CN102727519A - External diatomite medicament and preparation method thereof - Google Patents
External diatomite medicament and preparation method thereof Download PDFInfo
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- CN102727519A CN102727519A CN2012102359359A CN201210235935A CN102727519A CN 102727519 A CN102727519 A CN 102727519A CN 2012102359359 A CN2012102359359 A CN 2012102359359A CN 201210235935 A CN201210235935 A CN 201210235935A CN 102727519 A CN102727519 A CN 102727519A
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- diatomite
- kieselguhr
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Abstract
The invention discloses an external diatomite medicament and a preparation method thereof, wherein the external medicament diatomite is composed of the following components: below 10000 meshes of diatomite, below 2000 meshes of bentonite, below2000 meshes of kaolin, below 2000 meshes of activated clay, below 800 meshes of sepiolite, below 800 meshes of medical stone powder, and below 800 meshes of attapulgite. The preparation method comprises the following steps of processing the ores into the powder, and then mixing according to the proportion to form spherical, block or mud-shaped products. The invention uses the diatomite and other porous natural materials with absorbing capacity to form the medical medicament for treating injury, can directly absorb the wound bacteria and ulcerated wound substances from the wounded part due to the powerful adsorptivity of diatomite and other materials, so as to absorb and remove the germs and the like at the wound to achieve the purpose of quickening the wound healing. Meanwhile, due to the nanometer-scale fine micropore structure of the diatomite, the germs can be absorbed and decomposed, so as to achieve the elimination purpose. The treatment mechanism is adopted the physical mode, so as to avoid the side effect caused by the common chemical treatment medicine.
Description
[technical field]
The present invention relates to topical agent, relate in particular to a kind of kieselguhr topical agent that is used for the wound treatment and preparation method thereof.
[background technology]
For various dermatosiss such as eczema, paronychia, tinea unguium, scald antiinflammatory, incised wound antiinflammatory, acne, mosquito bite, decubital ulcers all is because bacterial inflammation.General Therapeutic Method all is the therapeutic modality of administered through oral or external used medicine.Often these chemicalses can bring certain side effect simultaneously, bring infringement to healthy, and due to illness untoward reaction such as allergy appear in people's body constitution reason.
In addition, normally clean through antiseptic gauze or cotton swab wiping for the manner of cleaning up of wound, poor because of the adsorption effect of Cotton Gossypii or gauze, cleaning performance is bad.And, patient is brought wound pain at wiping cleaning process shake-up wound.
[summary of the invention]
The technical problem that the present invention will solve provides a kind of kieselguhr topical agent of wound treatment.
The another one technical problem that the present invention will solve provides a kind of method for preparing of kieselguhr topical agent.
For the kieselguhr topical agent, the technical scheme that the present invention adopts is that a kind of kieselguhr topical agent is used for the wound treatment, is composed of the following components:
The following kieselguhr of 10000 orders, the following bentonite of 2000 orders, the following Kaolin of 2000 orders, the following active hargil of 2000 orders, the following meerschaum of 800 orders, the following Maifanitum powder of 800 orders, the following attapulgite of 800 orders.
As preferably, above-mentioned kieselguhr topical agent, form by the following component of meter by ratio of weight and the number of copies:
4～10 parts in the following kieselguhr of 10000 orders;
1～5 part of the following bentonite of 2000 orders;
3～4 parts of the following Kaolin of 2000 orders;
5～6 parts of the following active hargil of 2000 orders;
1～4 part of the following meerschaum of 800 orders;
1～3 part in the following Maifanitum powder of 800 orders;
4～5 parts of the following attapulgites of 800 orders.
For the method for preparing of kieselguhr topical agent, the technical scheme that the present invention adopts is that said method for preparing may further comprise the steps:
(1) with said Ore through fragmentation, washup, pulp, desanding, classification, screening, bleaching, filtration, last spray-dried 800 orders～10000 order products;
(2) after all material mixes in proportion in will filling a prescription,, do glomeration, bulk or mud shape, pack subsequent use through sterilization treatment.
As preferably, the sterilizing methods described in the step (2) adopts xeothermic or radiation sterilization method.
Main material performance of the present invention is following:
1) diatom is a kind of unicellular alga that occurs on earth the earliest, and existence is in sea water or lake water, and body is very small, generally has only several microns to tens microns.Diatom can carry out photosynthesis, the self-control Organic substance.Growth and breeding with surprising rapidity usually.Its remains formation of deposits kieselguhr.The kieselguhr main component is a silicic acid matter, and there are countless pores on the surface, has stronger absorption, decomposition, and cost is not high yet.
2) bentonite is to be main moisture clay pit with the Montmorillonitum.Montmorillonitum has adsorptivity and cation exchange property, good water-swelling property and dispersion and suspension is arranged and make slurry property, and good cohesive force is arranged.
3) Kaolin: the pure Kaolin of matter have whiteness height, matter soft, be prone to dispersion suspension in water, good plasticity and high caking property, excellent electric insulation performance; Have good antiacid dissolubility, very low cation exchange capacity (CEC), physicochemical property such as fire resistance preferably.Therefore Kaolin has become tens necessary raw mineral materials of industry such as papermaking, pottery, rubber, chemical industry, coating, medicine and national defence.
4) active hargil: active hargil is to be raw material with clay (mainly being bentonite), through inorganic acidification, and the adsorbent of processing through water rinse, drying again; Outward appearance is an off-white powder, and odorless is tasteless; Nontoxic, absorption property is very strong, can be adsorbed with color substance, organic substance.In air, be prone to the moisture absorption, placed for a long time and can reduce absorption property.
5) meerschaum be a kind of tool layer chain structure contain Shuifu County's magnesium silicate clay mineral; Meerschaum has performances such as extremely strong absorption, decolouring and dispersion; High heat stability is also arranged, and heat-resisting quantity can reach 1500-1700 ℃, and formative nature, insulating properties, anti-salinity are all very good.
6) Maifanitum is a kind of natural medicine Ore, contains 18 kinds of trace element such as the necessary potassium of human body, sodium, calcium, magnesium, phosphorus macroelement and zinc, ferrum, selenium, copper, strontium, iodine, fluorine, metasilicic acid.Contain aluminum silicate (Anhydrite) in the Maifanitum, pigment and antibacterial are had absorbability, reach more than 96% like 6 hours internal energy absorption escherichia coli, staphylococcuses, if with the Maifanitum pulverize, ion stripping and adsorption strengthen.
7) attapulgite clay is meant with the attapulgite to be a kind of clay mineral of key component.Attapulgite is earthy, compact massive originates in sedimentary rock and the weathering crust, and color is white in color, canescence, cinerous, celadon or weak silky luster.Soil property is fine and smooth, and oily soapy is arranged, and light weight, property are crisp, and fracture is conchoidal or irregular shape, and water absorption is strong.Tool viscosity and plasticity when wet, dry after-contraction is little, not quite shows crackle, and the water logging bubble collapses diffusing.
The present invention system selects kieselguhr, Kaolin, bentonite, active hargil, Maifanitum powder, meerschaum and these porous of attapulgite clay for use and has the novel topical agent that the natural material of absorbability is combined into; Its main therapeutic modality is to smear this medicament at wound or site of disease; Utilize the powerful adsorptivity of constituent such as kieselguhr in the medicament; Wound antibacterial, the wound material that festers are directly adsorbed from the affected part, thereby the therapeutic purposes that reach accelerating wound are eliminated in absorption such as the pathogenic bacteria of wound and the tissue that rots.Compositions self such as while kieselguhr have nano level fine holes structure, can in absorbing pathogenic bacteria, pathogenic bacteria be decomposed, thereby reach the purpose of eliminating pathogenic bacteria.Because its treatment mechanism is physics mode, so avoided the side effect that general chemotherapeutic agent brought.
[specific embodiment]
Embodiment 1:
Present embodiment is a kind of medical kieselguhr wound medicament that is mainly used in treatment burn, decubital ulcer wound, is made up of the following component of counting by ratio of weight and the number of copies:
10 parts in the following kieselguhr of 10000 orders;
5 parts of the following bentonite of 2000 orders;
3 parts of the following Kaolin of 2000 orders;
6 parts of the following active hargil of 2000 orders;
3 parts of the following meerschaums of 800 orders;
3 parts in the following Maifanitum powder of 800 orders;
4 parts of the following attapulgites of 800 orders.
Process for preparing raw material: Ore is through fragmentation, washup, pulp, desanding, classification, screening, bleaching, filtration, last spray-dried 800 orders～10000 order products.
Finished product processing method: after all material mixes in proportion in will filling a prescription,, do glomeration, bulk or mud shape, pack subsequent use through sterilization treatment.Sterilizing methods can adopt xeothermic or the radiation sterilization method.
Method for using: spherical, block medicament dips in the water that takes a morsel earlier when using, and spreads upon the affected part wound then.Mud shape medicament can directly spread upon the wound affected part.
The clinical therapeutic efficacy statistics:
Present embodiment is mainly used in the wound of treatment burn, decubital ulcer generation, plays the effect of inhaling the bacterium removing the necrotic tissue, accelerating wound healing.
Wherein, treatment burn 121 people, effective 117 people cure 112 people, effective percentage 97%, cure rate 93%.Treatment decubital ulcer 77 people, effective 72 people cure 64 people, effective percentage 94%, cure rate 83%.
Embodiment 2:
Present embodiment is a kind of dermopathic medical kieselguhr wound medicaments such as treatment eczema, acne, spot that are mainly used in, and is made up of the following component of counting by ratio of weight and the number of copies:
6 parts in the following kieselguhr of 10000 orders;
1 part of the following bentonite of 2000 orders;
4 parts of the following Kaolin of 2000 orders;
5 parts of the following active hargil of 2000 orders;
1 part of the following meerschaum of 800 orders;
2 parts in the following Maifanitum powder of 800 orders;
5 parts of the following attapulgites of 800 orders.
Raw material and finished product processing method: identical with embodiment 1.
Method for using: identical with embodiment 1.
The clinical therapeutic efficacy statistics:
Present embodiment is mainly used in dermatosiss such as treatment eczema, acne, spot.
Wherein, treatment eczema 125 people, effective 108 people cure 96 people, effective percentage 86%, cure rate 77%.Treatment acne 72 people, effective 60 people cure 54 people, effective percentage 83%, cure rate 75%.Treatment spot 36 people, effective 33 people cure 28 people, effective percentage 92%, cure rate 78%.
Embodiment 3:
Present embodiment is a kind of medical kieselguhr wound medicament that is mainly used in treatment paronychia, tinea unguium, is made up of the following component of counting by ratio of weight and the number of copies:
4 parts in the following kieselguhr of 10000 orders;
3 parts of the following bentonite of 2000 orders;
3 parts of the following Kaolin of 2000 orders;
6 parts of the following active hargil of 2000 orders;
4 parts of the following meerschaums of 800 orders;
1 part in the following Maifanitum powder of 800 orders;
4 parts of the following attapulgites of 800 orders.
Raw material and finished product processing method: identical with embodiment 1.
Method for using: identical with embodiment 1.
The clinical therapeutic efficacy statistics:
Present embodiment is mainly used in treatment paronychia, tinea unguium.
Wherein, treatment paronychia 64 people, effective 60 people cure 54 people, effective percentage 94%, cure rate 84%; Treatment tinea unguium 53 people, effective 48 people cure 41 people, effective percentage 90%, cure rate 77%.
Claims (4)
1. a kieselguhr topical agent is used for the wound treatment, it is characterized in that, be composed of the following components:
The following kieselguhr of 10000 orders, the following bentonite of 2000 orders, the following Kaolin of 2000 orders, the following active hargil of 2000 orders, the following meerschaum of 800 orders, the following Maifanitum powder of 800 orders, the following attapulgite of 800 orders.
2. kieselguhr topical agent according to claim 1 is characterized in that, is made up of the following component of counting by ratio of weight and the number of copies:
4～10 parts in the following kieselguhr of 10000 orders;
1～5 part of the following bentonite of 2000 orders;
3～4 parts of the following Kaolin of 2000 orders;
5～6 parts of the following active hargil of 2000 orders;
1～4 part of the following meerschaum of 800 orders;
1～3 part in the following Maifanitum powder of 800 orders;
4～5 parts of the following attapulgites of 800 orders.
3. the method for preparing of the said kieselguhr topical agent of claim 1 is characterized in that may further comprise the steps:
(1) with said Ore through fragmentation, washup, pulp, desanding, classification, screening, bleaching, filtration, last spray-dried 800 orders～10000 order products;
(2) after all material mixes in proportion in will filling a prescription,, do glomeration, bulk or mud shape, pack subsequent use through sterilization treatment.
4. method for preparing according to claim 3 is characterized in that: the sterilizing methods described in the step (2) adopts xeothermic or radiation sterilization method.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210235935.9A CN102727519B (en) | 2012-07-03 | 2012-07-03 | External diatomite medicament and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210235935.9A CN102727519B (en) | 2012-07-03 | 2012-07-03 | External diatomite medicament and preparation method thereof |
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| CN102727519A true CN102727519A (en) | 2012-10-17 |
| CN102727519B CN102727519B (en) | 2014-05-14 |
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| CN201210235935.9A Active CN102727519B (en) | 2012-07-03 | 2012-07-03 | External diatomite medicament and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106420911A (en) * | 2016-11-24 | 2017-02-22 | 刘全 | Scald ointment and preparation method thereof |
| CN110368441A (en) * | 2018-04-13 | 2019-10-25 | 史红波 | A kind of the wound healing pulvis and preparation method of quick treatment scald |
| CN110882270A (en) * | 2019-12-09 | 2020-03-17 | 北京幸福益生再生医学科技有限公司 | Pharmaceutical composition containing silicon-based regenerative medical material and preparation method thereof |
-
2012
- 2012-07-03 CN CN201210235935.9A patent/CN102727519B/en active Active
Non-Patent Citations (1)
| Title |
|---|
| 王斌: "南阳麦饭石性能及改性研究", 《中国优秀硕士学位论文全文数据库（电子期刊）》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106420911A (en) * | 2016-11-24 | 2017-02-22 | 刘全 | Scald ointment and preparation method thereof |
| CN110368441A (en) * | 2018-04-13 | 2019-10-25 | 史红波 | A kind of the wound healing pulvis and preparation method of quick treatment scald |
| CN110882270A (en) * | 2019-12-09 | 2020-03-17 | 北京幸福益生再生医学科技有限公司 | Pharmaceutical composition containing silicon-based regenerative medical material and preparation method thereof |
| CN110882270B (en) * | 2019-12-09 | 2021-03-12 | 北京幸福益生再生医学科技有限公司 | Pharmaceutical composition containing silicon-based regenerative medical material and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN102727519B (en) | 2014-05-14 |
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