CN102696635A - Bactericidal composition containing fluazinam and methoxyacrylates - Google Patents
Bactericidal composition containing fluazinam and methoxyacrylates Download PDFInfo
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- CN102696635A CN102696635A CN2012101992823A CN201210199282A CN102696635A CN 102696635 A CN102696635 A CN 102696635A CN 2012101992823 A CN2012101992823 A CN 2012101992823A CN 201210199282 A CN201210199282 A CN 201210199282A CN 102696635 A CN102696635 A CN 102696635A
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Abstract
The invention discloses a bactericidal composition containing fluazinam and methoxyacrylates. The bactericidal composition contains an active ingredient A and an active ingredient B, wherein the active ingredient A is the fluazinam; the active ingredient B is one of the following compounds: picoxystrobin, metominostrobin, orysastrobin, fluoxastrobin, trifloxystrobin and kresoxim-methyl; and the weight ratio of the active ingredient A to the active ingredient B is (1:60)-(80:1). The composition has relatively high activity on multiple diseases on multiple kinds of crops, has a remarkable synergistic effect, broadens a bactericidal spectrum, and has the characteristics of low dosage, rainwash resistance and remarkable synergism.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on crop pest that contains fluazinam and methoxy acrylic.
Technical background
Fluazinam (fluazinam) chemical name: 3-chloro-N-(3-chloro-5-trifluoromethyl-2-pyridine radicals)-α, α, α-three fluoro-2,6-dinitro-ρ-toluidines.Fluazinam is for belonging to 2, and the 6-dinitroanilines is a protective fungicide, and mitochondrial phosphorous oxide acidylate uncoupler suppresses spore germination, and mycelia formation, growth and steamed stuffed bun form.Treatment and systemic action are arranged, and the ability of residual effect and resistance of rainwater washing against is strong.
Methoxy acrylic is to be one type of new type bactericide of lead compound exploitation with natural methoxy acrylate antibiotic; It is the mitochondrial respiratory inhibitor of disease fungus; Promptly through shifting consistent mitochondrial breathing at electronics between cytochrome b and c1; The interference cell energy is supplied with, and makes cell death, thus the performance bactericidal action.
In the real process of agricultural production, preventing and treating the problem that disease is easy to generate most is the generation of disease drug resistance.The different cultivars composition carries out composite, is to prevent and treat the very common method of resistance disease.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals all is an additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor's research; Discovery is composite each other with fluazinam and ZEN 90160, SSF 126, orysastrobin, fluoxastrobin, oxime bacterium ester, kresoxim-methyl; Good synergistic effect is arranged within the specific limits; And relevant composite about fluazinam and ZEN 90160, SSF 126, orysastrobin, fluoxastrobin, oxime bacterium ester, kresoxim-methyl, do not see relevant report at present at home and abroad as yet.
Summary of the invention
The objective of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good bactericidal composition that contains fluazinam and methoxy acrylic.
The present invention realizes through following technical scheme:
A kind of bactericidal composition that contains fluazinam and methoxy acrylic; Contain active components A and active component B; Active components A and active component B weight ratio are 1: 60～80: 1; Described active components A is selected from fluazinam, and active component B is selected from a kind of in ZEN 90160, SSF 126, orysastrobin, fluoxastrobin, oxime bacterium ester, the kresoxim-methyl; The preferred weight ratio of active components A and active component B is 1 ︰, 40～60 ︰ 1; More preferably the weight ratio of fluazinam and ZEN 90160 is 1: 20～20: 1; The weight ratio of fluazinam and SSF 126 is 1: 10～30: 1; The weight ratio of fluazinam and orysastrobin is 1: 10～20: 1; The weight ratio of fluazinam and fluoxastrobin is 1: 10～20: 1, and the weight ratio of fluazinam and oxime bacterium ester is 1 ︰, 10～20 ︰ 1, and the weight ratio of fluazinam and kresoxim-methyl is 1 ︰, 10～20 ︰ 1; The weight ratio that most preferably is fluazinam and ZEN 90160 is 1: 10～10: 1; The weight ratio of fluazinam and SSF 126 is 1: 5～15: 1; The weight ratio of fluazinam and orysastrobin is 1: 5～10: 1; The weight ratio of fluazinam and fluoxastrobin is 1: 5～10: 1, and the weight ratio of fluazinam and oxime bacterium ester is 1 ︰, 5～10 ︰ 1, and the weight ratio of fluazinam and kresoxim-methyl is 1 ︰, 5～10 ︰ 1.
The described bactericidal composition that contains fluazinam and methoxy acrylic, composition is processed wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
The described bactericidal composition that contains fluazinam and methoxy acrylic is used to prevent and treat the disease of crop, and described crop comprises cereal crops, legume crop, fiber crop, sugar [yielding, melon crop, fruits crop, dry fruit crop, hobby crop, root crop, oil crop, flowers crop, medicinal crop, raw material crop, green manure pasture crop.
Described disease comprises downy mildew, peronospora tabacina, early blight, late blight, gray mold, powdery mildew, rice blast, damping off, rust, white rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthracnose, spot defoliation, spike rot, club root, stalk break.
Amount of application when the content of active component depends on independent use in the bactericidal composition of the present invention also depends on the mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target disease.Usually the weight percentage of active component is 1%～90% of a gross weight in the composition, and preferable is 5%～80%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1%～60% active substance by weight, preferably is 5%～50%; Solid pharmaceutical preparation contains 5%～80% active substance by weight, preferably is 10%～80%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 2%～30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The surfactant that bactericidal composition of the present invention is selected for use is known in those skilled in the art: can be selected from dispersant, wetting agent, thickener or the antifoaming agent one or more.According to different dosage form, can also contain stabilizing agent known in those skilled in the art, antifreeze etc. in the preparation.
The bactericidal composition of invention can be by the user before use through dilution or directly use.Its preparation can be by processing method known in those skilled in the art preparation, is about to active component and after liquid flux or solid carrier mix, and adds in surfactant such as dispersant, stabilizing agent, wetting agent, binding agent, the antifoaming agent etc. one or more again.
When processing wetting powder, composition comprises following component and content: active components A 0.5% ~ 80%, active component B 0.5% ~ 60%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, filler surplus.
When processing water dispersible granules, composition comprises following component and content: active components A 0.5% ~ 80%, active component B 0.5% ~ 60%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0 ~ 8%, filler surplus.
Comprise following component and content when composition is processed suspending agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, dispersant 1% ~ 10%, wetting agent 1% ~ 10%, antifoaming agent 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Comprise following component and content when composition is processed aqueous emulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, solvent 1% ~ 20%, emulsifier 1% ~ 12%, antifreeze 0 ~ 8%, antifoaming agent 0.01% ~ 2%, thickener 0 ~ 2%, deionized water add to 100%.
Comprise following component and content when composition is processed microemulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, emulsifier 3% ~ 25%, solvent 1% ~ 10%, antifreeze 0 ~ 8%, antifoaming agent 0.01% ~ 2%, deionized water add to 100%.
Comprise following component and content when composition is processed suspension emulsion: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, emulsifier 1% ~ 10%, dispersant 1% ~ 10%, solvent 1% ~ 20%, antifoaming agent 0.01% ~ 2%, thickener 0 ~ 2%, antifreeze 0 ~ 8%, deionized water add to 100%.
Comprise following component and content when composition is processed microcapsule suspending agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, macromolecule cyst material 1% ~ 10%, dispersant 2% ~ 10%, solvent 1% ~ 10%, emulsifier 1% ~ 7%, pH regulator agent 0.01% ~ 5%, antifoaming agent 0.01% ~ 2%, deionized water add to 100%.
Composition comprises following component and content when processing microcapsule suspension-suspending agent: active components A 0.5% ~ 50%, active component B 0.5% ~ 50%, macromolecule cyst material 1% ~ 12%, dispersant 1% ~ 12%, wetting agent 1% ~ 8%, solvent 1% ~ 15%, emulsifier 1% ~ 8%, antifoaming agent 0.01% ~ 2%, thickener 0 ~ 2%, pH regulator agent 0.01% ~ 5%, deionized water add to 100%.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Microcapsule suspending agent the key technical indexes of the present invention:
Microcapsule suspension of the present invention-suspending agent the key technical indexes:
The invention has the advantages that:
(1) present composition has good synergy and lasting effect within the specific limits, and preventive effect is higher than single agent; (2) the agricultural chemicals dosage reduces, and reduces the residual quantity of agricultural chemicals on crop, alleviates environmental pollution; (3) enlarged fungicidal spectrum, multiple diseases such as downy mildew, peronospora tabacina, early blight, late blight, gray mold, powdery mildew, rice blast, damping off, rust, white rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthracnose, spot defoliation, spike rot, club root, stalk break have all been had greater activity.
Embodiment
The present invention is explained further that the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
Application implementation example one
Embodiment 1 ~ 14 wetting powder
Fluazinam, active component B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into wetting powder product of the present invention.Specifically see table 1,2.
Table 1 embodiment 1 ~ 7 each component and content
Table 2 embodiment 8 ~ 14 each component and content
Embodiment 15 ~ 28 water dispersible granules
Fluazinam, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add binding agent (can add and not add) again to wait other auxiliary agent, obtain the materials of granulating.After will expecting that article are quantitatively sent interior process granulation of fluidized bed granulation dryer and drying to, can make water dispersible granules product of the present invention, specifically see table 3,4.
Table 3 embodiment 15 ~ 21 each component and content
Table 4 embodiment 22 ~ 28 each component and content
Embodiment 29 ~ 42 suspending agents
With dispersant, wetting agent, antifoaming agent, thickener (can add and not add), antifreeze (can add and not add); Mix through high speed shear, add fluazinam, active component B, ball milling is 2 ~ 3 hours in ball mill; Make diameter of particle all below 5 μ m; Surplus is supplied with deionized water, can make suspending agent product of the present invention, specifically sees table 5,6.
Table 5 embodiment 29 ~ 35 each component and content
Table 6 embodiment 36 ~ 42 each component and content
Embodiment 43 ~ 56 aqueous emulsions
Fluazinam, active component B, solvent, emulsifier are added together, make and be dissolved into even oil phase; Deionized water, antifreeze (can add and can not add), thickener (can add and can not add), antifoaming agent are mixed, become the homogeneous water.Under high-speed stirred, water is added oil phase, make aqueous emulsion product of the present invention.Specifically see table 7,8.
Table 7 embodiment 43 ~ 49 each component and content
Table 8 embodiment 50 ~ 56 each component and content
Embodiment 57 ~ 63 microemulsions
Fluazinam, active component B are dissolved in the homogenizer that solvent is housed; With emulsifier, antifreeze (can add and can not add), antifoaming agent, join in the homogenizer that above-mentioned solution is housed; Surplus is given intense mixing and homogenize after supplying with deionized water, obtains the as clear as crystal microemulsion product of the present invention of outward appearance at last.Specifically see table 9.
Table 9 embodiment 57 ~ 63 each component and content
Embodiment 64 ~ 70 suspension emulsions
Dispersant, antifoaming agent, thickener (can add and can not add), antifreeze (can add and can not add) are mixed through high speed shear; Add fluazinam; Ball milling is 2 ~ 3 hours in ball mill, makes diameter of particle all below 5 μ m, makes the fluazinam suspending agent; Then with active component B, emulsifier, solvent and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make suspension emulsion product of the present invention.Specifically see table 10.
Table 10 embodiment 64 ~ 70 each component and content
ZEN 90160, SSF 126, orysastrobin, fluoxastrobin, oxime bacterium ester, kresoxim-methyl in table 1 ~ 10 are exchanged, can make novel formulation.
Embodiment 71 ~ 73 microcapsule suspending agents
With fluazinam, active component B, macromolecule cyst material, solvent; Make and be dissolved into even oil phase, under shearing condition, oil phase is joined in the aqueous phase solution that contains emulsifier, pH regulator agent, dispersant, antifoaming agent; Surplus is supplied with deionized water; Two kinds of materials react at oil-water interfaces, form the macromolecule cyst wall, process the finely disseminated microcapsule suspending agent product of the present composition.Specifically see table 11.
Table 11 embodiment 71 ~ 73 each component and content
Embodiment 74 ~ 76 microcapsule suspensions-suspending agent
With active component B, macromolecule cyst material, solvent, make and be dissolved into even oil phase, oil phase is joined under shearing condition in the aqueous phase solution that contains emulsifier, pH regulator agent, process finely disseminated microcapsule suspending agent.Dispersant, wetting agent, antifoaming agent, thickener (can add and can not add) are mixed through high speed shear; Add fluazinam, ball milling is 2 ~ 3 hours in ball mill, makes diameter of particle all below 5 μ m; Make suspending agent; Then suspending agent is joined in the aqueous phase solution of micro-capsule suspension, deionized water is supplied surplus, processes the finely disseminated microcapsule suspension of the present composition-suspending agent product.Specifically see table 12.
Table 12 embodiment 74 ~ 76 each component and content
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
Test method: after the effective inhibition concentration scope of each medicament was confirmed in prerun, medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the crop germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is following:
Wherein: a, b are respectively active components A and active component B shared ratio in combination;
A is a fluazinam;
B is selected from a kind of in ZEN 90160, SSF 126, orysastrobin, fluoxastrobin, oxime bacterium ester, the kresoxim-methyl.
Application implementation example two:
Supply the examination disease: capsicum epidemic disease, test medicine provides experimental scheme by Shaanxi agricultural chemicals Co., Ltd of U.S. nation: effective inhibition concentration scope of confirming the two different proportioning mixture of fluazinam and ZEN 90160 through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table of table 13 fluazinam and ZEN 90160 to capsicum epidemic disease
Can know by table 13; The proportioning of the composite control capsicum epidemic disease of fluazinam and ZEN 90160 is when 1 ︰, 60 ~ 80 ︰ 1; Synergy ratio SR is all greater than 1.5, explains that both are mixed all to show synergistic effect in 1 ︰, 60 ~ 80 ︰, 1 scope, and the proportioning of fluazinam and ZEN 90160 was at 1: 20～20: 1; Synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing the proportioning of finding fluazinam and ZEN 90160 through the applicant is 20 ︰, 1,15 ︰, 1,10 ︰, 1,9 ︰, 1,8 ︰, 1,7 ︰, 1,6 ︰, 1,5 ︰, 1,4 ︰, 1,3 ︰, 1,2 ︰, 1,1 ︰, 1,1 ︰, 2,1 ︰, 3,1 ︰, 4,1 ︰, 5,1 ︰, 6,1 ︰, 7,1 ︰, 8,1 ︰, 9,1 ︰, 10,1 ︰, 15,1 ︰ 20; Synergy ratio was maximum when wherein fluazinam and ZEN 90160 weight ratio were 1:1, and synergistic effect is the most obvious.
Application implementation example three:
Supply the examination disease: grey mould fruit rot of strawberry, test medicine provides experimental scheme by Shaanxi agricultural chemicals Co., Ltd of U.S. nation: effective inhibition concentration scope of confirming the former medicine of fluazinam and SSF 126 and the two different proportioning mixture through preliminary experiment
Toxicity test result
The composite toxicity test analysis of results table of table 14 fluazinam and SSF 126 to grey mould fruit rot of strawberry
Can know by table 14; The proportioning of the composite control grey mould fruit rot of strawberry of fluazinam and SSF 126 is when 1 ︰, 60 ~ 80 ︰ 1; Synergy ratio SR is all greater than 1.5, explains that both are mixed all to show synergistic effect in 1 ︰, 60 ~ 80 ︰, 1 scope, and the proportioning of fluazinam and SSF 126 is at 1 ︰ 10～30: 1; Synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing the proportioning of finding fluazinam and SSF 126 through the applicant is 30 ︰, 1,25 ︰, 1,20 ︰, 1,15 ︰, 1,10 ︰, 1,9 ︰, 1,8 ︰, 1,7 ︰, 1,6 ︰, 1,5 ︰, 1,4 ︰, 1,3 ︰, 1,2 ︰, 1,1 ︰, 1,1 ︰, 2,1 ︰, 3,1 ︰, 4,1 ︰, 5,1 ︰, 6,1 ︰, 7,1 ︰, 8,1 ︰, 9,1 ︰ 10; Synergy ratio was maximum when wherein fluazinam and SSF 126 weight ratio were 3:1, and synergistic effect is the most obvious.
Application implementation example four:
Supply the examination disease: potato late blight, test medicine provides experimental scheme by Shaanxi agricultural chemicals Co., Ltd of U.S. nation: effective inhibition concentration scope of confirming the former medicine of fluazinam and orysastrobin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table of table 15 fluazinam and orysastrobin to potato late blight
Can know by table 15; The proportioning of the composite control potato late blight of fluazinam and orysastrobin is when 1 ︰, 60 ~ 80 ︰ 1; Synergy ratio SR is all greater than 1.5, explains that both are mixed all to show synergistic effect in 1 ︰, 60 ~ 80 ︰, 1 scope, and the proportioning of fluazinam and orysastrobin was at 1: 10～20: 1; Synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing the proportioning of finding fluazinam and orysastrobin through the applicant is 20 ︰, 1,15 ︰, 1,10 ︰, 1,9 ︰, 1,8 ︰, 1,7 ︰, 1,6 ︰, 1,5 ︰, 1,4 ︰, 1,3 ︰, 1,2 ︰, 1,1 ︰, 1,1 ︰, 2,1 ︰, 3,1 ︰, 4,1 ︰, 5,1 ︰, 6,1 ︰, 7,1 ︰, 8,1 ︰, 9,1 ︰ 10; Synergy ratio was maximum when wherein fluazinam and orysastrobin weight ratio were 2:1, and synergistic effect is the most obvious.
Application implementation example five:
Supply the examination disease: downy mildew of garpe, test medicine provides experimental scheme by Shaanxi agricultural chemicals Co., Ltd of U.S. nation: effective inhibition concentration scope of confirming the former medicine of fluazinam and fluoxastrobin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
The composite toxicity test analysis of results table of table 16 fluazinam and fluoxastrobin to downy mildew of garpe
Can know by table 16; The composite proportioning of preventing and treating downy mildew of garpe of fluazinam and fluoxastrobin is when 1 ︰, 60 ~ 80 ︰ 1; Synergy ratio SR is all greater than 1.5, explains that both are mixed all to show synergistic effect in 1 ︰, 60 ~ 80 ︰, 1 scope, and the proportioning of fluazinam and fluoxastrobin was at 1: 10～20: 1; Synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing the proportioning of finding fluazinam and fluoxastrobin through the applicant is 20 ︰, 1,15 ︰, 1,10 ︰, 1,9 ︰, 1,8 ︰, 1,7 ︰, 1,6 ︰, 1,5 ︰, 1,4 ︰, 1,3 ︰, 1,2 ︰, 1,1 ︰, 1,1 ︰, 2,1 ︰, 3,1 ︰, 4,1 ︰, 5,1 ︰, 6,1 ︰, 7,1 ︰, 8,1 ︰, 9,1 ︰ 10; Synergy ratio was maximum when wherein fluazinam and fluoxastrobin weight ratio were 2:1, and synergistic effect is the most obvious.
Application implementation example six:
Supply the examination disease: cucumber downy mildew, test medicine provides experimental scheme by Shaanxi agricultural chemicals Co., Ltd of U.S.A nation: pass through effective inhibition concentration scope that fluazinam and the former medicine of oxime bacterium ester and the two different proportioning mixture are confirmed in preliminary experiment.
The composite toxicity test analysis of results table of table 17 fluazinam and oxime bacterium ester to cucumber downy mildew
Can know by table 17; The proportioning of fluazinam and the composite control cucumber downy mildew of oxime bacterium ester is when 1 ︰, 60 ~ 80 ︰ 1; Synergy ratio SR is all greater than 1.5, explains that both are mixed all to show synergistic effect in 1 ︰, 60 ~ 80 ︰, 1 scope, and the proportioning of fluazinam and oxime bacterium ester was at 1: 10～20: 1; Synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing the proportioning of finding fluazinam and oxime bacterium ester through the applicant is 20 ︰, 1,15 ︰, 1,10 ︰, 1,9 ︰, 1,8 ︰, 1,7 ︰, 1,6 ︰, 1,5 ︰, 1,4 ︰, 1,3 ︰, 1,2 ︰, 1,1 ︰, 1,1 ︰, 2,1 ︰, 3,1 ︰, 4,1 ︰, 5,1 ︰, 6,1 ︰, 7,1 ︰, 8,1 ︰, 9,1 ︰ 10; Synergy ratio was maximum when wherein fluazinam and oxime bacterium ester weight ratio were 2:1, and synergistic effect is the most obvious.
Application implementation example seven:
Supply the examination disease: citrus anthracnose, test medicine provides experimental scheme by Shaanxi agricultural chemicals Co., Ltd of U.S. nation: effective inhibition concentration scope of confirming the former medicine of fluazinam and kresoxim-methyl and the two different proportioning mixture through preliminary experiment.
The composite toxicity test analysis of results table of table 18 fluazinam and kresoxim-methyl to citrus anthracnose
Can know by table 18; The proportioning of the composite control citrus anthracnose of fluazinam and kresoxim-methyl is when 1 ︰, 60 ~ 80 ︰ 1; Synergy ratio SR is all greater than 1.5, explains that both are mixed all to show synergistic effect in 1 ︰, 60 ~ 80 ︰, 1 scope, and the proportioning of fluazinam and kresoxim-methyl was at 1: 10～20: 1; Synergistic effect is more outstanding, and synergy ratio is all more than 2.20.Testing the proportioning of finding fluazinam and kresoxim-methyl through the applicant is 20 ︰, 1,15 ︰, 1,10 ︰, 1,9 ︰, 1,8 ︰, 1,7 ︰, 1,6 ︰, 1,5 ︰, 1,4 ︰, 1,3 ︰, 1,2 ︰, 1,1 ︰, 1,1 ︰, 2,1 ︰, 3,1 ︰, 4,1 ︰, 5,1 ︰, 6,1 ︰, 7,1 ︰, 8,1 ︰, 9,1 ︰ 10; Synergy ratio was maximum when wherein fluazinam and kresoxim-methyl weight ratio were 2:1, and synergistic effect is the most obvious.
Find through test: the control to common diseases such as the downy mildew on the various crop, peronospora tabacina, early blight, late blight, gray mold, powdery mildew, rice blast, damping off, rust, white rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthracnose, spot defoliation, spike rot, club root, stalk breaks after fluazinam and active component B are composite all has obvious synergistic effect, and co-toxicity coefficient is all more than 1.50.
Experimental section: test medicine is researched and developed, is provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 40% fluazinam suspending agent (commercial), 22% ZEN 90160 suspending agent (commercial), 10% SSF 126 suspending agent (autogamy), 20% orysastrobin suspending agent (autogamy), 20% fluoxastrobin suspending agent (autogamy), 20% oxime bacterium ester suspending agent (autogamy), 30% kresoxim-methyl suspending agent (commercial).
Application implementation example eight fluazinams and the active component B and the composite potato late blight test of pesticide effectiveness of preventing and treating thereof, this EE is Weinan City in Shaanxi Province, the investigation potato late blight state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 7 days, 15 days after the dispenser for the second time.Experimental result is as follows:
Table 19 fluazinam and active component B and the composite potato late blight test of pesticide effectiveness of preventing and treating thereof
Can find out by table 19, fluazinam and active component B and composite after can effectively prevent and treat potato late blight, control efficiency all is superior to the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application implementation example nine fluazinams and the active component B and the composite control gray mold of cucumber test of pesticide effectiveness thereof, this test arrangement are investigated the gray mold of cucumber state of an illness in the Jingyang County, Shaanxi Province before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 7 days, 15 days after the dispenser for the second time.Experimental result is as follows:
Table 20 fluazinam and active component B and the composite control gray mold of cucumber test of pesticide effectiveness thereof
Can find out by table 20, fluazinam and active component B and composite after can effectively prevent and treat gray mold of cucumber, control efficiency all is superior to the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application implementation example ten fluazinams and the active component B and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof; This test arrangement is Weinan City in Shaanxi Province, and the investigation alternaria leaf spot of apple state of an illness before the medicine is in the dispenser for the first time of state of an illness initial stage; Dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 21 fluazinam and active component B and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
Can find out by table 21, fluazinam and active component B and composite after can effectively prevent and treat alternaria leaf spot of apple, control efficiency all is superior to the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application implementation example 11 fluazinams and the active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof; This test arrangement is in Zengcheng City, Guangdong Province, and the investigation peronophythora litchi state of an illness before the medicine is in the dispenser for the first time of state of an illness initial stage; Dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 22 fluazinam and active component B and the composite control peronophythora litchi test of pesticide effectiveness thereof
Can find out by table 22, fluazinam and active component B and composite after can effectively prevent and treat peronophythora litchi, control efficiency all is superior to the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application implementation example 12 fluazinams and the active component B and the composite downy mildew of garpe test of pesticide effectiveness of preventing and treating thereof, this EE is Weinan City in Shaanxi Province, the investigation downy mildew of garpe state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 23 fluazinam and active component B and the composite downy mildew of garpe test of pesticide effectiveness of preventing and treating thereof
Can find out by table 23, fluazinam and active component B and composite after can effectively prevent and treat downy mildew of garpe, control efficiency all is superior to the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application implementation example 13 fluazinams and the active component B and the composite control Chinese cabbage club root test of pesticide effectiveness thereof, this test arrangement is Weinan City in Shaanxi Province, the investigation Chinese cabbage club root state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 7 days, 15 days after the dispenser for the second time.Experimental result is as follows:
Table 24 fluazinam and active component B and the composite control Chinese cabbage club root test of pesticide effectiveness thereof
Can find out by table 24, fluazinam and active component B and composite after can effectively prevent and treat the Chinese cabbage club root, control efficiency all is superior to the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application implementation example 14 fluazinams and the active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof, this test arrangement are investigated the cucumber downy mildew state of an illness in the Jingyang County, Shaanxi Province before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 7 days, 15 days after the dispenser for the second time.Experimental result is as follows:
Table 25 fluazinam and active component B and the composite control cucumber downy mildew test of pesticide effectiveness thereof
Can find out by table 25, fluazinam and active component B and composite after can effectively prevent and treat cucumber downy mildew, control efficiency all is superior to the preventive effect of single agent, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
After draw through not comprovincial test throughout the country; Fluazinam and ZEN 90160, SSF 126, orysastrobin, fluoxastrobin, oxime bacterium ester, the composite back of kresoxim-methyl to the preventive effect of common diseases such as the downy mildew on the various crop, peronospora tabacina, early blight, late blight, gray mold, powdery mildew, rice blast, damping off, rust, white rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthracnose, spot defoliation, spike rot, club root, stalk break all 95% with on excellent; In single agent preventive effect, synergistic effect is obvious.
Claims (6)
1. bactericidal composition that contains fluazinam and methoxy acrylic; It is characterized in that: contain active components A and active component B; Active components A and active component B weight ratio are 1: 60～80: 1; Described active components A is selected from fluazinam, and active component B is selected from a kind of in ZEN 90160, SSF 126, orysastrobin, fluoxastrobin, oxime bacterium ester, the kresoxim-methyl.
2. the bactericidal composition that contains fluazinam and methoxy acrylic according to claim 1 is characterized in that: the weight ratio of active components A and active component B is 1: 40～60: 1.
3. the bactericidal composition that contains fluazinam and methoxy acrylic according to claim 2 is characterized in that:
The weight ratio of fluazinam and ZEN 90160 is 1: 20～20: 1;
The weight ratio of fluazinam and SSF 126 is 1: 10～30: 1;
The weight ratio of fluazinam and orysastrobin is 1: 10～20: 1;
The weight ratio of fluazinam and fluoxastrobin is 1: 10～20: 1;
The weight ratio of fluazinam and oxime bacterium ester is 1: 10～20: 1;
The weight ratio of fluazinam and kresoxim-methyl is 1: 10～20: 1.
4. according to each described bactericidal composition that contains fluazinam and methoxy acrylic in the claim 1～3, it is characterized in that: composition is processed wetting powder, water dispersible granules, suspending agent, aqueous emulsion, microemulsion, suspension emulsion, microcapsule suspending agent, microcapsule suspension-suspending agent.
5. the bactericidal composition that contains fluazinam and methoxy acrylic according to claim 4 is used to prevent and treat the purposes of crop pest.
6. purposes according to claim 5 is characterized in that: described disease comprises downy mildew, peronospora tabacina, early blight, late blight, gray mold, powdery mildew, rice blast, damping off, rust, white rot, scab, glume blight, net blotch, leaf blight, brown spot, moire disease, anthracnose, spot defoliation, spike rot, stalk break, club root.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103210910A (en) * | 2013-03-24 | 2013-07-24 | 广东中迅农科股份有限公司 | Orysastrobin aqueous suspending agent and preparation method thereof |
| CN104115855A (en) * | 2013-04-25 | 2014-10-29 | 陕西美邦农药有限公司 | Efficient sterilization composition containing SYP-7017 |
| CN104604867A (en) * | 2013-11-05 | 2015-05-13 | 南京华洲药业有限公司 | Sterilization composition containing fluazinam and kresoxim methyl as well as application thereof |
| CN104604865A (en) * | 2013-11-05 | 2015-05-13 | 南京华洲药业有限公司 | Sterilization composition containing fluazinam and picoxystrobin, and applications thereof |
| CN106973924A (en) * | 2017-04-27 | 2017-07-25 | 广东广康生化科技股份有限公司 | Composition pesticide containing captan and fluazinam |
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| WO1998054965A1 (en) * | 1997-06-06 | 1998-12-10 | Basf Aktiengesellschaft | Fungicidal mixtures |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103210910A (en) * | 2013-03-24 | 2013-07-24 | 广东中迅农科股份有限公司 | Orysastrobin aqueous suspending agent and preparation method thereof |
| CN103210910B (en) * | 2013-03-24 | 2016-10-05 | 广东中迅农科股份有限公司 | Orysastrobin aqueous suspension agent and preparation method thereof |
| CN104115855A (en) * | 2013-04-25 | 2014-10-29 | 陕西美邦农药有限公司 | Efficient sterilization composition containing SYP-7017 |
| CN104115855B (en) * | 2013-04-25 | 2018-04-03 | 陕西美邦农药有限公司 | A kind of efficient bactericidal composite containing chlorine nalidixic bacterium ester |
| CN104604867A (en) * | 2013-11-05 | 2015-05-13 | 南京华洲药业有限公司 | Sterilization composition containing fluazinam and kresoxim methyl as well as application thereof |
| CN104604865A (en) * | 2013-11-05 | 2015-05-13 | 南京华洲药业有限公司 | Sterilization composition containing fluazinam and picoxystrobin, and applications thereof |
| CN106973924A (en) * | 2017-04-27 | 2017-07-25 | 广东广康生化科技股份有限公司 | Composition pesticide containing captan and fluazinam |
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