CN102670842A - Chinese medicament for treating diabetic nephropathy - Google Patents

Abstract

The invention provides a Chinese medicament for treating diabetic nephropathy, and belongs to the field of Chinese medicaments for treating renal and urogenital disorders, and the Chinese medicament has the advantages of good effect and quick response. The Chinese medicament is prepared from glossy privet fruit, pseudo-ginseng, Chinese angelica, rehmannia, ganoderma lucidum, medlar, gordon euryale seed and other raw materials, has the effects of reinforcing vital energy and consolidating constitution, invigorating vital energy and nourishing blood, replenishing vital essence and removing heat, clearing damp and promoting diuresis, and activating blood circulation and removing stasis, and has the advantages of remarkable effect and quick response.

Description

A kind of Chinese medicine of treatment of diabetic nephropathy

Technical field

The invention belongs to the field of Chinese medicines of treatment diseases of urinary system.

Background technology

According to statistics, at present among the nephrotic of China, about 52% is diabetic nephropathy, is a sizable illness colony.Diabetic nephropathy is due to diabetes complicated glomerular microangiopathy becomes, to be one of lethal major reason of diabetes.Diabetics about 20% is died from this disease.Be intended to the field of Chinese medicines of treatment of diabetic nephropathy at present, have the shortcoming of two aspects: the one, effect is obvious inadequately; The 2nd, it is slower to take effect, and large quantities of diabetic nephropathy patient are owing to can not get the treatment of active drug, and nephropathy constantly develops, and constantly worsens, and becomes renal failure, threat to life.Patient and family members are very dissatisfied.

To problem set forth above, the present invention provides a kind of Chinese medicine of treatment of diabetic nephropathy, and it can solve, and this type of Chinese medicine effect was obvious inadequately in the past, the slower problem that takes effect, and effective, instant effect, it is definite to have drug effect, the advantage of quick result.

Summary of the invention

The present invention realizes through following technical scheme:

1, a kind of Chinese medicine of treatment of diabetic nephropathy adopts the raw material of Chinese medicine preparation, and the weight proportion of raw material of Chinese medicine is:

Fructus Ligustri Lucidi 3---10 parts of 5 portions of Radix Notoginseng 1---2 parts of Radix Angelicae Sinensis 6---

Radix Rehmanniae 6---7 parts of 10 portions of Ganodermas 6---10 parts of Fructus Lycii 4---

Semen Euryales 4---7 parts

The Chinese medicine of this treatment of diabetic nephropathy is processed by following method:

(1) by above-mentioned weight ratio, Fructus Ligustri Lucidi, Radix Angelicae Sinensis, Radix Rehmanniae, Ganoderma, Fructus Lycii, Semen Euryales are extracted through conventional water extraction process, process extractum, oven dry is pulverized, and gets the extract fine powder;

(2) by above-mentioned weight ratio, Radix Notoginseng is ground into fine powder, mixes, stir, process Chinese medicine granules, capsule, tablet with above-mentioned (1) extract fine powder.

The present invention is according to the folk tradition prescription, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling develops meticulously.We think that the most hypoimmunities of diabetics are given birth in the deficiency-heat, consume the body fluid that burns in research; Blood is hypercoagulability, and stickiness is bigger, and blood flow is slow; Cause the kidney blood supply insufficiency, the nephridial tissue microcirculation is not smooth, and this is the basic reason of kidney of diabetic patients generation microangiopathies.So, attach most importance to set upright, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, the damp eliminating diuretic should be the rule of treatment of treatment of diabetic nephropathy.Ganoderma, Fructus Lycii the body resistance strengthening and constitution consolidating in the side, benefiting QI and nourishing blood, tranquilizing by nourishing the heart, enhancing human body immunity power; Radix Angelicae Sinensis, pseudo-ginseng blood-circulation-invigovating blood stasis dispelling increase the kidney blood flow, improve renal microcirculation; Radix Rehmanniae property is sweet cold, is longer than nourishing YIN and clearing away heat, can separate due to quenching one's thirst scorching, again can be and blood stasis dispelling by arthralgia due to stagnation of blood; Be aided with the Fructus Ligustri Lucidi nourishing the liver and kidney, nourishing YIN to relieve dryness; The Semen Euryales the kidney invigorating and essence nourishing, spleen invigorating, damp eliminating.All medicine compatibilities bring out the best in each other, and play the body resistance strengthening and constitution consolidating altogether, benefiting QI and nourishing blood, and replenishing YIN and removing heat, promoting diuresis to eliminate damp pathogen, the merit of blood circulation promoting and blood stasis dispelling, effective, instant effect, it is definite to have drug effect, the advantage of quick result.

The specific embodiment

Through following embodiment the present invention is done and to specify:

1, get following prescription (weight is unit by gram):

Fructus Ligustri Lucidi 300 gram Radix Notoginseng 100 gram Radix Angelicae Sinensis 600 grams

Radix Rehmanniae 600 kairine sesames 600 gram Fructus Lycii 400 grams

Semen Euryales 400 grams

Press predetermined weight, Fructus Ligustri Lucidi, Radix Angelicae Sinensis, Radix Rehmanniae, Ganoderma, Fructus Lycii, Semen Euryales are extracted, process extract fine powder 290 grams altogether with conventional water extraction process; Radix Notoginseng is ground into fine powder, mixes, stir with said extracted thing fine powder; Process fine particle; The capsule of packing into No. 0 is processed 1300 of Chinese medicinal capsules, and every capsules includes Chinese medicine fine powder and extract 0.3 gram.

2, get following prescription (weight is unit by gram):

Fructus Ligustri Lucidi 500 gram Radix Notoginseng 180 gram Radix Angelicae Sinensis 1000 grams

Radix Rehmanniae 1000 kairine sesames 1000 gram Fructus Lycii 700 grams

Semen Euryales 700 grams

By above-mentioned same method, process 2233 of Chinese medicinal capsules, every capsules includes Chinese medicine fine powder and extract 0.3 gram.

3, get following prescription (by weight):

8 parts of 1 part of Radix Angelicae Sinensis of 3 portions of Radix Notoginseng of Fructus Ligustri Lucidi

4 parts of 8 parts of Fructus Lycii of 8 portions of Ganodermas of Radix Rehmanniae

4 parts of Semen Euryaless

By above-mentioned same method, process Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.3 gram.

4, get following prescription (by weight):

9 parts of 2 parts of Radix Angelicae Sinensis of 4 portions of Radix Notoginseng of Fructus Ligustri Lucidi

6 parts of 9 parts of Fructus Lycii of 9 portions of Ganodermas of Radix Rehmanniae

6 parts of Semen Euryaless

By above-mentioned same method, process Chinese medicinal capsule, every capsules includes Chinese medicine fine powder and extract 0.3 gram.

Clinical data:

The present invention is an example with traditional Chinese medical science diabetic nephropathy, through 24 routine clinical observations.Selecting the tcm diagnosis diabetic nephropathy is standard: diabetics has thirsty, polydipsia, frequent micturition, urgent micturition, spiritlessness and weakness, and edema of lower limbs has albuminuria, serum creatinine (scr) 133 ~ 442 μ mol/L.As above symptom can be made a definite diagnosis.In making a definite diagnosis the object of observation, male's 12 examples, women's 12 examples do not have other serious disease, and the age is 42 years old-78 years old, 60.6 years old mean age.

Efficacy determination:

1, produce effects: body constitution strengthens, on one's body energetically; Polydipsia polyuria, urine urgency-frequency disappear; Edema of lower limbs is alleviated; Albuminuria obviously reduces, and serum creatinine descends more than 10%.

2, effective: the polydipsia polyuria reduces to some extent, and on one's body energetically, edema, albuminuria are alleviated to some extent.

3, invalid: the disease no change.

During clinical experiment, withdraw other medicines and health nutrient.Taking the Chinese medicinal capsule that the specific embodiment of the invention 2 is made, observed 6 months, is a course of treatment.Instructions of taking: every day 2 times, each 4 capsules, every capsules include Chinese medicine fine powder and extract 0.3 gram, warm water delivery service after meal, symptom promptly has alleviation after 1 month, take 6 months after, symptom is obviously improved.24 philtrums of clinical experiment, produce effects 11 people, effective 10 people, invalid 3 people, total effective rate 87.5%.

Claims (1)

1. the Chinese medicine of a treatment of diabetic nephropathy is characterized in that: said Chinese medicine is to adopt the raw material of Chinese medicine preparation, and the weight proportion of raw material of Chinese medicine is:

Fructus Ligustri Lucidi 3---10 parts of 5 portions of Radix Notoginseng 1---2 parts of Radix Angelicae Sinensis 6---

Radix Rehmanniae 6---7 parts of 10 portions of Ganodermas 6---10 parts of Fructus Lycii 4---

Semen Euryales 4---7 parts

The Chinese medicine of this treatment of diabetic nephropathy is processed by following method:

(1) by above-mentioned weight ratio, Fructus Ligustri Lucidi, Radix Angelicae Sinensis, Radix Rehmanniae, Ganoderma, Fructus Lycii, Semen Euryales are extracted through conventional water extraction process, process extractum, oven dry is pulverized, and gets the extract fine powder;

(2) by above-mentioned weight ratio, Radix Notoginseng is ground into fine powder, mixes, stir, process Chinese medicine granules, capsule, tablet with above-mentioned (1) extract fine powder.