa, spray velocity is 5ml/s.), be ground into dry extract, then add suitable dextrin, with appropriate 80% ethanol moistening, soft material processed, cross 14 mesh sieves and granulate, 50-80 ℃ is dry, and 60 order granulate, obtain granule.
The preparation of tablet:
Get Radix Codonopsis 10g, Radix Polygalae 15g, Fructus Gleditsiae Abnormalis 10g, Poria 15g, Semen Ziziphi Spinosae 10g, Radix Angelicae Sinensis 30g and Radix Rehmanniae Preparata 10g medical material also mix, decoct with water twice, adding for the first time water is 10 times of amounts of medical material weight, decoct 1.5h, adding for the second time water is 8 times of amounts of medical material weight, decoct 1.5h, collecting decoction, filter, filtrate is concentrated into relative density 1.15 (65 ℃), adding appropriate ethanol makes to reach 75% containing alcohol amount (volume fraction), stir, standing 24 hours, filter, filtrate recycling ethanol to be concentrated into relative density be 1.25 (65 ℃), obtain concentrated solution, it is spray-dried that (condition is that inlet temperature is 110 ℃, leaving air temp is 90 ℃, temperature of charge is 80 ℃, atomizing pressure is 0.3 MPa, spray velocity is 7.5/s.), be ground into dry extract, then add appropriate amount of starch, mix homogeneously, with appropriate 80% ethanol moistening, soft material processed, crosses 30 mesh sieves and granulates, in 70～80 ℃ dry, with 60 mesh sieve granulate, tabletting, sugar coating, subpackage, outer package, censorship is qualified, obtains tablet finished product.
The preparation of oral liquid:
Get Radix Codonopsis 20g, Radix Polygalae 10g, Fructus Gleditsiae Abnormalis 15g, Poria 10g, Semen Ziziphi Spinosae 15g, Radix Angelicae Sinensis 20g and Radix Rehmanniae Preparata 20g medical material also mix, decoct with water twice, adding for the first time water is 12 times of amounts of medical material weight, decoct 2h, adding for the second time water is 10 times of amounts of medical material weight, decoct 2h, collecting decoction, filter, filtrate is concentrated into relative density 1.20 (65 ℃), adding appropriate ethanol makes to reach 85% containing alcohol amount (volume fraction), stir, standing 24 hours, filter, filtrate recycling ethanol is also concentrated into relative density 1.30 (65 ℃), obtain concentrated solution, add appropriate sucrose and water, obtain oral liquid finished product.
The preparation of capsule:
Get Radix Codonopsis 20g, Radix Polygalae 10g, Fructus Gleditsiae Abnormalis 15g, Poria 10g, Semen Ziziphi Spinosae 15g, Radix Angelicae Sinensis 20g and Radix Rehmanniae Preparata 20g medical material also mix, decoct with water twice, adding for the first time water is 10 times of amounts of medical material weight, decoct 1.5h, adding for the second time water is 8 times of amounts of medical material weight, decoct 1.5h, collecting decoction, filter, filtrate is concentrated into relative density 1.15 (65 ℃), adding appropriate ethanol makes to reach 75% containing alcohol amount (volume fraction), stir, standing 24 hours, filter, filtrate recycling ethanol is also concentrated into relative density 1.25 (65 ℃), obtain concentrated solution, it is spray-dried that (condition is that inlet temperature is 120 ℃, leaving air temp is 90 ℃, temperature of charge is 90 ℃, atomizing pressure is 0.4 MPa, spray velocity is 7.5/s.), be ground into dry extract, cross sieve No. 6, reinstall capsule No. 1, obtain capsule finished product.
3. the impact experiment on mouse memory power
3.1 laboratory animals: Kunming mouse, male, body weight 18-22g, Shanghai Slac Experimental Animal Co., Ltd. provides.
3.2 Experimental agents: this Chinese medicine composition oral liquid, by above-mentioned oral liquid embodiment method preparation, get Radix Codonopsis 20g, Radix Polygalae 10g, Fructus Gleditsiae Abnormalis 15g, Poria 10g, Semen Ziziphi Spinosae 15g, Radix Angelicae Sinensis 20g and Radix Rehmanniae Preparata 20g medical material also mix, decoct with water twice, adding for the first time water is 12 times of amounts of medical material weight, decoct 2h, adding for the second time water is 10 times of amounts of medical material weight, decoct 2h, collecting decoction, filter, filtrate is concentrated into relative density 1.20 (65 ℃), adding appropriate ethanol makes to reach 85% containing alcohol amount (volume fraction), stir, standing 24 hours, filter, filtrate recycling ethanol is also concentrated into relative density 1.30 (65 ℃), obtain concentrated solution, add appropriate sucrose and water, obtain 10 of oral liquids, specification: 10ml/ props up (being equivalent to containing crude drug 11g), Nanjing University of Traditional Chinese Medicine's self-control, lot number: 20120311, Kang Fu carrys out the light capsule of board brain, authentication code: No. 0136th, hygienic food and health number (2002), manufacturing enterprise: Shuande, Foshan City Kang Fu comes health product company limited, lot number is 20110712, specification: every dress 0.20g.
3.3 dosages: according to the dose,equivalent ratio table > > converting by surface between < < humans and animals, Chinese medicine oral liquid of the present invention, adult's dose is every day three times, 1 of every day, therefore every day, 70 kilograms of people's consumption was 33g, every day, the consumption of every 20g mice was 33*0.0026=0.0858g, because every oral liquid 10ml is 11g containing crude drug amount, the consumption that is every mice is 0.078ml, for ease of administration, low dose of gavage 0.1ml oral liquid, dosage and high dose difference gavage 0.2ml and 0.4ml in, every day, the oral liquid of every 20g mouse stomach was respectively 0.11g containing crude drug amount, 0.22g, 0.33g, press Mice Body restatement, low dosage, middle dosage and high dose are respectively 5.5g crude drug amount/kg, 11g crude drug amount/kg and 22g crude drug amount/kg.The light capsule of positive drug brain, every day, 70 kilograms of people's consumption was 0.6g, and every day, the consumption of every 20g mice was 0.6*0.0026=0.00156g, pressed Mice Body restatement, and positive drug consumption is 0.078g/kg.
3.4 experiment equipment
YLS-3T type diving tower instrument, the development of Anhui Province Huaibei Zhenghua Biological Instrument Co., Ltd., is separated into Room 5 with opaque Dark grey plastics, every chamber 120mm X 120mm X 180mm, electric gate voltage 100V, electric current 0.05～2.0mA.Right back angle, every chamber is put an insulated platform (high 4.5cm) and as animal, is avoided the safety board of electric shock.ZH-500 type mice is kept away dark instrument, the development of Northern Huaihe River Anhui Zheng Hua biological Instrument and equipments company limited, and experimental provision divides light and shade two Room, and between two Room, having a diameter is the round hole of 3cm size, and two bottoms, Room all spread with copper grid, and darkroom connects electricity.
3.5 diving tower methods
By above-mentioned dosage, carry out administration after 20 days, mice is put into after reaction chamber endoadaptation 3min, pass to 0.25mA electric current electric shock.Record the time (incubation period) of jumping off from platform for the 1st time in mice 5min and the number of times (errors number) jumping off, more on the same group between the difference of mouse memory achievement.The results are shown in Table 1
Table 1 diving tower method is measured Chinese medicine oral liquid of the present invention and mouse memory is reproduced to the impact of obstacle
With normal group comparison,
★p < 0.05; With normal group comparison,
★ ★p < 0.01.
By Biao Ke get, the basic, normal, high dosage group that gives medicine of the present invention can reduce errors number in mice 5 minutes, illustrates that the school grade of mice all presents raising in various degree, and prompting the present invention has the effect of certain memory reinforcing.
3.6 darkness avoidance test
By above-mentioned dosage, carry out administration after 20 days, first mice is put into reaction chamber and adapt to 3min, then the logical 40V of darkroom base copper grid, 50Hz alternating current.Mice is put into bright chamber back to hole, mice enters darkroom and is shocked by electricity.Record the time (incubation period) that enters for the first time darkroom in 5min and enter number of times (errors number).More on the same group between the difference of mouse memory achievement, the results are shown in Table 2
Table 2 darkness avoidance test is investigated the impact of Chinese medicine oral liquid of the present invention on mouse memory
With normal group comparison,
★p < 0.05; With normal group comparison,
★ ★p < 0.01.
By Biao Ke get, the basic, normal, high dosage group that gives medicine of the present invention can reduce errors number in mice 5 minutes, illustrates that the school grade of mice all presents raising in various degree, and prompting the present invention has the effect of certain memory reinforcing.
Zoopery shows, this product all has the effect of obvious promotion learning and memory function to mice, and to sum up, the present invention has obvious effect to strengthening mouse memory power.
Claims (8)
1. the Chinese medicine composition of a memory reinforcing, it is characterized in that, its active component is extracted and is prepared from by following raw materials in part by weight medicine proportioning: Radix Codonopsis 10-30 part, Radix Polygalae 5-15 part, Fructus Gleditsiae Abnormalis 10-20 part, Poria 5-15 part, Semen Ziziphi Spinosae 10-20 part, Radix Angelicae Sinensis 10-30 part and Radix Rehmanniae Preparata 10-30 part.
2. the Chinese medicine composition of memory reinforcing as claimed in claim 1, it is characterized in that, its active component is extracted and to be prepared from by following raw materials in part by weight medicine proportioning: 20 parts, 20 parts of Radix Codonopsis, 10 parts of Radix Polygalaes, 15 parts of Fructus Gleditsiae Abnormalis, 10 parts, Poria, 15 parts of Semen Ziziphi Spinosaes, 20 parts of Radix Angelicae Sinensis and Radix Rehmanniae Preparata.
3. the Chinese medicine composition of memory reinforcing as claimed in claim 1, is characterized in that, described crude drug adds adjuvant after extracting, and with conventional formulation method, makes oral liquid, tablet, capsule or granule.
4. the Chinese medicine composition of memory reinforcing as claimed in claim 3, it is characterized in that, described adjuvant is one or more of dextrin, lactose, starch, sucrose, glucose, microcrystalline Cellulose, mannose, methylcellulose, hydroxypropyl cellulose, carboxymethyl cellulose, stevioside.
5. prepare the method for the Chinese medicine composition of memory reinforcing as claimed in claim 1 for one kind, it is characterized in that, preparation process is: get above-mentioned Radix Codonopsis, Radix Polygalae, Fructus Gleditsiae Abnormalis, Poria, Semen Ziziphi Spinosae, Radix Angelicae Sinensis and Radix Rehmanniae Preparata medical material merge, decoct with water twice, collecting decoction, while being concentrated into 65 ℃, relative density is 1.10-1.20, adding ethanol makes to reach 65-85% containing the percent by volume of alcohol amount, stir, standing, filter, when filtrate decompression is concentrated into 65 ℃, relative density is 1.20-1.30 and reclaims ethanol, obtain concentrated solution, add adjuvant and water is prepared into oral liquid, or concentrated solution spraying is dry, be ground into dry extract, add adjuvant, granulation agent, tablet or capsule.
6. the preparation method of the Chinese medicine composition of memory reinforcing as claimed in claim 5, is characterized in that, decocting condition is: the 8-12 that adds for the first time water and be medical material weight doubly measures, and decocts 1-2h, and the 6-10 that adds for the second time water and be medical material weight doubly measures, and decocts 1-2h.
7. the preparation method of the Chinese medicine composition of memory reinforcing as claimed in claim 5, is characterized in that, described spraying drying condition is: inlet temperature is 100-120 ℃, leaving air temp is 80-90 ℃, temperature of charge is 70-90 ℃, and atomizing pressure is 0.2-0.4 MPa, and spray velocity is 5-10ml/s.
8. the application of the Chinese medicine composition of memory reinforcing in preparing memory reinforcing medicine as claimed in claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210248283.2A CN102727652B (en) | 2012-07-18 | 2012-07-18 | Traditional Chinese medicine composition for enhancing memory as well as preparation method and application of Traditional Chinese medicine composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210248283.2A CN102727652B (en) | 2012-07-18 | 2012-07-18 | Traditional Chinese medicine composition for enhancing memory as well as preparation method and application of Traditional Chinese medicine composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102727652A CN102727652A (en) | 2012-10-17 |
| CN102727652B true CN102727652B (en) | 2014-04-02 |
Family
ID=46984416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210248283.2A Expired - Fee Related CN102727652B (en) | 2012-07-18 | 2012-07-18 | Traditional Chinese medicine composition for enhancing memory as well as preparation method and application of Traditional Chinese medicine composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102727652B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547007A (en) * | 2015-01-27 | 2015-04-29 | 覃春荣 | Traditional Chinese medicine composition for improving memory |
| CN108938764A (en) * | 2017-05-25 | 2018-12-07 | 无限极（中国）有限公司 | It is a kind of to have effects that alleviate Chinese medicine composition of autonomic nervous dysfunction and preparation method thereof and product |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1363307A (en) * | 2001-01-10 | 2002-08-14 | 杨孟君 | Nano medicine 'Guiluningshen' and its preparing process |
| CN1368239A (en) * | 2001-02-01 | 2002-09-11 | 杨孟君 | Nano medicine 'Anshenyangxin' and its preparing process |
| CN101274085A (en) * | 2008-04-22 | 2008-10-01 | 梁进 | Paste for nourishing heart |
| CN101554238A (en) * | 2008-04-10 | 2009-10-14 | 刘泳宏 | Mind-tranquilizing brain-strengthening egg and preparing method thereof |
| CN101564156A (en) * | 2008-04-23 | 2009-10-28 | 刘泳宏 | Natural five color brain-strengthening bean rice and processing method |
-
2012
- 2012-07-18 CN CN201210248283.2A patent/CN102727652B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1363307A (en) * | 2001-01-10 | 2002-08-14 | 杨孟君 | Nano medicine 'Guiluningshen' and its preparing process |
| CN1368239A (en) * | 2001-02-01 | 2002-09-11 | 杨孟君 | Nano medicine 'Anshenyangxin' and its preparing process |
| CN101554238A (en) * | 2008-04-10 | 2009-10-14 | 刘泳宏 | Mind-tranquilizing brain-strengthening egg and preparing method thereof |
| CN101274085A (en) * | 2008-04-22 | 2008-10-01 | 梁进 | Paste for nourishing heart |
| CN101564156A (en) * | 2008-04-23 | 2009-10-28 | 刘泳宏 | Natural five color brain-strengthening bean rice and processing method |
Non-Patent Citations (2)
| Title |
|---|
| 中药促进记忆的临床研究进展;李辉等;《中国康复》;20091031;第24卷(第5期);350-351 * |
| 李辉等.中药促进记忆的临床研究进展.《中国康复》.2009,第24卷(第5期), |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102727652A (en) | 2012-10-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102423072B (en) | Health care food for improving memory and preparation method thereof | |
| CN102870981A (en) | Method for preparing Chinese herbal medicine additive in layer feed | |
| CN102302091A (en) | Chinese herb medicine feed additive used for treating low sexual function of male breeding poultry and preparation method thereof | |
| CN103110846B (en) | Traditional Chinese medical composition for treating hyperlipemia as well as preparation method and application thereof | |
| CN105395665A (en) | Chinese herbal medicine composition capable of preventing and treating fish and shrimp white stool | |
| CN104107269A (en) | Functional blood sugar-reduction health product and preparation method thereof | |
| CN103155985B (en) | Rhizoma polygonati nutrition powder and preparation method thereof | |
| CN102961596A (en) | Traditional Chinese medicine composition for treating diabetes as well as preparation method and application of for traditional Chinese medicine composition | |
| CN102935133B (en) | Traditional Chinese medicine composition for treating rheumatic arthritis as well as preparation method and application thereof | |
| CN102727652B (en) | Traditional Chinese medicine composition for enhancing memory as well as preparation method and application of Traditional Chinese medicine composition | |
| CN107259564A (en) | deficiency of yang health composition and preparation method thereof | |
| CN105918946A (en) | Red date and Chinese wolfberry fruit liver tonifying composition, granules and preparation method thereof | |
| CN113116801B (en) | Composition for improving skin sub-health state and preparation method thereof | |
| CN102935152B (en) | Traditional Chinese medicine composition for treating hyperlipidaemia as well as preparation method and application thereof | |
| CN102302609A (en) | Compound traditional Chinese drug preparation for improving subhealth | |
| CN107961272B (en) | Traditional Chinese medicine composition for treating chronic kidney diseases | |
| CN103127437B (en) | Traditional Chinese medicine composition having hypoglycemic effect | |
| CN102488881B (en) | Compound propolis composition for promoting pig growth and fattening as well as its preparation method | |
| CN103494894B (en) | A kind of have Chinese medicine composition reducing blood glucose effect and its preparation method and application | |
| CN103919845B (en) | A kind of pharmaceutical composition for improving anoxia endurance and its preparation method and application | |
| CN106387514A (en) | Traditional Chinese medicine feed additive for fish and preparation method thereof | |
| CN103494916B (en) | Traditional Chinese medicine composition with effect of reducing blood sugar, as well as preparation method and application thereof | |
| CN106309736A (en) | Anti-fatigue traditional Chinese medicine composition as well as preparation method and application thereof | |
| CN102274348A (en) | Chinese medicinal composition for relieving physical fatigue and preparation method thereof | |
| CN102058771A (en) | Chinese medicine preparation for treating insomnia and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140402 Termination date: 20150718 |
|
| EXPY | Termination of patent right or utility model |