CN102671128B - Drug for treating arteriosclerosis - Google Patents

Drug for treating arteriosclerosis Download PDF

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CN102671128B
CN102671128B CN2012101543203A CN201210154320A CN102671128B CN 102671128 B CN102671128 B CN 102671128B CN 2012101543203 A CN2012101543203 A CN 2012101543203A CN 201210154320 A CN201210154320 A CN 201210154320A CN 102671128 B CN102671128 B CN 102671128B
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rhizoma
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radix
fructus
curcumae
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CN102671128A (en
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张霞
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Wang Jing
Yu Jikui
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Abstract

The invention provides a drug for treating arteriosclerosis, which is prepared by the following traditional Chinese medicines of: white peony, hawthorn, cherokee rose fruit, Codonopsis pilosula, lophatherum gracile, rhizoma atractylodis, silkworm larva, Polygonum cuspidatum, semen cassia, rhizoma alismatis, radix bupleuri, radix curcumae, fruit of Chinese wolfberry, Poria cocos, plantain seed, white atractylodes rhizome, Manis pentadactyla, gastrodia elata, Ligusticum wallichii, trigone, zedoary, leech, Polygonum multiflorum, frankincense, myrrh and oyster. The drug provided by the invention has better treatment effects on the common symptoms of the patients with arteriosclerosis, such as palpitation, flustering, chest pain, choking sensation in chest, headache, dizziness, cold and numb extremities, soreness and weakness of limbs, claudication, blurred vision, poor memory, insomnia and dreaminess, and also has better preventive effect on the city dwellers, the person who engages in intense brain works, the obese person, the heavy smoking person, the patient with hypertension, the patient with diabetes mellitus, the patient with hyperlipemia and the population susceptible to the arteriosclerosis; and the drug has the outstanding effects of no toxic or side effects, no untoward effect, and high cure rate.

Description

A kind ofly treat arteriosclerotic medicine
1, technical field
The present invention relates to a kind of Chinese medicine preparation, specifically a kind ofly treat arteriosclerotic medicine.
2, background technology
Arteriosclerosis is a kind of non-inflammation pathological changes of tremulous pulse, can make that ductus arteriosus wall thickens, hardening, follows the string, official jargon is narrow and small.Arteriosclerosis is with age and the angiopathy that occurs, and its rule normally occurs at adolescence, increases the weight of period, falls ill to person in middle and old age.Now Therapeutic Method comparatively commonly used is the therapy of oral drugs, has a medical expense high, has the problem of side effect.
This disease has the characteristics such as large to human health damage, that sickness rate is high, the course of disease is long, to patient, has brought great misery, and existing medicine can only alleviate patient's misery and remove patient's clinical manifestation and can not eradicate the purpose that this disease reaches healing.
3, summary of the invention
The purpose of this invention is to provide a kind of therapeutic effect good, be free from side effects can realize treating both the principal and secondary aspects of a disease a kind ofly treat arteriosclerotic medicine.
The present invention is according to the Chinese medicine traditional theory, and selected have an activating blood circulation to dissipate blood stasis, and nourishing the liver and kidney improves the pure Chinese herbal medicine of immunologic function, can eradicate arteriosclerotic disease, realize treating both the principal and secondary aspects of a disease, and this medicine is easy to prepare, take rear instant effect, have no side effect, have no adverse reaction after taking medicine.
It is of the present invention that a kind of to treat arteriosclerotic medicine be to be made by the crude drug of following weight ratio:
Radix Paeoniae Alba 5-15 part, Fructus Crataegi 20-40 part, Fructus Rosae Laevigatae 5-15 part, Radix Codonopsis 3-8 part,
Herba Lophatheri 3-10 part, Rhizoma Atractylodis 5-12 part, Bombyx Batryticatus 3-8 part, Rhizoma Polygoni Cuspidati 5-15 part,
Semen Cassiae 10-20 part, Rhizoma Alismatis 3-8 part, Radix Bupleuri 5-15 part, Radix Curcumae 3-10 part,
Fructus Lycii 10-20 part, Poria 5-12 part, Semen Plantaginis 8-15 part, Rhizoma Atractylodis Macrocephalae 3-10 part,
Squama Manis 3-8 part, Rhizoma Gastrodiae 5-15 part, Rhizoma Chuanxiong 3-10 part, Rhizoma Sparganii 3-5 part,
Rhizoma Curcumae 3-5 part, Hirudo 5-8 part, Radix Polygoni Multiflori 5-15 part, Olibanum 3-10 part,
Myrrha 5-15 part, Concha Ostreae 3-8 part;
Preparation process is as follows:
Take in proportion Radix Paeoniae Alba, Fructus Crataegi, Fructus Rosae Laevigatae, Radix Codonopsis, Herba Lophatheri, Rhizoma Atractylodis, Bombyx Batryticatus, Rhizoma Polygoni Cuspidati, Semen Cassiae, Rhizoma Alismatis, Radix Bupleuri, Radix Curcumae, Fructus Lycii, Poria, Semen Plantaginis, the Rhizoma Atractylodis Macrocephalae, Squama Manis, Rhizoma Gastrodiae, Rhizoma Chuanxiong, Rhizoma Sparganii, Rhizoma Curcumae, Hirudo, Radix Polygoni Multiflori, Olibanum, each herbal medicine of Myrrha and Concha Ostreae, remove respectively impurity, dry parching to brown, by medicament mixed, the clear water that adds four times of amount medicines soaks 3 hours, in the immigration marmite, big fire is to boiling, then slow fire boiling is 3 hours, leach medicinal liquid, the clear water that adds again the qdx medicine continues to decoct 2 hours, getting supernatant send vaporizer the concentrated extractum of making, extractum is sent in drying baker and is dried at 130 ℃ of temperature, be ground into 300 order smalls, after sterilization, by the 0.5g/ grain, incapsulate, be finished product.
Also can make the said oral liquid of pharmaceutics by pharmaceutical technologies such as traditional coarse crushing, immersion, heating extraction.
It is of the present invention that a kind of to treat arteriosclerotic medicine be to be made by the crude drug of following weight ratio:
Radix Paeoniae Alba 8-12 part, Fructus Crataegi 25-35 part, Fructus Rosae Laevigatae 8-12 part, Radix Codonopsis 4-6 part,
Herba Lophatheri 5-8 part, Rhizoma Atractylodis 8-10 part, Bombyx Batryticatus 4-6 part, Rhizoma Polygoni Cuspidati 8-12 part,
Semen Cassiae 12-18 part, Rhizoma Alismatis 4-6 part, Radix Bupleuri 8-12 part, Radix Curcumae 5-8 part,
Fructus Lycii 12-18 part, Poria 6-10 part, Semen Plantaginis 10-14 part, Rhizoma Atractylodis Macrocephalae 5-8 part,
Squama Manis 4-6 part, Rhizoma Gastrodiae 8-12 part, Rhizoma Chuanxiong 5-8 part, Rhizoma Sparganii 3.5-4.5 part,
Rhizoma Curcumae 3.5-4.5 part, Hirudo 5-7 part, Radix Polygoni Multiflori 8-12 part, Olibanum 5-8 part,
Myrrha 8-12 part, Concha Ostreae 4-6 part.
It is of the present invention that a kind of to treat arteriosclerotic medicine be to be made by the crude drug of following weight ratio:
10 parts of Radix Paeoniae Alba, 30 parts of Fructus Crataegis, 10 parts of Fructus Rosae Laevigatae, 5 parts of Radix Codonopsis,
6 parts of Herba Lophatheris, 9 parts of Rhizoma Atractylodis, 5 parts of Bombyx Batryticatus, 10 parts of Rhizoma Polygoni Cuspidati,
15 parts of Semen Cassiaes, 5 parts of Rhizoma Alismatis, 10 parts of Radix Bupleuri, 6 parts of Radix Curcumaes,
15 parts of Fructus Lycii, 8 parts, Poria, 12 parts of Semen Plantaginiss, 6 parts of the Rhizoma Atractylodis Macrocephalaes,
5 parts of Squama Maniss, 10 parts, Rhizoma Gastrodiae, 6 parts of Rhizoma Chuanxiongs, 4 parts of Rhizoma Sparganii,
4 parts of Rhizoma Curcumae, 6 parts of Hirudos, 10 parts of Radix Polygoni Multiflori, 6 parts of Olibanums,
10 parts of Myrrhas, 5 parts of Concha Ostreaes.
The common sympton that the present invention occurs the arteriosclerosis patient is as listless and aching as cardiopalmus, nervous, chest pain, uncomfortable in chest, headache, dizziness, the cool fiber crops of extremity, extremity, limping, vision reduction, hypomnesis, insomnia, dreaminess etc. have good therapeutic effect, for the urbanite, be engaged in nervous brain worker, obesity, have a liking for cigarette, hypertension, diabetes, hyperlipemia is suffered from and easily suffer from this sick crowd that good preventive effect is also arranged, the outstanding effect of this medicine is to have no side effect, have no adverse reaction, radical cure efficiency is high.
The specific embodiment
Embodiment 1
Radix Paeoniae Alba 5g, Fructus Crataegi 20g, Fructus Rosae Laevigatae 5g, Radix Codonopsis 3g,
Herba Lophatheri 3g, Rhizoma Atractylodis 5g, Bombyx Batryticatus 3g, Rhizoma Polygoni Cuspidati 5g,
Semen Cassiae 10g, Rhizoma Alismatis 3g, Radix Bupleuri 5g, Radix Curcumae 3g,
Fructus Lycii 10g, Poria 5g, Semen Plantaginis 8g, Rhizoma Atractylodis Macrocephalae 3g,
Squama Manis 3g, Rhizoma Gastrodiae 5g, Rhizoma Chuanxiong 3g, Rhizoma Sparganii 3g,
Rhizoma Curcumae 3g, Hirudo 5g, Radix Polygoni Multiflori 5g, Olibanum 3g,
Myrrha 5g, Concha Ostreae 3g;
Preparation process is as follows:
Take in proportion Radix Paeoniae Alba, Fructus Crataegi, Fructus Rosae Laevigatae, Radix Codonopsis, Herba Lophatheri, Rhizoma Atractylodis, Bombyx Batryticatus, Rhizoma Polygoni Cuspidati, Semen Cassiae, Rhizoma Alismatis, Radix Bupleuri, Radix Curcumae, Fructus Lycii, Poria, Semen Plantaginis, the Rhizoma Atractylodis Macrocephalae, Squama Manis, Rhizoma Gastrodiae, Rhizoma Chuanxiong, Rhizoma Sparganii, Rhizoma Curcumae, Hirudo, Radix Polygoni Multiflori, Olibanum, each herbal medicine of Myrrha and Concha Ostreae, remove respectively impurity, dry parching to brown, by medicament mixed, the clear water that adds four times of amount medicines soaks 3 hours, in the immigration marmite, big fire is to boiling, then slow fire boiling is 3 hours, leach medicinal liquid, the clear water that adds again the qdx medicine continues to decoct 2 hours, getting supernatant send vaporizer the concentrated extractum of making, extractum is sent in drying baker and is dried at 130 ℃ of temperature, be ground into 300 order smalls, after sterilization, by the 0.5g/ grain, incapsulate, be finished product.
Embodiment 2
Radix Paeoniae Alba 15g, Fructus Crataegi 40g, Fructus Rosae Laevigatae 15g, Radix Codonopsis 8g,
Herba Lophatheri 10g, Rhizoma Atractylodis 12g, Bombyx Batryticatus 8g, Rhizoma Polygoni Cuspidati 15g,
Semen Cassiae 20g, Rhizoma Alismatis 8g, Radix Bupleuri 15g, Radix Curcumae 10g,
Fructus Lycii 20g, Poria 12g, Semen Plantaginis 15g, Rhizoma Atractylodis Macrocephalae 10g,
Squama Manis 8g, Rhizoma Gastrodiae 15g, Rhizoma Chuanxiong 10g, Rhizoma Sparganii 5g,
Rhizoma Curcumae 5g, Hirudo 8g, Radix Polygoni Multiflori 15g, Olibanum 10g,
Myrrha 15g, Concha Ostreae 8g.
Preparation process is identical with embodiment 1.
Embodiment 3
Radix Paeoniae Alba 8g, Fructus Crataegi 25g, Fructus Rosae Laevigatae 8g, Radix Codonopsis 4g,
Herba Lophatheri 5g, Rhizoma Atractylodis 8g, Bombyx Batryticatus 4g, Rhizoma Polygoni Cuspidati 8g,
Semen Cassiae 12g, Rhizoma Alismatis 4g, Radix Bupleuri 8g, Radix Curcumae 5g,
Fructus Lycii 12g, Poria 6g, Semen Plantaginis 10g, Rhizoma Atractylodis Macrocephalae 5g,
Squama Manis 4g, Rhizoma Gastrodiae 8g, Rhizoma Chuanxiong 5g, Rhizoma Sparganii 3.5g,
Rhizoma Curcumae 3.5g, Hirudo 5g, Radix Polygoni Multiflori 8g, Olibanum 5g,
Myrrha 8g, Concha Ostreae 4g.
Preparation process is identical with embodiment 1.
Embodiment 4
Radix Paeoniae Alba 12g, Fructus Crataegi 35g, Fructus Rosae Laevigatae 12g, Radix Codonopsis 6g,
Herba Lophatheri 8g, Rhizoma Atractylodis 10g, Bombyx Batryticatus 6g, Rhizoma Polygoni Cuspidati 12g,
Semen Cassiae 18g, Rhizoma Alismatis 6g, Radix Bupleuri 12g, Radix Curcumae 8g,
Fructus Lycii 18g, Poria 10g, Semen Plantaginis 14g, Rhizoma Atractylodis Macrocephalae 8g,
Squama Manis 6g, Rhizoma Gastrodiae 12g, Rhizoma Chuanxiong 8g, Rhizoma Sparganii 4.5g,
Rhizoma Curcumae 4.5g, Hirudo 7g, Radix Polygoni Multiflori 12g, Olibanum 8g,
Myrrha 12g, Concha Ostreae 6g.
Preparation process is identical with embodiment 1.
Embodiment 5
Radix Paeoniae Alba 10g, Fructus Crataegi 30g, Fructus Rosae Laevigatae 10g, Radix Codonopsis 5g,
Herba Lophatheri 6g, Rhizoma Atractylodis 9g, Bombyx Batryticatus 5g, Rhizoma Polygoni Cuspidati 10g,
Semen Cassiae 15g, Rhizoma Alismatis 5g, Radix Bupleuri 10g, Radix Curcumae 6g,
Fructus Lycii 15g, Poria 8g, Semen Plantaginis 12g, Rhizoma Atractylodis Macrocephalae 6g,
Squama Manis 5g, Rhizoma Gastrodiae 10g, Rhizoma Chuanxiong 6g, Rhizoma Sparganii 4g,
Rhizoma Curcumae 4g, Hirudo 6g, Radix Polygoni Multiflori 10g, Olibanum 6g,
Myrrha 10g, Concha Ostreae 5g.
Preparation process is identical with embodiment 1.
Model case: in the 100 routine patients through curing with this prescription, male 65 examples wherein, female's 35 examples are the course of disease the shortest half a year, the longest 10 years.
Efficacy determination: adopt 4 grade standards
Recovery from illness clinical improvements rate >=95%
Produce effects clinical improvements rate<95%,
Effective clinical improvement rate<60%,
Invalid clinical improvements rate<20%
Therapeutic effect statistics in Table
Figure BSA00000718941400051
It is 88% that the present invention treats arteriosclerotic Drug therapy cure rate, and effectively cure rate is 97%.
The typical clinical case:
Case 1, Zhang, man 70 years old, be diagnosed as arteriosclerosis in city hospital, show as dizzy dizzy headache, memory obviously goes down, take multiple Chinese medicine and western medicine effect all not obvious, took this medicine before 2 years, every day twice, take dizzy headache shape after three weeks and alleviate, continue to take all symptoms after two weeks and substantially disappear, immunity also strengthens to some extent.
Case 2, field so-and-so, female 62 years old, clinical manifestation is that two sufficient pain can not be walked, can only lie up and can not get up at ordinary times, be diagnosed as arteriosclerosis, take upon somebody's introduction this medicine, take twice of this medicine every day, taken continuously after three weeks and can descend bed motion once in a while under others assisting in, it is many that whole body is also comfortable, after continuing to have taken three weeks, can oneself leave the bed and simply move, whole body also energetically, the symptom recovery from illness, patient and family members thereof are very satisfied.
Case 3, Lin, female 67 years old, clinical manifestation is hand tremor, hands acroanesthesia, easy tired, hypomnesis, by hospital diagnosis, be arteriosclerosis, take this medicine every day twice, the phenomenon of having taken continuously numbness of hand hand tremor after two weeks takes a turn for the better to some extent, continue to take two weeks afterwards clinical manifestation completely without, the disease recovery from illness, immunity also strengthens to some extent.
Case 4, Lee, man 62 years old, clinical manifestation is, dizziness, accidental angina pectoris, whole body discomfort is the several years, red tongue, tongue is few, stringy and thready pulse, be diagnosed as arteriosclerosis through hospital, renal arteriosclerosis, take this medicine twice on the one, dizzy after two weeks, anginal frequency reduces to some extent, and whole body sense of discomfort alleviates to some extent, continue to take this medicine after three weeks, clinical symptoms is completely without the recovery from illness of, the state of an illness.
Case 5, king so-and-so, man 70 years old, the health paralysis, inactive, be diagnosed as arteriosclerosis through hospital, taking twice, two week on the one rear health of this medicine slightly has consciousness, can do simple motion after adding three weeks under others' treatment, continue to take this medicine after six weeks, the control that the state of an illness is basic, I am satisfied.
Case 6, the side certain, man 45 years old, clinical presentation is, the degradation performance is obviously descended in dizzy, dizzy, poor memory, thinking, through hospital, is diagnosed as arteriosclerosis, takes upon somebody's introduction twice of this medicine every day, sx↓ after two weeks, continue to take recovery from illness after two weeks, so far not recurrence.

Claims (3)

1. treat arteriosclerotic medicine for one kind, it is characterized in that being made by the crude drug of following weight proportion:
Radix Paeoniae Alba 5-15 part, Fructus Crataegi 20-40 part, Fructus Rosae Laevigatae 5-15 part, Radix Codonopsis 3-8 part,
Herba Lophatheri 3-10 part, Rhizoma Atractylodis 5-12 part, Bombyx Batryticatus 3-8 part, Rhizoma Polygoni Cuspidati 5-15 part,
Semen Cassiae 10-20 part, Rhizoma Alismatis 3-8 part, Radix Bupleuri 5-15 part, Radix Curcumae 3-10 part,
Fructus Lycii 10-20 part, Poria 5-12 part, Semen Plantaginis 8-15 part, Rhizoma Atractylodis Macrocephalae 3-10 part,
Squama Manis 3-8 part, Rhizoma Gastrodiae 5-15 part, Rhizoma Chuanxiong 3-10 part, Rhizoma Sparganii 3-5 part,
Rhizoma Curcumae 3-5 part, Hirudo 5-8 part, Radix Polygoni Multiflori 5-15 part, Olibanum 3-10 part,
Myrrha 5-15 part, Concha Ostreae 3-8 part;
Preparation process is as follows:
Take in proportion Radix Paeoniae Alba, Fructus Crataegi, Fructus Rosae Laevigatae, Radix Codonopsis, Herba Lophatheri, Rhizoma Atractylodis, Bombyx Batryticatus, Rhizoma Polygoni Cuspidati, Semen Cassiae, Rhizoma Alismatis, Radix Bupleuri, Radix Curcumae, Fructus Lycii, Poria, Semen Plantaginis, the Rhizoma Atractylodis Macrocephalae, Squama Manis, Rhizoma Gastrodiae, Rhizoma Chuanxiong, Rhizoma Sparganii, Rhizoma Curcumae, Hirudo, Radix Polygoni Multiflori, Olibanum, each herbal medicine of Myrrha and Concha Ostreae, remove respectively impurity, dry parching to brown, by medicament mixed, the clear water that adds four times of amount medicines soaks 3 hours, in the immigration marmite, big fire is to boiling, then slow fire boiling is 3 hours, leach medicinal liquid, the clear water that adds again the qdx medicine continues to decoct 2 hours, getting supernatant send vaporizer the concentrated extractum of making, extractum is sent in drying baker and is dried at 130 ℃ of temperature, be ground into 300 order smalls, after sterilization, by the 0.5g/ grain, incapsulate, be finished product.
2. a kind of arteriosclerotic medicine for the treatment of according to claim 1 is characterized in that being made by the crude drug of following weight proportion:
Radix Paeoniae Alba 8-12 part, Fructus Crataegi 25-35 part, Fructus Rosae Laevigatae 8-12 part, Radix Codonopsis 4-6 part,
Herba Lophatheri 5-8 part, Rhizoma Atractylodis 8-10 part, Bombyx Batryticatus 4-6 part, Rhizoma Polygoni Cuspidati 8-12 part,
Semen Cassiae 12-18 part, Rhizoma Alismatis 4-6 part, Radix Bupleuri 8-12 part, Radix Curcumae 5-8 part,
Fructus Lycii 12-18 part, Poria 6-10 part, Semen Plantaginis 10-14 part, Rhizoma Atractylodis Macrocephalae 5-8 part,
Squama Manis 4-6 part, Rhizoma Gastrodiae 8-12 part, Rhizoma Chuanxiong 5-8 part, Rhizoma Sparganii 3.5-4.5 part,
Rhizoma Curcumae 3.5-4.5 part, Hirudo 5-7 part, Radix Polygoni Multiflori 8-12 part, Olibanum 5-8 part,
Myrrha 8-12 part, Concha Ostreae 4-6 part.
3. a kind of arteriosclerotic medicine for the treatment of according to claim 1 is characterized in that being made by the crude drug of following weight proportion:
10 parts of Radix Paeoniae Alba, 30 parts of Fructus Crataegis, 10 parts of Fructus Rosae Laevigatae, 5 parts of Radix Codonopsis,
6 parts of Herba Lophatheris, 9 parts of Rhizoma Atractylodis, 5 parts of Bombyx Batryticatus, 10 parts of Rhizoma Polygoni Cuspidati,
15 parts of Semen Cassiaes, 5 parts of Rhizoma Alismatis, 10 parts of Radix Bupleuri, 6 parts of Radix Curcumaes,
15 parts of Fructus Lycii, 8 parts, Poria, 12 parts of Semen Plantaginiss, 6 parts of the Rhizoma Atractylodis Macrocephalaes,
5 parts of Squama Maniss, 10 parts, Rhizoma Gastrodiae, 6 parts of Rhizoma Chuanxiongs, 4 parts of Rhizoma Sparganii,
4 parts of Rhizoma Curcumae, 6 parts of Hirudos, 10 parts of Radix Polygoni Multiflori, 6 parts of Olibanums,
10 parts of Myrrhas, 5 parts of Concha Ostreaes.
CN2012101543203A 2012-05-18 2012-05-18 Drug for treating arteriosclerosis Expired - Fee Related CN102671128B (en)

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CN103656495B (en) * 2013-11-26 2016-01-06 张雅静 Salvia miltiorrhiza phytic acid electuary
CN109876113A (en) * 2019-03-27 2019-06-14 苏凤哲 A kind of Chinese medicine composition and its preparation method and application for treating carotid plaques
CN113304235B (en) 2020-02-26 2022-07-26 北京重生医药科技有限公司 Traditional Chinese medicine composition and preparation method and application thereof

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CN101461900A (en) * 2007-12-17 2009-06-24 吴伶 Pure medicinal formulation for treating arteriosclerosis

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Publication number Priority date Publication date Assignee Title
CN101461900A (en) * 2007-12-17 2009-06-24 吴伶 Pure medicinal formulation for treating arteriosclerosis

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Title
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