CN102671036B - 治疗慢性肺脓肿中药口服液及制备方法 - Google Patents
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Abstract
本发明公开了一种治疗慢性肺脓肿中药口服液，是由下列重量份数的原料药制成的：白芨98-210份、黄连98-210份、黄芩98-210份、桔梗70-140份、芦根98-210份、甘草10-20份，本中药口服液特点是能使患者痊愈，效果好，毒副作用小，起到标本兼治、扶正不滞邪、祛邪不伤正的作用，无复发，成本低，值得临床推广应用。
Description
技术领域
本发明属于中药领域，特别涉及一种治疗慢性肺脓肿中药口服液及制备方法。
背景技术
肺脓肿(1ung abscess)是多种病原菌感染引起的肺组织化脓性炎症，导致组织坏死、破坏、液化形成脓肿。临床上以高热、咳嗽、咳大量脓臭痰，X线显示含气液平的空洞为特征。常见病原体包括金黄色葡萄球菌、化脓性链球菌、肺炎克雷白杆菌和铜绿假单胞菌等。中医药用于治疗慢性肺脓肿的药物，由于具有副作用小、疗效好的特点，故很受人们青睐。
发明内容
本发明的目的在于提供了一种副作用小、疗效好，用于治疗慢性肺脓肿中药口服液及制备方法。
为实现上述目的，本发明是通过以下技术方案实现的：
治疗慢性肺脓肿中药口服液，是由下列重量份数的原料药制成的：
白芨98-210份、黄连98-210份、黄芩98-210份、桔梗70-140份、芦根98-210份、甘草10-20份。
所述的治疗慢性肺脓肿中药口服液，是由下列重量份数的原料药制成的：
白芨210份、黄连210份、黄芩210份、桔梗140、芦根210份、甘草20份。
所述的治疗慢性肺脓肿中药口服液及制备方法，包括下列步骤：
取药材白芨210份、黄连210份、黄芩210份、桔梗140、芦根210份、甘草20份，用水煎煮二次，每次用水量为药材重量的8-10倍量，煎煮二次，每次1-2小时，滤过，滤液浓缩成在60-65℃测相对密度为1．10-1．25的清膏，加乙醇至使含乙醇量为60％，搅匀，静置，滤过，取滤液回收乙醇，浓缩成含固体重量65-67％的浸膏，加入蔗糖20％、炼蜜12％、防腐剂1-3％，原液灌封，辐照灭菌，包装成品，制成口服液，即得。
服用方法：每天早、中、晚各服用一次，一次用量15ml，1周为1个疗程。服药后多在1周见效，3-6个疗程治愈。本中药口服液特点是能使患者痊愈，效果好，毒副作用小，起到标本兼治、扶正不滞邪、祛邪不伤正的作用，无复发，成本低，值得临床推广应用。
本发明所选用的中药原料中，白芨：苦、甘、涩、微寒，归肺、肝、胃经，收敛止血、消肿生肌；黄连：苦、寒，归心、胃、肝、大肠经，清热燥湿、泻火解毒；黄芩：苦、寒，归肺、胆、胃、大肠经，清热燥湿、泻火解毒、止血、安胎；桔梗：苦、辛、平，归肺经，宣肺、利咽、祛痰、排脓；芦根：甘、寒，归肺、胃经，清热生津、止呕、利尿；甘草：甘、平，归心、脾、肺、胃经，补脾益气、润肺止咳、清热解毒、缓解止痛、缓和药性；诸药共奏亲热泻火、燥湿解毒之功。本发明口服液可迅速解除慢性肺脓肿所致的畏寒、发热、咳嗽、咳粘液痰或粘液脓痰的症状，专药专治，疗效显著。注意事项：孕妇禁用。
具体实施方式
实施例1：
原料药：白芨210份、黄连210份、黄芩210份、桔梗140、芦根210份、甘草20份。
制法：取药材白芨210份、黄连210份、黄芩210份、桔梗140、芦根210份、甘草20份，用水煎煮二次，每次用水量为药材重量的8-10倍量，煎煮二次，每次1-2小时，滤过，滤液浓缩成在60-65℃测相对密度为1．10-1．25的清膏，加乙醇至使含乙醇量为60％，搅匀，静置，滤过，取滤液回收乙醇，浓缩成含固体重量65-67％的浸膏，加入蔗糖20％、炼蜜12％、防腐剂1-3％，原液灌封，辐照灭菌，包装成品，制成口服液，即得。
实施例2：
原料药：白芨154份、黄连154份、黄芩154份、桔梗105份、芦根154份、甘草15份。
制法：取药材白芨154份、黄连154份、黄芩154份、桔梗105份、芦根154份、甘草15份，用水煎煮二次，每次用水量为药材重量的8-10倍量，煎煮二次，每次1-2小时，滤过，滤液浓缩成在60-65℃测相对密度为1．10-1．25的清膏，加乙醇至使含乙醇量为60％，搅匀，静置，滤过，取滤液回收乙醇，浓缩成含固体重量65-67％的浸膏，加入蔗糖20％、炼蜜12％、防腐剂1-3％，原液灌封，辐照灭菌，包装成品，制成口服液，即得。
实施例3：
原料药：白芨98份、黄连98份、黄芩98份、桔梗70份、芦根98份、甘草10份。
制法：取白芨98份、黄连98份、黄芩98份、桔梗70份、芦根98份、甘草10份，用水煎煮二次，每次用水量为药材重量的8-10倍量，煎煮二次，每次1-2小时，滤过，滤液浓缩成在60-65℃测相对密度为1．10-1．25的清膏，加乙醇至使含乙醇量为60％，搅匀，静置，滤过，取滤液回收乙醇，浓缩成含固体重量65-67％的浸膏，加入蔗糖20％、炼蜜12％、防腐剂1-3％，原液灌封，辐照灭菌，包装成品，制成口服液，即得。
实施例4：
(1)临床观察：对32例慢性肺脓肿患者进行临床治疗观察，年龄18到70岁，平均年龄63岁，病程2～5年。患者症状畏寒、发热，体温可高达39～40℃。伴咳嗽、咳粘液痰或粘液脓痰。炎症波及局部胸膜可引起胸痛。病变范围较大，可出现气急。此外，还有精神不振、乏力、胃纳差。约7～10天后，咳嗽加剧，脓肿破溃于支气管，咳出大量脓臭痰。
(2)治疗方法：用实施例1所制中药口服液，每天早、中、晚各服用一次，一次用量15ml，1周为1个疗程，2个疗程后观察疗效。
(3)疗效标准：
痊愈：喘息消失，无黏脓痰，胸痛消失；
显效：喘息明显减轻，咳痰量明显减少，胸痛减少；
有效：咳嗽减轻，痰量减少，胸痛减轻，呼吸困难减轻；
无效：上述症状无改善。
(4)治疗结果：服药后多在1周见效，3-6个疗程痊愈，临床治疗32例，其中治愈25例，显效3例，有效3例，无效1例，总有效率为96.8％。
实施例5：
典型病例：黎某，男，60岁，患慢性肺脓肿半年，症状发热，咯血，胸痛，咳嗽，服用本发明2周，病人喘息消失、咳痰减轻，又经一个月治疗后痊愈。
实施例6：
典型病例：翁某，男，65岁，患慢性肺脓肿2年，终日哮喘不止，咳出大量脓臭痰，精神不振、乏力、胃纳差，服用本发明2周即好转，又经一个月治疗，身体逐渐康复，呼吸、饮食、活动都有明显改善。
实施例7：
典型病例：吴某，女，45岁，患慢性肺脓肿半年，咳嗽，痰中带血，大便干结，服用本发明2周，阵咳平息，大便顺畅，喘息不得平卧的顽症得到缓解，再服用4周后痊愈。
Claims (1)
1.一种治疗慢性肺脓肿中药口服液的制备方法，其特征在于：包括下列步骤：
取药材白芨98份、黄连98份、黄芩98份、桔梗70份、芦根98份、甘草10份，用水煎煮二次，每次用水量为药材重量的8-10倍量，每次1-2小时，滤过，滤液浓缩成在60-65℃测相对密度为1．10-1．25的清膏，加乙醇至使含乙醇量为60％，搅匀，静置，滤过，取滤液回收乙醇，浓缩成含固体重量65-67％的浸膏，加入蔗糖20％、炼蜜12％、防腐剂1-3％，原液灌封，辐照灭菌，包装成品，制成口服液，即得。
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| 分阶段辨证治疗肺脓肿疗效分析;吴庆庚;《河北中医》;19990228;第21卷(第2期);第77页左栏2.1.2节 * |
| 吴庆庚.分阶段辨证治疗肺脓肿疗效分析.《河北中医》.1999,第21卷(第2期), |
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