CN102698134A - Traditional Chinese medicine composition for treating allergic rhinitis and preparation method and application thereof - Google Patents
Traditional Chinese medicine composition for treating allergic rhinitis and preparation method and application thereof Download PDFInfo
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- CN102698134A CN102698134A CN2012101514376A CN201210151437A CN102698134A CN 102698134 A CN102698134 A CN 102698134A CN 2012101514376 A CN2012101514376 A CN 2012101514376A CN 201210151437 A CN201210151437 A CN 201210151437A CN 102698134 A CN102698134 A CN 102698134A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating allergic rhinitis. The traditional Chinese medicine composition is prepared from, by weight, the following raw materials, 10-20 parts of magnolia flower, 12-18 parts of mother chrysanthemum, 12-18 parts of cocklebur fruit, 15-30 parts of centipeda minima, 10-20 parts of ligusticum wallichii, 10-20 parts of astragalus mongholicus, 5-8 parts of semen coicis, 3-6 parts of radix ophiopogonis, 10-20 parts of honeysuckle, 8-12 parts of rhizoma anemarrhenae, 10-16 parts of periostracum cicada, 10-16 parts of lumbricus, 8-12 parts of prunella spike and 10-16 parts of divaricate saposhnikovia root. The medicine for treating the allergic rhinitis is good in treating effect, short in course of treatment, fast in effect, low in price, free of toxic and side effects, simple in preparation method and applicable to clinical application.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, specifically a kind of Chinese medicine composition of treatment of allergic rhinitis.
Background technology
Allergic rhinitis (allergic rhinitis) claim allergic rhinitis again, is the allergic disease of nasal membrane, and can causes multiple complications.From the morbidity persistent period divide, allergic rhinitis often are divided into seasonal rhinitis, perennial rhinitis, intermittent rhinitis; Sneeze, rhinocnesmus, watery nasal discharge and nasal obstruction are modal four big symptoms.In much human, a bit painful, still the same later when allergic rhinitis is only shown effect with healthy subjects, control that it doesn't matter.In fact, allergic rhinitis is if untimely the treatment might be brought out sinusitis, nasal polyp, and long-term treatment is improper, also can cause otitis media, anosmia even bring out asthma.When symptoms such as rhinocnesmus, sneeze, rhinorrhea, nasal obstruction appear in some people at spring and autumn; Take for be change according to the season wear the clothes, " intractable flu " or " pyretic cold " that improper diet causes; Be afraid of again to go hospital admission to expend time in and money; Simply take cold medicine voluntarily, the result causes course of disease delay, finally can be the persistent state of nasal obstruction, watery nasal discharge all the year round.Some patient uses local Decongestant treatment merely, and uses more random because of long-term nasal obstruction; Because this type nasal drop has stronger vasodilation rebound effect usually; Be to cause the modal reason of medicamentous rhinitis, only medication when having an attack of one's old illness of many patients, symptom is slightly once alleviating drug withdrawal; Bad when causing the allergic rhinitis fashion, in addition more and more serious.The method of treatment of allergic rhinitis mainly contains desensitization therapy, hormone or immunotherapy at present; Though but desensitization therapy has good effect, needs very long treatment time, hormone or immunization therapy method be symptomatic treatment when seizure of disease only; Cure the symptoms, not the disease; And along with the prolongation of Time of Administration, and have untoward reaction in various degree, also possibly produce certain drug resistance.
Summary of the invention
Goal of the invention: for the deficiency of customer service prior art, the invention provides that a kind of therapeutic effect is good, the medicine of the treatment of allergic rhinitis of safety, short treating period.
Technical scheme: in order to solve the problems of the technologies described above; The technical scheme that the present invention adopted is: a kind of medicine of treatment of allergic rhinitis, it is mainly processed by following bulk drugs: 10 ~ 20 parts of Flos Magnoliaes, 12 ~ 18 parts of Flos Chrysanthemi Indicis, 12 ~ 18 parts of Fructus Xanthii, 15 ~ 30 parts of Herba Centipedae, 10 ~ 20 parts of Rhizoma Chuanxiongs, 10 ~ 20 parts of the Radixs Astragali, 5 ~ 8 parts of Semen Coiciss, 3 ~ 6 parts of Radix Ophiopogonis, 10 ~ 20 parts of Flos Loniceraes, 8 ~ 12 parts of the Rhizoma Anemarrhenaes, 10 ~ 16 parts of Periostracum Cicadaes, 10 ~ 16 parts of Pheretimas, 8 ~ 12 parts of Spica Prunellaes, windproof 10 ~ 16 parts.
As further improvement of the present invention, the consumption of said each crude drug is: 12 parts of Flos Magnoliaes, 16 parts of Flos Chrysanthemi Indicis, 16 parts of Fructus Xanthii, 20 parts of Herba Centipedae, 12 parts of Rhizoma Chuanxiongs, 12 parts of the Radixs Astragali, 5 parts of Semen Coiciss, 6 parts of Radix Ophiopogonis, 16 parts of Flos Loniceraes, 10 parts of the Rhizoma Anemarrhenaes, 10 parts of Periostracum Cicadaes, 10 parts of Pheretimas, 10 parts of Spica Prunellaes, windproof 10 parts.
The method for preparing of the medicine of above-mentioned treatment of allergic rhinitis may further comprise the steps:
(1) consumption according to each crude drug takes by weighing each crude drug;
(2) head is fried in shallow oil operation: all crude drug in the step (1) are soaked, and the said water yield is 3 ~ 5 times of all crude drug gross weights, soaks 10 ~ 20 minutes, and after big fire was boiled, slow fire continued to decoct 20 ~ 25 minutes, leaches medicinal liquid, obtains filtering residue;
(3) two fry in shallow oil operation: the filtering residue to obtaining in the step (2) is soaked, and this moment, the water yield was 1 ~ 2 times of all crude drug gross weight, and decocting time 20 ~ 30 minutes leaches medicinal liquid;
(4) merge: after frying in shallow oil the medicinal liquid that obtains in the operation and fry in shallow oil the medicinal liquid that obtains in the operation and mix two, promptly get the Chinese medicine composition of said treatment of allergic rhinitis.
The application of above-mentioned Chinese medicine composition in preparation treatment of allergic rhinitis medicine.
Beneficial effect: compared with prior art, the medication effect of treatment of allergic rhinitis provided by the invention is good, short treating period, instant effect; Cheap, have no side effect, and method for preparing is easy, is suitable for clinical practice.
The specific embodiment
According to following embodiment, can understand the present invention better.Yet, those skilled in the art will readily understand that the described concrete material proportion of embodiment, process conditions and result thereof only are used to explain the present invention, and the present invention that should also can not limit in claims to be described in detail.
Embodiment 1: the medicine of a kind of treatment of allergic rhinitis of the present invention; The consumption that comprises following crude drug and each crude drug is respectively: in parts by weight, and 12 parts of Flos Magnoliaes, 16 parts of Flos Chrysanthemi Indicis, 16 parts of Fructus Xanthii, 20 parts of Herba Centipedae, 12 parts of Rhizoma Chuanxiongs, 12 parts of the Radixs Astragali, 5 parts of Semen Coiciss, 6 parts of Radix Ophiopogonis, 16 parts of Flos Loniceraes, 10 parts of the Rhizoma Anemarrhenaes, 10 parts of Periostracum Cicadaes, 10 parts of Pheretimas, 10 parts of Spica Prunellaes, windproof 10 parts.
Said medicine is prepared from through following method: the consumption according to each crude drug takes by weighing each crude drug; All crude drug are added 3 times water logging bubble of crude drug gross weight, soaked 10 minutes, after big fire was boiled, slow fire continued to decoct 20 minutes, leaches medicinal liquid, obtains filtering residue; The water logging that filtering residue is added 2 times of crude drug gross weights is steeped, and decocting time 20 minutes leaches medicinal liquid; Merge twice and decoct the medicinal liquid that obtains in the operation, promptly get the Chinese medicine composition of said treatment of allergic rhinitis.
Said medicine can be made into granule, the capsule of medically approval according to conventional method.
Embodiment 2: the medicine of a kind of treatment of allergic rhinitis of the present invention; The consumption that comprises following crude drug and each crude drug is respectively: in parts by weight, and 10 parts of Flos Magnoliaes, 12 parts of Flos Chrysanthemi Indicis, 12 parts of Fructus Xanthii, 15 parts of Herba Centipedae, 10 parts of Rhizoma Chuanxiongs, 10 parts of the Radixs Astragali, 6 parts of Semen Coiciss, 3 parts of Radix Ophiopogonis, 10 parts of Flos Loniceraes, 8 parts of the Rhizoma Anemarrhenaes, 12 parts of Periostracum Cicadaes, 12 parts of Pheretimas, 8 parts of Spica Prunellaes, windproof 12 parts.
Said medicine is prepared from through following method: the consumption according to each crude drug takes by weighing each crude drug; All crude drug are added 5 times water logging bubble of crude drug gross weight, soaked 20 minutes, after big fire was boiled, slow fire continued to decoct 25 minutes, leaches medicinal liquid, obtains filtering residue; The water logging that filtering residue is added 1 times of crude drug gross weight is steeped, and decocting time 30 minutes leaches medicinal liquid; Merge twice and decoct the medicinal liquid that obtains in the operation, promptly get the Chinese medicine composition of said treatment of allergic rhinitis.
Embodiment 3: basic identical with embodiment 1, different is the consumption of crude drug: 20 parts of Flos Magnoliaes, 18 parts of Flos Chrysanthemi Indicis, 18 parts of Fructus Xanthii, 30 parts of Herba Centipedae, 20 parts of Rhizoma Chuanxiongs, 20 parts of the Radixs Astragali, 8 parts of Semen Coiciss, 4 parts of Radix Ophiopogonis, 20 parts of Flos Loniceraes, 12 parts of the Rhizoma Anemarrhenaes, 16 parts of Periostracum Cicadaes, 16 parts of Pheretimas, 12 parts of Spica Prunellaes, windproof 16 parts.
Below come further to set forth the beneficial effect of medicine according to the invention through clinical case.
With test group treatment of allergic rhinitis 50 examples, compare with matched group 50 examples.
Test group:The Chinese medicine composition described in the embodiment 1-3 is decocted in water for oral dose among the present invention, every day potion, sub-service sooner or later.Taking medicine continuously 14 days is 1 course of treatment, and further consultation in per 14 days once.Be 4 courses of treatment observing time.
Matched group:Adopt conventional nasal drop to treat, every day three times, 14 days was 1 course of treatment.Be 4 courses of treatment observing time.
Criterion of therapeutical effect is drafted with reference to State Administration of Traditional Chinese Medicine's " traditional Chinese medical science disease diagnosis criterion of therapeutical effect ":
1, cure: clinical symptom disappearance, there is not the recidivist after following up a case by regular visits to half a year;
2, produce effects: clinical symptoms, sign obviously alleviate, and receiving anaphylactogen once in a while stimulates, and slightly have a stuffy nose again or flow a little clear nasal mucus;
3, effective: clinical symptoms, sign alleviate, and seizure frequency reduces, and the outbreak persistent period is shorter;
4, invalid: symptom, sign do not have the improvement or the person of increasing the weight of.
Test group and matched group curative effect are relatively seen table 1.
Table 1 test group and matched group curative effect are relatively
| ? | Clinical recovery | Produce effects | Effectively | Invalid | Add up to | Effective percentage (%) |
| Test group | 10 | 20 | 18 | 2 | 50 | 96 |
| Matched group | 2 | 10 | 15 | 23 | 50 | 54 |
Test group treatment of allergic rhinitis 50 examples, total effective rate reaches 96%, with matched group 50 routine total effective rates 54%, compares, and is superior to matched group greatly.Explain that Drug therapy allergic rhinitis of the present invention is evident in efficacy, have good promotional value.
Claims (4)
1. the Chinese medicine composition of a treatment of allergic rhinitis; It is characterized in that it is mainly processed by following bulk drugs: 10 ~ 20 parts of Flos Magnoliaes, 12 ~ 18 parts of Flos Chrysanthemi Indicis, 12 ~ 18 parts of Fructus Xanthii, 15 ~ 30 parts of Herba Centipedae, 10 ~ 20 parts of Rhizoma Chuanxiongs, 10 ~ 20 parts of the Radixs Astragali, 5 ~ 8 parts of Semen Coiciss, 3 ~ 6 parts of Radix Ophiopogonis, 10 ~ 20 parts of Flos Loniceraes, 8 ~ 12 parts of the Rhizoma Anemarrhenaes, 10 ~ 16 parts of Periostracum Cicadaes, 10 ~ 16 parts of Pheretimas, 8 ~ 12 parts of Spica Prunellaes, windproof 10 ~ 16 parts.
2. the Chinese medicine composition of treatment of allergic rhinitis according to claim 1; It is characterized in that the consumption of said each crude drug is: 12 parts of Flos Magnoliaes, 16 parts of Flos Chrysanthemi Indicis, 16 parts of Fructus Xanthii, 20 parts of Herba Centipedae, 12 parts of Rhizoma Chuanxiongs, 12 parts of the Radixs Astragali, 4 parts of Semen Coiciss, 6 parts of Radix Ophiopogonis, 16 parts of Flos Loniceraes, 10 parts of the Rhizoma Anemarrhenaes, 10 parts of Periostracum Cicadaes, 10 parts of Pheretimas, 10 parts of Spica Prunellaes, windproof 10 parts.
3. the method for preparing of the Chinese medicine composition of the described treatment of allergic rhinitis of claim 1 is characterized in that, may further comprise the steps: this method comprises the steps:
(1) consumption according to each crude drug takes by weighing each crude drug;
(2) head is fried in shallow oil operation: all crude drug in the step (1) are soaked, and the said water yield is 3 ~ 5 times of all crude drug gross weights, soaks 10 ~ 20 minutes, and after big fire was boiled, slow fire continued to decoct 20 ~ 25 minutes, leaches medicinal liquid, obtains filtering residue;
(3) two fry in shallow oil operation: the filtering residue to obtaining in the step (2) is soaked, and this moment, the water yield was 1 ~ 2 times of all crude drug gross weight, and decocting time 20 ~ 30 minutes leaches medicinal liquid;
(4) merge: after frying in shallow oil the medicinal liquid that obtains in the operation and fry in shallow oil the medicinal liquid that obtains in the operation and mix two, promptly get the Chinese medicine composition of said treatment of allergic rhinitis.
4. the application of the said Chinese medicine composition of claim 1 in preparation treatment of allergic rhinitis medicine.
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| CN201210151437.6A CN102698134B (en) | 2012-05-16 | 2012-05-16 | Traditional Chinese medicine composition for treating allergic rhinitis and preparation method and application thereof |
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| CN102698134B CN102698134B (en) | 2014-01-01 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104013677A (en) * | 2014-06-23 | 2014-09-03 | 张大威 | Liquid medicine for preventing and treating allergic rhinitis and wet tissue or tissue prepared by applying liquid medicine |
| CN106075234A (en) * | 2016-08-08 | 2016-11-09 | 田丰 | A kind of double pungent ' Biyanwan ' for treating rhinitis |
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| CN101259242A (en) * | 2008-04-17 | 2008-09-10 | 赵开峰 | Medicine for treating allergic rhinitis |
| CN101637546A (en) * | 2009-08-20 | 2010-02-03 | 曹书光 | Medicine for treating acute and chronic rhinitis and sinusitis |
| CN101991818A (en) * | 2009-08-20 | 2011-03-30 | 霍景良 | Medicament for treating and resisting allergic diseases |
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Patent Citations (4)
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| CN1751730A (en) * | 2004-09-20 | 2006-03-29 | 曹蛟 | Traditional Chinese medicine for treating anaphylactic rhinitis and its prepn. method |
| CN101259242A (en) * | 2008-04-17 | 2008-09-10 | 赵开峰 | Medicine for treating allergic rhinitis |
| CN101637546A (en) * | 2009-08-20 | 2010-02-03 | 曹书光 | Medicine for treating acute and chronic rhinitis and sinusitis |
| CN101991818A (en) * | 2009-08-20 | 2011-03-30 | 霍景良 | Medicament for treating and resisting allergic diseases |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104013677A (en) * | 2014-06-23 | 2014-09-03 | 张大威 | Liquid medicine for preventing and treating allergic rhinitis and wet tissue or tissue prepared by applying liquid medicine |
| CN104013677B (en) * | 2014-06-23 | 2017-10-17 | 张大威 | Decoction and the wet tissue or paper handkerchief using its preparation for preventing and treating allergic rhinitis |
| CN106075234A (en) * | 2016-08-08 | 2016-11-09 | 田丰 | A kind of double pungent ' Biyanwan ' for treating rhinitis |
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| CN102698134B (en) | 2014-01-01 |
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