CN103566183A - Medicament for treating diabetic nephropathy - Google Patents

Medicament for treating diabetic nephropathy Download PDF

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Publication number
CN103566183A
CN103566183A CN201310549249.3A CN201310549249A CN103566183A CN 103566183 A CN103566183 A CN 103566183A CN 201310549249 A CN201310549249 A CN 201310549249A CN 103566183 A CN103566183 A CN 103566183A
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China
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radix
herba
semen
diabetic nephropathy
fructus
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CN201310549249.3A
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Chinese (zh)
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王焕江
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Individual
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Abstract

The invention provides a medicament for treating diabetic nephropathy. The medicament is characterized by comprising the following components: 10-20 g of houttuynia cordata, 5-15 g of plantain, 6-12 g of glossy privet fruit, 6-12 g of pseudo-ginseng, 5-15 g of angelica, 10-20 g of rehmannia, 6-12 g of medlar and 5-15 g of gorgon fruit, and the like, and the medicament has the functions of supporting body resistance, cing qi and nourishing blood, nourishing yin and clearing heat, clearing damp and promoting diuresis and promoting blood circulation to remove blood stasis and has the advantages of exact curative effect and quickness for becoming effective.

Description

A kind of medicine for the treatment of of diabetic nephropathy
Technical field
The drug world that the invention belongs to treatment diseases of urinary system, specifically, relates to a kind of medicine for the treatment of of diabetic nephropathy.
Background technology
According to statistics, at present, in the nephrotic of China, approximately 52% is diabetic nephropathy, is a sizable illness colony.Diabetic nephropathy is, due to diabetes complicated glomerular microangiopathy becomes, to be one of lethal major reason of diabetes.Diabetics approximately 20% is died from this disease.Be intended at present the drug world for the treatment of of diabetic nephropathy, have the shortcoming of two aspects: the one, effect is obvious not; The 2nd, take effect slower, large quantities of diabetic nephropathy patient are owing to can not get the treatment of active drug, and nephropathy development, constantly worsens, and becomes renal failure, threat to life.Patient and family members are very dissatisfied.
Summary of the invention
For problem set forth above, the invention provides a kind of medicine for the treatment of of diabetic nephropathy, it can solve, and this type of effect of drugs was obvious not in the past, the slower problem that takes effect, effective, instant effect, has drug effect definite, the advantage of quick result.
The present invention is achieved through the following technical solutions:
A medicine for treatment of diabetic nephropathy, is characterized in that, described medicine comprises following component:
Herba Houttuyniae 10-20g, Herba Plantaginis 5-15g, Fructus Ligustri Lucidi 6-12g, Radix Notoginseng 6-12g, Radix Angelicae Sinensis 5-15g, Radix Rehmanniae 10-20g, Fructus Lycii 6-12g, Semen Euryales 5-15g, Radix orixae japonicae 6-12g, Semen Phaseoli 6-12g, Radix Puerariae 10-20g, Radix Ophiopogonis 5-15g, Herba Potentillae Discoloris 10-20g, Radix Astragali 10-20g, Rhizoma Coptidis 6-12g, Radix Trichosanthis 6-12g, winter folium mori 5-15g, Cortex Lycii 5-15g, Semen Cuscutae 6-12g, Rhizoma Polygonati 6-12g, Herba Epimedii 6-12g, Radix Glycyrrhizae 6-12g.
Preferably, described medicine comprises following component:
Herba Houttuyniae 15g, Herba Plantaginis 10g, Fructus Ligustri Lucidi 9g, Radix Notoginseng 9g, Radix Angelicae Sinensis 10g, Radix Rehmanniae 15g, Fructus Lycii 9g, Semen Euryales 10g, Radix orixae japonicae 9g, Semen Phaseoli 9g, Radix Puerariae 15g, Radix Ophiopogonis 10g, Herba Potentillae Discoloris 15g, Radix Astragali 15g, Rhizoma Coptidis 9g, Radix Trichosanthis 9g, winter folium mori 10g, Cortex Lycii 10g, Semen Cuscutae 9g, Rhizoma Polygonati 9g, Herba Epimedii 9g, Radix Glycyrrhizae 9g.
Optionally, described medicine comprises following component:
Herba Houttuyniae 10g, Herba Plantaginis 5g, Fructus Ligustri Lucidi 6g, Radix Notoginseng 6g, Radix Angelicae Sinensis 5g, Radix Rehmanniae 10g, Fructus Lycii 6g, Semen Euryales 5g, Radix orixae japonicae 6g, Semen Phaseoli 6g, Radix Puerariae 10g, Radix Ophiopogonis 5g, Herba Potentillae Discoloris 10g, Radix Astragali 10g, Rhizoma Coptidis 6g, Radix Trichosanthis 6g, winter folium mori 5g, Cortex Lycii 5g, Semen Cuscutae 6g, Rhizoma Polygonati 6g, Herba Epimedii 6g, Radix Glycyrrhizae 6g.
Optionally, described medicine comprises following component:
Herba Houttuyniae 20g, Herba Plantaginis 15g, Fructus Ligustri Lucidi 12g, Radix Notoginseng 12g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 20g, Fructus Lycii 12g, Semen Euryales 15g, Radix orixae japonicae 12g, Semen Phaseoli 12g, Radix Puerariae 20g, Radix Ophiopogonis 15g, Herba Potentillae Discoloris 20g, Radix Astragali 20g, Rhizoma Coptidis 12g, Radix Trichosanthis 12g, winter folium mori 15g, Cortex Lycii 15g, Semen Cuscutae 12g, Rhizoma Polygonati 12g, Herba Epimedii 12g, Radix Glycyrrhizae 12g.
The present invention is according to folk tradition formula, and the theory according to traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling, develops meticulously.We think in research, and the most hypoimmunities of diabetics are raw in deficiency-heat, consume the body fluid that burns, blood is hypercoagulability, and stickiness is larger, and blood flow is slow, cause kidney blood supply insufficiency, nephridial tissue microcirculation is not smooth, and this is the basic reason of kidney of diabetic patients generation microangiopathies.So, with righting, attach most importance to, benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, damp eliminating diuretic should be the rule for the treatment of of treatment of diabetic nephropathy.
The specific embodiment
Embodiment 1: a kind of medicine for the treatment of of diabetic nephropathy, and described medicine comprises following component:
Herba Houttuyniae 15g, Herba Plantaginis 10g, Fructus Ligustri Lucidi 9g, Radix Notoginseng 9g, Radix Angelicae Sinensis 10g, Radix Rehmanniae 15g, Fructus Lycii 9g, Semen Euryales 10g, Radix orixae japonicae 9g, Semen Phaseoli 9g, Radix Puerariae 15g, Radix Ophiopogonis 10g, Herba Potentillae Discoloris 15g, Radix Astragali 15g, Rhizoma Coptidis 9g, Radix Trichosanthis 9g, winter folium mori 10g, Cortex Lycii 10g, Semen Cuscutae 9g, Rhizoma Polygonati 9g, Herba Epimedii 9g, Radix Glycyrrhizae 9g.
Embodiment 2: a kind of medicine for the treatment of of diabetic nephropathy, and described medicine comprises following component:
Herba Houttuyniae 10g, Herba Plantaginis 5g, Fructus Ligustri Lucidi 6g, Radix Notoginseng 6g, Radix Angelicae Sinensis 5g, Radix Rehmanniae 10g, Fructus Lycii 6g, Semen Euryales 5g, Radix orixae japonicae 6g, Semen Phaseoli 6g, Radix Puerariae 10g, Radix Ophiopogonis 5g, Herba Potentillae Discoloris 10g, Radix Astragali 10g, Rhizoma Coptidis 6g, Radix Trichosanthis 6g, winter folium mori 5g, Cortex Lycii 5g, Semen Cuscutae 6g, Rhizoma Polygonati 6g, Herba Epimedii 6g, Radix Glycyrrhizae 6g.
Embodiment 3: a kind of medicine for the treatment of of diabetic nephropathy, and described medicine comprises following component:
Herba Houttuyniae 20g, Herba Plantaginis 15g, Fructus Ligustri Lucidi 12g, Radix Notoginseng 12g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 20g, Fructus Lycii 12g, Semen Euryales 15g, Radix orixae japonicae 12g, Semen Phaseoli 12g, Radix Puerariae 20g, Radix Ophiopogonis 15g, Herba Potentillae Discoloris 20g, Radix Astragali 20g, Rhizoma Coptidis 12g, Radix Trichosanthis 12g, winter folium mori 15g, Cortex Lycii 15g, Semen Cuscutae 12g, Rhizoma Polygonati 12g, Herba Epimedii 12g, Radix Glycyrrhizae 12g.
In addition, the manufacture method of above-described embodiment Chinese medicine: selection according to quantity, with conventional water extraction process, medicine is extracted respectively, extract is mixed, stir, make fine particle, pack capsule into No. 0, make medicament capsule.
Clinical data:
The present invention be take traditional Chinese medical science diabetic nephropathy as example, through 24 routine clinical observations.Selecting tcm diagnosis diabetic nephropathy is standard: diabetics has thirsty, polydipsia, frequent micturition, urgent micturition, spiritlessness and weakness, and edema of lower limbs, has albuminuria, serum creatinine (scr) 133,442u mol/L.As above symptom, can make a definite diagnosis.In making a definite diagnosis the object of observation, male's 12 examples, women's 12 examples, without other serious disease, the age is 42 years old-78 years old, 60.6 years old mean age.
Efficacy determination:
1, effective: body constitution strengthens, with it energetically; Polydipsia polyuria, urine urgency-frequency disappear; Edema of lower limbs is alleviated; Albuminuria obviously reduces, and serum creatinine declines more than 10%.
2, effective: polydipsia polyuria reduces to some extent, and with it energetically, edema, albuminuria are alleviated to some extent.
3, invalid: disease is unchanged.
During clinical experiment, withdraw other medicines and health nutrient.Taking the medicament capsule that the specific embodiment of the invention 2 is made, observe 6 months, is a course for the treatment of.Instructions of taking: every day 2 times, each 4 capsules, every capsules includes 0.3 gram of fine drug powder and extract, warm water delivery service after meal, after 1 month, symptom has alleviation, takes after 6 months, and symptom is obviously improved.In 24 people of clinical experiment, effective 11 people, effective 10 people, invalid 3 people, total effective rate 87.5%.

Claims (4)

1. a medicine for treatment of diabetic nephropathy, is characterized in that, described medicine comprises following component:
Herba Houttuyniae 10-20g, Herba Plantaginis 5-15g, Fructus Schisandrae Chinensis 6-12g, Cornu Cervi Degelatinatum 6-12g, Radix Angelicae Sinensis 5-15g, Radix Rehmanniae 10-20g, Fructus Lycii 6-12g, Semen Euryales 5-15g, Radix orixae japonicae 6-12g, Semen Phaseoli 6-12g, Radix Puerariae 10-20g, Radix Ophiopogonis 5-15g, Herba Potentillae Discoloris 10-20g, Radix Astragali 10-20g, Rhizoma Coptidis 6-12g, Radix Trichosanthis 6-12g, winter folium mori 5-15g, Cortex Lycii 5-15g, Semen Cuscutae 6-12g, Rhizoma Polygonati 6-12g, Herba Epimedii 6-12g, Radix Glycyrrhizae 6-12g.
2. the medicine for the treatment of of diabetic nephropathy according to claim 1, is characterized in that, described medicine comprises following component:
Herba Houttuyniae 15g, Herba Plantaginis 10g, Fructus Ligustri Lucidi 9g, Radix Notoginseng 9g, Radix Angelicae Sinensis 10g, Radix Rehmanniae 15g, Fructus Lycii 9g, Semen Euryales 10g, Radix orixae japonicae 9g, Semen Phaseoli 9g, Radix Puerariae 15g, Radix Ophiopogonis 10g, Herba Potentillae Discoloris 15g, Radix Astragali 15g, Rhizoma Coptidis 9g, Radix Trichosanthis 9g, winter folium mori 10g, Cortex Lycii 10g, Semen Cuscutae 9g, Rhizoma Polygonati 9g, Herba Epimedii 9g, Radix Glycyrrhizae 9g.
3. the medicine for the treatment of of diabetic nephropathy according to claim 1, is characterized in that, described medicine comprises following component:
Herba Houttuyniae 10g, Herba Plantaginis 5g, Fructus Ligustri Lucidi 6g, Radix Notoginseng 6g, Radix Angelicae Sinensis 5g, Radix Rehmanniae 10g, Fructus Lycii 6g, Semen Euryales 5g, Radix orixae japonicae 6g, Semen Phaseoli 6g, Radix Puerariae 10g, Radix Ophiopogonis 5g, Herba Potentillae Discoloris 10g, Radix Astragali 10g, Rhizoma Coptidis 6g, Radix Trichosanthis 6g, winter folium mori 5g, Cortex Lycii 5g, Semen Cuscutae 6g, Rhizoma Polygonati 6g, Herba Epimedii 6g, Radix Glycyrrhizae 6g.
4. the medicine for the treatment of of diabetic nephropathy according to claim 1, is characterized in that, described medicine comprises following component:
Herba Houttuyniae 20g, Herba Plantaginis 15g, Fructus Ligustri Lucidi 12g, Radix Notoginseng 12g, Radix Angelicae Sinensis 15g, Radix Rehmanniae 20g, Fructus Lycii 12g, Semen Euryales 15g, Radix orixae japonicae 12g, Semen Phaseoli 12g, Radix Puerariae 20g, Radix Ophiopogonis 15g, Herba Potentillae Discoloris 20g, Radix Astragali 20g, Rhizoma Coptidis 12g, Radix Trichosanthis 12g, winter folium mori 15g, Cortex Lycii 15g, Semen Cuscutae 12g, Rhizoma Polygonati 12g, Herba Epimedii 12g, Radix Glycyrrhizae 12g.
CN201310549249.3A 2013-10-30 2013-10-30 Medicament for treating diabetic nephropathy Pending CN103566183A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177416A (en) * 2016-08-24 2016-12-07 楚雄医药高等专科学校 A kind of traditional Chinese medicinal composition with effect of reducing blood sugar and preparation method thereof
CN106389965A (en) * 2016-11-11 2017-02-15 郭仕玖 Traditional Chinese medicine composition for treating diabetes and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177416A (en) * 2016-08-24 2016-12-07 楚雄医药高等专科学校 A kind of traditional Chinese medicinal composition with effect of reducing blood sugar and preparation method thereof
CN106177416B (en) * 2016-08-24 2019-05-10 楚雄医药高等专科学校 A kind of traditional Chinese medicinal composition with effect of reducing blood sugar and preparation method thereof
CN106389965A (en) * 2016-11-11 2017-02-15 郭仕玖 Traditional Chinese medicine composition for treating diabetes and preparation method thereof

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Application publication date: 20140212