CN102686261B - 增强型的喷射器设计 - Google Patents

增强型的喷射器设计 Download PDF

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Publication number
CN102686261B
CN102686261B CN201080058137.2A CN201080058137A CN102686261B CN 102686261 B CN102686261 B CN 102686261B CN 201080058137 A CN201080058137 A CN 201080058137A CN 102686261 B CN102686261 B CN 102686261B
Authority
CN
China
Prior art keywords
injector
constriction
length
physical dimension
siphon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201080058137.2A
Other languages
English (en)
Chinese (zh)
Other versions
CN102686261A (zh
Inventor
B·斯特德曼
P·卡卡德
D·韦勒
J·伦纳德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MAP Pharmaceuticals Inc
Original Assignee
MAP Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MAP Pharmaceuticals Inc filed Critical MAP Pharmaceuticals Inc
Publication of CN102686261A publication Critical patent/CN102686261A/zh
Application granted granted Critical
Publication of CN102686261B publication Critical patent/CN102686261B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/30—Injector mixers
    • B01F25/31—Injector mixers in conduits or tubes through which the main component flows
    • B01F25/312—Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof
    • B01F25/3124—Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof characterised by the place of introduction of the main flow
    • B01F25/31242—Injector mixers in conduits or tubes through which the main component flows with Venturi elements; Details thereof characterised by the place of introduction of the main flow the main flow being injected in the central area of the venturi, creating an aspiration in the circumferential part of the conduit
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04F—PUMPING OF FLUID BY DIRECT CONTACT OF ANOTHER FLUID OR BY USING INERTIA OF FLUID TO BE PUMPED; SIPHONS
    • F04F5/00—Jet pumps, i.e. devices in which flow is induced by pressure drop caused by velocity of another fluid flow
    • F04F5/44—Component parts, details, or accessories not provided for in, or of interest apart from, groups F04F5/02 - F04F5/42
    • F04F5/46—Arrangements of nozzles
    • F04F5/463—Arrangements of nozzles with provisions for mixing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F15—FLUID-PRESSURE ACTUATORS; HYDRAULICS OR PNEUMATICS IN GENERAL
    • F15D—FLUID DYNAMICS, i.e. METHODS OR MEANS FOR INFLUENCING THE FLOW OF GASES OR LIQUIDS
    • F15D1/00—Influencing flow of fluids
    • F15D1/02—Influencing flow of fluids in pipes or conduits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0096—Hindering inhalation before activation of the dispenser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/20—Flow characteristics having means for promoting or enhancing the flow, actively or passively

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Jet Pumps And Other Pumps (AREA)
CN201080058137.2A 2009-12-23 2010-12-23 增强型的喷射器设计 Expired - Fee Related CN102686261B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28478409P 2009-12-23 2009-12-23
US61/284,784 2009-12-23
PCT/US2010/062084 WO2011079310A1 (en) 2009-12-23 2010-12-23 Enhanced eductor design

Publications (2)

Publication Number Publication Date
CN102686261A CN102686261A (zh) 2012-09-19
CN102686261B true CN102686261B (zh) 2014-09-10

Family

ID=44185936

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080058137.2A Expired - Fee Related CN102686261B (zh) 2009-12-23 2010-12-23 增强型的喷射器设计

Country Status (9)

Country Link
US (4) US9227030B2 (enExample)
EP (1) EP2515978B1 (enExample)
JP (3) JP5781540B2 (enExample)
CN (1) CN102686261B (enExample)
AU (1) AU2010336338B2 (enExample)
CA (1) CA2781313C (enExample)
IL (3) IL219744A (enExample)
IN (1) IN2012DN04857A (enExample)
WO (1) WO2011079310A1 (enExample)

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US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
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US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
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JP5781540B2 (ja) * 2009-12-23 2015-09-24 マップ・ファーマシューティカルズ・インコーポレイテッド 強化排出装置設計
IL223742A (en) * 2010-06-21 2016-06-30 Mannkind Corp A dry powder inhaler and preparation for it
EP2694402B1 (en) 2011-04-01 2017-03-22 MannKind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
HK1200318A1 (en) 2011-10-24 2015-08-07 曼金德公司 Methods and compositions for treating pain
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CN104582771B (zh) 2012-08-29 2018-09-04 奇斯药制品公司 气溶胶吸入装置
WO2014140724A1 (en) * 2013-03-14 2014-09-18 Trudell Medical International Metered dose inhaler applicator
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GB201308679D0 (en) * 2013-05-14 2013-06-26 3M Innovative Properties Co Actuator for an inhaler
KR102465025B1 (ko) 2013-07-18 2022-11-09 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
CN103877655B (zh) * 2014-04-08 2015-12-30 隋宁昕 自吸固定式吸氧鼻塞
US11291780B2 (en) * 2014-12-04 2022-04-05 Vyaire Medical Consumables Llc Breath-actuated nebulizer for medicine inhalation
CN108697868B (zh) * 2015-12-21 2021-09-21 3M创新有限公司 药用吸入器
GB201702407D0 (en) * 2017-02-14 2017-03-29 Norton (Waterford) Ltd Inhalers and related methods
GB201707095D0 (en) 2017-05-04 2017-06-21 3M Innovative Properties Co Inhaler flow control mechanism
CN109210374B (zh) * 2017-06-30 2021-06-08 北京北方华创微电子装备有限公司 进气管路及半导体加工设备
EP3758772B1 (en) * 2018-04-06 2024-10-09 Frank Levy Apparatus for producing an enriched medical suspension
CN110433366B (zh) * 2019-08-12 2022-03-04 杭州市红十字会医院 一种便携式呼吸科给药器
CN113898570B (zh) * 2021-12-08 2022-02-08 常州萨柏美格医用气体设备有限公司 气体流动过程检测装置及方法、空气压缩机组及检测方法
CN114798201B (zh) * 2022-06-29 2022-10-04 山东沃德净水科技有限公司 一种喷射器优化方法及喷射器
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US5826570A (en) * 1991-03-05 1998-10-27 Aradigm Corporation Delivery of aerosol medications for inspiration
US5740794A (en) * 1994-09-21 1998-04-21 Inhale Therapeutic Systems Apparatus and methods for dispersing dry powder medicaments
CN1255869A (zh) * 1998-02-06 2000-06-07 日商优尼希雅·杰克斯股份有限公司 药物吸入器
US20040011357A1 (en) * 2000-07-05 2004-01-22 Philip Braithwaite Actuator comprising moveable membrane
CN101410189A (zh) * 2006-03-27 2009-04-15 贝林格尔英格海姆法玛两合公司 用以施用药物制剂的剂量喷雾器

Also Published As

Publication number Publication date
IN2012DN04857A (enExample) 2015-09-25
US9610415B2 (en) 2017-04-04
US9227030B2 (en) 2016-01-05
JP2015221225A (ja) 2015-12-10
US20200030555A1 (en) 2020-01-30
CA2781313A1 (en) 2011-06-30
JP5781540B2 (ja) 2015-09-24
EP2515978A1 (en) 2012-10-31
AU2010336338A1 (en) 2012-06-21
US20110155129A1 (en) 2011-06-30
CN102686261A (zh) 2012-09-19
EP2515978A4 (en) 2015-03-04
CA2781313C (en) 2019-09-17
US20160129208A1 (en) 2016-05-12
IL242205A (en) 2017-07-31
AU2010336338B2 (en) 2015-02-19
IL252847A0 (en) 2017-08-31
JP2017164554A (ja) 2017-09-21
JP2013515577A (ja) 2013-05-09
WO2011079310A1 (en) 2011-06-30
IL242205A0 (en) 2015-11-30
IL219744A0 (en) 2012-07-31
IL252847B (en) 2021-02-28
JP6157542B2 (ja) 2017-07-05
EP2515978B1 (en) 2018-02-14
US20170056609A1 (en) 2017-03-02
IL219744A (en) 2015-11-30

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Granted publication date: 20140910