CN102711748A - 用于治疗青光眼和高眼压症的前列腺素化合物和非甾体抗炎药的药物组合 - Google Patents

用于治疗青光眼和高眼压症的前列腺素化合物和非甾体抗炎药的药物组合 Download PDF

Info

Publication number
CN102711748A
CN102711748A CN2010800511948A CN201080051194A CN102711748A CN 102711748 A CN102711748 A CN 102711748A CN 2010800511948 A CN2010800511948 A CN 2010800511948A CN 201080051194 A CN201080051194 A CN 201080051194A CN 102711748 A CN102711748 A CN 102711748A
Authority
CN
China
Prior art keywords
pharmaceutically acceptable
ocular hypertension
compositions
acceptable salt
glaucoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800511948A
Other languages
English (en)
Chinese (zh)
Inventor
拉杰什·克什沙格尔
钱德拉谢卡尔·卡达姆
普拉温·坎布勒
斯莫·穆达
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micro Labs Ltd
Original Assignee
Micro Labs Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micro Labs Ltd filed Critical Micro Labs Ltd
Publication of CN102711748A publication Critical patent/CN102711748A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN2010800511948A 2009-11-11 2010-11-01 用于治疗青光眼和高眼压症的前列腺素化合物和非甾体抗炎药的药物组合 Pending CN102711748A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN2761/CHE/2009 2009-11-11
IN2761CH2009 2009-11-11
PCT/IN2010/000717 WO2011058579A1 (en) 2009-11-11 2010-11-01 Pharmaceutical combination of prostaglandin compound and nsaid for the treatment of glaucoma and ocular hypertension

Publications (1)

Publication Number Publication Date
CN102711748A true CN102711748A (zh) 2012-10-03

Family

ID=43587393

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800511948A Pending CN102711748A (zh) 2009-11-11 2010-11-01 用于治疗青光眼和高眼压症的前列腺素化合物和非甾体抗炎药的药物组合

Country Status (10)

Country Link
US (1) US20120232140A1 (enExample)
EP (1) EP2498768A1 (enExample)
JP (1) JP2013510845A (enExample)
CN (1) CN102711748A (enExample)
AU (1) AU2010317390A1 (enExample)
BR (1) BR112012010936A2 (enExample)
CA (1) CA2780611A1 (enExample)
MX (1) MX2012005447A (enExample)
RU (1) RU2012124216A (enExample)
WO (1) WO2011058579A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT2765988T (lt) 2011-10-12 2024-11-25 Bausch & Lomb Incorporated Kompozicija akims, kuris sudėtyje yra bromfenako su padidintu biologiniu įsisavinimu
JP6185725B2 (ja) * 2012-02-24 2017-08-23 わかもと製薬株式会社 水性医薬組成物
WO2021001806A1 (en) * 2019-07-04 2021-01-07 Ocular Discovery Ltd. Stable dipyridamole formulations with reduced impurities

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849792A (en) * 1994-12-22 1998-12-15 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
US6011062A (en) * 1994-12-22 2000-01-04 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
US20020103255A1 (en) * 1997-12-19 2002-08-01 Hellberg Mark R. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
US20050119262A1 (en) * 2003-08-21 2005-06-02 Pharmacia Corporation Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020146A1 (es) * 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
DE122011100019I1 (de) * 2003-01-21 2011-11-03 Senju Pharma Co Wassrige flussige zubereitung mit 2-amino-3-(4-bromobenzoyl) phenylessigsaure.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849792A (en) * 1994-12-22 1998-12-15 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
US6011062A (en) * 1994-12-22 2000-01-04 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
US20020103255A1 (en) * 1997-12-19 2002-08-01 Hellberg Mark R. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
US20050119262A1 (en) * 2003-08-21 2005-06-02 Pharmacia Corporation Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent

Also Published As

Publication number Publication date
JP2013510845A (ja) 2013-03-28
BR112012010936A2 (pt) 2017-10-17
CA2780611A1 (en) 2011-05-19
EP2498768A1 (en) 2012-09-19
MX2012005447A (es) 2012-07-20
AU2010317390A1 (en) 2012-06-07
US20120232140A1 (en) 2012-09-13
WO2011058579A1 (en) 2011-05-19
RU2012124216A (ru) 2013-12-20

Similar Documents

Publication Publication Date Title
US9012503B2 (en) Ophthalmic composition
TWI746662B (zh) 眼科用製品及黏度降低抑制方法
JP7076183B2 (ja) ビタミンａを含有するエマルション点眼液
JP5345746B1 (ja) 眼科用組成物
JP2013525508A (ja) 新規な点眼組成物
JP7787129B2 (ja) 眼科組成物
JP6672512B2 (ja) 一酸化窒素放出プロスタミドを含有する眼科用組成物
CN102711748A (zh) 用于治疗青光眼和高眼压症的前列腺素化合物和非甾体抗炎药的药物组合
JP5682005B2 (ja) トラニラスト含有水性組成物
US11400100B2 (en) Effective benzalkonium chloride-free bimatoprost ophthalmic compositions
CA2911983A1 (en) Stable bromfenac solution
US20220354784A1 (en) Stable latanoprost compound ophthalmic compositions
US20170000889A1 (en) Stable bromfenac ophthalmic solution
JP2016027025A (ja) 局所粘膜適用水性組成物
ES2460967T3 (es) Método para la prevención de la degradación de una sustancia térmicamente inestable
JP2014122209A (ja) オロパタジン含有水性組成物
JP5695580B2 (ja) ラタノプロストのバイオアベイラビリティを向上させる方法
US20220370396A1 (en) Methods for modulating conditions of the eye using novel latanoprost compound ophthalmic compositions
JP7586879B2 (ja) 医薬組成物
JP7550014B2 (ja) 医薬組成物
EP2827838A1 (en) Ophthalmic pharmaceutical composition containing a carbonic anhydrase inhibitor and method for the preparation thereof
AU2017235979A1 (en) Non-irritating ophthalmic povidone-iodine compositions
JP2024025725A (ja) 組成物
JP2024025726A (ja) 組成物
JP2011037736A (ja) 眼科用水性組成物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20121003